利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

12 条记录 (耗时 0.017 秒)

    Process for the preparation of 5-fluoro-2-nitrobenzoic acid
    1.
    发明授权
    Process for the preparation of 5-fluoro-2-nitrobenzoic acid 失效
    5-氟-2-硝基苯甲酸的制备方法

    公开(公告)号：US5756831A

    公开(公告)日：1998-05-26

    申请号：US667833

    申请日：1996-06-20

    申请人： Wolfram Kissener ,  Jurgen Kuprat ,  Herbert Emde ,  Klaus-Christian Paetz

    发明人： Wolfram Kissener ,  Jurgen Kuprat ,  Herbert Emde ,  Klaus-Christian Paetz

    IPC分类号： C07C201/08 ,  C07C201/16 ,  C07C205/58

    CPC分类号： C07C201/08

    摘要： 5-Fluoro-2-nitrobenzoic acid having low contents of 3-fluoro-2-nitro-benzoic acid is prepared in a simple manner by nitrating 3-fluorobenzoic acid in an anhydrous medium using an anhydrous nitrating acid and isolating and purifying 5-fluoro-2nitro-benzoic acid, by taking 7.5 to 15 parts by weight of water, based on 1 part by weight of 3-fluorobenzoic acid used, introducing the reaction mixture reacted to exhaustion into this volume of water taken, filtering off the precipitate formed and washing it with water.

    摘要翻译： 通过使用无水硝酸将氮氟酸在无水介质中硝化3-氟苯甲酸，分离纯化5-氟-2-硝基苯甲酸，得到3-氟-2-硝基 - 苯甲酸含量低的5-氟-2-硝基苯甲酸 -2-硝基 - 苯甲酸，通过使用7.5重量份水，以1重量份所用的3-氟苯甲酸为原料，将反应混合物反应至该体积的水中，滤出形成的沉淀物， 用水冲洗。

    Process for the preparation of isolated 3,4-diaminobenzenesulphonic acid
    3.
    发明授权
    Process for the preparation of isolated 3,4-diaminobenzenesulphonic acid 有权

    公开(公告)号：US06787666B2

    公开(公告)日：2004-09-07

    申请号：US10663827

    申请日：2003-09-16

    申请人： Günter Rauchschwalbe ,  Herbert Emde ,  Wolfram Kissener

    发明人： Günter Rauchschwalbe ,  Herbert Emde ,  Wolfram Kissener

    IPC分类号： C07C30900

    CPC分类号： C07C303/06 ,  C07C309/45

    摘要： Described herein is a process for the preparation of 3,4-diaminobenzenesulphonic acid, characterized in that 1,2-diaminobenzene is reacted with anhydrous sulphuric acid which optionally comprises SO3 in up to stoichiometric amount, at a temperature in the range from 100 to 160° C. with stirring for a reaction time of from 1 to 20 hours; water or ice is added to the reaction mixture, optionally with cooling, up to a sulphuric acid concentration in the range from 30 to 75% by weight, based on the total mixture; the 3,4-diaminobenzenesulphonic acid precipitated out of the reaction mixture is filtered off, optionally washed with dilute sulphuric acid and worked up.

    Process for separating mixtures of nitrobenzaldehyde isomers
    4.
    发明授权
    Process for separating mixtures of nitrobenzaldehyde isomers 失效
    分离硝基苯甲醛异构体混合物的方法

    公开(公告)号：US5567854A

    公开(公告)日：1996-10-22

    申请号：US532513

    申请日：1995-09-22

    申请人： Wolfram Kissener ,  Herbert Emde ,  Achim Fessenbecker

    发明人： Wolfram Kissener ,  Herbert Emde ,  Achim Fessenbecker

    IPC分类号： C07C201/16 ,  C07C205/44 ,  C07C45/82

    CPC分类号： C07C201/16

    摘要： 2- and 3-Nitrobenzaldehydes suitable for use as intermediates for the preparation of pharmaceuticals are obtained in a simple manner and without risk of uncontrolled decompositions by distilling mixtures of nitrobenzaldehyde isomers at bottom temperatures of at most 200.degree. C. in the presence of monomeric and/or polymeric aromatic amines and/or phenols and/or N- and S-containing phenothiazines.

    摘要翻译： 适用于制备药物的中间体的2-和3-硝基苯甲醛以简单的方式获得，没有不受控制的分解的风险，通过在最多200℃的底部温度下蒸馏硝基苯甲醛异构体的混合物，在单体和/ /或聚合芳族胺和/或酚类和/或含N-和S-的吩噻嗪。

    Process for preparing p-toluidine-2-sulphonic acid
    5.
    发明授权
    Process for preparing p-toluidine-2-sulphonic acid 失效
    对甲苯胺-2-磺酸的制备方法

    公开(公告)号：US4717514A

    公开(公告)日：1988-01-05

    申请号：US848357

    申请日：1986-04-04

    申请人： Heinz U. Blank ,  Herbert Emde ,  Rolf Schimpf

    发明人： Heinz U. Blank ,  Herbert Emde ,  Rolf Schimpf

    IPC分类号： C07C309/46 ,  C07C67/00 ,  C07C301/00 ,  C07C303/06 ,  C07C309/45 ,  C07C143/58

    CPC分类号： C07C309/45

    摘要： P-Toluidine-2-sulphonic acid (5-amino-2-methylbenzenesulphonic acid) is obtained in very pure form and virtually free of p-toluidine-3-sulphonic acid (2-amino-5-methylbenzenesulphonic acid) by reacting p-toluidine at 10.degree.-55.degree. C. with oleum in sulphuric acid. The molar ratio of SO.sub.3 to p-toluidine in this reaction is 1-3.0:1. The reaction mixture is worked up by pouring into water and filtering off the precipitated p-toluidine-2-sulphonic acid.

    摘要翻译： 以非常纯的形式获得对甲苯胺-2-磺酸（5-氨基-2-甲基苯磺酸），实际上不含对甲苯胺-3-磺酸（2-氨基-5-甲基苯磺酸） 甲苯胺在10 -55℃下与发烟硫酸在硫酸中反应。 该反应中SO 3与对甲苯胺的摩尔比为1-3.0:1。 将反应混合物倒入水中并滤出沉淀的对甲苯胺-2-磺酸。