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公开(公告)号:US07361327B2
公开(公告)日:2008-04-22
申请号:US11206330
申请日:2005-08-17
CPC分类号: C01B37/04 , C01B39/54 , Y10S423/30
摘要: Novel zeolites are produced by combining a polar solute, a silicon or phosphorous source, and a structure directing agent. Surfactants and a hydrophobic solvent are added to the previously mixed three species and shaken to disperse the surfactants. The reverse microemulsion is stirred overnight, at about room temperature and then iced for five to ten minutes. A metal source is added vigorously shaken for about two minutes. The mixture is then aged for about two hours at about room temperature. A mineralizer is added and the resultant mixture aged for about two hours at about room temperature. The mixture is heated to about 180° C., for a suitable time period. The final novel product is then isolated.
摘要翻译: 通过组合极性溶质,硅或磷源和结构导向剂来制备新型沸石。 将表面活性剂和疏水性溶剂加入到先前混合的三种物质中并摇动以分散表面活性剂。 将反相微乳液在约室温下搅拌过夜,然后冰化5至10分钟。 将金属源剧烈振动约两分钟。 然后将混合物在约室温下老化约2小时。 加入矿化剂,所得混合物在约室温下老化约2小时。 将混合物加热至约180℃,持续合适的时间。 然后分离最终的新产品。
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公开(公告)号:US06949238B2
公开(公告)日:2005-09-27
申请号:US10360544
申请日:2003-02-05
CPC分类号: C01B37/04 , C01B39/54 , Y10S423/30
摘要: Novel zeolites are produced by combining a polar solute, a silicon or phosphorous source, and a structure directing agent. Surfactants and a hydrophobic solvent are added to the previously mixed three species and shaken to disperse the surfactants. The reverse microemulsion is stirred overnight, at about room temperature and then iced for five to ten minutes. A metal source is added vigorously shaken for about two minutes. The mixture is then aged for about two hours at about room temperature. A mineralizer is added and the resultant mixture aged for about two hours at about room temperature. The mixture is heated to about 180° C., for a suitable time period. The final novel product is then isolated.
摘要翻译: 通过组合极性溶质,硅或磷源和结构导向剂来制备新型沸石。 将表面活性剂和疏水性溶剂加入到先前混合的三种物质中并摇动以分散表面活性剂。 将反相微乳液在约室温下搅拌过夜,然后冰化5至10分钟。 将金属源剧烈振动约两分钟。 然后将混合物在约室温下老化约2小时。 加入矿化剂,所得混合物在约室温下老化约2小时。 将混合物加热至约180℃,持续合适的时间。 然后分离最终的新产品。
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公开(公告)号:US06176895B1
公开(公告)日:2001-01-23
申请号:US09185891
申请日:1998-11-04
申请人: Joseph M. DeSimone , William Tumas , Kimberly R. Powell , T. Mark McCleskey , Timothy J. Romack , James B. McClain , Eva R. Birnbaum
发明人: Joseph M. DeSimone , William Tumas , Kimberly R. Powell , T. Mark McCleskey , Timothy J. Romack , James B. McClain , Eva R. Birnbaum
IPC分类号: C22B326
CPC分类号: C22B3/0005 , C22B3/0097 , Y02P10/234
摘要: A composition useful for the extraction of metals and metalloids comprises (a) carbon dioxide fluid (preferably liquid or supercritical carbon dioxide); and (b) a polymer in the carbon dioxide, the polymer having bound thereto a ligand that binds the metal or metalloid; with the ligand bound to the polymer at a plurality of locations along the chain length thereof (i.e., a plurality of ligands are bound at a plurality of locations along the chain length of the polymer). The polymer is preferably a copolymer, and the polymer is preferably a fluoropolymer such as a fluoroacrylate polymer. The extraction method comprises the steps of contacting a first composition containing a metal or metalloid to be extracted with a second composition, the second composition being as described above; and then extracting the metal or metalloid from the first composition into the second composition.
摘要翻译: 用于萃取金属和准金属的组合物包括(a)二氧化碳流体(优选液体或超临界二氧化碳); 和(b)二氧化碳中的聚合物,所述聚合物结合有与金属或准金属结合的配体; 其中配体在其长度的多个位置处与聚合物结合(即,多个配体沿聚合物链长度的多个位置结合)。 聚合物优选为共聚物,聚合物优选为氟聚合物,例如氟代丙烯酸酯聚合物。 提取方法包括以下步骤:将含有待萃取的金属或准金属的第一组合物与第二组合物接触,第二组合物如上所述; 然后将金属或准金属从第一组合物提取到第二组合物中。
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公开(公告)号:US20080220441A1
公开(公告)日:2008-09-11
申请号:US11974156
申请日:2007-10-10
申请人: Eva R. Birnbaum , Andrew T. Koppisch , Sharon M. Baldwin , Benjamin P. Warner , T. Mark McCleskey , Jeffrey Joseph Stewart , Jennifer A. Berger , Michael N. Harris , Anthony K. Burrell
发明人: Eva R. Birnbaum , Andrew T. Koppisch , Sharon M. Baldwin , Benjamin P. Warner , T. Mark McCleskey , Jeffrey Joseph Stewart , Jennifer A. Berger , Michael N. Harris , Anthony K. Burrell
IPC分类号: G01N33/53 , G01N21/76 , G01N33/68 , G01N23/223
CPC分类号: G01N33/566 , G01N2500/04
摘要: X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical, for estimating the binding selectivity of a chemical versus chemical analogs, for measuring post-translational modifications of proteins, and for drug manufacturing.
摘要翻译: 已经使用X射线荧光(XRF)光谱法检测结合事件并测量化学物质和受体之间的结合选择性。 XRF还可用于估计化学品的治疗指数,用于估计化学品与化学类似物的结合选择性,用于测量蛋白质的翻译后修饰和药物制造。
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公开(公告)号:US20130034205A1
公开(公告)日:2013-02-07
申请号:US13567613
申请日:2012-08-06
申请人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L.E. Miller
发明人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L.E. Miller
IPC分类号: G01N1/28 , G01N23/223
CPC分类号: G01N23/2202 , G01N23/2204 , G01N23/223 , G01N2223/074 , G01N2223/076 , G01N2223/309 , G01N2223/64 , G03B42/02
摘要: An apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. A plate has one or more holes passing through the plate. The holes are covered by a film on one side of the plate. The holes are less than 500 micrometers across in one dimension where the film covers the holes. The film is translucent to x-rays.
摘要翻译: 通过X射线荧光光谱法制备用于测量的样品的装置。 板有一个或多个孔穿过板。 孔被板的一侧的薄膜覆盖。 在膜覆盖孔的一个维度上,孔小于500微米。 这部电影对于x射线是半透明的。
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公开(公告)号:US20090046832A1
公开(公告)日:2009-02-19
申请号:US12192762
申请日:2008-08-15
申请人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L.E. Miller
发明人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L.E. Miller
IPC分类号: G01N23/223
CPC分类号: G01N23/2202 , G01N23/2204 , G01N23/223 , G01N2223/074 , G01N2223/076 , G01N2223/309 , G01N2223/64 , G03B42/02
摘要: The present invention includes an apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. The apparatus comprises a plate having one or more holes passing through the plate. The holes are covered by a film on one side of the plate. The holes are less than 500 micrometers across in one dimension where the film covers the holes. The film is translucent to x-rays. The present invention also includes an apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. The apparatus comprises a plate having one or more holes passing through the plate. The holes are covered on one side of the plate by a detachable cover forming a water-tight seal against the plate. The cover is substantially free of the elements osmium, yttrium, iridium, phosphorus, zirconium, platinum, gold, niobium, mercury, thallium, molybdenum, sulfur, lead, bismuth, technetium, ruthenium, chlorine, rhodium, palladium, argon, silver, and thorium. The holes are less than about 500 micrometers across in one dimension where the cover covers the holes. The present invention also includes a method for preparing samples for measurement by x-ray fluorescence spectrometry. The method comprises providing a solution of with less than 10 micromolar solute and a volume of between about 2 microliters and about 2 milliliters. The solution is concentrated and analyzed using x-ray fluorescence spectrometry.
摘要翻译: 本发明包括通过X射线荧光光谱法制备用于测量的样品的装置。 该装置包括具有穿过板的一个或多个孔的板。 孔被板的一侧的薄膜覆盖。 在膜覆盖孔的一个维度上,孔小于500微米。 这部电影对于x射线是半透明的。 本发明还包括通过X射线荧光光谱法制备用于测量的样品的装置。 该装置包括具有穿过板的一个或多个孔的板。 孔通过可拆卸的盖子覆盖在板的一侧上,该盖子形成对板的防水密封。 该盖基本上不含锇,钇,铱,磷,锆,铂,金,铌,汞,铊,钼,硫,铅,铋,锝,钌,氯,铑,钯,氩, 和钍。 这些孔在一个尺寸上小于约500微米,其中盖覆盖孔。 本发明还包括通过X射线荧光光谱法制备用于测量的样品的方法。 该方法包括提供小于10微摩尔溶质的溶液和约2微升至约2毫升的体积。 使用x射线荧光光谱法浓缩溶液并进行分析。
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公开(公告)号:US20100003697A1
公开(公告)日:2010-01-07
申请号:US12496532
申请日:2009-07-01
申请人: Eva R. Birnbaum , Rebecca L.E. Miller , Lori J. Peterson , Jennifer A. Berger , Benjamin P. Warner
发明人: Eva R. Birnbaum , Rebecca L.E. Miller , Lori J. Peterson , Jennifer A. Berger , Benjamin P. Warner
CPC分类号: G01N33/6872 , G01N23/2076 , G01N23/223 , G01N33/502 , G01N2223/076
摘要: The present invention includes a method and apparatus for measuring the transport of analytes through a cell barrier.
摘要翻译: 本发明包括用于测量分析物通过细胞屏障的运输的方法和装置。
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公开(公告)号:US20150023467A1
公开(公告)日:2015-01-22
申请号:US14508322
申请日:2014-10-07
申请人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L.E. Miller
发明人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L.E. Miller
IPC分类号: G01N23/223 , G01N23/22
CPC分类号: G01N23/2202 , G01N23/2204 , G01N23/223 , G01N2223/074 , G01N2223/076 , G01N2223/309 , G01N2223/64 , G03B42/02
摘要: The present invention includes an apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. The apparatus comprises a plate having one or more holes passing through the plate. The holes are covered by a film on one side of the plate. The holes are less than 500 micrometers across in one dimension where the film covers the holes. The film is translucent to x-rays. The present invention also includes an apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. The apparatus comprises a plate having one or more holes passing through the plate. The holes are covered on one side of the plate by a detachable cover forming a water-tight seal against the plate. The cover is substantially free of the elements osmium, yttrium, iridium, phosphorus, zirconium, platinum, gold, niobium, mercury, thallium, molybdenum, sulfur, lead, bismuth, technetium, ruthenium, chlorine, rhodium, palladium, argon, silver, and thorium. The holes are less than about 500 micrometers across in one dimension where the cover covers the holes. The present invention also includes a method for preparing samples for measurement by x-ray fluorescence spectrometry. The method comprises providing a solution of with less than 10 micromolar solute and a volume of between about 2 microliters and about 2 milliliters. The solution is concentrated and analyzed using x-ray fluorescence spectrometry.
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公开(公告)号:US20090087919A1
公开(公告)日:2009-04-02
申请号:US12239459
申请日:2008-09-26
申请人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Lori J. Peterson-Court , Michael N. Harris , Rebecca L.E. Miller
发明人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Lori J. Peterson-Court , Michael N. Harris , Rebecca L.E. Miller
CPC分类号: C12Q1/485 , C12Q1/37 , G01N21/75 , G01N23/223 , G01N33/20 , G01N33/6842 , G01N2223/076 , G01N2333/91215 , G01N2333/96441 , Y10T436/17 , Y10T436/200833
摘要: The present invention includes a method for analyzing reactions. The method includes the steps of providing a solution of at least one acceptor chemical and at least one donor chemical. The donor chemical is capable of donating a chemical moiety to the acceptor chemical. The solution further includes at least one controller chemical that affects the reaction between the donor chemical and the acceptor chemical. The solution is then incubated so that a portion of the acceptor chemical reacts with the donor chemical to form an acceptor product. Unreacted donor chemical is separated from the acceptor product. The acceptor product or the donor chemical is then measured using X-ray fluorescence. Another aspect of the present invention includes a method for analyzing protein function. The method includes the steps of providing a solution of at least one acceptor chemical and at least one donor chemical. The donor chemical is capable of donating a chemical moiety to the acceptor chemical. The donor chemical includes a functional group selected from ester, anhydride, imide, acyl halide, and amide. The solution is then incubated so that a portion of the acceptor chemical reacts with the donor chemical to form an acceptor product. Unreacted donor chemical is separated from the acceptor product. The acceptor product or the donor chemical is then measured using X-ray fluorescence. Yet another aspect of the present invention includes a method for analyzing protein function. The method includes the steps of providing a solution of at least one acceptor chemical and at least one donor chemical. The solution is then incubated so that a portion of the acceptor chemical reacts with the donor chemical to form an acceptor product. Unreacted donor chemical is separated from the acceptor product. The acceptor product or the donor chemical is then measured using X-ray fluorescence. An additional analytical method is also used to measure either the acceptor product or the donor chemical.
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公开(公告)号:US08873707B2
公开(公告)日:2014-10-28
申请号:US13567613
申请日:2012-08-06
申请人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L. E. Miller
发明人: Eva R. Birnbaum , Benjamin P. Warner , Sharon M. Baldwin , Jennifer A. Berger , Rebecca L. E. Miller
IPC分类号: G01N1/28
CPC分类号: G01N23/2202 , G01N23/2204 , G01N23/223 , G01N2223/074 , G01N2223/076 , G01N2223/309 , G01N2223/64 , G03B42/02
摘要: An apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. A plate has one or more holes passing through the plate. The holes are covered by a film on one side of the plate. The holes are less than 500 micrometers across in one dimension where the film covers the holes. The film is translucent to x-rays.
摘要翻译: 通过X射线荧光光谱法制备用于测量的样品的装置。 板有一个或多个孔穿过板。 孔被板的一侧的薄膜覆盖。 在膜覆盖孔的一个维度上,孔小于500微米。 这部电影对于x射线是半透明的。
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