公开(公告)号：US08722634B2

公开(公告)日：2014-05-13

申请号：US12865843

申请日：2009-01-14

申请人： Yang Ye ,  Minjia Tan ,  Changqiang Ke ,  Tong Chen ,  Xiqiang Li ,  Edward Kraegen ,  Jiming Ye ,  David James ,  Gregory Cooney

发明人： Yang Ye ,  Minjia Tan ,  Changqiang Ke ,  Tong Chen ,  Xiqiang Li ,  Edward Kraegen ,  Jiming Ye ,  David James ,  Gregory Cooney

IPC分类号： A61K31/70

CPC分类号： A61K31/575 ,  A61K31/704

摘要： The present invention disclosed a medical use of cucurbitane triterpenoids represented by the following formula and isolated from Momordica charantia L. of Cucurbitaceae family in the preparation of medications for prevention and treatment of diabetes and obesity. The above cucurbitane triterpenoids may be acted as a glucose uptake stimulator, an agonist for the translocation of glucose transporter 4 (GLUT4) to the cell membrane, and an activator of adenosine monophosphate-activated protein kinase (AMPK). They may have potential for the prevention and treatment of diabetes and obesity.

摘要翻译： 本发明公开了葫芦科三萜类化合物的医学用途，其由葫芦科科的苦瓜属分离，用于制备预防和治疗糖尿病和肥胖症的药物。 上述葫芦巴三萜类化合物可以作为葡萄糖吸收刺激剂，用于将葡萄糖转运蛋白4（GLUT4）转运至细胞膜的激动剂和腺苷一磷酸酯活化蛋白激酶（AMPK）的激活剂。 他们可能有预防和治疗糖尿病和肥胖的潜力。

公开(公告)号：US20110152208A1

公开(公告)日：2011-06-23

申请号：US12865843

申请日：2009-01-14

申请人： Yang Ye ,  David E. James ,  Minjia Tan ,  Gregory J. Cooney ,  Changqiang Ke ,  Edward W. Kraegen ,  Tong Chen ,  Jiming Ye ,  Xiqiang Li

发明人： Yang Ye ,  David E. James ,  Minjia Tan ,  Gregory J. Cooney ,  Changqiang Ke ,  Edward W. Kraegen ,  Tong Chen ,  Jiming Ye ,  Xiqiang Li

IPC分类号： A61K31/7032 ,  C07J9/00 ,  C07H15/00 ,  A61K31/575 ,  A61P3/04 ,  A61P3/10

CPC分类号： A61K31/575 ,  A61K31/704

摘要： The present invention disclosed a medical use of cucurbitane triterpenoids represented by the following formula and isolated from Momordica charantia L. of Cucurbitaceae family in the preparation of medications for prevention and treatment of diabetes and obesity. The above cucurbitane triterpenoids may be acted as a glucose uptake stimulator, an agonist for the translocation of glucose transporter 4(GLUT4) to the cell membrane, and an activator of adenosine monophosphate-activated protein kinase (AMPK). They may have potential for the prevention and treatment of diabetes and obesity.

摘要翻译： 本发明公开了葫芦科三萜类化合物的医学用途，其由葫芦科科的苦瓜属分离，用于制备预防和治疗糖尿病和肥胖症的药物。 上述葫芦巴三萜类化合物可以作为葡萄糖吸收刺激剂，用于将葡萄糖转运蛋白4（GLUT4）转运至细胞膜的激动剂和腺苷一磷酸酯活化蛋白激酶（AMPK）的激活剂。 他们可能有预防和治疗糖尿病和肥胖的潜力。

公开(公告)号：US08275649B2

公开(公告)日：2012-09-25

申请号：US12562588

申请日：2009-09-18

申请人： Yu Zheng ,  Yang Ye ,  Xing Xie

发明人： Yu Zheng ,  Yang Ye ,  Xing Xie

IPC分类号： G06Q30/00

CPC分类号： G06Q30/02 ,  G06Q30/0201 ,  G06Q30/0205 ,  G06Q30/0261

摘要： Techniques for providing mining life pattern are described. This disclosure describes mining a life pattern of an individual, for example, by identifying places visited during the individual's daily activities. Mining the individual life pattern includes collecting location data for the individual and predicting behaviors and preferences of the individual based at least in part on a location history. The location history of the individual is represented with a sequence of geographical regions that have been visited by the individual with corresponding arrival and departure times for each region. Once the life pattern is predicted from the location history, information is recommended to the individual based at least in part on the life pattern.

摘要翻译： 描述了提供采矿寿命模式的技术。 本公开内容描述了挖掘个人的生活方式，例如，通过识别个人日常活动期间访问的地点。 挖掘个人生活方式包括至少部分地基于位置历史来收集个人的位置数据并预测个体的行为和偏好。 个人的位置历史由具有每个区域的对应的到达和离开时间的个人访问的地理区域的序列表示。 一旦根据位置历史预测生活方式，至少部分地基于生活方式向个人推荐信息。

公开(公告)号：US07868621B2

公开(公告)日：2011-01-11

申请号：US12041941

申请日：2008-03-04

申请人： Zhenning Liu ,  Randy J. Fuller ,  Wenjiang Yu ,  Yang Ye ,  Guangjun G. Liu

发明人： Zhenning Liu ,  Randy J. Fuller ,  Wenjiang Yu ,  Yang Ye ,  Guangjun G. Liu

IPC分类号： G01R31/08 ,  G01R31/02

CPC分类号： G01R31/008 ,  G01R31/025 ,  G01R31/086 ,  G01R31/11 ,  H04B3/546 ,  H04B2203/5445 ,  H04B2203/5458 ,  H04B2203/5495

摘要： A power line communication-based aircraft power distribution system may allow for both power line communication (PLC) technology and spread spectrum time domain reflectometry (SSTDR) technology to be utilized in aircraft power distribution systems to achieve key maintenance functions. Unlike conventional power distribution systems, which may, for example, use only SSTDR for fault detection, the present invention includes a hardware platform that may allow both the PLC and the SSTDR to be utilized in aircraft power distribution systems to achieve key maintenance functions, such as real time wire fault location, and cost and weight savings. Further, unlike conventional power distribution systems, which may only detect and locate damage in feeder conductor wire sections before the power is applied to the load, the power distribution system of the present invention may permit real time wire fault location.

摘要翻译： 基于电力线通信的飞机配电系统可以允许在飞机配电系统中利用电力线通信（PLC）技术和扩频时域反射计（SSTDR）技术来实现关键维护功能。 与常规配电系统不同，传统配电系统可能例如仅使用SSTDR进行故障检测，本发明包括硬件平台，其可以允许PLC和SSTDR在飞机配电系统中使用以实现关键维护功能，例如 作为实时线路故障定位，并节省成本和重量。 此外，与在功率施加到负载之前只能检测和定位馈线导线部分中的损坏的常规配电系统不同，本发明的配电系统可以允许实时线路故障定位。

公开(公告)号：US07808219B2

公开(公告)日：2010-10-05

申请号：US11945035

申请日：2007-11-26

申请人： Yang Ye ,  Wenjiang Yu ,  Yuanli Kathy Kang ,  Zhenning Z. Liu ,  Randy J. Fuller

发明人： Yang Ye ,  Wenjiang Yu ,  Yuanli Kathy Kang ,  Zhenning Z. Liu ,  Randy J. Fuller

IPC分类号： G05F1/613 ,  H02M7/00

CPC分类号： H02M7/2176 ,  H02M2001/007

摘要： An AC/DC power converter has, as its first stage, a capacitor divider and rectifier and, as the second stage, a switch mode power supply. This configuration may be suitable for low power low voltage aerospace applications. The benefits of the circuit may include small reactive component size; near sinusoidal input current, low EMI emissions resulting from low inrush current; intrinsic current limiting that may eliminate the need for short circuit protection; and low overall component count.

摘要翻译： 作为其第一级的AC / DC功率转换器具有电容器分压器和整流器，并且作为第二级，具有开关模式电源。 这种配置可能适用于低功率低压航空航天应用。 电路的优点可能包括小的无功元件尺寸; 接近正弦输入电流，由低浪涌电流导致的低EMI辐射; 本征电流限制可以消除短路保护的需要; 并且总体组件数量较少。

公开(公告)号：US07508642B2

公开(公告)日：2009-03-24

申请号：US11480450

申请日：2006-07-05

申请人： Yang Ye

发明人： Yang Ye

IPC分类号： H02H5/04 ,  G06G7/56

CPC分类号： H02H6/005 ,  H02H3/0935 ,  H02H6/00 ,  H02H7/228

摘要： A virtual ΔT trip criterion is implemented in an electrical power distribution system to provide current-based tripping for a solid state power switching device. A first-order system model is implemented either by hardware or software to represent a rise in temperature of the electrical wire through which power is supplied. When the simulated temperature exceeds a threshold, the solid state power switching device may be tripped.

摘要翻译： 在配电系统中实现虚拟的DeltaT跳闸标准，以为固态功率开关装置提供基于电流的跳闸。 通过硬件或软件来实现一阶系统模型，以表示通过其供电的电线的温度升高。 当模拟温度超过阈值时，固态电源开关装置可能跳闸。

公开(公告)号：US20070268726A1

公开(公告)日：2007-11-22

申请号：US11434245

申请日：2006-05-16

申请人： Hassan Ali Kojori ,  Yang Ye

发明人： Hassan Ali Kojori ,  Yang Ye

IPC分类号： H02J1/10

CPC分类号： H02J1/10 ,  H03K17/161 ,  H03K17/302 ,  H03K17/6872 ,  H03K17/6877 ,  Y02T50/54

摘要： A method and an apparatus are used for power supply input connection. The apparatus according to one embodiment comprises a first switch module (143_1) connected to a first power supply input (Vin1); a first controller module (145_1) connected to the first power supply input (Vin1) and to a secondary power connection (Vc), wherein the first controller module (145_1) puts the first switch module (143_1) in a first operating state when a parameter relating to the first power supply input (Vin1) is larger than a parameter relating to the secondary power connection (Vc), and puts the first switch module (143_1) in a second operating state when the parameter relating to the first power supply input (Vin1) is smaller than the parameter relating to the secondary power connection (Vc); and a first driver module (160_1) connected to the first controller module (145_1) and to the first switch module (143_1), wherein the first driver module (160_1) modifies a parameter relating to a drive characteristic of the first switch module (143_1).

摘要翻译： 用于电源输入连接的方法和装置。 根据一个实施例的装置包括连接到第一电源输入端（Vin 1）的第一开关模块（143_1）; 连接到第一电源输入（Vin 1）和辅助电力连接（Vc）的第一控制器模块（145_1），其中第一控制器模块（145_1）将第一开关模块（143_1） 在与第一电源输入（Vin 1）相关的参数大于与次级电源连接（Vc）相关的参数的第一运行状态下，将第一开关模块（143_1）置于第二运行状态 当与第一电源输入（Vin 1）相关的参数小于与次级电源连接（Vc）有关的参数时; 以及连接到第一控制器模块（145_1）和第一开关模块（143_1）的第一驱动器模块（160_1），其中第一驱动器模块（160_1）修改与驱动器 第一开关模块（143_1）的特性。

公开(公告)号：US11414427B2

公开(公告)日：2022-08-16

申请号：US16646694

申请日：2018-09-07

申请人： Yang Ye ,  Sheng Yao ,  Hui-Yin Li ,  Qun Li

发明人： Yang Ye ,  Sheng Yao ,  Hui-Yin Li ,  Qun Li

IPC分类号： C07D491/20 ,  C07C59/255 ,  C07C309/04 ,  C07C309/05 ,  C07C309/19

摘要： Disclosed are stemospironine salts of Formula 1: wherein HX represents HCl, HBr, L-tartaric acid, D-tartaric acid, sulfuric acid, (+)-(1S)-10-camphorsulfonic acid, ethanesulfonic acid and ethane-1,2-disulfonic acid. This invention also provides crystalline polymorph forms of the compound of Formula 1 wherein HX is HCl, stemospironine hydrochloride. This invention also provides a new crystalline form of the compound of Formula 2, stemospironine free base: Also disclosed are compositions containing one or more compounds of Formula 1, methods for controlling cough comprising administering a therapeutically effective amount of a compound of Formula 1, and methods for preparing compounds of Formula 1. Also disclosed is a method for preparing crystalline stemospironine hydrochloride polymorph Form II from stemospironine hydrochloride polymorph Form I.

公开(公告)号：US20090228223A1

公开(公告)日：2009-09-10

申请号：US12041941

申请日：2008-03-04

申请人： ZHENNING LIU ,  Randy J. Fuller ,  Wenjiang Yu ,  Yang Ye ,  Guangjun G. Liu

发明人： ZHENNING LIU ,  Randy J. Fuller ,  Wenjiang Yu ,  Yang Ye ,  Guangjun G. Liu

IPC分类号： H02H3/00 ,  G01R31/02

CPC分类号： G01R31/008 ,  G01R31/025 ,  G01R31/086 ,  G01R31/11 ,  H04B3/546 ,  H04B2203/5445 ,  H04B2203/5458 ,  H04B2203/5495

摘要： A power line communication-based aircraft power distribution system may allow for both power line communication (PLC) technology and spread spectrum time domain reflectometry (SSTDR) technology to be utilized in aircraft power distribution systems to achieve key maintenance functions. Unlike conventional power distribution systems, which may, for example, use only SSTDR for fault detection, the present invention includes a hardware platform that may allow both the PLC and the SSTDR to be utilized in aircraft power distribution systems to achieve key maintenance functions, such as real time wire fault location, and cost and weight savings. Further, unlike conventional power distribution systems, which may only detect and locate damage in feeder conductor wire sections before the power is applied to the load, the power distribution system of the present invention may permit real time wire fault location.

摘要翻译： 基于电力线通信的飞机配电系统可以允许在飞机配电系统中利用电力线通信（PLC）技术和扩频时域反射计（SSTDR）技术来实现关键维护功能。 与常规配电系统不同，传统配电系统可能例如仅使用SSTDR进行故障检测，本发明包括硬件平台，其可以允许PLC和SSTDR在飞机配电系统中使用以实现关键维护功能，例如 作为实时线路故障定位，并节省成本和重量。 此外，与在功率施加到负载之前只能检测和定位馈线导线部分中的损坏的常规配电系统不同，本发明的配电系统可以允许实时线路故障定位。

公开(公告)号：US20090122454A1

公开(公告)日：2009-05-14

申请号：US11938693

申请日：2007-11-12

申请人： Ted J. Gayowsky ,  Yang Ye ,  Zhenning Z. Liu ,  Randy J. Fuller

发明人： Ted J. Gayowsky ,  Yang Ye ,  Zhenning Z. Liu ,  Randy J. Fuller

IPC分类号： H02H5/04

CPC分类号： H02H6/005 ,  H02H3/093 ,  H02H7/222

摘要： An electrical overload protection system may be based on a solid state control system. A solid state switch may open responsively to commands for a solid-state controller. The controller may perform calculations to determine accumulated energy in a protected conductor. The calculations may be based, in part, on samplings of current in the protected conductor and ambient temperature to which the conductor may be exposed.

摘要翻译： 电气过载保护系统可以基于固态控制系统。 固态开关可以响应于固态控制器的命令而打开。 控制器可以执行计算以确定受保护导体中的累积能量。 计算可以部分地基于受保护导体中的电流采样和导体可能暴露于的环境温度。