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58 条记录 (耗时 0.056 秒)

    Expandable Implant and Implant System
    3.
    发明申请
    Expandable Implant and Implant System 有权
    可扩展植入物和植入系统

    公开(公告)号：US20120158034A1

    公开(公告)日：2012-06-21

    申请号：US13325906

    申请日：2011-12-14

    申请人： Thomas S. Wilson ,  Ward Small, IV ,  William J. Benett ,  Jason M. Ortega ,  Duncan J. Maitland ,  Jonathan Hartman

    发明人： Thomas S. Wilson ,  Ward Small, IV ,  William J. Benett ,  Jason M. Ortega ,  Duncan J. Maitland ,  Jonathan Hartman

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12113 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12163 ,  A61B17/12181 ,  A61B2017/00871 ,  A61B2017/12054 ,  A61M25/0668 ,  A61M2025/0042

    摘要： An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.

    摘要翻译： 本发明的一个实施方案包括可扩张植入物以血管内栓塞解剖空洞或畸形，例如动脉瘤。 一个实施方案由可扩张聚合物泡沫元件的链或连接序列组成。 另一个实施方案包括连接到骨架的细长长度的可发性聚合物泡沫。 另一实施例包括用于栓塞动脉瘤的可扩张植入物（例如，形状记忆聚合物）的血管内递送的系统。 系统可以包括微导管，联接到微导管的远端的管腔减小套管，可拆卸地联接到可扩张植入物的柔性推动元件，以及柔性管状护套，内部压缩的植入物和推动元件被预加载 。 本文描述了其它实施例。

    Microfabricated therapeutic actuators and release mechanisms therefor
    7.
    发明授权
    Microfabricated therapeutic actuators and release mechanisms therefor 失效
    微型治疗执行器及其释放机制

    公开(公告)号：US6059815A

    公开(公告)日：2000-05-09

    申请号：US67824

    申请日：1998-04-28

    申请人： Abraham P. Lee ,  Joseph P. Fitch ,  Daniel L. Schumann ,  Luiz Da Silva ,  William J. Benett ,  Peter A. Krulevitch

    发明人： Abraham P. Lee ,  Joseph P. Fitch ,  Daniel L. Schumann ,  Luiz Da Silva ,  William J. Benett ,  Peter A. Krulevitch

    IPC分类号： A61B17/00 ,  A61B17/12 ,  A61M25/16 ,  A61B17/28

    CPC分类号： A61B17/1214 ,  A61B17/12022 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/12068 ,  A61B2017/12077

    摘要： Microfabricated therapeutic actuators are fabricated using a shape memory polymer (SMP), a polyurethane-based material that undergoes a phase transformation at a specified temperature (Tg). At a temperature above temperature Tg material is soft and can be easily reshaped into another configuration. As the temperature is lowered below temperature Tg the new shape is fixed and locked in as long as the material stays below temperature Tg. Upon reheating the material to a temperature above Tg, the material will return to its original shape. By the use of such SMP material, SMP microtubing can be used as a retaining/release actuator for the delivery of material, such as embolic coils, for example, through catheters into aneurysms, for example. The microtubing can be manufactured in various sizes and the phase change temperature Tg is determinate for an intended temperature target and intended use. The SMP microtubing can be positioned around or within an end of a deposit material. Various heating arrangements can be utilized with the SMP release mechanism, and the SMP microtubing can include a metallic coating for enhanced light absorption.

    摘要翻译： 使用形状记忆聚合物（SMP），在特定温度（Tg）下经历相变的基于聚氨酯的材料制造微制剂治疗致动器。 在高于温度的温度下，Tg材料是柔软的并且可以容易地重塑成另一种构型。 当温度降低到温度Tg以下时，只要材料保持低于温度Tg，新形状就会被固定和锁定。 将材料重新加热至高于Tg的温度时，材料将恢复到原来的形状。 通过使用这种SMP材料，SMP微管可用作用于例如通过导管穿入动脉瘤等物质输送的保持/释放致动器。 微管可以以各种尺寸制造，相变温度Tg对于预期的温度目标和预期用途是确定的。 SMP微管可以定位在沉积材料的周围或内部。 SMP释放机构可以使用各种加热装置，并且SMP微管可以包括用于增强光吸收的金属涂层。

    Apparatus for loading shape memory gripper mechanisms
    8.
    发明授权
    Apparatus for loading shape memory gripper mechanisms 失效
    装载形状记忆夹持机构的装置

    公开(公告)号：US06240630B1

    公开(公告)日：2001-06-05

    申请号：US08984624

    申请日：1997-12-03

    申请人： Abraham P. Lee ,  William J. Benett ,  Daniel L. Schumann ,  Peter A. Krulevitch ,  Joseph P. Fitch

    发明人： Abraham P. Lee ,  William J. Benett ,  Daniel L. Schumann ,  Peter A. Krulevitch ,  Joseph P. Fitch

    IPC分类号： B21D3904

    CPC分类号： A61B17/221 ,  A61B17/1219 ,  A61B2017/00345 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/1205 ,  A61B2017/12068 ,  A61B2017/12072 ,  Y10T29/49865 ,  Y10T29/49929 ,  Y10T29/53439 ,  Y10T29/53987

    摘要： A method and apparatus for loading deposit material, such as an embolic coil, into a shape memory polymer (SMP) gripping/release mechanism. The apparatus enables the application of uniform pressure to secure a grip by the SMP mechanism on the deposit material via differential pressure between, for example, vacuum within the SMP mechanism and hydrostatic water pressure on the exterior of the SMP mechanism. The SMP tubing material of the mechanism is heated to above the glass transformation temperature (Tg) while reshaping, and subsequently cooled to below Tg to freeze the shape. The heating and/or cooling may, for example, be provided by the same water applied for pressurization or the heating can be applied by optical fibers packaged to the SMP mechanism for directing a laser beam, for example, thereunto. At a point of use, the deposit material is released from the SMP mechanism by reheating the SMP material to above the temperature Tg whereby it returns to its initial shape. The reheating of the SM material may be carried out by injecting heated fluid (water) through an associated catheter or by optical fibers and an associated beam of laser light, for example.

    摘要翻译： 一种用于将诸如栓塞线圈的沉积材料装载到形状记忆聚合物（SMP）夹持/释放机构中的方法和装置。 该装置能够通过例如SMP机构中的真空和SMP机构的外部上的静水压力之间的压差来施加均匀的压力，以通过SMP机构来确保在沉积材料上的握持。 将机构的SMP管材料加热至高于玻璃化转变温度（Tg），同时重塑，随后冷却至Tg以下以冻结形状。 加热和/或冷却可以例如由施加加压的相同的水提供，或者可以通过包封在SMP机构中的光纤施加加热，以引导例如激光束。 在使用时，通过将SMP材料再加热到高于Tg的温度Tg，沉积材料从SMP机制释放，由此其恢复到初始形状。 SM材料的再加热可以通过例如通过相关联的导管或通过光纤和相关的激光束注入加热的流体（水）来进行。

    Method for loading shape memory polymer gripper mechanisms
    9.
    发明授权
    Method for loading shape memory polymer gripper mechanisms 有权

    公开(公告)号：US06370757B1

    公开(公告)日：2002-04-16

    申请号：US09568615

    申请日：2000-05-10

    申请人： Abraham P. Lee ,  William J. Benett ,  Daniel L. Schumann ,  Peter A. Krulevitch ,  Joseph P. Fitch

    发明人： Abraham P. Lee ,  William J. Benett ,  Daniel L. Schumann ,  Peter A. Krulevitch ,  Joseph P. Fitch

    IPC分类号： B23P1102

    摘要： A method and apparatus for loading deposit material, such as an embolic coil, into a shape memory polymer (SMP) gripping/release mechanism. The apparatus enables the application of uniform pressure to secure a grip by the SMP mechanism on the deposit material via differential pressure between, for example, vacuum within the SMP mechanism and hydrostatic water pressure on the exterior of the SMP mechanism. The SMP tubing material of the mechanism is heated to above the glass transformation temperature (Tg) while reshaping, and subsequently cooled to below Tg to freeze the shape. The heating and/or cooling may, for example, be provided by the same water applied for pressurization or the heating can be applied by optical fibers packaged to the SMP mechanism for directing a laser beam, for example, thereunto. At a point of use, the deposit material is released from the SMP mechanism by reheating the SMP material to above the temperature Tg whereby it returns to its initial shape. The reheating of the SMP material may be carried out by injecting heated fluid (water) through an associated catheter or by optical fibers and an associated beam of laser light, for example.