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1.发明授权Luma-chroma coding with one common or three distinct spatial predictors 有权Luma-chroma编码与一个共同或三个不同的空间预测器公开(公告)号：US08761251B2
公开(公告)日：2014-06-24
申请号：US11918027
申请日：2006-03-16
Applicant: Haoping Yu , Limin Liu
Inventor： Haoping Yu , Limin Liu
IPC: H04N7/12
CPC classification number: H04N19/61 , H04N19/103 , H04N19/105 , H04N19/107 , H04N19/11 , H04N19/122 , H04N19/157 , H04N19/176 , H04N19/186 , H04N19/46 , H04N19/50 , H04N19/593 , H04N19/70 , H04N19/85
Abstract: There are provided video encoders, video decoders, and corresponding methods. A video encoder for encoding video signal data for an image block includes an encoder for encoding all color components of the video signal data using a common predictor.
Abstract translation: 提供视频编码器，视频解码器和相应的方法。 用于对图像块的视频信号数据进行编码的视频编码器包括用于使用公共预测器对视频信号数据的所有颜色分量进行编码的编码器。
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2.发明授权Electrochemical biosensor for direct determination of percentage of glycated hemoglobin 失效用于直接测定糖化血红蛋白百分比的电化学生物传感器公开(公告)号：US08673646B2
公开(公告)日：2014-03-18
申请号：US12465143
申请日：2009-05-13
Applicant: Chong-Sheng Yuan , Neal K. Blue , Abhijit Datta , Limin Liu , Lei Fang
Inventor： Chong-Sheng Yuan , Neal K. Blue , Abhijit Datta , Limin Liu , Lei Fang
IPC: G01N33/72
CPC classification number: G01N33/723 , C12Q1/005 , G01N33/5438 , G01N2333/906
Abstract: The invention provides electrochemical biosensors for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in blood samples. The invention provides methods for using the electrochemical biosensors.
Abstract translation: 本发明提供用于直接测定血液样品中糖化血红蛋白百分比的电化学生物传感器，而不需要分离测量血液样品中的总血红蛋白含量。 本发明提供了使用电化学生物传感器的方法。
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3.发明申请公开(公告)号：US20130196342A1
公开(公告)日：2013-08-01
申请号：US13094091
申请日：2011-04-26
Applicant: Jonathan S. Stamler , Limin Liu
Inventor： Jonathan S. Stamler , Limin Liu
IPC: G01N33/573
CPC classification number: G01N33/573 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/035 , A61K31/155 , A61K31/41 , A61K38/44 , C12N9/0008 , C12N15/8509 , C12Q1/26 , C12Y102/01046 , G01N2333/90212 , G01N2800/00 , A61K2300/00
Abstract: Disclosed herein are methods and compositions for modulating the levels and/or activity of S-nitrosoglutathione reductase (GSNOR) in vivo or in vitro. Specifically disclosed are GSNOR deletion constructs, host cells and non-human mammals comprising GSNOR deletions, and methods of screening employing GSNOR deletion mutants. Also specifically disclosed are reagents and procedures for measuring, monitoring, or altering GSNOR levels or activity (as well as nitric oxide and S-nitrosothiol levels) in connection with various medical conditions.
Abstract translation: 本文公开了用于在体内或体外调节S-亚硝基谷胱甘肽还原酶（GSNOR）的水平和/或活性的方法和组合物。 具体公开的是GSNOR缺失构建体，宿主细胞和包含GSNOR缺失的非人哺乳动物，以及使用GSNOR缺失突变体进行筛选的方法。 还具体公开了用于测量，监测或改变与各种医学状况有关的GSNOR水平或活性（以及一氧化氮和S-亚硝基硫醇水平）的试剂和程序。
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公开(公告)号：US20120245116A1
公开(公告)日：2012-09-27
申请号：US13491752
申请日：2012-06-08
Applicant: Jonathan S. Stamler , Limin Liu , Alfred Hausladen , Raphael Nudelman
Inventor： Jonathan S. Stamler , Limin Liu , Alfred Hausladen , Raphael Nudelman
IPC: A61K31/7056 , A61K31/197 , A61K31/343
CPC classification number: A61K38/063 , A61K31/365 , A61K31/7056 , Y10S514/824
Abstract: Patients needing NO donor therapy or inhibition of pathologically proliferating cells or increased NO bioactivity are treated with a therapeutically effective amount of an inhibitor of glutathione-dependent formaldehyde dehydrogenase.
Abstract translation: 需要NO供体治疗或抑制病理增殖细胞或增加NO生物活性的患者用治疗有效量的谷胱甘肽依赖性甲醛脱氢酶抑制剂治疗。
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5.发明授权公开(公告)号：US08163499B2
公开(公告)日：2012-04-24
申请号：US12511017
申请日：2009-07-28
Applicant: Sharat Singh , Jeanne Harvey , Phillip Kim , Xinjun Liu , Limin Liu , Robert Barham , Bruce Neri
Inventor： Sharat Singh , Jeanne Harvey , Phillip Kim , Xinjun Liu , Limin Liu , Robert Barham , Bruce Neri
IPC: G01N33/53 , G01N33/58 , G01N33/68 , G01N33/545 , G01N33/574
CPC classification number: G01N33/57415 , G01N33/5011 , G01N2800/52 , G01N2800/60
Abstract: The present invention provides compositions and methods for detecting the activation states of components of signal transduction pathways in tumor cells. Information on the activation states of components of signal transduction pathways derived from use of the invention can be used for cancer diagnosis, prognosis, and in the design of cancer treatments.
Abstract translation: 本发明提供用于检测肿瘤细胞中信号转导途径的组分的激活状态的组合物和方法。 关于使用本发明的信号转导途径的组分的激活状态的信息可用于癌症诊断，预后和癌症治疗的设计。
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Patent Agency Ranking
公开(公告)号：US20110189712A1
公开(公告)日：2011-08-04
申请号：US12944586
申请日：2010-11-11
Applicant: Chong-Sheng Yuan , Abhijit Datta , Limin Liu
Inventor： Chong-Sheng Yuan , Abhijit Datta , Limin Liu
IPC: C12Q1/37
CPC classification number: G01N33/723 , Y10T436/104998 , Y10T436/105831 , Y10T436/107497 , Y10T436/25375
Abstract: The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in blood samples. The methods utilizes one or two different types of oxidizing agents which selectively oxidize low-molecular weight reducing substances and high-molecular weight (mainly hemoglobin) reducing substances in blood samples, coupled with enzymatic reactions catalyzed by proteases, fructosyl amino acid oxidase, and peroxidase. The invention provides kits for performing the methods of the invention.
Abstract translation: 本发明提供用于直接测定血液样品中糖化血红蛋白百分比的酶法，而不需要分离测量血液样品中的总血红蛋白含量。 该方法使用一种或两种不同类型的氧化剂，其选择性地氧化血液样品中的低分子量还原物质和高分子量（主要是血红蛋白）还原物质，加上由蛋白酶，果糖基氨基酸氧化酶和过氧化物酶催化的酶反应 。 本发明提供了用于实施本发明方法的试剂盒。
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7.发明申请公开(公告)号：US20100167945A1
公开(公告)日：2010-07-01
申请号：US12511017
申请日：2009-07-28
Applicant: Sharat Singh , Jeanne Harvey , Phillip Kim , Xinjun Liu , Limin Liu , Robert Barham , Bruce Neri
Inventor： Sharat Singh , Jeanne Harvey , Phillip Kim , Xinjun Liu , Limin Liu , Robert Barham , Bruce Neri
IPC: C40B30/04 , C12Q1/26 , G01N33/566 , C12Q1/28 , C40B40/10
CPC classification number: G01N33/57415 , G01N33/5011 , G01N2800/52 , G01N2800/60
Abstract: The present invention provides compositions and methods for detecting the activation states of components of signal transduction pathways in tumor cells. Information on the activation states of components of signal transduction pathways derived from use of the invention can be used for cancer diagnosis, prognosis, and in the design of cancer treatments.
Abstract translation: 本发明提供用于检测肿瘤细胞中信号转导途径的组分的激活状态的组合物和方法。 关于使用本发明的信号转导途径的组分的激活状态的信息可用于癌症诊断，预后和癌症治疗的设计。
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8.发明申请公开(公告)号：US20090052527A1
公开(公告)日：2009-02-26
申请号：US11918027
申请日：2006-03-16
Applicant: Haoping Yu , Limin Liu
Inventor： Haoping Yu , Limin Liu
IPC: H04N7/26
CPC classification number: H04N19/61 , H04N19/103 , H04N19/105 , H04N19/107 , H04N19/11 , H04N19/122 , H04N19/157 , H04N19/176 , H04N19/186 , H04N19/46 , H04N19/50 , H04N19/593 , H04N19/70 , H04N19/85
Abstract: There are provided video encoders, video decoders, and corresponding methods. A video encoder for encoding video signal data for an image block includes an encoder for encoding all color components of the video signal data using a common predictor.
Abstract translation: 提供视频编码器，视频解码器和相应的方法。 用于对图像块的视频信号数据进行编码的视频编码器包括用于使用公共预测器对视频信号数据的所有颜色分量进行编码的编码器。
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公开(公告)号：US20080299597A1
公开(公告)日：2008-12-04
申请号：US12120122
申请日：2008-05-13
Applicant: Chong-Sheng YUAN , Abhijit Datta , Limin Liu
Inventor： Chong-Sheng YUAN , Abhijit Datta , Limin Liu
IPC: C12Q1/37
CPC classification number: C12Q1/28 , G01N33/723
Abstract: The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in blood samples. The methods utilizes one or two different types of oxidizing agents which selectively oxidize low-molecular weight reducing substances and high-molecular weight (mainly hemoglobin) reducing substances in blood samples, coupled with enzymatic reactions catalyzed by proteases, fructosyl amino acid oxidase. The amount of hydrogen peroxide generated in the reaction is measured for determination of percentage of glycated hemoglobin in blood samples. The invention provides kits for performing the methods of the invention.
Abstract translation: 本发明提供用于直接测定血液样品中糖化血红蛋白百分比的酶法，而不需要分离测量血液样品中的总血红蛋白含量。 该方法使用一种或两种不同类型的氧化剂，其选择性地氧化血液样品中的低分子量还原物质和高分子量（主要是血红蛋白）还原物质，加上由蛋白酶，果糖基氨基酸氧化酶催化的酶反应。 测定反应中产生的过氧化氢的量，以测定血液样品中糖化血红蛋白的百分比。 本发明提供了用于实施本发明方法的试剂盒。
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公开(公告)号：US20070111949A1
公开(公告)日：2007-05-17
申请号：US11648406
申请日：2006-12-29
Applicant: Jonathan Stamler , Limin Liu , Alfred Hausladen , Raphael Nudelman
Inventor： Jonathan Stamler , Limin Liu , Alfred Hausladen , Raphael Nudelman
IPC: A61K38/05 , A61K31/365
CPC classification number: A61K38/063 , A61K31/365 , A61K31/7056 , Y10S514/824
Abstract: Patients needing NO donor therapy or inhibition of pathologically proliferating cells or increased NO bioactivity are treated with a therapeutically effective amount of an inhibitor of glutathione-dependent formaldehyde dehydrogenase.
Abstract translation: 需要NO供体治疗或抑制病理增殖细胞或增加NO生物活性的患者用治疗有效量的谷胱甘肽依赖性甲醛脱氢酶抑制剂治疗。
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