摘要:
The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.
摘要:
The invention relates to novel compounds of the general formula (I), with Het-2 being an optionally substituted bicyclic heteroaryl of the formula pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the use as ferroportin inhibitors, more particularly for the use in the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.
摘要:
Embodiments of the present invention relate to a method and system for providing automated directory assistance with minimum external or operator intervention. A directory listing request may be received from a user. The directory listing request may be recognized and a first search of a database may be conducted for the recognized directory listing request. If more than one match for the recognized directory listing request is found in the database, the user may be prompted to provide at least one of a street address and category information for the recognized directory listing request. A second search of the database may be conducted using at least one of the street address and the category information provided by the user. If a match for the recognized directory listing request is found, a directory listing may be output to the user.
摘要:
The invention concerns method and system for pre-processing entries in a directory listings. An automated attendant or automated directory listings assistant may use the pre-processed entries. A first directory listings including one or more fields may be received. The one or more fields may be populated with entries including one or more symbol strings. A second directory listings including one or more fields may be received. The one or more fields of the second directory listings may be populated with entries including one or symbol strings. Entries in the one or more fields of the first directory listings may be correlated with entries in the corresponding one or more fields of the second directory listings. Entries, in the one or more fields of the first directory listings, which do not correlate with entries in the corresponding one or more fields of the second directory listings may be identified. The identified entries may be processed using a rule set corresponding to the field in which the entry is located. Based on the rule set, a corresponding confidence level for the processed entries may be determined. The processed entries having the corresponding confidence level meeting or exceeding a threshold may be automatically modified. The automatically modified entries may be outputted for processing. In alternative embodiments of the present invention, the processed entries having the corresponding confidence level below the threshold may be marked for operator confirmation.