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公开(公告)号：US06900020B2
公开(公告)日：2005-05-31
申请号：US10257050
申请日：2001-04-09
申请人： Yuichi Ishida , Fumiaki Suzuki , Kazuo Murakami
发明人： Yuichi Ishida , Fumiaki Suzuki , Kazuo Murakami
CPC分类号： C12N9/6486 , A61K38/00 , C07K14/4705 , C12Q1/37 , C12Y304/23015 , G01N2333/96472 , G01N2500/00
摘要： There are provided a method for selection of a substance which is capable of controlling activation of prorenin where an adjusting ability of the activation of prorenin by protein-protein interaction in a profragment region of prorenin as indicator is used; a prorenin activation controlling substance having a function of controlling the activation of prorenin based on protein-protein interaction by a profragment region of prorenin; and hypotensor, organ hypertrophy suppressor and arterial thickening suppressor containing the prorenin activation controlling substance as an effective ingredient.
摘要翻译： 提供了一种选择能够控制肾上腺素能活化的物质的方法，其中使用在作为指示剂的肾上腺素的分段区域中通过蛋白质 - 蛋白质相互作用的蛋白质 - 蛋白质相互作用的调节能力; 具有根据蛋白质 - 蛋白质相互作用的蛋白质 - 蛋白质相互作用控制肾上腺素的活化的功能的肾上腺素能激活控制物质; 和低血压，器官肥大抑制剂和含有作为有效成分的肾上腺素激活控制物质的动脉增厚抑制剂。
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公开(公告)号：US07361637B2
公开(公告)日：2008-04-22
申请号：US11096661
申请日：2005-04-01
申请人： Yuichi Ishida , Fumiaki Suzuki , Kazuo Murakami
发明人： Yuichi Ishida , Fumiaki Suzuki , Kazuo Murakami
IPC分类号： A61K38/00
CPC分类号： C12N9/6486 , A61K38/00 , C07K14/4705 , C12Q1/37 , C12Y304/23015 , G01N2333/96472 , G01N2500/00
摘要： There are provided a method for selection of a substance which is capable of controlling activation of prorenin where an adjusting ability of the activation of prorenin by protein-protein interaction in a profragment region of prorenin as indicator is used; a prorenin activation controlling substance having a function of controlling the activation of prorenin based on protein-protein interaction by a profragment region of prorenin; and hypotensor, organ hypertrophy suppressor and arterial thickening suppressor containing the prorenin activation controlling substance as an effective ingredient.
摘要翻译： 提供了一种选择能够控制肾上腺素能活化的物质的方法，其中使用在作为指示剂的肾上腺素的分段区域中通过蛋白质 - 蛋白质相互作用的蛋白质 - 蛋白质相互作用的调节能力; 具有根据蛋白质 - 蛋白质相互作用的蛋白质 - 蛋白质相互作用控制肾上腺素的活化的功能的肾上腺素能激活控制物质; 和低血压，器官肥大抑制剂和含有作为有效成分的肾上腺素激活控制物质的动脉增厚抑制剂。
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公开(公告)号：US6159723A
公开(公告)日：2000-12-12
申请号：US417305
申请日：1999-10-13
申请人： Kazuo Murakami , Yukio Nakamura , Fumiaki Suzuki , Yuichi Ishida
发明人： Kazuo Murakami , Yukio Nakamura , Fumiaki Suzuki , Yuichi Ishida
CPC分类号： C12N9/6486 , A61K38/00 , A61K39/395 , C07K16/40 , C12Y304/23015 , A61K2300/00
摘要： Disclosed is a novel renin-active substance by utilizing a anti-peptide antibody capable of specifically recognizing a specific amino acid sequence in the human propenin profragment exemplified, as a typical example, by a complex formed from human prorenin and an anti-peptide antibody capable of specifically recognizing an amino acid sequence consisting of at least 15 amino acid residues located within an amino acid sequence consisting of 33 amino acid residues between the isoleucine residue at the 11th site and the arginine residue at the 43rd site within human propenin profragment having an amino acid sequence consisting of 43 amino acid residues.
摘要翻译： 公开了一种新型的肾素活性物质，其通过利用能够特异性识别人丙烯宁胶束中的特定氨基酸序列的抗肽抗体，作为典型实例，通过由人类肾上腺素形成的复合物和抗肽抗体能力 特异性识别由位于第11个位点的异亮氨酸残基之间的33个氨基酸残基的氨基酸序列中的至少15个氨基酸残基的氨基酸序列和人丙烯蛋白碎片中的第43位的精氨酸残基，其具有氨基 酸序列由43个氨基酸残基组成。
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公开(公告)号：US20050203021A1
公开(公告)日：2005-09-15
申请号：US11096661
申请日：2005-04-01
申请人： Yuichi Ishida , Fumiaki Suzuki , Kazuo Murakami
发明人： Yuichi Ishida , Fumiaki Suzuki , Kazuo Murakami
CPC分类号： C12N9/6486 , A61K38/00 , C07K14/4705 , C12Q1/37 , C12Y304/23015 , G01N2333/96472 , G01N2500/00
摘要： There are provided a method for selection of a substance which is capable of controlling activation of prorenin where an adjusting ability of the activation of prorenin by protein-protein interaction in a profragment region of prorenin as indicator is used; a prorenin activation controlling substance having a function of controlling the activation of prorenin based on protein-protein interaction by a profragment region of prorenin; and hypotensor, organ hypertrophy suppressor and arterial thickening suppressor containing the said prorenin activation controlling substance as an effective ingredient.
摘要翻译： 提供了一种选择能够控制肾上腺素能活化的物质的方法，其中使用在作为指示剂的肾上腺素的分段区域中通过蛋白质 - 蛋白质相互作用的蛋白质 - 蛋白质相互作用的调节能力; 具有根据蛋白质 - 蛋白质相互作用的蛋白质 - 蛋白质相互作用控制肾上腺素的活化的功能的肾上腺素能激活控制物质; 以及含有所述血管内皮素激活控制物质作为有效成分的低血压，器官肥大抑制剂和动脉增厚抑制剂。
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公开(公告)号：US5945512A
公开(公告)日：1999-08-31
申请号：US54260
申请日：1998-04-03
IPC分类号： G01N33/53 , A61K39/395 , C07K14/47 , C07K16/18 , C07K16/40 , C07K19/00 , C12N9/64 , G01N33/573 , C07K16/00
CPC分类号： C12N9/6486 , C07K16/40 , C12Y304/23015
摘要： Provided by the present invention are a human prorenin profragment N-terminated peptide antibody capable of specifically recognizing a peptide containing at least 15 amino acid residues from the first leucine residue to the 15th arginine residue in the N-terminated peptide of the human prorenin profragment and a complex of the same with human prorenin. The antibody can be used as a prorenin assay reagent. The human prorenin profragment N-terminated peptide antibody is useful as a reagent for the assay of human prorenin in blood.
摘要翻译： 本发明提供了一种能够特异性识别含有至少15个氨基酸残基的肽的人肾上腺素蛋白片段化N-末端肽抗体，其中人源肾上腺素破坏的N-末端肽中的第一亮氨酸残基至第15位精氨酸残基， 与人类prorenin相同的复合物。 该抗体可用作肾上腺素能测定试剂。 人肾上腺皮质激素N-封端肽抗体可用作血液中人血管内皮素的测定试剂。
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公开(公告)号：US08920596B2
公开(公告)日：2014-12-30
申请号：US12862915
申请日：2010-08-25
申请人： Naoki Mihara , Naoki Matsumoto , Jun Yoshikawa , Kazuo Murakami
发明人： Naoki Mihara , Naoki Matsumoto , Jun Yoshikawa , Kazuo Murakami
IPC分类号： H01L21/3065 , H01J37/32
CPC分类号： H01J37/32192 , C23C16/513 , H01J37/3244 , H01J37/32449
摘要： In a plasma processing apparatus for processing a substrate by plasmatizing a process gas introduced into a processing container, an introducing unit which introduces the process gas is formed on a ceiling surface of the processing container; a gas retention portion which gathers the process gas supplied from the outside of the processing container through a supply passage, and a plurality of gas ejection holes which allow communication between the gas retention portion and the inside of the processing container are formed in the introducing unit; a gas ejection hole is not formed in a location of the gas retention portion that faces an opening of the supply passage; and a cross section of each of the gas ejection holes has a flat shape.
摘要翻译： 在通过对引入到处理容器中的处理气体进行等离子体处理衬底的等离子体处理装置中，在处理容器的顶表面上形成引入处理气体的引入单元; 气体保持部，其通过供给通路收集从处理容器的外部供给的处理气体，并且在导入单元中形成有能够使气体保持部与处理容器内部连通的多个气体喷出孔 ; 在气体保持部的与供给通道的开口相对的位置处不形成气体喷出孔; 并且每个气体喷射孔的横截面具有扁平形状。
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公开(公告)号：US20140242299A1
公开(公告)日：2014-08-28
申请号：US14345148
申请日：2012-09-13
申请人： Masato Okamura , Tetsuo Oosato , Kazuo Murakami , Seiji Yamamoto , Hiroyuki Arai , Hidehiro Urata , Hajime Hirasawa , Osamu Shibasaki , Koji Negishi
发明人： Masato Okamura , Tetsuo Oosato , Kazuo Murakami , Seiji Yamamoto , Hiroyuki Arai , Hidehiro Urata , Hajime Hirasawa , Osamu Shibasaki , Koji Negishi
CPC分类号： C23F11/08 , C23F11/18 , C23F11/185 , C23F15/00 , G21C17/0225 , G21D3/08 , Y02E30/40
摘要： A method for injecting a corrosion inhibitor injecting an oxidant and an anticorrosive agent-pH adjusting agent complex including an anticorrosive agent and a pH adjusting agent adsorbed on a surface of the anticorrosive agent into high temperature water in contact with a surface of a metal structural material and irradiating the high temperature water with a radioactive ray or an ultraviolet ray, wherein the anticorrosive agent of the anticorrosive agent-pH adjusting agent complex has, on the surface of the anticorrosive agent, an active site where the pH adjusting agent reacts with the oxidant, and the pH adjusting agent present on the surface of the anticorrosive agent of the anticorrosive agent-pH adjusting agent complex and/or in the high temperature water is oxidized with the oxidant by the irradiation with the radioactive ray or the ultraviolet ray to change pH adjusting ability of the pH adjusting agent and shift a pH of the high temperature water to a neutral side, and thereby deposition of the anticorrosive agent 11 to the metal structural material 65 is accelerated.
摘要翻译： 一种将注入氧化剂的腐蚀抑制剂和防腐蚀剂 - pH调节剂复合物的方法，所述防腐蚀剂 - pH调节剂复合物包括吸附在防腐剂表面上的耐腐蚀剂和pH调节剂，所述抗腐蚀剂和pH调节剂与金属结构材料表面接触的高温水中 并用放射线或紫外线照射高温水，其中防腐剂 - pH调节剂复合物的防腐剂在防腐剂的表面上具有pH调节剂与氧化剂反应的活性位点 ，并且在抗腐蚀剂 - pH调节剂配合物的防腐剂的表面上和/或在高温水中存在的pH调节剂用氧化剂通过用放射线或紫外线照射而被氧化以改变pH 调节pH调节剂的能力并将高温水的pH值转移到中性侧，从而进行 加速了防锈剂11向金属结构材料65的沉积。
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公开(公告)号：US08757989B2
公开(公告)日：2014-06-24
申请号：US12547759
申请日：2009-08-26
申请人： Kazuo Murakami
发明人： Kazuo Murakami
IPC分类号： F04B35/04
CPC分类号： F04C23/008 , F04C18/0215 , F04C29/0085 , F04C2240/803 , F04C2240/808 , H02K5/225 , H02K11/33
摘要： A motor-driven compressor includes a compression mechanism for compressing refrigerant, an electric motor for driving the compression mechanism, an inverter for controlling the operation of the electric motor, and a motor harness for electrically connecting the electric motor to the inverter. The compression mechanism and the electric motor are mechanically connected each other. The electric motor has first and second coil ends. The first coil end is located on the side of the compression mechanism and the inverter is located on the side of the second coil end. The motor harness is led out from the first coil end.
摘要翻译： 电动压缩机包括用于压缩制冷剂的压缩机构，用于驱动压缩机构的电动机，用于控制电动机的操作的逆变器和用于将电动机电连接到逆变器的电动机线束。 压缩机构和电动机彼此机械连接。 电动机具有第一和第二线圈端部。 第一线圈端位于压缩机构的一侧，并且逆变器位于第二线圈端的一侧。 电动机线束从第一个线圈端引出。
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公开(公告)号：US08162626B2
公开(公告)日：2012-04-24
申请号：US12333982
申请日：2008-12-12
申请人： Hiroshi Fukasaku , Tatsushi Mori , Kazuo Murakami , Masao Iguchi , Masahiro Kawaguchi , Ken Suitou
发明人： Hiroshi Fukasaku , Tatsushi Mori , Kazuo Murakami , Masao Iguchi , Masahiro Kawaguchi , Ken Suitou
CPC分类号： H02K5/10 , F04C18/0215 , F04C23/008 , F04C27/00 , H02K5/12 , H02K7/14 , H02K11/33
摘要： A motor-driven compressor has a compression mechanism, a rotary shaft, an electric motor, a motor drive circuit, a connecting terminal and a housing assembly. The compression mechanism, the electric motor, and the motor drive circuit are disposed along the axial direction of the rotary shaft in the housing assembly having first through third housings. The first housing is used for mounting the electric motor and the compression mechanism. The second housing has a terminal mounting portion for fixing the connecting terminal. The first and second housings have fastening portions at the radially peripheral portion thereof. The third housing is joined to the second housing to form an accommodation space for accommodating the motor drive circuit. The closed casing is formed by fastening the fastening portions of the first and second housings by means of a first bolt and connecting the second housing to the open end of the first housing.
摘要翻译： 电动压缩机具有压缩机构，旋转轴，电动马达，马达驱动电路，连接端子和壳体组件。 压缩机构，电动马达和马达驱动电路沿着具有第一至第三壳体的壳体组件中的旋转轴的轴向设置。 第一壳体用于安装电动机和压缩机构。 第二壳体具有用于固定连接端子的端子安装部。 第一和第二壳体在其径向周向部分处具有紧固部分。 第三壳体连接到第二壳体以形成用于容纳马达驱动电路的容置空间。 封闭的壳体通过借助于第一螺栓紧固第一和第二壳体的紧固部分并将第二壳体连接到第一壳体的开口端而形成。
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公开(公告)号：US20110054171A1
公开(公告)日：2011-03-03
申请号：US12863146
申请日：2009-01-14
IPC分类号： C07D237/34
CPC分类号： C07F9/650947 , C07B57/00
摘要： Salts of optically active [4-(2-diphenylphosphanylnaphthalen-1-yl)phthalazin-1-yl]-(1-phenylethyl)amines represented by the formulas (1) to (4) with an optically active organic sulfonic acid, and a production method thereof.
摘要翻译： 由式（1）〜（4）表示的光学活性的[4-（2-二苯基膦基萘-1-基）二氮杂萘-1-基] - （1-苯基乙基）胺与光学活性的有机磺酸的盐， 生产方法。
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