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公开(公告)号：US09163149B2
公开(公告)日：2015-10-20
申请号：US13807267
申请日：2011-06-30
IPC分类号： A61F2/28 , A61F2/30 , A61L27/30 , C09D5/00 , A61C8/00 , A61K6/00 , A61C5/08 , A61C13/01 , A61C13/08
CPC分类号： C09D5/00 , A61C5/70 , A61C5/73 , A61C5/77 , A61C8/0012 , A61C8/0013 , A61C13/01 , A61C13/08 , A61F2/30767 , A61F2002/3093 , A61K6/0044 , A61L27/303 , A61L2430/02 , A61L2430/12 , Y10T428/31678
摘要： An implant material includes: a base material 10; and a carbonaceous film 20 provided on a surface of the base material 10. The carbonaceous film 20 includes carbon atoms, oxygen atoms, and nitrogen atoms in a surface thereof, and the carbon atoms are bonded to the oxygen atoms to form carboxyl carbon and carbon having a single bond with oxygen. In the surface of the carbonaceous film 20, a content of nitrogen atoms is greater than or equal to 8.0 at. %, a content of carbon having a single bond with oxygen is greater than or equal to 5.4%, and a content of carboxyl carbon is less than or equal to 3.1%.
摘要翻译： 植入材料包括：基材10; 以及设置在基材10的表面上的碳质膜20.碳质膜20的表面含有碳原子，氧原子和氮原子，碳原子与氧原子键合而形成羧基碳和碳 与氧单键。 在碳质膜20的表面，氮原子的含量大于或等于8.0at。 ％，与氧具有单键的碳含量大于或等于5.4％，羧基碳含量小于或等于3.1％。
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公开(公告)号：US20100247917A1
公开(公告)日：2010-09-30
申请号：US12741683
申请日：2008-11-05
申请人： Yuki Nitta , Tatsuyuki Nakatani , Keishi Okamoto
发明人： Yuki Nitta , Tatsuyuki Nakatani , Keishi Okamoto
CPC分类号： C23C16/26 , A61L27/303 , A61L31/084 , A61L2420/02 , C23C16/56 , Y10T428/30
摘要： A targeted carbon thin film is a carbon thin film formed on a surface of a base material. The film includes a carbon framework of carbon atoms bonded together, and an amino group bonded to the carbon atoms forming the carbon framework.
摘要翻译： 目标碳薄膜是形成在基材表面上的碳薄膜。 该膜包括键合在一起的碳原子的碳骨架和与形成碳骨架的碳原子键合的氨基。
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公开(公告)号：US20110318714A1
公开(公告)日：2011-12-29
申请号：US13148928
申请日：2009-02-10
申请人： Hiroki Nikawa , Seichiyou Makihira , Yuichi Mine , Yoshinori Abe , Tatsuyuki Nakatani , Keishi Okamoto , Yuki Nitta
发明人： Hiroki Nikawa , Seichiyou Makihira , Yuichi Mine , Yoshinori Abe , Tatsuyuki Nakatani , Keishi Okamoto , Yuki Nitta
IPC分类号： A61C5/08 , C23C14/34 , A61C5/00 , C04B35/565 , B32B15/04
CPC分类号： A61L27/025 , A61K6/027 , A61L27/303 , A61L27/306 , A61L2420/04 , C23C16/30 , Y10T428/31678
摘要： An implant material includes a base material, and a silicon-containing carbon thin film formed on a surface of the base material. The carbon thin film contains a C—C component in which carbon atoms are bonded, and a SiC component in which carbon and silicon atoms are bonded, and a ratio of the SiC component is 0.06 or higher.
摘要翻译： 植入材料包括基材和形成在基材表面上的含硅碳薄膜。 碳薄膜含有碳原子键合的C-C成分和碳和硅原子键合的SiC成分，SiC成分的比例为0.06以上。
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公开(公告)号：US20130108879A1
公开(公告)日：2013-05-02
申请号：US13807267
申请日：2011-06-30
CPC分类号： C09D5/00 , A61C5/70 , A61C5/73 , A61C5/77 , A61C8/0012 , A61C8/0013 , A61C13/01 , A61C13/08 , A61F2/30767 , A61F2002/3093 , A61K6/0044 , A61L27/303 , A61L2430/02 , A61L2430/12 , Y10T428/31678
摘要： An implant material includes: a base material 10; and a carbonaceous film 20 provided on a surface of the base material 10. The carbonaceous film 20 includes carbon atoms, oxygen atoms, and nitrogen atoms in a surface thereof, and the carbon atoms are bonded to the oxygen atoms to form carboxyl carbon and carbon having a single bond with oxygen. In the surface of the carbonaceous film 20, a content of nitrogen atoms is greater than or equal to 8.0 at. %, a content of carbon having a single bond with oxygen is greater than or equal to 5.4%, and a content of carboxyl carbon is less than or equal to 3.1%.
摘要翻译： 植入材料包括：基材10; 以及设置在基材10的表面上的碳质膜20.碳质膜20的表面含有碳原子，氧原子和氮原子，碳原子与氧原子键合而形成羧基碳和碳 与氧单键。 在碳质膜20的表面，氮原子的含量大于或等于8.0at。 ％，与氧具有单键的碳含量大于或等于5.4％，羧基碳含量小于或等于3.1％。
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公开(公告)号：US08430591B1
公开(公告)日：2013-04-30
申请号：US13402788
申请日：2012-02-22
申请人： Keishi Okamoto , Satoru Ando , Tatsuyuki Nakatani , Yuki Nitta , Kunihiro Toyota , Kouichi Takayama , Takumi Kajiwara , Hirotaka Masuda
发明人： Keishi Okamoto , Satoru Ando , Tatsuyuki Nakatani , Yuki Nitta , Kunihiro Toyota , Kouichi Takayama , Takumi Kajiwara , Hirotaka Masuda
IPC分类号： B43K7/10
摘要： A ballpoint pen tip includes a ball and a ball holder for rotatably holding the ball. The ball includes a ball body and a first carbonaceous film formed so as to cover a surface of the ball body. The first carbonaceous film has carbon atoms and oxygen atoms bonded to some of the carbon atoms. The ratio of carbon atoms bonded to oxygen atoms to the total carbon atoms at a surface of the first carbonaceous film is equal to or greater than 0.1.
摘要翻译： 圆珠笔尖包括球和用于可旋转地保持球的球保持器。 球包括球体和形成为覆盖球体表面的第一碳质膜。 第一碳质膜具有与一些碳原子键合的碳原子和氧原子。 与氧原子键合的碳原子与第一碳质膜表面的总碳原子的比例等于或大于0.1。
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公开(公告)号：US20090005862A1
公开(公告)日：2009-01-01
申请号：US12088000
申请日：2007-01-15
申请人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
发明人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
IPC分类号： A61F2/06
CPC分类号： A61L31/084 , A61F2/91 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L33/025 , A61L2300/416 , A61L2300/606 , A61L2420/08
摘要： A stent includes a tubular stent body 11, a diamond-like carbon film 12 formed on the surface of the stent body 11 and having an activated surface, and a polymer layer 13 immobilized on the surface of the diamond-like carbon film. The polymer layer 13 contains a drug 14 having an effect to prevent restenosis, and the drug 14 is gradually released from the polymer layer 13.
摘要翻译： 支架包括管状支架体11，形成在支架主体11的表面上并具有活化表面的类金刚石碳膜12和固定在金刚石状碳膜表面上的聚合物层13。 聚合物层13含有具有防止再狭窄作用的药物14，药物14从聚合物层13逐渐释放。
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7.发明授权Medical device having diamond-like thin film and method for manufacturing thereof 有权具有类金刚石薄膜的医疗装置及其制造方法公开(公告)号：US07931934B2
公开(公告)日：2011-04-26
申请号：US12301003
申请日：2007-01-15
申请人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Koji Mori , Ikuo Komura
发明人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Koji Mori , Ikuo Komura
CPC分类号： A61L31/088 , A61F2/0077 , A61L31/10 , A61M25/0045 , C08L43/04
摘要： A medical device includes a medial device body, and a diamond-like thin film covering the medical device body and containing silicon. The diamond-like thin film has a concentration of silicon which is lower in a surface thereof than in an interface thereof with the medical device body mentioned above, and continuously varies.
摘要翻译： 医疗装置包括中间装置主体和覆盖医疗装置主体并且含有硅的金刚石状薄膜。 菱形薄膜的表面的硅浓度比上述医疗装置体的界面低，连续变化。
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公开(公告)号：US20110060403A9
公开(公告)日：2011-03-10
申请号：US12088000
申请日：2007-01-15
申请人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
发明人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
IPC分类号： A61F2/06
CPC分类号： A61L31/084 , A61F2/91 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L33/025 , A61L2300/416 , A61L2300/606 , A61L2420/08
摘要： A stent includes a tubular stent body 11, a diamond-like carbon film 12 formed on the surface of the stent body 11 and having an activated surface, and a polymer layer 13 immobilized on the surface of the diamond-like carbon film. The polymer layer 13 contains a drug 14 having an effect to prevent restenosis, and the drug 14 is gradually released from the polymer layer 13.
摘要翻译： 支架包括管状支架体11，形成在支架主体11的表面上并具有活化表面的类金刚石碳膜12和固定在金刚石状碳膜表面上的聚合物层13。 聚合物层13含有具有防止再狭窄作用的药物14，药物14从聚合物层13逐渐释放。
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9.发明申请Method For Treating Surface Of Material, Surface-Treated Material, Medical Material, And Medical Instrument 审中-公开处理材料，表面处理材料，医疗材料和医疗仪器的方法公开(公告)号：US20070207321A1
公开(公告)日：2007-09-06
申请号：US10594918
申请日：2005-03-25
CPC分类号： C23C16/56 , A61F2310/0058 , A61L27/303 , A61L29/103 , A61L31/084 , C01B32/28 , C23C16/26 , Y10T428/31504 , Y10T428/31511 , Y10T428/3154
摘要： A diamond-like carbon film (DLC film) is formed on the surface of a base material made of an inorganic material, such as ceramics, or the like, or an organic material, such as resin, or the like. The surface of the resultant DLC film is treated with plasma, or the like, so as to be activated. Various monomers having biocompatibility, etc., are graft-polymerized to the activated surface of the DLC film, whereby a polymer layer is formed from the monomers grafted to the surface of the DLC film. Thus, the base material coated with the DLC film modified with a polymer which does not readily separate can be realized.
摘要翻译： 在由诸如陶瓷等的无机材料制成的基材的表面上，或诸如树脂等有机材料的表面上形成类金刚石碳膜（DLC膜）。 用等离子体等处理得到的DLC膜的表面，使其活化。 具有生物相容性等的各种单体被接枝聚合到DLC膜的活化表面上，由此由接枝到DLC膜表面的单体形成聚合物层。 因此，可以实现用不易分离的聚合物改性的DLC膜涂覆的基材。
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公开(公告)号：US08435287B2
公开(公告)日：2013-05-07
申请号：US12088000
申请日：2007-01-15
申请人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
发明人： Tatsuyuki Nakatani , Keishi Okamoto , Shuzo Yamashita , Ikuo Komura , Koji Mori
IPC分类号： A61F2/06
CPC分类号： A61L31/084 , A61F2/91 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L33/025 , A61L2300/416 , A61L2300/606 , A61L2420/08
摘要： A stent includes a tubular stent body 11, a diamond-like carbon film 12 formed on the surface of the stent body 11 and having an activated surface, and a polymer layer 13 immobilized on the surface of the diamond-like carbon film. The polymer layer 13 contains a drug 14 having an effect to prevent restenosis, and the drug 14 is gradually released from the polymer layer 13.
摘要翻译： 支架包括管状支架体11，形成在支架主体11的表面上并具有活化表面的类金刚石碳膜12和固定在金刚石状碳膜表面上的聚合物层13。 聚合物层13含有具有防止再狭窄作用的药物14，药物14从聚合物层13逐渐释放。
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