公开(公告)号：US5964712A

公开(公告)日：1999-10-12

申请号：US849351

申请日：1997-06-06

申请人： Yasuhiro Kubo ,  Katsuhiro Morisawa ,  Yasushi Zasu ,  Eiji Ikegami ,  Kazunori Tsutsui ,  Tamotsu Hamao ,  Masaaki Mori ,  Takashi Maruyama

发明人： Yasuhiro Kubo ,  Katsuhiro Morisawa ,  Yasushi Zasu ,  Eiji Ikegami ,  Kazunori Tsutsui ,  Tamotsu Hamao ,  Masaaki Mori ,  Takashi Maruyama

IPC分类号： A61B5/00 ,  A61B5/08 ,  A61B5/083 ,  A61B5/097 ,  A61B10/00 ,  G01N1/22 ,  G01N21/03 ,  G01N21/11 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N21/35 ,  G01N21/59 ,  G01N33/00 ,  G01N33/497 ,  G01N35/08 ,  B01L3/00

CPC分类号： G01N21/3504 ,  A61B10/00 ,  A61B5/097 ,  G01N21/0332 ,  G01N21/11 ,  G01N21/274 ,  G01N21/314 ,  A61B2010/0087 ,  A61B5/0059 ,  A61B5/0836 ,  G01N33/0006 ,  G01N33/497

摘要： A correction curve (FIG. 19) is prepared by plotting .sup.12 CO.sub.2 concentrations and .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratios which are determined on the basis of a calibration curve and .sup.13 CO.sub.2 and .sup.12 CO.sub.2 absorbances of gaseous samples having the same .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio but known different .sup.12 CO.sub.2 concentrations. A gaseous test sample containing .sup.13 CO.sub.2 and .sup.12 CO.sub.2 as component gases is introduced into a cell, and spectrometrically measured. A .sup.12 CO.sub.2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the .sup.12 CO.sub.2 concentration of the gaseous test sample thus determined. A measured .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved. A breath sampling bag and gas measuring system is also disclosed where each is configured such that breath inlets of the gas measuring apparatus are prevented from being respectively connected to the wrong breath introduction pipes of the breath sampling bag.

摘要翻译： PCT No.PCT / JP96 / 02876 Sec。 371日期：1997年6月6日 102（e）日期1996年6月6日PCT提交1996年10月2日PCT公布。 公开号WO97 / 14029 日期1997年04月17日通过绘制12CO2浓度和13CO2 / 12CO2浓度比，制备校正曲线（图19），其基于校准曲线确定，并且具有13CO 2 / 12CO 2浓度的气态样品的13CO 2和12 CO 2吸光度 比例但已知不同的12CO2浓度。 将含有作为组分气体的13CO 2和12 CO 2的气态测试样品引入到电池中，并进行光谱测量。 通过光谱测量法测定气态测试样品的12CO2浓度。 基于如此确定的气体试样的校正曲线和12CO 2浓度获得浓度比校正值。 测量的13CO 2 / 12CO 2浓度比除以由此获得的用于校正13CO 2 / 12CO 2浓度比的浓度比校正值。 因此，能够提高成分气体的浓度比的测定精度。 还公开了一种呼吸取样袋和气体测量系统，其中每个呼气采样袋和气体测量系统被配置为使得气体测量装置的呼吸入口被防止分别连接到呼吸取样袋的错误的呼吸导管。

公开(公告)号：US06274870B1

公开(公告)日：2001-08-14

申请号：US09303427

申请日：1999-05-03

申请人： Yasuhiro Kubo ,  Katsuhiro Morisawa ,  Yasushi Zasu ,  Eiji Ikegami ,  Kazunori Tsutsui ,  Tamotsu Hamao ,  Masaaki Mori ,  Takashi Maruyama

发明人： Yasuhiro Kubo ,  Katsuhiro Morisawa ,  Yasushi Zasu ,  Eiji Ikegami ,  Kazunori Tsutsui ,  Tamotsu Hamao ,  Masaaki Mori ,  Takashi Maruyama

IPC分类号： G01N2135

CPC分类号： G01N21/3504 ,  A61B5/0059 ,  A61B5/0836 ,  A61B5/097 ,  A61B10/00 ,  A61B2010/0087 ,  G01N21/0332 ,  G01N21/11 ,  G01N21/274 ,  G01N21/314 ,  G01N33/0006 ,  G01N33/497

摘要： A correction curve (FIG. 19) is prepared by plotting 12CO2 concentrations and 13CO2/12CO2 concentration ratios which are determined on the basis of a calibration curve and 13CO2 and 12CO2 absorbances of gaseous samples having the same 13CO2/12CO2 concentration ratio but known different 12CO2 concentrations. A gaseous test sample containing 13CO2 and 12CO2 as component gases is introduced into a cell, and spectrometrically measured. A 12CO2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the 12CO2 concentration of the gaseous test sample thus determined. A measured 13CO2/12CO2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the 13CO2/12CO2 concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved.

摘要翻译： 通过绘制12CO2浓度和13CO2 / 12CO2浓度比，通过绘制12CO2浓度和13CO2 / 12CO2浓度比来制备校正曲线（13CO2 / 12CO2浓度比），这些浓度比是根据13CO2 / 12CO2浓度比相同但已知不同12CO2的气态样品的校正曲线和13CO2和12CO2吸光度确定的 浓度 将含有作为组分气体的13CO 2和12 CO 2的气态测试样品引入到电池中，并进行光谱测量。 通过光谱测量法测定气态测试样品的12CO2浓度。 基于如此确定的气体试样的校正曲线和12CO 2浓度获得浓度比校正值。 测量的13CO 2 / 12CO 2浓度比除以由此获得的用于校正13CO 2 / 12CO 2浓度比的浓度比校正值。 因此，能够提高成分气体的浓度比的测定精度。

公开(公告)号：US07749436B2

公开(公告)日：2010-07-06

申请号：US10577451

申请日：2004-10-29

申请人： Masaaki Mori ,  Yasuhiro Kubo ,  Yasushi Zasu ,  Masayuki Tani ,  Tamotsu Hamao

发明人： Masaaki Mori ,  Yasuhiro Kubo ,  Yasushi Zasu ,  Masayuki Tani ,  Tamotsu Hamao

IPC分类号： G01N33/00

CPC分类号： G01N21/3504 ,  A61B5/0836

摘要： As previous processing of measurement in which gas to be measured containing, as gas components, carbon dioxide 13CO2 and carbon dioxide 12CO2, is introduced into a cell, and in which the intensities of transmitted lights having wavelengths suitable for measurement of the respective gas components, are measured and then data-processed to measure the concentrations of the gas components, the air having a predetermined volume Va is sucked by a gas injection device 21, a gas exhaust valve V6 of a cell 11 is closed and the air stored in the gas injection device 21 is transferred to the cell 11 filled with the air at an atmospheric pressure, thereby to pressurize the cell inside. The pressure thus pressurized is measured as P. The cell volume Vc is subtracted from the product obtained by multiplying the sum. V0 of the volume Va and Vc the cell volume Vc, by the ratio P0/P in which P0 is the target pressure of the gas to be measured at which a calibration curve has been prepared for an isotope gas analysis and measurement, thus determining the one-time gas injection amount of the gas injection device 21. Thus, measured concentration variations based on changes in atmospheric pressure can be corrected.

摘要翻译： 作为先前的测量处理，其中将待测量的气体作为气体组分含有二氧化碳13CO 2和二氧化碳12CO 2，并将其中的辐射强度引入到电池中，并且其中具有适于测量各个气体组分的波长的透射光的强度， 被测量，然后进行数据处理以测量气体组分的浓度，具有预定体积Va的空气由气体注入装置21吸入，单元11的排气阀V6关闭，并且存储在气体中的空气 注入装置21在大气压下转移到填充有空气的电池单元11，从而对电池内部进行加压。 将如此加压的压力测量为P.从通过乘以和获得的乘积中减去单元容积Vc。 V0为体积Va，Vc为电池体积Vc，P0 / P为P0为待测气体的目标压力，其中准备了用于同位素气体分析和测量的校准曲线，从而确定 气体注入装置21的一次气体注入量。因此，可以校正基于大气压变化的测量浓度变化。

公开(公告)号：US06940083B2

公开(公告)日：2005-09-06

申请号：US10381314

申请日：2001-09-19

申请人： Masaaki Mori ,  Yasuhiro Kubo ,  Masahiko Miyoshi ,  Tamotsu Hamao ,  Hiroaki Mizui

发明人： Masaaki Mori ,  Yasuhiro Kubo ,  Masahiko Miyoshi ,  Tamotsu Hamao ,  Hiroaki Mizui

IPC分类号： A61B5/083 ,  G01N21/35 ,  G01N33/00 ,  G01N15/06

CPC分类号： A61B5/0836 ,  G01N21/3504 ,  G01N33/004 ,  G01N2021/3536 ,  Y02A50/2342

摘要： In an isotopic gas analyzer, a gas injector (21) is provided for pressurizing a gas specimen in cells (11a,11b). The pressurization of the gas specimen virtually produces the same effect as increasing the concentration of carbon dioxide in the gas specimen, thereby improving an S/N ratio for the analysis and hence data reproducibility.

摘要翻译： 在同位素气体分析仪中，设置有气体注入器（21），用于对单元（11a，11b）中的气体样本进行加压。 气体样本的加压实际上产生与增加气体样本中二氧化碳浓度相同的效果，从而提高了分析的S / N比，从而提高了数据再现性。

公开(公告)号：US20070077167A1

公开(公告)日：2007-04-05

申请号：US10577451

申请日：2004-10-29

申请人： Masaaki Mori ,  Yasuhiro Kubo ,  Yasuhiro Zasu ,  Masayuki Tani ,  Tamotsu Hamao

发明人： Masaaki Mori ,  Yasuhiro Kubo ,  Yasuhiro Zasu ,  Masayuki Tani ,  Tamotsu Hamao

IPC分类号： G01N27/00

CPC分类号： G01N21/3504 ,  A61B5/0836

摘要： As previous processing of measurement in which gas to be measured containing, as gas components, carbon dioxide 13CO2 and carbon dioxide 12CO2, is introduced into a cell, and in which the intensities of transmitted lights having wavelengths suitable for measurement of the respective gas components, are measured and then data-processed to measure the concentrations of the gas components, the air having a predetermined volume Va is sucked by a gas injection device 21, a gas exhaust valve V6 of a cell 11 is closed and the air stored in the gas injection device 21 is transferred to the cell 11 filled with the air at an atmospheric pressure, thereby to pressurize the cell inside. The pressure thus pressurized is measured as P. The cell volume Vc is subtracted from the product obtained by multiplying the sum. V0 of the volume Va and Vc the cell volume Vc, by the ratio P0/P in which P0 is the target pressure of the gas to be measured at which a calibration curve has been prepared for an isotope gas analysis and measurement, thus determining the one-time gas injection amount of the gas injection device 21. Thus, measured concentration variations based on changes in atmospheric pressure can be corrected.

摘要翻译： 作为先前的测量处理，其中待测量的气体含有作为气体组分的二氧化碳气体和二氧化碳气体二氧化碳 > 2 <！ - SIPO - >导入到电池中，并且其中测量了具有适于测量各个气体成分的波长的透射光的强度，然后进行数据处理以测量气体成分的浓度，空气 具有预定体积Va的气体由气体注入装置21吸入，电池单元11的排气阀V 6关闭，并且存储在气体注入装置21中的空气被传送到充满大气压的空气的电池单元11 从而对电池内部进行加压。 将如此加压的压力测量为P.从通过乘以和获得的乘积中减去单元容积Vc。 V0为体积Va，Vc为电池体积Vc，P0 / P为P0为待测气体的目标压力，其中准备了用于同位素气体分析和测量的校准曲线，从而确定 气体注入装置21的一次气体注入量。 因此，可以校正基于大气压变化的测量浓度变化。

公开(公告)号：US06444985B1

公开(公告)日：2002-09-03

申请号：US09341045

申请日：1999-07-01

申请人： Masaaki Mori ,  Yasuhiro Kubo ,  Kazunori Tsutsui

发明人： Masaaki Mori ,  Yasuhiro Kubo ,  Kazunori Tsutsui

IPC分类号： G01N2135

CPC分类号： G01N21/3504 ,  G01N33/0006

摘要： A test gas sample containing carbon dioxide 13CO2 as a component gas is introduced into a cell, then the absorbance of light transmitted therethrough at a wavelength suitable for the component gas 13CO2 is determined, and the concentration of the component gas is determined on the basis of a calibration curve prepared through measurement on test gas samples each containing the component gas in a known concentration. Further, the concentration of water vapor contained in the test gas sample is measured, and the concentration of the component gas in the test gas sample is corrected in accordance with the measured water vapor concentration on the basis of a correction curve prepared through measurement on the test gas samples each containing water vapor in a known concentration (FIG. 4). With the spectrometry, the concentration ratio of the component gas can precisely be determined and corrected by measuring the moisture content in the test gas sample.

摘要翻译： 将含有作为成分气体的二氧化碳13CO 2的试验气体样品引入电池中，然后确定以适合于成分气体13CO2的波长透射的光的吸光度，并且基于 通过测量每个含有已知浓度的组分气体的测试气体样品制备的校准曲线。 此外，测定试验气体试样中含有的水蒸气浓度，根据测定的水蒸气浓度，根据对测定气体样品的测定准备的校正曲线，对试验气体试样中的成分气体的浓度进行校正 测试每个含有已知浓度的水蒸气的气体样品（图4）。 通过光谱测定，可以通过测量测试气体样品中的含水量来精确地确定和校正组分气体的浓度比。

公开(公告)号：US06455852B2

公开(公告)日：2002-09-24

申请号：US09929033

申请日：2001-08-15

申请人： Masaaki Mori ,  Yasuhiro Kubo ,  Kazunori Tsutsui

发明人： Masaaki Mori ,  Yasuhiro Kubo ,  Kazunori Tsutsui

IPC分类号： G01N2135

CPC分类号： G01N21/3504 ,  G01N33/0006

摘要： A test gas sample containing carbon dioxide 13CO2 as a component gas is introduced into a cell, then the absorbance of light transmitted therethrough at a wavelength suitable for the component gas 13CO2 is determined, and the concentration of the component gas is determined on the basis of a calibration curve prepared through measurement on test gas samples each containing the component gas in a known concentration. Further, the concentration of water vapor contained in the test gas sample is measured, and the concentration of the component gas in the test gas sample is corrected in accordance with the measured water vapor concentration on the basis of a correction curve prepared through measurement on the test gas samples each containing water vapor in a known concentration (FIG. 4). With the spectrometry, the concentration ratio of the component gas can precisely be determined and corrected by measuring the moisture content in the test gas sample.

公开(公告)号：US20050191210A1

公开(公告)日：2005-09-01

申请号：US11119704

申请日：2005-05-03

申请人： Masaaki Mori ,  Masao Ninomiya ,  Tomokuni Inoue ,  Eiji Ikegami ,  Akira Tanaka

发明人： Masaaki Mori ,  Masao Ninomiya ,  Tomokuni Inoue ,  Eiji Ikegami ,  Akira Tanaka

IPC分类号： G01N31/22 ,  G01N21/78 ,  G01N21/86 ,  G01N33/52

CPC分类号： G01N21/8483 ,  Y10T436/112499 ,  Y10T436/115831

摘要： In a test strip measuring method in which a coloration measurement is conducted while a test strip (4) is being moved, there are detected the optical characteristics R of the ground of a test strip and the optical characteristics T of a test line (4b) which has appeared on the test strip, and the test strip is judged based on the difference or ratio between R and T. Even though the ground of the test strip presents variations in optical characteristics, and even though there are variations among samples or among test strips, such variations can be absorbed, thus assuring an accurate judgment.

摘要翻译： 在测试条（4）移动时进行着色测量的测试条测量方法中，检测测试条的接地的光学特性R和测试线的光学特性T（4 b ），并且基于R和T之间的差异或比例来判断测试条。即使测试条的地面呈现光学特性的变化，并且即使在样品之间或之间存在差异 测试条可以吸收这种变化，从而确保准确的判断。

公开(公告)号：US07833792B2

公开(公告)日：2010-11-16

申请号：US11119704

申请日：2005-05-03

申请人： Masaaki Mori ,  Masao Ninomiya ,  Tomokuni Inoue ,  Eiji Ikegami ,  Akira Tanaka

发明人： Masaaki Mori ,  Masao Ninomiya ,  Tomokuni Inoue ,  Eiji Ikegami ,  Akira Tanaka

IPC分类号： G01N33/48

CPC分类号： G01N21/8483 ,  Y10T436/112499 ,  Y10T436/115831

摘要： In a test strip measuring method in which a coloration measurement is conducted while a test strip (4) is being moved, there are detected the optical characteristics R of the ground of a test strip and the optical characteristics T of a test line (4b) which has appeared on the test strip, and the test strip is judged based on the difference or ratio between R and T. Even though the ground of the test strip presents variations in optical characteristics, and even though there are variations among samples or among test strips, such variations can be absorbed, thus assuring an accurate judgment.

摘要翻译： 在测试条（4）移动时进行着色测量的测试条测量方法中，检测测试条的接地的光学特性R和测试线（4b）的光学特性T， 其出现在测试条上，并且基于R和T之间的差异或比例来判断测试条。即使测试条的地面呈现光学特性的变化，并且即使样品之间或测试中存在变化 可以吸收这种变化，从而确保准确的判断。

公开(公告)号：US09591992B2

公开(公告)日：2017-03-14

申请号：US13565437

申请日：2012-08-02

申请人： Yasuhiro Kubo ,  Masaaki Mori

发明人： Yasuhiro Kubo ,  Masaaki Mori

IPC分类号： A61B5/08 ,  A61B5/083 ,  G01N1/22 ,  G01N21/3504 ,  G01N33/497 ,  A61B5/097

CPC分类号： A61B5/0836 ,  A61B5/097 ,  G01N1/22 ,  G01N21/3504 ,  G01N33/497

摘要： An exhalation collected in a breath bag capable of expanding and contracting is sucked into a gas inlet vessel 21 with a given volume (Va), and then the gas inlet vessel 21 is communicated by means of valve V2 with a cell 11 that is maintained at an atmospheric pressure by being pre-filled with a sample gas or reference gas. After the communication, the gas pressure is measured by a pressure sensor 16 attached to the cell 11. Whether the exhalation collected in the breath bag is below a given amount or not can be accurately judged.

摘要翻译： 将收集在能够膨胀和收缩的呼吸袋中的呼气吸入具有给定体积（Va）的气体入口容器21中，然后气体入口容器21通过阀V2与保持在 通过预先填充有样品气体或参考气体的大气压力。 在通信之后，气体压力通过安装在电池单元11上的压力传感器16来测量。可以准确地判断呼吸袋中收集的呼气是否低于给定量。