公开(公告)号：US4973576A

公开(公告)日：1990-11-27

申请号：US165741

申请日：1988-03-09

申请人： Shuichi Sakamoto ,  Makoto Takeuchi ,  Yasuo Isomura ,  Kunihiro Niigata ,  Tetsushi Abe ,  Kousei Kawamuki ,  Masafumi Kudou

发明人： Shuichi Sakamoto ,  Makoto Takeuchi ,  Yasuo Isomura ,  Kunihiro Niigata ,  Tetsushi Abe ,  Kousei Kawamuki ,  Masafumi Kudou

IPC分类号： C07F9/653

CPC分类号： C07F9/653

摘要： "Novel bisphosphonic acid derivatives, and a bone resorption-inhibitor and an anti-arthritis containing a bisphosphonic acid derivative represented by the formula (I): ##STR1## wherein R.sup.2 represents a hydrogen atom, an alkyl group, etc.,R.sup.2 represents a hydrogen atom or a lower alkanoyl group,R.sup.3, R.sup.4, R.sup.5 and R.sup.6 may be the same or different, each represents a hydrogen atom or lower alkyl group."

公开(公告)号：US4970335A

公开(公告)日：1990-11-13

申请号：US300350

申请日：1989-01-23

申请人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

发明人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

IPC分类号： C07F9/38 ,  C07F9/40

CPC分类号： C07F9/3873 ,  C07F9/405 ,  Y10S514/825

摘要： (Cycloalkylamino)methylenebis(phosphonic acid) represented by the general formula: ##STR1## in which, R, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent a hydrogen atom or a lower alkyl group, and n represents an integer from 3 to 10, a lower alkyl ester thereof or a pharmaceutically acceptable salt thereof; and a bone-resorption inhibitor and an anti-arthritis containing the same.

公开(公告)号：US5041428A

公开(公告)日：1991-08-20

申请号：US551434

申请日：1990-07-10

申请人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

发明人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

IPC分类号： C07F9/38 ,  C07F9/40

CPC分类号： C07F9/3873 ,  C07F9/405 ,  Y10S514/825

摘要： (Cycloalkylamino)methylenebis(phosphonic acid) represented by the general formula: ##STR1## in which, R, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent a hydrogen atom or a lower alkyl group, and n represents an integer from 3 to 10, a lower alkyl ester thereof or a pharmaceutically acceptable salt thereof; and a bone-resorption inhibitor and an anti-arthritis containing the same.

公开(公告)号：US5013725A

公开(公告)日：1991-05-07

申请号：US495388

申请日：1990-03-16

申请人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

发明人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

IPC分类号： C07F9/38 ,  C07F9/40 ,  C07F9/655 ,  C07F9/6553

CPC分类号： C07F9/655363 ,  C07F9/3873 ,  C07F9/405 ,  C07F9/655

摘要： Substituted aminomethylenebis(phosphonic acid) derivatives represented by the general formula: ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 may be the same or different, each represents a hydrogen atom or a lower alkyl group; "m" is zero or represents an integer from 1 to 4; and a ring "A" represents a cycloalkenyl group having 5 to 8 carbon atoms, a bicycloheptyl group, a bicycloheptenyl group or a saturated heterocyclic group having 4 to 7 carbon atoms and containing an oxygen atom, a sulfur atom, a sulfinyl group (--SO--) or a sulfonyl group (--SO.sub.2 --), or pharmaceutically acceptable salts thereof.

公开(公告)号：US4933472A

公开(公告)日：1990-06-12

申请号：US333971

申请日：1989-04-05

申请人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

发明人： Yasuo Isomura ,  Makoto Takeuchi ,  Shuichi Sakamoto ,  Tetsushi Abe

IPC分类号： C07F9/38 ,  C07F9/40 ,  C07F9/655 ,  C07F9/6553

CPC分类号： C07F9/655363 ,  C07F9/3873 ,  C07F9/405 ,  C07F9/655

摘要： Substituted aminomethylenebis(phosphonic acid) derivatives represented by the general formula: ##STR1## in which R.sup.1, R.sup.2 R.sup.3 and R.sup.4 may be the same or different, each represents a hydrogen atom or a lower alkyl group; "m" is zero or represents an integer from 1 to 4; and a ring "A" represents a cycloalkenyl group having 5 to 8 carbon atoms, a bicycloheptyl group, a bicycloheptenyl group or a saturated heterocyclic group having 4 to 7 carbon atoms and containing an oxygen atom, a sulfur atom, a sulfinyl group (--SO--) or a sulfonyl group (--SO.sub.2 --),or pharmaceutically acceptable salts thereof.

摘要翻译： 由以下通式表示的取代的氨基亚甲基双（膦酸）衍生物：其中R 1，R 2 + L，R 3和R 4可以相同或不同，各自表示氢原子或低级烷基; “m”为0或表示1至4的整数; 环“A”表示碳原子数5〜8的环烯基，双环庚基，双环庚烯基或碳原子数4〜7的饱和杂环基，含有氧原子，硫原子，亚磺酰基（ - SO-）或磺酰基（-SO 2 - ）或其药学上可接受的盐。

公开(公告)号：US4636516A

公开(公告)日：1987-01-13

申请号：US347982

申请日：1982-02-11

申请人： Kazuo Kubo ,  Yasuo Isomura ,  Shuichi Sakamoto ,  Hiroshige Homma

发明人： Kazuo Kubo ,  Yasuo Isomura ,  Shuichi Sakamoto ,  Hiroshige Homma

IPC分类号： C07D233/54 ,  C07D233/64 ,  C07D233/66 ,  C07D233/70 ,  C07D233/84 ,  C07D263/32 ,  C07D277/22 ,  C07D277/24 ,  C07D277/36 ,  C07D277/42 ,  C07D513/04 ,  C07D513/06 ,  C07D233/42 ,  A61K31/415 ,  A61K31/425

CPC分类号： C07D233/64 ,  C07D233/70 ,  C07D233/84 ,  C07D263/32 ,  C07D277/24 ,  C07D277/36 ,  C07D277/42 ,  C07D513/04 ,  C07D513/06

摘要： Novel 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds shown by the formula ##STR1## wherein .circle.Het -- represents a specific heterocyclic group and the salts thereof.The compounds have an anti-inflammatory, an anti-pyretic, an analgesic, an anti-arthritic, and an immunoregulatory activity. Hence, they are particularly useful as an antirheumatics.

摘要翻译： 新颖的3,5-二叔丁基-4-羟基苯基取代的杂环化合物，其由式表示，其中＆cir＆Het-表示特定的杂环基团及其盐。 该化合物具有抗炎，抗热解，止痛，抗关节炎和免疫调节活性。 因此，它们作为抗风湿剂特别有用。

公开(公告)号：US20090215941A1

公开(公告)日：2009-08-27

申请号：US12433603

申请日：2009-04-30

申请人： Takeo Nakazono ,  Shuichi Sakamoto

发明人： Takeo Nakazono ,  Shuichi Sakamoto

IPC分类号： C08K5/09

CPC分类号： C08K3/24 ,  B60C1/0016 ,  C08K5/005 ,  C08K5/098 ,  C08L21/00

摘要： The present invention provides a rubber composition for a tire tread which can prepare a tire having improved grip properties under conditions of a high temperature, and a pneumatic tire comprising the same.The present invention relates to the rubber composition for a tire tread containing more than 5 parts by weight of a basic antioxidant based on 100 parts by weight of the diene rubber components, wherein a metallic compound is a metallic compound comprising (1) a metallic salt of an organic carboxylic acid or (2) an inorganic metallic salt and an acid, and the pneumatic tire having a tire tread comprising the same.

摘要翻译： 本发明提供一种用于轮胎胎面的橡胶组合物，其可以制备在高温条件下具有改进的抓地性能的轮胎，以及包括该轮胎的充气轮胎。 本发明涉及一种轮胎胎面用橡胶组合物，其含有基于100重量份二烯橡胶组分的5重量份以上的碱性抗氧化剂，其中金属化合物是金属化合物，其包含（1）金属盐 的有机羧酸或（2）无机金属盐和酸，并且所述充气轮胎具有包含该轮胎胎面的轮胎胎面。

公开(公告)号：US07069332B2

公开(公告)日：2006-06-27

申请号：US09739691

申请日：2000-12-20

申请人： Koichi Shibata ,  Masaru Igawa ,  Koichi Morita ,  Shuichi Sakamoto

发明人： Koichi Shibata ,  Masaru Igawa ,  Koichi Morita ,  Shuichi Sakamoto

IPC分类号： G06F15/16

CPC分类号： H04N21/21 ,  H04N21/23

摘要： A video server for distributing a digitized video content includes a unit for determining whether or not a video content requested from a terminal is stored in the video server, a unit for issuing a transmission request to another server for transmitting the video thereto in accordance with the HTTP protocol when the video content requested from the terminal is not stored in the video server, and a unit for receiving the video content transmitted from the other video server in accordance with the HTTP protocol, and transmitting the video content to the terminal in accordance with IP multicast or HTTP protocol.

公开(公告)号：US6096743A

公开(公告)日：2000-08-01

申请号：US809087

申请日：1997-03-05

申请人： Jun-ichi Shishikura ,  Hiroshi Inami ,  Shuichi Sakamoto ,  Shin-ichi Tsukamoto ,  Masao Sasamata ,  Masamichi Okada ,  Mitsuo Fujii

发明人： Jun-ichi Shishikura ,  Hiroshi Inami ,  Shuichi Sakamoto ,  Shin-ichi Tsukamoto ,  Masao Sasamata ,  Masamichi Okada ,  Mitsuo Fujii

IPC分类号： C07D403/04 ,  A61K31/498 ,  A61K31/4985 ,  A61P25/14 ,  A61P25/28 ,  C07D241/44 ,  C07D471/04 ,  C07D521/00 ,  C07D403/10

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D241/44 ,  C07D249/08

摘要： A 1,2,3,4-tetrahydroquinoxalinedione derivative represented by the following formula (I) or salt thereof, an NMDA-glycine receptor and/or AMPA receptor antagonist or kainic acid neurotoxicity inhibitor containing the derivative or salt. In addition, a pharmaceutical composition comprising said compound and a pharmaceutically acceptable carrier: ##STR1## wherein the substituents are as described in the specification.

摘要翻译： PCT No.PCT / JP95 / 01922 Sec。 371日期1997年3月5日 102（e）1997年3月5日PCT PCT 1995年9月25日PCT公布。 公开号WO96 / 10023 日本1996年4月4日由下式（I）表示的1,2,3,4-四氢喹喔啉二酮衍生物或其盐，含有该衍生物或盐的NMDA-甘氨酸受体和/或AMPA受体拮抗剂或红藻氨酸神经毒性抑制剂。 此外，包含所述化合物和药学上可接受的载体的药物组合物：其中取代基如说明书中所述。

公开(公告)号：US5467221A

公开(公告)日：1995-11-14

申请号：US290146

申请日：1994-08-15

申请人： Yoshiaki Iwahara ,  Shoji Kuroda ,  Shuichi Sakamoto ,  Masanori Ogino

发明人： Yoshiaki Iwahara ,  Shoji Kuroda ,  Shuichi Sakamoto ,  Masanori Ogino

IPC分类号： G03B21/02 ,  G03B21/10 ,  G03B21/62 ,  H04N5/74 ,  G03B21/56

CPC分类号： G03B21/02 ,  G03B21/10 ,  G03B21/625 ,  H04N9/3147

摘要： A multi-screen projector having unit module projectors stacked at two higher and lower stages, each unit module projector having a screen with a Fresnel sheet unit, a prism sheet unit, and a lenticular sheet unit. By the functions of the Fresnel sheet unit and the prism sheet unit, main output light from higher and lower screens is converged to substantially the same target point. Only one type of metal molds is required for the Fresnel sheet unit as well as the prism sheet unit, thereby reducing the manufacturing cost of the multi-screen projector.

摘要翻译： 一种具有堆叠在两个较高和较低阶段的单元模块投影仪的多屏幕投影仪，每个单元模块投影仪具有带菲涅耳片单元的屏幕，棱镜片单元和透镜片单元。 通过菲涅耳片单元和棱镜片单元的功能，来自上下屏幕的主输出光会聚到大致相同的目标点。 菲涅耳片单元和棱镜片单元仅需要一种类型的金属模具，从而降低多屏幕投影仪的制造成本。