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7 条记录 (耗时 0.02 秒)

    Heat exchanger
    4.
    发明授权
    Heat exchanger 失效
    热交换器

    公开(公告)号：US6155338A

    公开(公告)日：2000-12-05

    申请号：US849916

    申请日：1997-05-29

    申请人： Tsuneo Endou ,  Tsutomu Takahashi ,  Hideyuki Yanai ,  Toshiki Kawamura ,  Tokiyuki Wakayama

    发明人： Tsuneo Endou ,  Tsutomu Takahashi ,  Hideyuki Yanai ,  Toshiki Kawamura ,  Tokiyuki Wakayama

    IPC分类号： F28D9/00 ,  F28F3/04

    CPC分类号： F28F3/044 ,  F28D9/0025 ,  Y10S165/399

    摘要： First heat transfer plates S1 and second heat transfer plates S2 folded along crest folding lines L1 and valley folding lines L2 are bonded to an inner periphery of an outer casing 6 and an outer periphery of an inner casing 7, so that the first and second heat transfer plates S1 and S2 are disposed radiately, thereby forming combustion gas passages and air passages circumferentially alternately. One end of both the combustion gas passages and the air passages is cut into an angle shape, and one side and the other side of the angle shape are closed to form combustion gas passage inlets 11 and air passage outlets 16. In a similar manner, combustion gas passage outlets 12 and air passage inlets 15 are formed at the other end of the combustion gas passages and the air passages. Thus, it is possible to provide a heat exchanger which has a simple structure and is easy to manufacture, and in which the pressure loss due to bending of flow paths can be suppressed to the minimum.

    摘要翻译： PCT No.PCT / JP96 / 02115 Sec。 371日期1997年5月29日 102（e）日期1997年5月29日PCT提交1996年7月26日PCT公布。 公开号WO97 / 06395 日期1997年2月20日沿顶部折叠线L1和谷折线L2折叠的第一传热板S1和第二传热板S2接合到外壳6的内周和内壳7的外周，使得 第一传热板S1和第二传热板S2被辐射地设置，从而沿周向交​​替地形成燃烧气体通道和空气通道。 燃烧气体通道和空气通道的一端被切割成角度形状，并且角形的一侧和另一侧被关闭以形成燃烧气体通道入口11和空气通道出口16.以类似的方式， 燃烧气体通道出口12和空气通道入口15形成在燃烧气体通道和空气通道的另一端。 因此，可以提供一种结构简单且易于制造的热交换器，并且可以将流路弯曲引起的压力损失抑制在最小限度。

    Heat exchanger
    5.
    发明授权
    Heat exchanger 失效
    热交换器

    公开(公告)号：US06209630B1

    公开(公告)日：2001-04-03

    申请号：US09269832

    申请日：1999-04-02

    申请人： Hideyuki Yanai ,  Tadashi Tsunoda

    发明人： Hideyuki Yanai ,  Tadashi Tsunoda

    IPC分类号： F28D900

    CPC分类号： F28D9/0025 ,  F28F9/001 ,  Y10S165/399

    摘要： A heat exchanger which is constructed such that combustion gas passages 4 for passage of combustion gas and air passages 5 for passages of air are arranged alternately, and the heat exchanger is cut at one end side thereof in an unequal angle configuration to form combustion gas passage inlets 11 and air passage outlets 16, and cut at the other end side thereof in an unequal angle configuration to form combustion gas passage outlets 12 and air passage inlets 15. the combustion gas passage inlets 11 and combustion gas passage outlets 12, through which a combustion gas having a larger volume flow rate passes, are formed on a long side of an angle, and the air passage inlets 15 and air passage outlets 16, through which an air having a smaller volume flow rate passes, are formed on a short side of an angle. Accordingly, it is possible to avoid an increase in pressure loss caused by a volume flow rate difference between a high temperature fluid and a low temperature fluid to reduce pressure loss in the entire heat exchanger.

    摘要翻译： 一种热交换器，其构造成使得用于燃烧气体的通过的燃烧气体通道4和用于空气通道的空气通道5交替布置，并且热交换器在其一端侧以不相等的角度构造被切割以形成燃烧气体通道 入口11和空气通道出口16，并且在另一端侧以不相等的角度构造切割，以形成燃烧气体通道出口12和空气通道入口15.燃烧气体通道入口11和燃烧气体通道出口12， 形成具有较大体积流量的燃烧气体在角度较长的一侧上形成，并且空气通道入口15和空气通道出口16通过其中体积流量较小的空气通过， 一个角度 因此，可以避免由高温流体和低温流体之间的体积流量差导致的压力损失的增加，以减少整个热交换器中的压力损失。

    Heat exchanger
    6.
    发明授权
    Heat exchanger 失效
    热交换器

    公开(公告)号：US06192975B1

    公开(公告)日：2001-02-27

    申请号：US09284461

    申请日：1999-06-15

    申请人： Hideyuki Yanai ,  Tadashi Tsunoda ,  Tsuneo Endou ,  Tokiyuki Wakayama

    发明人： Hideyuki Yanai ,  Tadashi Tsunoda ,  Tsuneo Endou ,  Tokiyuki Wakayama

    IPC分类号： F28D102

    CPC分类号： F28F3/044 ,  F28D9/0025

    摘要： First heat-transfer plates S1 and second heat-transfer plates S2 are radially arranged between a larger diameter cylindrical-shaped outer casing 6 and a smaller diameter cylindrical-shaped inner casing 7 to form combustion gas passages 4 and air passages 5 alternately in a circumferential direction, and a multiplicity of projections 22, 23 formed on both surfaces of the first heat-transfer plates S1 and second heat-transfer plates S2 are jointed to one another at tip ends thereof. Pitches P between adjacent projections 22, 23 are changed in a radial direction to make the number of heat transfer units substantially constant in a radial direction to uniformize temperature distributions on the first heat-transfer plates S1 and second heat-transfer plates S2 in the radial direction, thereby avoiding a decrease in heat exchanging efficiency and generation of unwanted thermal stress.

    摘要翻译： 第一传热板S1和第二传热板S2径向地布置在较大直径的圆柱形外壳6和较小直径的圆柱形内壳7之间，以在圆周方向上交替地形成燃烧气体通道4和空气通道5 并且形成在第一传热板S1和第二传热板S2的两个表面上的多个突起22,23在其末端彼此接合。 相邻突起22,23之间的间距P在径向上变化，使得传热单元的数量在径向方向上基本恒定，以使第一传热板S1和第二传热板S2上的温度分布均匀化 方向，从而避免热交换效率的降低和不期望的热应力的产生。

    Inhibitor of HMGB Protein-Mediated Immune Response Activation, and Screening Method
    7.
    发明申请
    Inhibitor of HMGB Protein-Mediated Immune Response Activation, and Screening Method 有权
    HMGB蛋白介导的免疫反应激活抑制剂和筛选方法

    公开(公告)号：US20130183348A1

    公开(公告)日：2013-07-18

    申请号：US13823913

    申请日：2011-09-14

    申请人： Tadatsugu Taniguchi ,  Hideyuki Yanai

    发明人： Tadatsugu Taniguchi ,  Hideyuki Yanai

    IPC分类号： A61K31/7088

    CPC分类号： A61K31/7088 ,  A61K31/7125 ,  C12N15/113 ,  C12N15/117 ,  C12N2310/14 ,  C12N2310/17 ,  C12N2310/315 ,  G01N33/6875 ,  G01N2333/4703 ,  G01N2500/02

    摘要： Provided are an inhibitor of activation of an immune response mediated by an HMGB protein, the inhibitor containing at least one compound selected from the group consisting of a phosphorothioate oligonucleotide and a derivative thereof, and a method of screening for an inhibitor or enhancer of activation of an immune response mediated by an HMGB protein, the method including a mixing step of mixing an HMGB protein and a labeled nucleic acid in the presence and absence of a test substance; a quantifying step of quantifying the HMGB protein bound to the labeled nucleic acid; and a determination step of determining that the test substance is an inhibitor of activation of an immune response mediated by the HMGB protein when the amount of the HMGB protein bound to the labeled nucleic acid in the presence of the test substance is less than the amount of the HMGB protein bound to the labeled nucleic acid in the absence of the test substance and determining that the test substance is an enhancer of activation of an immune response mediated by the HMGB protein when the amount of the HMGB protein bound to the labeled nucleic acid in the presence of the test substance is higher than the amount of the HMGB protein bound to the labeled nucleic acid in the absence of the test substance.

    摘要翻译： 提供了由HMGB蛋白质介导的免疫应答的活化抑制剂，所述抑制剂含有至少一种选自硫代磷酸酯寡核苷酸及其衍生物的化合物，以及筛选抑制剂或增强剂的活化的方法 由HMGB蛋白介导的免疫应答，所述方法包括在存在和不存在测试物质的情况下混合HMGB蛋白和标记的核酸的混合步骤; 量化与标记核酸结合的HMGB蛋白质的量化步骤; 以及确定步骤，当在所述测试物质存在下与所述标记的核酸结合的HMGB蛋白质的量小于所述测试物质的量时，所述测定物质是由所述HMGB蛋白质介导的免疫应答的活化抑制剂 HMGB蛋白在不存在测试物质的情况下与标记的核酸结合，并确定当HMGB蛋白与标记的核酸结合的量的HMGB蛋白的量结合时，测试物质是激活HMGB蛋白介导的免疫应答的增强剂 测试物质的存在高于在不存在测试物质的情况下与标记的核酸结合的HMGB蛋白质的量。