公开(公告)号：US06645145B1

公开(公告)日：2003-11-11

申请号：US09962427

申请日：2001-09-24

申请人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp ,  Sevig Ayter

发明人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp ,  Sevig Ayter

IPC分类号： A61B800

CPC分类号： B06B1/00 ,  A61B8/445 ,  A61B8/4483 ,  H01H59/0009

摘要： The use of any micro-mechanical component in an ultrasound system is disclosed. In particular, the use of micro-mechanical ultrasound transducers, micro-relays, micro-switches and inductors in the transducer probe head, in the transducer connector, coupled with the system transducer connector(s) or anywhere else in the system. In an ultrasound system, micro-mechanical components such as micro-mechanical ultrasound transducers, micro-fabricated switches, relays and inductors permit impressive size reduction, cost reduction, signal-integrity enhancement and improved operational flexibility.

摘要翻译： 公开了在超声系统中使用任何微机械部件。 特别地，在换能器探头中，在换能器连接器中使用微机械超声换能器，微型继电器，微型开关和电感器，与系统换能器连接器或系统中的任何其他地方相结合。 在超声系统中，诸如微机械超声换能器，微型开关，继电器和电感器的微机械组件允许显着的尺寸减小，成本降低，信号完整性增强和改进的操作灵活性。

公开(公告)号：US06773401B1

公开(公告)日：2004-08-10

申请号：US09824314

申请日：2001-04-02

申请人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp

发明人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp

IPC分类号： A61B800

CPC分类号： B06B1/00 ,  A61B8/4483 ,  H01H59/0009

摘要： The use of any micro-mechanical component in an ultrasound system is disclosed. In particular, the use of micro-relays, micro-switches and inductors in the transducer probe head, in the transducer connector, coupled with the system transducer connector(s) or anywhere else in the system. In an ultrasound system, micro-mechanical components such as micro-fabricated switches, relays and inductors permit impressive size reduction, cost reduction, signal-integrity enhancement and improved operational flexibility.

摘要翻译： 公开了在超声系统中使用任何微机械部件。 特别地，在换能器探头中，在换能器连接器中使用微型继电器，微型开关和电感器，与系统换能器连接器或系统中的任何其他地方相结合。 在超声系统中，诸如微型开关，继电器和电感器的微机械部件允许显着的尺寸减小，成本降低，信号完整性增强和改进的操作灵活性。

公开(公告)号：US07549962B2

公开(公告)日：2009-06-23

申请号：US10368774

申请日：2003-02-18

申请人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp

发明人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp

IPC分类号： A61B8/00

CPC分类号： B06B1/00 ,  A61B8/4483 ,  H01H59/0009

摘要： The use of any micro-mechanical component in an ultrasound system is disclosed. In particular, the use of micro-relays, micro-switches and inductors in the transducer probe head, in the transducer connector, coupled with the system transducer connector(s) or anywhere else in the system. In an ultrasound system, micro-mechanical components such as micro-fabricated switches, relays and inductors permit impressive size reduction, cost reduction, signal-integrity enhancement and improved operational flexibility.

摘要翻译： 公开了在超声系统中使用任何微机械部件。 特别地，在换能器探头中，在换能器连接器中使用微型继电器，微型开关和电感器，与系统换能器连接器或系统中的任何其他地方相结合。 在超声系统中，诸如微型开关，继电器和电感器的微机械部件允许显着的尺寸减小，成本降低，信号完整性增强和改进的操作灵活性。

公开(公告)号：US06605043B1

公开(公告)日：2003-08-12

申请号：US09223257

申请日：1998-12-30

申请人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp

发明人： William R. Dreschel ,  Terry Kling ,  John W. Sliwa ,  Stuart L. Carp

IPC分类号： A61B801

CPC分类号： B06B1/00 ,  A61B8/4483 ,  H01H59/0009

摘要： The use of any micro-mechanical component in an ultrasound system is disclosed. In particular, the use of micro-relays, micro-switches and inductors in the transducer probe head, in the transducer connector, coupled with the system transducer connector(s) or anywhere else in the system. In an ultrasound system, micro-mechanical components such as micro-fabricated switches, relays and inductors permit impressive size reduction, cost reduction, signal-integrity enhancement and improved operational flexibility.

公开(公告)号：US06368275B1

公开(公告)日：2002-04-09

申请号：US09414235

申请日：1999-10-07

申请人： John W. Sliwa ,  William R. Dreschel

发明人： John W. Sliwa ,  William R. Dreschel

IPC分类号： A61B800

CPC分类号： A61B5/0031 ,  A61B5/01 ,  A61B5/0215 ,  A61B2562/028

摘要： A micro-instrument suitable for property imaging in a body is less than one millimeter in each dimension. The micro-instrument includes a base having a first wall and a second wall, the second wall substantially circumscribing the first wall, and a lid connected with the base to form a cavity and the lid being temporarily deformable. Optionally, the lid can include a cantilever that is deformable. Also optionally, an electronic circuit can be attached with the micro-instrument. The micro-instrument can also be substantially spherical. An observable property of the micro-instrument varies as a function of a physiological property of the body.

摘要翻译： 适用于身体物性成像的微型仪器在每个维度上均小于1毫米。 微型仪器包括具有第一壁和第二壁的基座，第二壁基本上围绕第一壁，以及与基座连接以形成空腔的盖，并且盖暂时可变形。 可选地，盖可以包括可变形的悬臂。 也可选地，电子电路可以与微型仪器连接。 微型仪器也可以是基本上球形的。 微器械的可观察性质随着身体的生理特性而变化。

公开(公告)号：US08864757B2

公开(公告)日：2014-10-21

申请号：US12347607

申请日：2008-12-31

申请人： Gleb V. Klimovitch ,  John W. Sliwa

发明人： Gleb V. Klimovitch ,  John W. Sliwa

IPC分类号： A61B18/18 ,  A61B18/04 ,  A61B17/42 ,  A61B17/46 ,  A61D1/10 ,  A61B8/00 ,  A61B5/04 ,  A61B18/14 ,  A61B5/00 ,  A61B5/042 ,  A61B18/02 ,  A61B19/00 ,  A61N7/02 ,  A61B18/24

CPC分类号： A61B5/6885 ,  A61B5/042 ,  A61B8/12 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/24 ,  A61B2090/065 ,  A61B2218/002 ,  A61N1/05 ,  A61N7/022

摘要： A contact sensing assembly including a catheter including an electrode having a base portion mounted adjacent a head portion of the catheter body. A sensor is disposed adjacent the base portion for measuring compression or tensile forces applied to an electrode tip portion, and includes a predetermined sensitivity. The base and head portions include predetermined rigidity so that forces applied to the electrode tip portion are determinable as a function of the sensitivity and a sensor output. A contact sensing assembly also includes an electrode pipe operatively connected to the catheter body for movement and bending with the catheter body, and an electrode wire disposed in the electrode pipe and including insulation. A change in capacitance resulting from movement of the electrode wire toward the electrode pipe or contact of the electrode wire with the electrode pipe during bending of the catheter correlates to a force applied to the catheter.

摘要翻译： 一种接触检测组件，包括导管，其包括具有邻近导管主体的头部安装的基部的电极。 传感器邻近基部设置，用于测量施加到电极末端部分的压缩或拉伸力，并且包括预定的灵敏度。 基部和头部包括预定的刚度，使得施加到电极末端部分的力可以根据灵敏度和传感器输出来确定。 接触检测组件还包括可操作地连接到导管主体的用于与导管主体一起移动和弯曲的电极管，以及设置在电极管中并包括绝缘体的电极线。 在导管弯曲期间由电极线向电极管的移动或电极线与电极管的接触的电容变化与施加于导管的力相关。

公开(公告)号：US07877854B2

公开(公告)日：2011-02-01

申请号：US11958862

申请日：2007-12-18

申请人： John W. Sliwa ,  John P. Goetz ,  Zhenyi Ma

发明人： John W. Sliwa ,  John P. Goetz ,  Zhenyi Ma

IPC分类号： H04R31/00

CPC分类号： G10K11/30 ,  Y10T29/49005 ,  Y10T29/49007 ,  Y10T29/4908 ,  Y10T29/49172 ,  Y10T29/49194

摘要： A focused ultrasound transducer includes a first ultrasonic emitter and at least one metallic ultrasonic lens acoustically coupled thereto. The emitter generates ultrasonic energy that propagates along a beam path projecting therefrom. The at least one metallic ultrasonic lens is positioned at least partially in the beam path so that it can direct (e.g., focus, defocus, and/or collimate) in at least one direction (or along at least one plane) at least some of the ultrasonic energy propagating from the emitter. The metallic lens may be formed by extrusion, by molding (e.g., diecast molding or thermoforming), or by sintering (e.g., powder metallurgy). The metallic lens also advantageously functions as a heat sink, improving thermal performance of the ultrasound transducer.

摘要翻译： 聚焦超声波换能器包括第一超声波发射器和声耦合到其上的至少一个金属超声波透镜。 发射器产生沿着从其突出的光束路径传播的超声波能量。 至少一个金属超声波透镜至少部分地定位在光束路径中，使得其可以在至少一个方向（或沿着至少一个平面）上引导（例如，聚焦，散焦和/或准直）至少一个 超声能量从发射器传播。 金属透镜可以通过挤出，模制（例如，压铸模塑或热成型）或通过烧结（例如粉末冶金）形成。 金属透镜还有利地用作散热器，从而改善超声换能器的热性能。

公开(公告)号：US20100233021A1

公开(公告)日：2010-09-16

申请号：US12381423

申请日：2009-03-11

申请人： John W. Sliwa ,  George W. Keilman ,  Bryan T. Oronsky ,  Carol A. Tosaya ,  Herbert L. Berman

发明人： John W. Sliwa ,  George W. Keilman ,  Bryan T. Oronsky ,  Carol A. Tosaya ,  Herbert L. Berman

IPC分类号： A61L2/10 ,  A61L2/03 ,  A61L2/025 ,  A61N1/32

CPC分类号： A61M25/0017 ,  A61B90/70 ,  A61M27/00 ,  A61M37/00 ,  A61M2025/0019 ,  A61N1/205 ,  A61N1/32 ,  A61N1/40

摘要： Disclosed are methods of inhibiting, avoiding or destroying existing, potential or incipient biodeposits, biofilms or pathogens any of (a) in or on a living body including in or on a medical device or implement placed, inserted or insertable in the body, (b) in, on or in contact with an ex vivo bodily tissue or fluid, or (c) in, on or in contact with a medium or matter to be consumed, ingested by or exposed to a living being or entity. Also disclosed are medical devices, implements, and prostheses that can be kept in a safe defouled, pathogen-free or pathogen-reduced condition with the help of an electric field(s). Also disclosed are medical or industrial devices, implements, equipment-articles and storage/handling-entities that can be kept in a safely defouled, pathogen-free or pathogen-reduced condition with the help of a membrane or orifice that has one or more of the antifouling or antipathogenic attributes.

摘要翻译： 公开了抑制，避免或破坏现有的，潜在的或初期的生物沉积物，生物膜或病原体（a）在生物体内或之上的生物体，包括在放置，插入或插入体内的医疗装置或器具中或之上，（b） ）在离体身体组织或流体接触或接触时，或（c）在要消费的介质或物质中或与其接触或摄入或暴露于活体或实体时。 还公开了医疗装置，器具和假体，其可以在电场的帮助下保持在安全的防污染，无病原体或病原体减少的状态。 还公开了医疗或工业装置，器具，设备制品和储存/处理实体，其可以在具有一个或多个以下的膜或孔的帮助下保持在安全脱钩，无病原体或病原体减少的状态 防污或抗病原性。

公开(公告)号：US20100168620A1

公开(公告)日：2010-07-01

申请号：US12347607

申请日：2008-12-31

申请人： Gleb V. Klimovitch ,  John W. Sliwa

发明人： Gleb V. Klimovitch ,  John W. Sliwa

IPC分类号： A61B5/00

CPC分类号： A61B5/6885 ,  A61B5/042 ,  A61B8/12 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/24 ,  A61B2090/065 ,  A61B2218/002 ,  A61N1/05 ,  A61N7/022

摘要： A contact sensing assembly including a catheter including an electrode having a base portion mounted adjacent a head portion of the catheter body. A sensor is disposed adjacent the base portion for measuring compression or tensile forces applied to an electrode tip portion, and includes a predetermined sensitivity. The base and head portions include predetermined rigidity so that forces applied to the electrode tip portion are determinable as a function of the sensitivity and a sensor output. A contact sensing assembly also includes an electrode pipe operatively connected to the catheter body for movement and bending with the catheter body, and an electrode wire disposed in the electrode pipe and including isolation. A change in capacitance resulting from movement of the electrode wire toward the electrode pipe or contact of the electrode wire with the electrode pipe during bending of the catheter correlates to a force applied to the catheter.

摘要翻译： 一种接触检测组件，包括导管，其包括具有邻近导管主体的头部安装的基部的电极。 传感器邻近基部设置，用于测量施加到电极末端部分的压缩或拉伸力，并且包括预定的灵敏度。 基部和头部包括预定的刚度，使得施加到电极尖端部分的力可以作为灵敏度和传感器输出的函数来确定。 接触检测组件还包括可操作地连接到导管主体的电极管，用于与导管主体一起移动和弯曲，以及设置在电极管中并包括隔离的电极线。 在导管弯曲期间由电极线向电极管的移动或电极线与电极管的接触的电容变化与施加于导管的力相关。

公开(公告)号：US20100168569A1

公开(公告)日：2010-07-01

申请号：US12346132

申请日：2008-12-30

申请人： John W. Sliwa ,  Stephen A. Morse

发明人： John W. Sliwa ,  Stephen A. Morse

IPC分类号： A61B8/00 ,  A61B18/14

CPC分类号： A61B8/12 ,  A61B8/00 ,  A61B8/0841 ,  A61B8/4245 ,  A61B8/445 ,  A61B8/463 ,  A61B18/02 ,  A61B18/14 ,  A61B18/18 ,  A61B18/20 ,  A61B2090/3782 ,  A61B2090/3784 ,  A61N7/02 ,  A61N7/022

摘要： An ablation system comprises a tool including an shaft having proximal and distal end portions, a handle at the proximal end portion, and a lumen extending between the proximal and distal end portions. The system further includes an ablation subsystem comprised of an ablation element at the distal end portion of the shaft, and an ablation source connected to the ablation element. The system further includes an imaging subsystem comprising an ultrasound imaging transducer disposed proximate the ablation element. The transducer is pivotally attached to the shaft or the ablation element to allow the transducer to articulate between stowed and deployed positions. The imaging subsystem further comprises a processor connected to the transducer configured to receive image data acquired by the transducer, and to generate an image corresponding thereto. The imaging subsystem still further includes a display connected to the processor configured to display the generated image.

摘要翻译： 消融系统包括工具，其包括具有近端部分和远端部分的轴，在近端部分处的手柄以及在近端部分和远端部分之间延伸的内腔。 该系统还包括消融子系统，其包括在轴的远端部分处的消融元件和连接到消融元件的消融源。 该系统还包括成像子系统，其包括邻近消融元件设置的超声成像换能器。 换能器枢转地附接到轴或消融元件，以允许换能器在收起位置和展开位置之间铰接。 成像子系统还包括连接到换能器的处理器，其被配置为接收由换能器获取的图像数据，并且生成与其对应的图像。 成像子系统还包括连接到处理器的显示器，其被配置为显示生成的图像。