摘要:
Disclosed herein are optically active biphenol derivatives represented by the following formulas (1) and (2), a method for optically resolving a biphenol derivative represented by formula (2′), a production method of an optically active biphenol derivative (1) comprising a step for reacting a Brønsted acid with a biphenol derivative (2), and a production method of an optically active biphenol derivative (3) comprising a step for reacting a Lewis acid with an optically active biphenol derivative (1) or an optically active biphenol derivative (2).
摘要:
An optically active 2,2′-biphenol derivative and a production method that enables simple and efficient production of this compound. More specifically, an optically active biphenol derivative represented by the following formulas (1) and (2), a method for optically resolving a biphenol derivative represented by formula (2′), a production method of an optically active biphenol derivative (1) comprising a step for reacting a Brønsted acid with a biphenol derivative (2), and a production method of an optically active biphenol derivative (3) comprising a step for reacting a Lewis acid with an optically active biphenol derivative (1) or an optically active biphenol derivative (2). In the following formulas, R represents, for example, a primary or secondary alkyl group having 1 to 10 carbon atoms, * represents an axially asymmetric center, X represents a halogen atom, and R2 represents a tertiary alkyl group having 4 to 6 carbon atoms.
摘要:
It is to provide a novel optically active dibenzazepine derivative having a high utility value as an asymmetric phase-transfer catalyst. It is an optically active 6,7-dihydro-5H-dibenzo[c,e]azepine derivative represented by the following formula (1′), (wherein R represents a divalent organic group for cross-linking the 1st position and the 11th position; R1 and R2 are the same or different, and represent a hydrogen atom, halogen atom, or organic group, or R1 and R2 together represent a divalent organic group; R3′and R4′ are the same or different and represent a monovalent organic group, or R3′ and R4′ together form an organic group that forms a cyclic structure comprising an onium nitrogen atom; Ar represents a monovalent organic group; * represents optical activity, i.e., that one axially asymmetric isomer is present in excess of the other axially asymmetric isomer with respect to a bond axis that constitutes the biphenyl structure of the compound; and X− represents a counter anion).
摘要翻译:提供作为不对称相转移催化剂的具有高效用价值的新颖的光学活性二苯并氮杂衍生物。 它是由下式(1')表示的光学活性的6,7-二氢-5H-二苯并[c,e]吖庚因衍生物,其中R表示用于交联第1位和第11位的二价有机基 R 1和R 2相同或不同,表示氢原子,卤素原子或有机基团,或者R 1和R 2一起表示二价有机基团; R 3'和R 4'相同或不同,表示一价有机基团 或R3'和R4'一起形成形成包含鎓氮原子的环状结构的有机基团; Ar表示一价有机基团; *表示光学活性,即一种轴向不对称异构体存在于另一种轴向 相对于构成化合物的联苯结构的键轴的不对称异构体; X-表示抗衡阴离子)。
摘要:
It is to provide a novel optically active dibenzazepine derivative having a high utility value as an asymmetric phase-transfer catalyst. It is an optically active 6,7-dihydro-5H-dibenzo[c,e]azepine derivative represented by the following formula (1′), (wherein R represents a divalent organic group for cross-linking the 1st position and the 11th position; R1 and R2 are the same or different, and represent a hydrogen atom, halogen atom, or organic group, or R1 and R2 together represent a divalent organic group; R3′ and R4′ are the same or different and represent a monovalent organic group, or R3′ and R4′ together form an organic group that forms a cyclic structure comprising an onium nitrogen atom; Ar represents a monovalent organic group; * represents optical activity, i.e., that one axially asymmetric isomer is present in excess of the other axially asymmetric isomer with respect to a bond axis that constitutes the biphenyl structure of the compound; and X− represents a counter anion).
摘要:
Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt thereof; a hydrate of the derivative or the salt; and a solvate of the derivative or the salt. (In the formula, R1 and R2 may be the same or different and each represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a lower alkoxy group, a haloalkyl group, a haloalkoxy group, an alkylsulfanyl group, an alkylsulfinyl group, an alkylsulfonyl group, a lower alkyl-substituted carbamoyl group, a saturated nitrogen-containing heterocyclic N-carbonyl group, a halogen atom, a cyano group or a hydrogen atom; R3 represents a lower alkyl group, a haloalkyl group, a halogen atom, a hydroxy group or a hydrogen atom; and X represents a sulfur atom, an —S(═O)— group or an —S(═O)2— group.)
摘要:
A novel ruthenium compound that is useful as an asymmetric reduction catalyst for carbonyl compounds. The ruthenium compound of the present invention is represented by a formula (I): (Ru(X)2(Pxx)[R1R2C(NH2)—R3R4C(NH2)] (I)), and when this compound is used as an asymmetric reduction catalyst, an optically active aminoalcohol compound can be produced from an α-aminoketone, and particularly a compound represented by formula (IV), with high stereoselectivity and high yield.
摘要:
A novel ruthenium compound that is useful as an asymmetric reduction catalyst for carbonyl compounds. The ruthenium compound of the present invention is represented by a formula (I): (Ru(X)2(Pxx)[R1R2C(NH2)—R3R4C(NH2)] (I)), and when this compound is used as an asymmetric reduction catalyst, an optically active aminoalcohol compound can be produced from an α-aminoketone, and particularly a compound represented by formula (IV), with high stereoselectivity and high yield.
摘要:
Stress exerted on a liquid crystal display element via a case was likely to impede display on the liquid crystal display element, or damage a liquid crystal display device. A front end of a rib 9 protruding toward a case 1 from a peripheral edge portion of a holder 8 supporting a liquid crystal display element 4 is brought into contact with the case 1, whereby stress on the case 1 is imposed on the rib 9. Thus, stress directly acting on the liquid crystal display element 4 via a rubber sheet 7 can be prevented.
摘要:
The present invention is to provide 2,3-dihalogeno-6-trifluoromethylbenzene derivatives represented by a general formula [I]; ##STR1## wherein X.sub.1 and X.sub.2 are the same or different and each independently represents fluoro or chloro; Y represents COOH, CONH.sub.2, CN, CHO, CH.dbd.NOH or COOR', wherein R' is C.sub.1 -C.sub.4 alkyl, except the case that X.sub.1 and X.sub.2 are each chloro and Y is COOH, which are useful as the starting materials for producing pesticides, drugs and the like, and a process for producing such derivatives.
摘要:
A portable phone incorporating an opening and closing mechanism comprises a main body, a sub-body, a hinge unit, and distribution cables. The main body and the sub-body respectively include electric circuits. The hinge unit includes a shaft disposed at one end of the sub-body, a cam having a center axis coupled to the shaft and used for regulating opening and closing angles of the sub-body, and a pair of leaf springs for maintaining turning angles of the cam. The distribution cables are connected to the electric circuits, and have their center portions wound around the shaft of the hinge unit. The distribution cables are stretched or compressed when the sub-body is opened or closed.