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61 条记录 (耗时 0.036 秒)

    Bicyclic macrolide derivatives
    1.
    发明授权
    Bicyclic macrolide derivatives 失效
    双环大环内酯衍生物

    公开(公告)号：US06790835B1

    公开(公告)日：2004-09-14

    申请号：US10455219

    申请日：2003-06-05

    申请人： Yao-Ling Qiu ,  Ly Tam Phan ,  Tongzhu Liu ,  Zhigang Chen ,  Yat Sun Or

    发明人： Yao-Ling Qiu ,  Ly Tam Phan ,  Tongzhu Liu ,  Zhigang Chen ,  Yat Sun Or

    IPC分类号： A61K3170

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    Bicyclic ketolide derivatives
    2.
    发明授权
    Bicyclic ketolide derivatives 失效
    双环酮内酯衍生物

    公开(公告)号：US06765016B1

    公开(公告)日：2004-07-20

    申请号：US10455648

    申请日：2003-06-05

    申请人： Yao-Ling Qiu ,  Ly Tam Phan ,  Zhigang Chen ,  Tongzhu Liu ,  Yat Sun Or

    发明人： Yao-Ling Qiu ,  Ly Tam Phan ,  Zhigang Chen ,  Tongzhu Liu ,  Yat Sun Or

    IPC分类号： A61K3135

    CPC分类号： A61K31/35 ,  C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6,11-bridged biaryl macrolides
    8.
    发明授权
    6,11-bridged biaryl macrolides 有权
    6,11桥接的联芳基大环内酯类

    公开(公告)号：US08354383B2

    公开(公告)日：2013-01-15

    申请号：US12399801

    申请日：2009-03-06

    申请人： In Jong Kim ,  Tongzhu Liu ,  Jiang Long ,  Guoqiang Wang ,  Yao-Ling Qiu ,  Heejin Kim ,  Yanchun Wang ,  Ly Tam Phan ,  Yat Sun Or

    发明人： In Jong Kim ,  Tongzhu Liu ,  Jiang Long ,  Guoqiang Wang ,  Yao-Ling Qiu ,  Heejin Kim ,  Yanchun Wang ,  Ly Tam Phan ,  Yat Sun Or

    IPC分类号： A61K31/70 ,  C07H17/08

    CPC分类号： C07D493/08 ,  C07F9/65586 ,  C07H17/08

    摘要： The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I，II或X的化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6,11-bicyclolides: bridged biaryl macrolide derivatives
    9.
    发明授权
    6,11-bicyclolides: bridged biaryl macrolide derivatives 有权
    6,11-双环氯化物：桥连联芳基大环内酯衍生物

    公开(公告)号：US08273720B2

    公开(公告)日：2012-09-25

    申请号：US12388333

    申请日：2009-02-18

    申请人： In Jong Kim ,  Tongzhu Liu ,  Heejin Kim ,  Yanchun Wang ,  Yao-Ling Qiu ,  Ly Tam Phan ,  Yat Sun Or

    发明人： In Jong Kim ,  Tongzhu Liu ,  Heejin Kim ,  Yanchun Wang ,  Yao-Ling Qiu ,  Ly Tam Phan ,  Yat Sun Or

    IPC分类号： A61K31/70 ,  C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。