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    DRUG SELECTION FOR CANCER THERAPY BY PROFILING SIGNAL TRANSDUCTION PROTEINS IN ASCITES OR PLEURAL EFFLUX SAMPLES
    8.
    发明申请
    DRUG SELECTION FOR CANCER THERAPY BY PROFILING SIGNAL TRANSDUCTION PROTEINS IN ASCITES OR PLEURAL EFFLUX SAMPLES 审中-公开
    通过在ASCIS或PLEURAL EFFLUX样品中分配信号转导蛋白来进行癌症治疗的药物选择

    公开(公告)号：US20120270745A1

    公开(公告)日：2012-10-25

    申请号：US13354257

    申请日：2012-01-19

    申请人： Sharat Singh ,  Phillip Kim ,  Xinjun Liu ,  Belen Ybarrondo ,  Limin Liu

    发明人： Sharat Singh ,  Phillip Kim ,  Xinjun Liu ,  Belen Ybarrondo ,  Limin Liu

    IPC分类号： C40B30/04

    CPC分类号： G01N33/5011 ,  G01N33/5041

    摘要： The present invention provides methods for selecting a suitable anticancer therapy and for identifying and predicting response for the treatment of a gastric cancer by determining the expression level and/or activation level of one or more analytes in a cell such as a cancer cell from an ascites sample. The present invention also provides methods for selecting a suitable anticancer therapy and for identifying and predicting response for the treatment of a lung cancer such as a non-small cell lung cancer by determining the expression level and/or activation level of one or more analytes in a cell such as a cancer cell from a pleural efflux sample.

    摘要翻译： 本发明提供了选择合适的抗癌疗法以及通过测定细胞如癌症细胞中的一种或多种分析物的表达水平和/或活化水平来鉴定和预测胃癌治疗反应的方法 样品。 本发明还提供了选择合适的抗癌疗法以及通过确定一种或多种分析物的表达水平和/或活化水平来鉴定和预测用于治疗肺癌如非小细胞肺癌的反应的方法 来自胸膜外排样品的细胞例如癌细胞。