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公开(公告)号：US09925124B2
公开(公告)日：2018-03-27
申请号：US13408050
申请日：2012-02-29
CPC分类号： A61K6/0008 , A61C13/0022 , A61K6/083 , C08L33/10
摘要： Provided is a dental composition comprising a first largest group of particles and resin matrix, wherein the first largest group consists of particles whose particle size ranges from 0.7 to 1.5 times the representative particle size of the first largest fraction in a population of particles included in the composition whose particle size ranges from 110 to 1000 μm; and wherein the ratio of the number of particles included in the first largest group to the number of particles whose particle size ranges from 0.5 to 2.0 times the representative particle size of the first largest fraction is equal to or more than 0.8.
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2.发明申请公开(公告)号：US20130190422A1
公开(公告)日：2013-07-25
申请号：US13408050
申请日：2012-02-29
IPC分类号： A61K6/083
CPC分类号： A61K6/0008 , A61C13/0022 , A61K6/083 , C08L33/10
摘要： Provided is a dental composition comprising a first largest group of particles and resin matrix, wherein the first largest group consists of particles whose particle size ranges from 0.7 to 1.5 times the representative particle size of the first largest fraction in a population of particles included in the composition whose particle size ranges from 110 to 1000 μm; and wherein the ratio of the number of particles included in the first largest group to the number of particles whose particle size ranges from 0.5 to 2.0 times the representative particle size of the first largest fraction is equal to or more than 0.8.
摘要翻译： 本发明提供一种牙科用组合物，其包含第一最大组的颗粒和树脂基质，其中第一大组由颗粒的粒径的0.7至1.5倍的颗粒组成。 粒径范围为110〜1000μm的组合物; 其中，包含在第一大组中的粒子数与粒径在第一最大部分的代表粒径的0.5〜2.0倍的粒子数之比等于或大于0.8。
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公开(公告)号：US08494241B2
公开(公告)日：2013-07-23
申请号：US13569581
申请日：2012-08-08
IPC分类号： G06K9/00
CPC分类号： A61C9/0053 , A61C19/05
摘要： An occlusion evaluation apparatus capable of evaluating a masticatory ability depending on an occlusal geometry of teeth without actually used by a human subject, reads three dimensional data of geometries of maxillary molar teeth 1, 2, 3, 4 and mandibular molar teeth 5, 6, 7, 8, and specifies a geometry of a fluxion space Va defined by a plane Sa which includes two adjacent contact points Pa between the maxillary molar teeth 1, 2, 3, 4 and mandibular molar teeth 5, 6, 7, 8 and which is perpendicular to the occlusal plane, the occlusal surfaces of the maxillary molar teeth 1, 2, 3, 4, and the occlusal surfaces of the mandibular molar teeth 5, 6, 7, 8.
摘要翻译： 一种咬合评价装置，其能够根据牙齿的咬合面几何形状来评价咀嚼能力，而实际上不被人体使用，能够读取上颌牙齿1,2,3,4和下颌牙齿5,6的几何形状的三维数据， 如图7,8所示，并且规定由平面Sa限定的流动空间Va的几何形状，该平面Sa包括上颌齿臼齿1,2,3,4和下颌齿臼齿5,6,7,8之间的两个相邻接触点Pa，并且 垂直于咬合平面，上颌牙齿1,2,3和4的咬合面以及下颌牙摩擦牙5,6,7,8的咬合面。
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4.发明申请OCCLUSAL WEAR EVALUATION APPARATUS AND OCCLUSAL WEAR EVALUATION METHOD 审中-公开OCCLUSAL WEAR EVALUATION装置和OCCLUSAL WEAR EVALUATION方法公开(公告)号：US20130054190A1
公开(公告)日：2013-02-28
申请号：US13589434
申请日：2012-08-20
IPC分类号： G06F15/00
CPC分类号： A61C19/05 , A61C11/00 , A61C13/0004 , A61C19/04 , G16H50/50
摘要： An occlusal wear evaluation apparatus capable of evaluating quantitatively an occlusal wear of a used denture reads three dimensional data of a denture before use and three dimensional data of the denture after use, calculates a difference in a set value of an articulator allowing the maxillary dental arch and the mandibular dental arch of the denture to occlude between the denture before use and the denture after use, by way of simulating movements of a jaw in the articulator with the three dimensional data of the denture before use and the three dimensional data of the denture after use, and indicates the calculated difference.
摘要翻译： 一种咬合磨损评价装置，其能够定量评价使用过的假牙的咬合磨损，在使用前读取义齿的三维数据和使用后的义齿的三维数据，计算允许上颌牙弓的咬合器的设定值的差异 以及义齿下颌牙弓在使用前与义齿之间闭合，并且在使用之后通过假牙的三维数据和假牙的三维数据模拟咬合器中的钳口的运动 使用后，表示计算出的差值。
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公开(公告)号：US20130045458A1
公开(公告)日：2013-02-21
申请号：US13569581
申请日：2012-08-08
IPC分类号： A61C19/05
CPC分类号： A61C9/0053 , A61C19/05
摘要： An occlusion evaluation apparatus capable of evaluating a masticatory ability depending on an occlusal geometry of teeth without actually used by a human subject, reads three dimensional data of geometries of maxillary molar teeth 1, 2, 3, 4 and mandibular molar teeth 5, 6, 7, 8, and specifies a geometry of a fluxion space Va defined by a plane Sa which includes two adjacent contact points Pa between the maxillary molar teeth 1, 2, 3, 4 and mandibular molar teeth 5, 6, 7, 8 and which is perpendicular to the occlusal plane, the occlusal surfaces of the maxillary molar teeth 1, 2, 3, 4, and the occlusal surfaces of the mandibular molar teeth 5, 6, 7, 8.
摘要翻译： 一种咬合评价装置，其能够根据牙齿的咬合面几何形状来评价咀嚼能力，而实际上不被人体使用，能够读取上颌牙齿1,2,3,4和下颌牙齿5,6的几何形状的三维数据， 如图7,8所示，并且规定由平面Sa限定的流动空间Va的几何形状，该平面Sa包括上颌齿臼齿1,2,3,4和下颌齿臼齿5,6,7,8之间的两个相邻接触点Pa，并且 垂直于咬合平面，上颌牙齿1,2,3和4的咬合面以及下颌牙摩擦牙5,6,7,8的咬合面。
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公开(公告)号：US09220663B2
公开(公告)日：2015-12-29
申请号：US13218779
申请日：2011-08-26
CPC分类号： A61K6/06 , A61K6/0005 , A61K6/0008 , A61K6/0058 , A61K6/0094 , A61K6/083 , C08L33/08 , C08L33/10
摘要： There is provided a dental composition comprising at least one kind of filler and resin matrix, wherein the at least one kind of filler comprises a population of particles, wherein the population of particles has an average particle size from 110 to 500 μm, the maximum particle size of the population of particles is less than 1.4 times the average particle size, and the D30 of particle size distribution of the population of particles is no less than 0.9 times the average particle size.
摘要翻译： 提供了包含至少一种填料和树脂基质的牙科用组合物，其中所述至少一种填料包含一群颗粒，其中所述颗粒群平均粒径为110-500μm，最大颗粒 颗粒群的尺寸小于平均粒径的1.4倍，颗粒群粒径分布的D30不小于平均粒径的0.9倍。
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公开(公告)号：US20130030080A1
公开(公告)日：2013-01-31
申请号：US13218779
申请日：2011-08-26
IPC分类号： A61K6/083
CPC分类号： A61K6/06 , A61K6/0005 , A61K6/0008 , A61K6/0058 , A61K6/0094 , A61K6/083 , C08L33/08 , C08L33/10
摘要： There is provided a dental composition comprising at least one kind of filler and resin matrix, wherein the at least one kind of filler comprises a population of particles, wherein the population of particles has an average particle size from 110 to 500 μm, the maximum particle size of the population of particles is less than 1.4 times the average particle size, and the D30 of particle size distribution of the population of particles is no less than 0.9 times the average particle size.
摘要翻译： 提供了包含至少一种填料和树脂基质的牙科用组合物，其中所述至少一种填料包含一群颗粒，其中所述颗粒群平均粒径为110-500μm，最大颗粒 颗粒群的尺寸小于平均粒径的1.4倍，颗粒群粒径分布的D30不小于平均粒径的0.9倍。
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公开(公告)号：US08436004B2
公开(公告)日：2013-05-07
申请号：US12663729
申请日：2008-06-12
申请人： Makoto Bamba , Hidetomo Furuyama , Kenji Niiyama , Toshihiro Sakamoto , Satoshi Sunami , Keiji Takahashi , Fuyuki Yamamoto , Takashi Yoshizumi
发明人： Makoto Bamba , Hidetomo Furuyama , Kenji Niiyama , Toshihiro Sakamoto , Satoshi Sunami , Keiji Takahashi , Fuyuki Yamamoto , Takashi Yoshizumi
IPC分类号： A01N43/90 , A61K31/519 , C07D487/00
CPC分类号： C07D487/04 , A61K31/522 , A61K31/5415 , A61K31/55 , A61K45/06 , C07D519/00
摘要： The invention relates to a compound of a general formula (I): wherein A1 and A2 each mean a nitrogen atom or an optionally-substituted methine group; Ring B means a 5-membered to 7-membered aliphatic ring, or a spiro or bicyclo ring formed from the aliphatic ring and any other 3-membered to 7-membered aliphatic ring; R1 means a hydrogen atom, or an optionally-substituted C1-C6 alkyl group, or an optionally-substituted aryl, aralkyl or heteroaryl group; R2 means an optionally-substituted aryl, aralkyl or heteroaryl group; and X means a group of ═NH or ═O, etc. Based on its excellent Wee1 kinase-inhibitory effect, the compound of the invention has cell growth-inhibitory effect and has an additive/synergistic effect with any other anticancer agent, and is therefore useful in the field of medicine.
摘要翻译： 本发明涉及通式（I）的化合物：其中A1和A2各自表示氮原子或任选取代的次甲基; 环B表示由脂族环和任何其它3元至7元脂肪环形成的5元至7元脂族环或螺环或双环; R 1表示氢原子或任选取代的C 1 -C 6烷基，或任选取代的芳基，芳烷基或杂芳基; R 2表示任选取代的芳基，芳烷基或杂芳基; X表示一组= NH或= O等。基于其优异的Wee1激酶抑制作用，本发明化合物具有细胞生长抑制作用，与任何其他抗癌剂具有添加/协同作用，并且 因此在医学领域是有用的。
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公开(公告)号：US08304356B2
公开(公告)日：2012-11-06
申请号：US13398885
申请日：2012-02-17
IPC分类号： A61C13/083 , A61C13/00 , C03C8/22 , C03C3/091
CPC分类号： C03C3/091 , A61K6/0094 , A61K6/0276 , C03C4/0021 , C03C8/02 , C03C8/14
摘要： The present invention relates to a color adapting composition used for coloring and color adapting porcelain for ceramic crown such as dental restorations and prosthetics, and aluminosilicate glass appropriate for using in a color adapting composition. More specifically, a color adapting composition for dental porcelains are prepared by blending two or more kinds of glass frits having different sintering temperatures from each other and an inorganic pigment or a colored glass obtained by previously dispersing inorganic pigments in glass.
摘要翻译： 本发明涉及一种用于陶瓷冠的着色和着色适应性瓷的修色组合物，例如牙科修复体和假肢，以及适用于适应颜色的组合物的铝硅酸盐玻璃。 更具体地说，通过将两种或更多种具有不同烧结温度的玻璃料混合并将无机颜料或通过预先将无机颜料分散在玻璃中得到的着色玻璃混合来制备用于牙科瓷器的调色组合物。
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公开(公告)号：US20110243891A1
公开(公告)日：2011-10-06
申请号：US13133673
申请日：2009-12-09
申请人： Makoto Bamba , Hidetomo Furuyama , Toshihiro Sakamoto , Satoshi Sunami , Keiji Takahashi , Fuyuki Yamamoto , Takashi Yoshizumi
发明人： Makoto Bamba , Hidetomo Furuyama , Toshihiro Sakamoto , Satoshi Sunami , Keiji Takahashi , Fuyuki Yamamoto , Takashi Yoshizumi
IPC分类号： A61K31/519 , C07D487/04 , A61K31/496 , A61K31/5377 , A61K31/497 , A61K31/664 , A61K31/675 , A61K31/7028 , A61K31/7076 , A61K31/52 , A61K31/7068 , A61K38/12 , A61K33/24 , A61K39/395 , A61K38/21 , A61K31/716 , A61K38/50 , A61K33/36 , A61P35/00
CPC分类号： A61K31/519 , A61K31/5377 , C07D487/04 , C07D519/00
摘要： The present invention relates to a compound of General Formula (I) below, among others. In the Formula, Ar1 is an optionally substituted aryl or heteroaryl group; R1 is a hydrogen atom, an optionally substituted C1-C6 alkyl group, or an optionally substituted aryl, aralkyl, or heteroaryl group; R2 is an optionally substituted aryl, aralkyl, or heteroaryl group; and R3 is a hydrogen atom or a C1-C6 alkyl group. A compound of the present invention has an excellent Weel kinase inhibiting effect, and is therefore useful in the filed of medicine, particularly in various types of cancer therapy.
摘要翻译： 本发明涉及以下通式（I）的化合物等。 在式中，Ar 1是任选取代的芳基或杂芳基; R 1是氢原子，任选取代的C 1 -C 6烷基或任选取代的芳基，芳烷基或杂芳基; R2是任选取代的芳基，芳烷基或杂芳基; 并且R 3是氢原子或C 1 -C 6烷基。 本发明的化合物具有优异的韦尔激酶抑制作用，因此可用于医药领域，特别是在各种类型的癌症治疗中。
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