公开(公告)号：US3967950A

公开(公告)日：1976-07-06

申请号：US477930

申请日：1974-06-10

申请人： Saburo Kano ,  Osami Nomura ,  Yoshihiko Hirono ,  Hisao Ishikawa ,  Shozo Yamada

发明人： Saburo Kano ,  Osami Nomura ,  Yoshihiko Hirono ,  Hisao Ishikawa ,  Shozo Yamada

IPC分类号： A01N47/36 ,  C07D277/82 ,  A01N9/22

CPC分类号： C07D277/82

摘要： Benzothiazole derivatives of the general formula: ##SPC1##Wherein R is chlorine atom, alkyl having from 1 to 4 carbon atoms or methoxy; are useful as selective herbicide.

摘要翻译： 以下通式的苯并噻唑衍生物：

公开(公告)号：US3967951A

公开(公告)日：1976-07-06

申请号：US438475

申请日：1974-01-31

申请人： Yoshihiko Hirono ,  Hisao Ishikawa ,  Shozo Yamada ,  Saburo Kano ,  Osami Nomura

发明人： Yoshihiko Hirono ,  Hisao Ishikawa ,  Shozo Yamada ,  Saburo Kano ,  Osami Nomura

IPC分类号： A01N47/36 ,  C07D277/72 ,  C07D277/82 ,  A01N9/12

CPC分类号： C07D277/72 ,  C07D277/82

摘要： A selective herbicidal composition comprising an effective amount of a compound of the formula ##SPC1##Wherein R is selected from the group consisting of isopropyl and tertbutyl.

摘要翻译： 一种选择性除草组合物，其包含有效量的式WHEREIN R化合物选自异丙基和叔丁基。

公开(公告)号：US3989504A

公开(公告)日：1976-11-02

申请号：US592911

申请日：1975-07-03

申请人： Mikio Sawaki ,  Isao Iwataki ,  Yoshihiko Hirono ,  Hisao Ishikawa ,  Shozo Yamada ,  Yasushi Yasuda ,  Mitsuo Asada

发明人： Mikio Sawaki ,  Isao Iwataki ,  Yoshihiko Hirono ,  Hisao Ishikawa ,  Shozo Yamada ,  Yasushi Yasuda ,  Mitsuo Asada

IPC分类号： C07D309/36

CPC分类号： C07D309/36

摘要： A compound of the formula ##SPC1##Wherein X is hydrogen or halogen:R.sub.1 is alkyl having six or less carbon atoms or phenyl;R.sub.2 is alkyl having 1 to 20 carbon atoms or haloalkyl having six or less carbon atoms or phenyl or phenyl substituted with halogene or nitro or benzyl or phenoxymethyl or 2-phenylvinyl;R.sub.3 is hydrogen or alkyl having 1 to 10 carbon atoms or alkenyl having six or less carbon atoms or alkynyl having six or less carbon atoms or benzyl; a proviso that R.sub.1 and R.sub.2 do not simultaneously represent a methyl group,Is useful as herbicide.

摘要翻译： 式+ q，10的化合物，其中X是氢或卤素：

公开(公告)号：US4259105A

公开(公告)日：1981-03-31

申请号：US33682

申请日：1979-04-26

申请人： Kuniyasu Maeda ,  Minoru Kaeriyama ,  Nobuo Matsui ,  Hisao Ishikawa ,  Shozo Yamada ,  Susumu Okunuki

发明人： Kuniyasu Maeda ,  Minoru Kaeriyama ,  Nobuo Matsui ,  Hisao Ishikawa ,  Shozo Yamada ,  Susumu Okunuki

IPC分类号： A01N33/10 ,  A01N39/02 ,  A01P13/00 ,  A01N37/10 ,  C07C79/46

CPC分类号： A01N39/02

摘要： Compounds of the general formula ##STR1## wherein X is trifluoromethyl or halogen,R.sub.1 is hydrogen, lower alkyl, lower alkenyl or benzyl,R.sub.2 is lower alkyl,R.sub.3 is hydrogen, alkyl or alkali metal,Y is oxygen or sulfur, andn is 0, 1 or 2;are useful as herbicides.

摘要翻译： 通式“IMAGE”的化合物，其中X是三氟甲基或卤素，R 1是氢，低级烷基，低级烯基或苄基，R 2是低级烷基，R 3是氢，烷基或碱金属，Y是氧或硫，n是 0,1或2; 可用作除草剂。

公开(公告)号：US3972899A

公开(公告)日：1976-08-03

申请号：US414300

申请日：1973-11-09

申请人： Mikio Sawaki ,  Isao Iwataki ,  Hisao Ishikawa ,  Shozo Yamada ,  Yasushi Yasuda

发明人： Mikio Sawaki ,  Isao Iwataki ,  Hisao Ishikawa ,  Shozo Yamada ,  Yasushi Yasuda

IPC分类号： C07D309/38 ,  A01N9/20

摘要： Compounds of the formula ##SPC1##Wherein R.sub.1 and R.sub.2 are alkyl having 2 to 6 carbon atoms or phenyl; R.sub.3 is alkyl having 1 to 10 carbon atoms, alkenyl or alkynyl having up to six carbon atoms; R is alkyl of 1 to 20 carbon atoms, phenyl or phenyl substituted with halogen, methyl, methoxy or nitro; and A is carbonyl or sulfonyl, are effective as herbicides, plant growth regulators and fungicides.

摘要翻译： 式WHEREIN R 1和R 2的化合物是具有2至6个碳原子的烷基或苯基; R3是具有1至10个碳原子的烷基，具有至多6个碳原子的烯基或炔基; R为1-20个碳原子的烷基，苯基或被卤素，甲基，甲氧基或硝基取代的苯基; A为羰基或磺酰基，作为除草剂，植物生长调节剂和杀真菌剂有效。

公开(公告)号：US4482740A

公开(公告)日：1984-11-13

申请号：US453499

申请日：1982-12-27

申请人： Isao Iwataki ,  Akira Nakayama ,  Minoru Kaeriyama ,  Hisao Ishikawa ,  Hideo Hosaka ,  Kenichi Kohara ,  Shozo Yamada

发明人： Isao Iwataki ,  Akira Nakayama ,  Minoru Kaeriyama ,  Hisao Ishikawa ,  Hideo Hosaka ,  Kenichi Kohara ,  Shozo Yamada

IPC分类号： A01N35/10 ,  A01N37/02 ,  A01N37/06 ,  A01N37/10 ,  A01N37/50 ,  A01N41/06 ,  A01N41/10 ,  A01N47/20 ,  A01N47/30 ,  C07C67/00 ,  C07C301/00 ,  C07C303/40 ,  C07C311/08 ,  C07C143/75 ,  C07F1/08

CPC分类号： A01N47/30 ,  A01N35/10 ,  A01N37/02 ,  A01N37/06 ,  A01N37/10 ,  A01N37/50 ,  A01N41/06 ,  A01N41/10 ,  A01N47/20

摘要： A compound having the general formula ##STR1## wherein R.sub.1 is ethyl or allyl; andR.sub.2 is alkyl having 1-4 carbon atoms;and a metal salt of the compound defined herein above.The compound is useful as herbicides.

摘要翻译： 具有通式的化合物，其中R 1是乙基或烯丙基; R2是具有1-4个碳原子的烷基; 和上文定义的化合物的金属盐。 该化合物可用作除草剂。

公开(公告)号：US20120232103A1

公开(公告)日：2012-09-13

申请号：US13419691

申请日：2012-03-14

申请人： Masakazu FUKUSHIMA ,  Shozo Yamada ,  Ryo Oyama

发明人： Masakazu FUKUSHIMA ,  Shozo Yamada ,  Ryo Oyama

IPC分类号： A61K31/513 ,  A61P35/00 ,  C07D401/14

CPC分类号： C07D401/14 ,  Y02P20/55

摘要： The present invention provides a novel antimetabolic anticancer agent that has an excellent balance between antitumor effect and toxicity. Specifically, the present invention provides a medicament containing, as an active ingredient, a 5-fluorouracil derivative represented by Formula (I) or a salt thereof: wherein R1 represents a hydrogen atom or a protecting group of a hydroxy group, R2 represents a lower alkoxy-lower alkyl group or a tetrahydrofuranyl group, X represents a carbon atom or a nitrogen atom, and Y represents a halogen atom or a cyano group.

摘要翻译： 本发明提供了抗肿瘤效果和毒性之间具有优异平衡性的新型抗代谢抗癌剂。 具体而言，本发明提供含有作为活性成分的式（I）表示的5-氟尿嘧啶衍生物或其盐的药物：其中，R1表示氢原子或羟基的保护基，R2表示低级 烷氧基 - 低级烷基或四氢呋喃基，X表示碳原子或氮原子，Y表示卤素原子或氰基。

公开(公告)号：US4898939A

公开(公告)日：1990-02-06

申请号：US316632

申请日：1989-02-28

申请人： Sigeru Torii ,  Hideo Tanaka ,  Motoaki Tanaka ,  Shozo Yamada ,  Akira Nakai

发明人： Sigeru Torii ,  Hideo Tanaka ,  Motoaki Tanaka ,  Shozo Yamada ,  Akira Nakai

IPC分类号： C07D499/87 ,  C07D499/00 ,  C07D499/86 ,  C07D499/897 ,  C07D521/00

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D499/00 ,  Y02P20/55

摘要： A process for preparing a 2.beta.-substituted-methylpenicillin compound of the formula ##STR1## wherein --N Y is an optionally substituted heterocyclic group containing 2 to 4 nitrogen atoms as the hetero atom in the ring structure, and R.sub.1 is a penicillin carboxyl protecting group, the process comprising reacting an azetidinonedisulfide compound of the formula ##STR2## wherein R.sub.1 is as defined above and R is a substituted or unsubstituted heterocyclic group with a nitrogen-containing heterocyclic compound of the formula ##STR3## wherein ##STR4## is as defined above in the presence of a metal compound.

公开(公告)号：USD474391S1

公开(公告)日：2003-05-13

申请号：US29156788

申请日：2002-03-06

申请人： Stephen J. Padden ,  Shozo Yamada

设计人： Stephen J. Padden ,  Shozo Yamada

公开(公告)号：US4895941A

公开(公告)日：1990-01-23

申请号：US316631

申请日：1989-02-28

申请人： Sigeru Torii ,  Hideo Tanaka ,  Motoaki Tanaka ,  Shozo Yamada ,  Akira Nakai

发明人： Sigeru Torii ,  Hideo Tanaka ,  Motoaki Tanaka ,  Shozo Yamada ,  Akira Nakai

IPC分类号： C07D499/87 ,  C07D499/00 ,  C07D499/04 ,  C07D499/21 ,  C07D499/86 ,  C07D499/861 ,  C07D499/897

CPC分类号： C07D499/00 ,  Y02P20/55

摘要： 2.alpha.-Methyl-2.beta.-(1,2,3-triazol-1-yl)methylpenam-3.alpha.-carboxylic acid derivatives are prepared by reacting a penicillanic acid sulfoxide derivative of the formula ##STR1## wherein R is a penicillin carboxyl protecting group, and R.sub.1 is hydrogen or halogen, R.sub.2 is hydrogen, lower alkyl or the like with a triazole derivative of the formula ##STR2## wherein R.sub.3 and R.sub.4 are hydrogen, trialkylsilyl, lower alkyl, lower alkoxy or the like and R.sub.5 is hydrogen or silyl substituted with 3 groups selected from the class consisting of lower alkyl, benzyl and phenyl in a solvent.