公开(公告)号：US07114403B2

公开(公告)日：2006-10-03

申请号：US10855155

申请日：2004-05-27

申请人： Yuchang Wu ,  Hsiaoho Edward Tung ,  Huiyan Guo ,  Fei Gao ,  Jielin Dai ,  Haipeng Hu

发明人： Yuchang Wu ,  Hsiaoho Edward Tung ,  Huiyan Guo ,  Fei Gao ,  Jielin Dai ,  Haipeng Hu

IPC分类号： G01N1/00

CPC分类号： A61B10/0051 ,  B01L3/0272 ,  B01L3/5029

摘要： The present invention is a device for conveniently collecting and storing liquid samples, as well as applying an aliquot of the sample to a test device, such as a lateral flow immunoassay. The present invention comprises an absorbent swab and a dropper container containing an expression means for expressing the collected sample from the swab. After the collected sample has been expressed into the reservoir of the device, the device is capped. The device can be inverted over a test device, the sides of the reservoir squeezed and an aliquot of the sample applied, in a drop-wise manner, to the sample application well of the test device. The present invention is particularly useful for collecting viscous samples, such as saliva or oral fluid, in a drug of abuse testing setting.

摘要翻译： 本发明是用于方便地收集和储存液体样品的装置，以及将样品的等分试样施加到测试装置，例如横向流动免疫测定。 本发明包括吸收棉签和滴管容器，该容器包含用于从拭子表达所收集的样品的表达装置。 收集的样品已经被表达到设备的储存器中之后，装置被盖上。 该装置可以在测试装置上倒置，储存器的侧面被挤压，并且样品的等分试样以滴下方式施加到测试装置的样品应用井。 本发明特别可用于在滥用试验设备的药物中收集粘性样品，例如唾液或口腔液。

公开(公告)号：US20050106753A1

公开(公告)日：2005-05-19

申请号：US10890540

申请日：2004-07-12

申请人： Yuchang Wu ,  Fei Gao ,  Huiyan Guo

发明人： Yuchang Wu ,  Fei Gao ,  Huiyan Guo

IPC分类号： A61B10/00 ,  B01L3/00 ,  B01L3/02 ,  B01L3/14 ,  G01N20060101 ,  G01N1/10 ,  G01N31/00

CPC分类号： A61B10/0045 ,  A61B10/0051 ,  A61B10/007 ,  A61B10/0096 ,  B01L3/0272 ,  B01L3/5029 ,  B01L3/50825 ,  B01L2300/046 ,  Y10T436/2575

摘要： The present disclosure includes but is not limited to a device for collecting samples, especially liquid samples to be tested for the presence of an analyte, especially for drugs of abuse, antibodies, antigens and biological moieties such as steroids and glucose. In particular, the disclosure describes improvements in collection device design that provide a simple, non-invasive, non-hazardous method of collecting samples from a subject or patient, especially liquid samples such as saliva, oral fluid and urine. The collected sample can be stored in the disclosed device and the device can be used to apply, in a drop-wise manner, an aliquot of the sample directly to a test device.

摘要翻译： 本公开包括但不限于用于收集样品的装置，特别是待测试的液体样品，特别是用于滥用药物，抗体，抗原和生物部分（例如类固醇和葡萄糖）的分析物的存在。 特别地，本公开描述了收集装置设计的改进，其提供从受试者或患者特别是液体样品如唾液，口腔液体和尿液采集样品的简单，非侵入性，非危险的方法。 收集的样品可以存储在所公开的装置中，并且该装置可以用于以逐个方式将样品的等分试样直接应用于测试装置。

公开(公告)号：US20120237923A1

公开(公告)日：2012-09-20

申请号：US13481599

申请日：2012-05-25

申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

IPC分类号： G01N21/78 ,  C12Q1/04 ,  G01N33/566 ,  C12Q1/70

CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

公开(公告)号：US08193002B2

公开(公告)日：2012-06-05

申请号：US12262079

申请日：2008-10-30

申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

IPC分类号： G01N33/53

CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

公开(公告)号：US20090111171A1

公开(公告)日：2009-04-30

申请号：US12262079

申请日：2008-10-30

申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

IPC分类号： C12M1/34

CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

公开(公告)号：US07459314B2

公开(公告)日：2008-12-02

申请号：US10775274

申请日：2004-02-10

申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

IPC分类号： G01N33/53

CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

公开(公告)号：US08828739B2

公开(公告)日：2014-09-09

申请号：US13481599

申请日：2012-05-25

申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

IPC分类号： G01N33/53 ,  G01N33/52

CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

公开(公告)号：USD886907S1

公开(公告)日：2020-06-09

申请号：US29671168

申请日：2018-11-24

申请人： Fei Gao

设计人： Fei Gao

公开(公告)号：US20180110589A1

公开(公告)日：2018-04-26

申请号：US15334499

申请日：2016-10-26

申请人： Fei Gao

发明人： Fei Gao

IPC分类号： A61C7/00 ,  A61C7/08 ,  A61C9/00 ,  A61C13/00

CPC分类号： A61C7/002 ,  A61C7/08 ,  A61C9/0053 ,  A61C13/0004

摘要： The present invention provides an orthodontic process phased into two or more sub-processes for repositioning a patient's teeth. In each sub-process, a complete treatment plan is established, but not all (i.e. only some) appliances in the plan are fabricated to move the teeth, out of the expectation that teeth movement may not completely follow the full course as planned. The entire orthodontic process is thus featured with dynamic planning and incremental implementation of the plans, to address ever-changing treatment profile.

公开(公告)号：US08543234B2

公开(公告)日：2013-09-24

申请号：US12795045

申请日：2010-06-07

申请人： Fei Gao

发明人： Fei Gao

IPC分类号： G06F19/00

CPC分类号： G16H50/50 ,  B33Y50/00 ,  B33Y80/00 ,  G06F19/00

摘要： A method and interactive computer system for dental implant treatment planning, surgical guide design and manufacturing. In the heart of the method is a fully associative workflow integrating image processing, treatment planning, surgical kit configuration and surgical guide CAD/CAM in one single computer system. In this workflow, any changes of image processing parameters and implant information in the earlier stage are automatically propagated to the downstream. This characteristic is referred as associativity. The software aspect of the system is built upon this concept and its corresponding data model. This invention also includes an image processing and geometric modeling approach that is characterized as design for manufacturability and applicability. The integration of treatment planning and surgical guide CAD is further on integrated with manufacturing equipment to constitute a complete CAD/CAM solution, which is also fully associative.

摘要翻译： 一种用于牙种植体治疗计划，外科指南设计和制造的方法和交互式计算机系统。 该方法的核心是在单个计算机系统中整合图像处理，治疗计划，手术套件配置和手术指南CAD / CAM的完全关联工作流程。 在此工作流程中，早期阶段的图像处理参数和植入物信息的任何变化都会自动传播到下游。 这个特征被称为关联性。 系统的软件方面是建立在这个概念和相应的数据模型的基础上的。 本发明还包括以可制造性和适用性为特征的图像处理和几何建模方法。 治疗计划和外科指南CAD的整合进一步与制造设备相结合，构成完整的CAD / CAM解决方案，也是完全相关的。