公开(公告)号：US20160107982A1

公开(公告)日：2016-04-21

申请号：US14894822

申请日：2014-05-27

Applicant: M2I DEVELOPMENT

Inventor： Olivier GUERRET ,  Samuel DUFOUR ,  Hafid BELHADJ-TAHAR

IPC: C07C211/38 ,  C07C309/28 ,  A61K9/00

CPC classification number: C07C211/38 ,  A61K9/0019 ,  A61K51/0455 ,  C07C271/24 ,  C07C309/28 ,  C07C309/30 ,  C07C2603/74

Abstract: The present invention concerns novel chemical compounds corresponding to formulae (I) and (II): (I) (II) which, when marked with fluorine-18, can be used as markers of NMDA receptors for carrying out studies with a scanner.

Abstract translation: 本发明涉及对应于式（I）和（II）的新型化合物：（I）（II），当用氟-18标记时，其可用作用于用扫描仪进行研究的NMDA受体的标记。

公开(公告)号：US08900791B2

公开(公告)日：2014-12-02

申请号：US13071153

申请日：2011-03-24

Applicant: Tomotaka Tsuchimura ,  Koji Shirakawa ,  Toru Tsuchihashi ,  Hideaki Tsubaki

Inventor： Tomotaka Tsuchimura ,  Koji Shirakawa ,  Toru Tsuchihashi ,  Hideaki Tsubaki

IPC: G03F7/004 ,  G03F7/028 ,  C07C309/25 ,  C07C309/28 ,  C07C309/42 ,  C07C309/29 ,  C07C309/35 ,  C07C309/38 ,  C07C309/39 ,  C07C309/44 ,  C07C309/59 ,  C07C323/66 ,  C07C381/12 ,  C07D209/82 ,  C07D339/08 ,  G03F7/038 ,  G03F7/039

CPC classification number: C07C309/42 ,  C07C309/25 ,  C07C309/29 ,  C07C309/35 ,  C07C309/38 ,  C07C309/39 ,  C07C309/44 ,  C07C309/59 ,  C07C323/66 ,  C07C381/12 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/18 ,  C07C2602/28 ,  C07C2602/42 ,  C07C2602/44 ,  C07C2603/24 ,  C07C2603/28 ,  C07C2603/74 ,  C07D209/82 ,  C07D339/08 ,  G03F7/0045 ,  G03F7/0382 ,  G03F7/0392 ,  G03F7/0397 ,  Y10S430/122

Abstract: An actinic ray-sensitive or radiation-sensitive resin composition includes any of the compounds of general formula (I) below; wherein: Ar represents an aromatic ring that may have a substituent other than the -(A-B) groups; n is an integer of 1 or greater; A represents any one, or a combination of two or more members selected from a single bond, an alkylene group, —O—, —S—, —C(═O)—, —S(═O)—, —S(═O)2— and —OS(═O)2—, provided that —C(═O)O— is excluded; B represents a group containing a hydrocarbon group having 4 or more carbon atoms wherein either a tertiary or a quaternary carbon atom is contained, when n is 2 or greater, the two or more -(A-B) groups may be identical to or different from each other; and M+ represents an organic onium ion.

Abstract translation: 光化射线敏感或辐射敏感性树脂组合物包含下列通式（I）的任何化合物; 其中：Ar表示可以具有除 - （A-B）基团以外的取代基的芳香环; n是1或更大的整数; A表示选自单键，亚烷基，-O - ， - S - ， - C（= O） - ， - S（= O） - ， - S（ ≡O）2-和-OS（ΟO）2-，条件是不包括-C（= O）O-; B表示含有具有4个以上碳原子的烃基，其中含有叔或季碳原子的基团，当n为2以上时，两个以上（AB）基可以相同或不同， 其他; M +表示有机鎓离子。

公开(公告)号：US08173354B2

公开(公告)日：2012-05-08

申请号：US12831621

申请日：2010-07-07

Applicant: Youichi Ohsawa ,  Masaki Ohashi

Inventor： Youichi Ohsawa ,  Masaki Ohashi

IPC: G03F7/004 ,  G03F7/30 ,  C07C309/06 ,  C07C309/25 ,  C07C309/28

CPC classification number: G03F7/0045 ,  C07C381/12 ,  G03F7/0046 ,  G03F7/0382 ,  G03F7/0397 ,  G03F7/2041 ,  Y10S430/108 ,  Y10S430/111 ,  Y10S430/122

Abstract: A sulfonium salt having a triphenylsulfonium cation and a sulfite anion within the molecule is best suited as a photoacid generator in chemically amplified resist compositions. Upon exposure to high-energy radiation, the sulfonium salt generates a sulfonic acid, which facilitates efficient scission of acid labile groups in chemically amplified positive resist compositions. Because of substantial non-volatility under high vacuum conditions in the EB or EUV lithography, the risk of the exposure tool being contaminated is minimized.

Abstract translation: 在分子中具有三苯基锍阳离子和亚硫酸根阴离子的锍盐最适合作为化学增强抗蚀剂组合物中的光致酸产生剂。 在暴露于高能量辐射下，锍盐产生磺酸，这有助于化学放大的正性抗蚀剂组合物中酸不稳定基团的有效断裂。 由于在EB或EUV光刻中的高真空条件下具有显着的非挥发性，所以被污染的曝光工具的风险最小化。

公开(公告)号：US20070191481A1

公开(公告)日：2007-08-16

申请号：US10580135

申请日：2006-01-06

Applicant: Dong Lim ,  Eun Yang ,  Jac Ko ,  Kwang Choi ,  Yong Youn ,  Hea Suh ,  Chang Kim

Inventor： Dong Lim ,  Eun Yang ,  Jac Ko ,  Kwang Choi ,  Yong Youn ,  Hea Suh ,  Chang Kim

IPC: A61K31/185 ,  C07C309/20 ,  C07C309/28

CPC classification number: C07C211/63 ,  C07C211/29 ,  C07C309/04 ,  C07C309/05 ,  C07C309/19 ,  C07C309/29 ,  C07C309/30 ,  C07C2601/04 ,  C07C2602/42

Abstract: Disclosed is a novel sulphonic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Abstract translation: 公开了西布曲明的新型磺酸盐，具有良好的物理化学性质。 还公开了制备该化合物的方法和包含该化合物的药物组合物。

公开(公告)号：US6130335A

公开(公告)日：2000-10-10

申请号：US127378

申请日：1998-07-31

Applicant: Timothy C. Johnson ,  Robert J. Ehr ,  Timothy P. Martin ,  Mark A. Pobanz ,  John C. Van Heertum ,  Richard K. Mann

Inventor： Timothy C. Johnson ,  Robert J. Ehr ,  Timothy P. Martin ,  Mark A. Pobanz ,  John C. Van Heertum ,  Richard K. Mann

IPC: C07D487/04 ,  A01N43/90 ,  A01N47/24 ,  C07C309/23 ,  C07C309/28 ,  C07C309/86 ,  C07D213/71 ,  C07D213/74 ,  C07D213/79 ,  C07D333/66 ,  C07D405/12 ,  C07D471/04 ,  C07D213/60 ,  C07D213/62

CPC classification number: A01N43/90 ,  A01N47/24 ,  C07D333/66 ,  C07D471/04 ,  C07D487/04

Abstract: N-(Triazoloazinyl)arylsulfonamide compounds, such as 2,6-dimethoxy-N-(8-chloro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamide, 2-methoxy-4-(trifluoromethyl)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)pyridine-3-sulfonamide, and 2-methoxy-6-methoxycarbonyl-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-a]pyridin-2-yl)benzenesulfonamide were prepared from appropriately substituted 2-amino[1,2,4]triazolo[1,5-c]pyrimidine and 2-amino[1,2,4]triazolo[1,5-a]pyridine compounds and appropriately substituted benzenesulfonyl chloride and pyridine-3-sulfonyl chloride compounds. The compounds were found to be useful as herbicides.

Abstract translation: N-（三唑并嗪基）芳基磺酰胺化合物，例如2,6-二甲氧基-N-（8-氯-5-甲氧基[1,2,4]三唑并[1,5-c]嘧啶-2-基）苯磺酰胺，2 - 甲氧基-4-（三氟甲基）-N-（5,8-二甲氧基[1,2,4]三唑并[1,5-c]嘧啶-2-基）吡啶-3-磺酰胺和2-甲氧基-6- - 甲氧基羰基-N-（5,8-二甲氧基[1,2,4]三唑并[1,5-a]吡啶-2-基）苯磺酰胺由适当取代的2-氨基[1,2,4]三唑并[ 1,5-c]嘧啶和2-氨基[1,2,4]三唑并[1,5-a]吡啶化合物和适当取代的苯磺酰氯和吡啶-3-磺酰氯化合物。 发现这些化合物可用作除草剂。

公开(公告)号：US6127568A

公开(公告)日：2000-10-03

申请号：US136143

申请日：1998-08-18

Applicant: Herbert Bayer ,  Hubert Sauter ,  Ruth Muller ,  Wassilios Grammenos ,  Albrecht Harreus ,  Reinhard Kirstgen ,  Franz Rohl ,  Eberhard Ammermann ,  Gisela Lorenz

Inventor： Herbert Bayer ,  Hubert Sauter ,  Ruth Muller ,  Wassilios Grammenos ,  Albrecht Harreus ,  Reinhard Kirstgen ,  Franz Rohl ,  Eberhard Ammermann ,  Gisela Lorenz

IPC: C07D249/08 ,  A01N20060101 ,  A01N37/00 ,  A01N37/36 ,  A01N37/44 ,  A01N37/50 ,  A01N41/10 ,  A01N43/00 ,  A01N43/08 ,  A01N43/10 ,  A01N43/12 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/60 ,  A01N43/66 ,  A01N43/707 ,  A01N43/72 ,  A01N43/76 ,  A01N43/78 ,  A01N43/80 ,  A01N43/824 ,  A01N43/836 ,  A01N43/88 ,  A01N47/02 ,  A01P3/00 ,  A01P7/04 ,  C07C20060101 ,  C07C205/04 ,  C07C249/08 ,  C07C251/34 ,  C07C251/36 ,  C07C251/38 ,  C07C251/48 ,  C07C251/50 ,  C07C251/52 ,  C07C251/54 ,  C07C251/56 ,  C07C251/60 ,  C07C255/07 ,  C07C255/12 ,  C07C255/62 ,  C07C255/64 ,  C07C259/06 ,  C07C259/14 ,  C07C309/04 ,  C07C309/28 ,  C07C317/18 ,  C07C317/22 ,  C07C317/26 ,  C07C317/44 ,  C07C323/12 ,  C07C323/19 ,  C07C323/23 ,  C07C325/00 ,  C07C327/38 ,  C07C327/42 ,  C07C327/48 ,  C07C327/58 ,  C07D207/32 ,  C07D207/323 ,  C07D207/333 ,  C07D207/36 ,  C07D211/72 ,  C07D211/88 ,  C07D213/30 ,  C07D213/50 ,  C07D213/53 ,  C07D213/61 ,  C07D213/64 ,  C07D213/65 ,  C07D213/68 ,  C07D213/71 ,  C07D213/79 ,  C07D213/80 ,  C07D215/20 ,  C07D215/22 ,  C07D231/12 ,  C07D231/20 ,  C07D231/22 ,  C07D233/61 ,  C07D233/64 ,  C07D237/08 ,  C07D237/12 ,  C07D237/14 ,  C07D239/26 ,  C07D239/28 ,  C07D239/30 ,  C07D239/34 ,  C07D239/36 ,  C07D239/38 ,  C07D239/74 ,  C07D241/12 ,  C07D241/16 ,  C07D241/18 ,  C07D241/44 ,  C07D251/16 ,  C07D251/26 ,  C07D251/30 ,  C07D261/06 ,  C07D261/08 ,  C07D261/10 ,  C07D261/12 ,  C07D263/32 ,  C07D263/34 ,  C07D263/46 ,  C07D271/06 ,  C07D271/10 ,  C07D275/02 ,  C07D277/20 ,  C07D277/24 ,  C07D277/28 ,  C07D277/32 ,  C07D277/34 ,  C07D277/36 ,  C07D285/08 ,  C07D285/12 ,  C07D307/12 ,  C07D307/36 ,  C07D307/42 ,  C07D307/52 ,  C07D307/56 ,  C07D307/58 ,  C07D333/16 ,  C07D333/22 ,  C07D333/28 ,  C07D333/32

CPC classification number: C07D207/333 ,  A01N37/36 ,  A01N37/50 ,  A01N43/08 ,  A01N43/36 ,  A01N43/40 ,  A01N43/54 ,  A01N43/76 ,  A01N43/78 ,  A01N43/80 ,  A01N43/88 ,  C07C249/08 ,  C07C251/38 ,  C07C251/48 ,  C07C251/60 ,  C07C327/58 ,  C07D213/53 ,  C07D213/64 ,  C07D239/34 ,  C07D239/36 ,  C07D261/08 ,  C07D261/10 ,  C07D263/32 ,  C07D271/06 ,  C07D277/24 ,  C07D307/12 ,  C07C2101/02 ,  C07C2101/04 ,  C07C2101/08 ,  C07C2101/14

Abstract: Phenylacetic acid derivatives of the formula I ##STR1## where the substituents and the index have the following meanings: X is NOCH.sub.3, CHOCH.sub.3, CHCH.sub.3 and [sic] CHCH.sub.2 CH.sub.3 ;R.sup.1 is hydrogen and [sic] alkyl;R.sup.2 is cyano, nitro, trifluoromethyl, halogen, alkyl and [sic] alkoxy;m is 0, 1 or 2, it being possible for the R.sup.2 radicals to be different if m is 2;R.sup.3 is hydrogen, cyano, nitro, hydroxyl, amino, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, alkylamino or dialkylamino;R.sup.4 and R.sup.5 are as defined in the specification.

Abstract translation: 取代基和指数具有以下含义的式I的苯乙酸衍生物：X为NOCH 3，CHOCH 3，CHCH 3和[sic] CHCH 2 CH 3; R1是氢和[sic]烷基; R2是氰基，硝基，三氟甲基，卤素，烷基和[sic]烷氧基; m为0,1或2，如果m为2，则R2基团可能不同; R3是氢，氰基，硝基，羟基，氨基，卤素，烷基，卤代烷基，烷氧基，卤代烷氧基，烷硫基，烷基氨基或二烷基氨基; R4和R5如说明书中所定义。

公开(公告)号：US5965490A

公开(公告)日：1999-10-12

申请号：US127384

申请日：1998-07-31

Applicant: Timothy C. Johnson ,  Robert J. Ehr ,  William A. Kleschick ,  Mark A. Pobanz ,  Richard K. Mann ,  John C. Van Heertum

Inventor： Timothy C. Johnson ,  Robert J. Ehr ,  William A. Kleschick ,  Mark A. Pobanz ,  Richard K. Mann ,  John C. Van Heertum

IPC: C07D487/04 ,  A01N43/90 ,  A01N47/24 ,  C07C309/23 ,  C07C309/28 ,  C07C309/86 ,  C07D213/71 ,  C07D213/74 ,  C07D213/79 ,  C07D333/66 ,  C07D405/12 ,  C07D471/04

CPC classification number: A01N43/90 ,  A01N47/24 ,  C07D333/66 ,  C07D471/04 ,  C07D487/04

Abstract: N-(Triazoloazinyl)arylsulfonamide compounds, such as 2,6-dimethoxy-N-(8-chloro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamide, 2-methoxy-4-(trifluoromethyl)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)pyridine-3-sulfonamide, and 2-methoxy-6-methoxycarbonyl-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-a]pyridin-2-yl)benzenesulfonamide were prepared from appropriately substituted 2-amino[1,2,4]triazolo[1,5-c]pyrimidine and 2-amino[1,2,4]triazolo[1,5-a]pyridine compounds and appropriately substituted benzenesulfonyl chloride and pyridine-3-sulfonyl chloride compounds. The compounds were found to be useful as herbicides.

Abstract translation: N-（三唑并嗪基）芳基磺酰胺化合物，例如2,6-二甲氧基-N-（8-氯-5-甲氧基[1,2,4]三唑并[1,5-c]嘧啶-2-基）苯磺酰胺，2 - 甲氧基-4-（三氟甲基）-N-（5,8-二甲氧基[1,2,4]三唑并[1,5-c]嘧啶-2-基）吡啶-3-磺酰胺和2-甲氧基-6- - 甲氧基羰基-N-（5,8-二甲氧基[1,2,4]三唑并[1,5-a]吡啶-2-基）苯磺酰胺由适当取代的2-氨基[1,2,4]三唑并[ 1,5-c]嘧啶和2-氨基[1,2,4]三唑并[1,5-a]吡啶化合物和适当取代的苯磺酰氯和吡啶-3-磺酰氯化合物。 发现这些化合物可用作除草剂。

公开(公告)号：US5741905A

公开(公告)日：1998-04-21

申请号：US471816

申请日：1995-06-06

Applicant: Jean-Pierre Bacher ,  Werner Kaufmann ,  Dieter Reinehr

Inventor： Jean-Pierre Bacher ,  Werner Kaufmann ,  Dieter Reinehr

IPC: C07C235/20 ,  C07C309/28 ,  C07C317/22 ,  C07D249/20 ,  C07D251/16 ,  C07D251/24 ,  C07D251/42 ,  C07D251/44 ,  C07D251/50 ,  C07D251/70 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C09K3/00 ,  D06M13/02 ,  D06M13/12 ,  D06M13/152 ,  D06M13/322 ,  D06M13/35 ,  D06M13/352 ,  D06M13/355 ,  D06M13/358 ,  D06M101/00 ,  D06M101/02 ,  D06M101/06 ,  D06M101/08 ,  D06M101/10 ,  D06M101/16 ,  D06M101/30 ,  D06M101/32 ,  D06M101/34 ,  D06P1/642 ,  D06P1/651 ,  C07D251/38 ,  C07D251/30 ,  C07D251/48

CPC classification number: C07D403/12 ,  C07C235/20 ,  C07D249/20 ,  C07D251/24 ,  C07D251/42 ,  C07D251/44 ,  C07D251/50 ,  C07D251/70 ,  C07D403/14 ,  C07D405/12 ,  D06M13/12 ,  D06M13/352 ,  D06M13/358 ,  D06P1/6426 ,  D06P1/65112 ,  D06M2200/25 ,  Y10T442/2762

Abstract: New compounds having the formula ##STR1## in which m is 1 or 2; when m is 1, A is a residue selected from those of the formulae ##STR2## and, when m is 2, A is a residue of the formula ##STR3## B is --O--, --NH-- or --SO.sub.2 --, and D is as defined herein, are useful as ultraviolet absorbing agents (UVAs) and a method of improving the sun protection factor of textile fibre material by treating the material with the new compounds.

Abstract translation: 具有式A（BD）m（1）的新化合物，其中m为1或2; 当m为1时，A为选自下式的残基：（2）式（5）B为-O - ， - NH-或-SO 2 - ，并且D如本文所定义， 可用作紫外线吸收剂（UVA）和通过用新化合物处理材料来改善纺织纤维材料的防晒系数的方法。

公开(公告)号：US4867916A

公开(公告)日：1989-09-19

申请号：US128109

申请日：1987-12-03

Applicant: William R. Sanderson ,  John P. Sankey

Inventor： William R. Sanderson ,  John P. Sankey

IPC: C07C69/76 ,  C07C303/00 ,  C07C309/28 ,  C07C309/41 ,  C07C309/42

CPC classification number: C07C309/00

Abstract: Phenol sulphonate esters can be made in a known process by reacting an alkali metal phenol sulphonate salt with an acyl halide in a hydrocarbon solvent at elevated temperatures, but the use of anhydrous materials were strongly advocated because any residual water hydrolyses the acyl chloride in a competitive reaction. However, it becomes particularly difficult and expensive to dehydrate phenol sulphonate salts below about 2% w/w water on a commercial scale and the product obtained by reaction from such partly dehydrated salts can be comparatively impure or reduced in yield. Consequently, changes to the process such as omitting the solvent or using a different acylating agent have been proposed, but these alternatives introduce their own respective manufacturing problems such as entrainment of viscous acyl chloride and anhydride in the product or introduction of a cumbersome and hence expensive recovery process involving an extra distillation step amongst others.The present invention provides a surprisingly convenient modification to the known process in which the esterification and product separation steps are incorporated into a cycle together with an acyl halide preparation step in which residual carboxylic acid and anhydride in solution after product separation is preferably augmented with a replenishing amount of carboxylic acid and then reacted with thiony halide. The resultant ester is readily separable and is obtained in comparatively good yield.

公开(公告)号：US4788011A

公开(公告)日：1988-11-29

申请号：US880623

申请日：1986-07-01

Applicant: Roland Busse ,  Herbert Emde ,  Friedrich Durholz ,  Dietmar Mayer ,  Dorde Jovcic

Inventor： Roland Busse ,  Herbert Emde ,  Friedrich Durholz ,  Dietmar Mayer ,  Dorde Jovcic

IPC: B01F5/18 ,  B01D1/18 ,  B01F5/20 ,  B01J14/00 ,  B01J19/00 ,  B01J19/26 ,  C07B31/00 ,  C07B41/00 ,  C07B61/00 ,  C07B63/00 ,  C07C37/04 ,  C07C39/15 ,  C07C67/00 ,  C07C301/00 ,  C07C303/00 ,  C07C303/02 ,  C07C303/06 ,  C07C303/32 ,  C07C309/28 ,  C07C309/32 ,  C07C309/47 ,  C07C309/50 ,  C07C309/58 ,  C07C143/52 ,  C07C143/24 ,  C07C143/56

CPC classification number: C07C309/00 ,  B01J14/00 ,  B01J19/26 ,  B01J2219/00058 ,  B01J2219/00065

Abstract: Reactions of liquid starting substances to give chemical compounds in which these chemical compounds are obtained as solids can be carried out by spraying the liquid starting substances from separate nozzles such that the liquid starting substances are mixed in the spray cones, which penetrate one another, and thereby react.

Abstract translation: 可以通过将液体起始物质从单独的喷嘴喷射，使得液体起始物质彼此渗透的喷雾锥体混合，从而得到液体起始物质得到其中获得这些化合物作为固体的化合物的反应， 从而作出反应。