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1.发明申请Method and apparatus for inspiratory muscle stimulation using implantable device 有权使用可植入装置吸气肌肉刺激的方法和装置公开(公告)号：US20090062882A1
公开(公告)日：2009-03-05
申请号：US11895999
申请日：2007-08-28
申请人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth Beck , Kent Lee , Jonathan Kwok , Zheng Lin
发明人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth Beck , Kent Lee , Jonathan Kwok , Zheng Lin
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61N1/0558
摘要： An inspiratory muscle stimulation system uses an implantable medical device to deliver stimulation to control diaphragmatic contractions for slower and deeper breathing, thereby conditioning and strengthening inspiratory muscles. In various embodiments, respiratory and/or cardiac performance are monitored for controlling parameters of the stimulation.
摘要翻译： 吸气肌肉刺激系统使用可植入医疗装置来输送刺激以控制膈肌收缩以减慢和深呼吸，从而调节和加强吸气肌肉。 在各种实施例中，监测呼吸和/或心脏性能以控制刺激的参数。
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2.发明授权Method and apparatus for inspiratory muscle stimulation using implantable device 有权使用可植入装置吸气肌肉刺激的方法和装置公开(公告)号：US08914113B2
公开(公告)日：2014-12-16
申请号：US13412282
申请日：2012-03-05
申请人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth C. Beck , Kent Lee , Jonathan Kwok , Zheng Lin
发明人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth C. Beck , Kent Lee , Jonathan Kwok , Zheng Lin
CPC分类号： A61N1/3601 , A61N1/0558
摘要： An inspiratory muscle stimulation system uses an implantable medical device to deliver stimulation to control diaphragmatic contractions for slower and deeper breathing, thereby conditioning and strengthening inspiratory muscles. In various embodiments, respiratory and/or cardiac performance are monitored for controlling parameters of the stimulation.
摘要翻译： 吸气肌肉刺激系统使用可植入医疗装置来输送刺激以控制膈肌收缩以减慢和深呼吸，从而调节和加强吸气肌肉。 在各种实施例中，监测呼吸和/或心脏性能以控制刺激的参数。
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3.发明授权Method and apparatus for inspiratory muscle stimulation using implantable device 有权使用可植入装置吸气肌肉刺激的方法和装置公开(公告)号：US08135471B2
公开(公告)日：2012-03-13
申请号：US11895999
申请日：2007-08-28
申请人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth C. Beck , Kent Lee , Jonathan Kwok , Zheng Lin
发明人： Yi Zhang , Shantha Arcot-Krishnamurthy , Lili Liu , Kenneth C. Beck , Kent Lee , Jonathan Kwok , Zheng Lin
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61N1/0558
摘要： An inspiratory muscle stimulation system uses an implantable medical device to deliver stimulation to control diaphragmatic contractions for slower and deeper breathing, thereby conditioning and strengthening inspiratory muscles. In various embodiments, respiratory and/or cardiac performance are monitored for controlling parameters of the stimulation.
摘要翻译： 吸气肌肉刺激系统使用可植入医疗装置来输送刺激以控制膈肌收缩以减慢和深呼吸，从而调节和加强吸气肌肉。 在各种实施例中，监测呼吸和/或心脏性能以控制刺激的参数。
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公开(公告)号：US20100121402A1
公开(公告)日：2010-05-13
申请号：US12615050
申请日：2009-11-09
申请人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
发明人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/3688
摘要： Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing. A method and device for applying reverse hysteresis and mode switching to the delivery of such cardioprotective pacing are described.
摘要翻译： 心脏保护性预激发起搏可用于以导致同步收缩的方式对起搏脉冲递送的特定心肌区域应力或去应激。 这种异常收缩负责预激励起搏的所需心脏保护作用。 描述了一种用于将逆向滞后和模式切换应用于这种心脏保护起搏的递送的方法和装置。
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公开(公告)号：US08929983B2
公开(公告)日：2015-01-06
申请号：US12615050
申请日：2009-11-09
申请人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
发明人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
CPC分类号： A61N1/3627 , A61N1/3688
摘要： Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing. A method and device for applying reverse hysteresis and mode switching to the delivery of such cardioprotective pacing are described.
摘要翻译： 心脏保护性预激发起搏可用于以导致同步收缩的方式对起搏脉冲递送的特定心肌区域应力或去应激。 这种异常收缩负责预激励起搏的所需心脏保护作用。 描述了一种用于将逆向滞后和模式切换应用于这种心脏保护起搏的递送的方法和装置。
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公开(公告)号：US20110040201A1
公开(公告)日：2011-02-17
申请号：US12911233
申请日：2010-10-25
申请人： Yanchuan Pu , Kent Lee , Jonathan Kwok , Zheng Lin
发明人： Yanchuan Pu , Kent Lee , Jonathan Kwok , Zheng Lin
IPC分类号： A61B5/08
CPC分类号： A61B5/0816 , A61B5/4818 , A61N1/3601
摘要： Systems and methods are directed to evaluating breathing disorders, such as periodic disordered breathing. A signal representative of patient respiration is developed, typically patient-internally. An envelope of the signal is provided. Periodicity of the envelope is detected, and presence and severity of periodic disordered breathing is determined based on the periodicity of the envelope.
摘要翻译： 系统和方法旨在评估呼吸障碍，例如周期性无序呼吸。 开发代表患者呼吸的信号，通常是患者内部的。 提供信号的包络。 检测到信封的周期，并根据信封的周期确定定期无序呼吸的存在和严重性。
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公开(公告)号：US20090099621A1
公开(公告)日：2009-04-16
申请号：US12249842
申请日：2008-10-10
申请人： Zheng Lin , Kenneth C. Beck , Jonathan Kwok , Kent Lee , Yachuan Pu , Jeffrey E. Stahmann
发明人： Zheng Lin , Kenneth C. Beck , Jonathan Kwok , Kent Lee , Yachuan Pu , Jeffrey E. Stahmann
IPC分类号： A61N1/36
CPC分类号： A61N1/3611 , A61B5/0816 , A61N1/3601
摘要： A system and method for treating and/or preventing is described for treating periodic breathing characterized by cyclical hyperventilation and hypoventilation, examples of which include Cheyne-Stokes respiration and central sleep apnea. The system could also be used in the treatment of other conditions involving an impairment of respiratory drive.
摘要翻译： 描述了治疗和/或预防的系统和方法，用于治疗以循环过度换气和通气不足为特征的周期性呼吸，其实例包括Cheyne-Stokes呼吸和中枢性睡眠呼吸暂停。 该系统也可用于治疗涉及呼吸驱动障碍的其他病症。
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公开(公告)号：US20070239057A1
公开(公告)日：2007-10-11
申请号：US11392365
申请日：2006-03-29
申请人： Yanchuan Pu , Kent Lee , Jonathan Kwok , Zheng Lin
发明人： Yanchuan Pu , Kent Lee , Jonathan Kwok , Zheng Lin
IPC分类号： A61B5/08
CPC分类号： A61B5/0816 , A61B5/4818 , A61N1/3601
摘要： Systems and methods are directed to evaluating breathing disorders, such as periodic disordered breathing. A signal representative of patient respiration is developed, typically patient-internally. An envelope of the signal is provided. Periodicity of the envelope is detected, and presence and severity of periodic disordered breathing is determined based on the periodicity of the envelope.
摘要翻译： 系统和方法旨在评估呼吸障碍，例如周期性无序呼吸。 开发代表患者呼吸的信号，通常是患者内部的。 提供信号的包络。 检测到信封的周期，并根据信封的周期确定定期无序呼吸的存在和严重性。
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公开(公告)号：US08428711B2
公开(公告)日：2013-04-23
申请号：US12249842
申请日：2008-10-10
申请人： Zheng Lin , Kenneth C. Beck , Jonathan Kwok , Kent Lee , Yachuan Pu , Jeffrey E. Stahmann
发明人： Zheng Lin , Kenneth C. Beck , Jonathan Kwok , Kent Lee , Yachuan Pu , Jeffrey E. Stahmann
IPC分类号： A61N1/00
CPC分类号： A61N1/3611 , A61B5/0816 , A61N1/3601
摘要： A system and method for treating and/or preventing is described for treating periodic breathing characterized by cyclical hyperventilation and hypoventilation, examples of which include Cheyne-Stokes respiration and central sleep apnea. The system could also be used in the treatment of other conditions involving an impairment of respiratory drive.
摘要翻译： 描述了治疗和/或预防的系统和方法，用于治疗以循环过度换气和通气不足为特征的周期性呼吸，其实例包括Cheyne-Stokes呼吸和中枢性睡眠呼吸暂停。 该系统也可用于治疗涉及呼吸驱动障碍的其他病症。
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公开(公告)号：US07819816B2
公开(公告)日：2010-10-26
申请号：US11392365
申请日：2006-03-29
申请人： Yanchuan Pu , Kent Lee , Jonathan Kwok , Zheng Lin
发明人： Yanchuan Pu , Kent Lee , Jonathan Kwok , Zheng Lin
CPC分类号： A61B5/0816 , A61B5/4818 , A61N1/3601
摘要： Systems and methods are directed to evaluating breathing disorders, such as periodic disordered breathing. A signal representative of patient respiration is developed, typically patient-internally. An envelope of the signal is provided. Periodicity of the envelope is detected, and presence and severity of periodic disordered breathing is determined based on the periodicity of the envelope.
摘要翻译： 系统和方法旨在评估呼吸障碍，例如周期性无序呼吸。 开发代表患者呼吸的信号，通常是患者内部的。 提供信号的包络。 检测到信封的周期，并根据信封的周期确定定期无序呼吸的存在和严重性。
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