公开(公告)号：US07584752B2

公开(公告)日：2009-09-08

申请号：US11277270

申请日：2006-03-23

申请人： Yvo Gärber ,  Hans Matthiessen ,  Dieter Weismann ,  Eckhard Teschner

发明人： Yvo Gärber ,  Hans Matthiessen ,  Dieter Weismann ,  Eckhard Teschner

IPC分类号： A61M15/00

CPC分类号： A61B5/0809 ,  A61B5/0536 ,  A61M16/024 ,  A61M2230/65

摘要： A device and a process for determining the change in the functional residual capacity (FRC) in a simple manner. Based on a first respiration phase for mechanical respiration, a recruitment maneuver is performed for this during a second respiration phase, and respiration is switched back to mechanical respiration during a third respiration phase. Reference values Uref/1, Uref/3 are formed from the end-expiratory values of the impedance measured signals U during the first respiration phase and the third respiration phase, and the difference ΔU (ΔFRC) between the reference value Uref/3 of the third respiration phase and the reference value Uref/1 of the first respiration phase is an indicator of the change in the functional residual capacity of the lung of the test subject.

摘要翻译： 用于以简单的方式确定功能剩余容量（FRC）的变化的装置和过程。 基于用于机械呼吸的第一呼吸阶段，在第二次呼吸阶段期间进行招募操作，并且在第三次呼吸阶段期间呼吸转换回机械呼吸。 参考值Uref / 1，Uref / 3由第一呼吸阶段和第三呼吸阶段期间的阻抗测量信号U的终点呼气值形成，以及在第一呼吸阶段和第三呼吸期间的参考值Uref / 3之间的差值DeltaU（DeltaFRC） 第三呼吸期和第一呼吸期的参考值Uref / 1是测试对象的肺功能残余容量变化的指标。

公开(公告)号：US07941210B2

公开(公告)日：2011-05-10

申请号：US11427516

申请日：2006-06-29

申请人： Hans Matthiessen ,  Dieter Weismann ,  Jianhua Li ,  Yvo Gärber ,  Arndt Pöcher ,  Markus Steeger

发明人： Hans Matthiessen ,  Dieter Weismann ,  Jianhua Li ,  Yvo Gärber ,  Arndt Pöcher ,  Markus Steeger

IPC分类号： A61B5/05 ,  G01R27/00 ,  G01R27/08

CPC分类号： A61B5/0536 ,  A61B5/0809 ,  H03F3/45475 ,  H03F3/45928 ,  H03F2200/261 ,  H03F2203/45138

摘要： An electroimpedance tomograph with a plurality of electrodes (1) is provided, which can be placed on the body of a patient and are connected via a selector switch (60) with a control and evaluating unit (20). The control and evaluating unit (20) cooperates with the selector switch (60) such that two electrodes each are supplied with an alternating current from an AC power source (22) and the detected analog voltage signals of the other electrodes are processed in order to reconstruct therefrom the impedance distribution of the body in the plane of the electrodes, wherein a symmetrical AC power source is used to reduce common-mode signals. To further suppress interferences due to common-mode signals, provisions are made for the control and evaluating unit (20) to be set up, furthermore, for detuning the common-mode signal of the alternating current on the body against the ground by means of a common-mode signal measuring electrode (4) and, based on this, the symmetry of the symmetrical AC power source such that the common-mode signal on the body is minimized, and the corresponding detuning parameters are stored for each electrode pair.

摘要翻译： 提供具有多个电极（1）的电阻抗断层摄影机，其可以放置在患者体上，并经由选择器开关（60）与控制和评估单元（20）连接。 控制和评估单元（20）与选择器开关（60）配合使得两个电极各自被提供有来自AC电源（22）的交流电，并且处理其它电极的检测到的模拟电压信号，以便 从而重建在电极的平面中的主体的阻抗分布，其中使用对称的AC电源来减少共模信号。 为了进一步抑制由于共模信号引起的干扰，为控制和评估单元（20）进行设置，此外，为了使身体上的交流电的共模信号与地面相互抵消，借助于 共模信号测量电极（4），并且基于此，对称AC电源的对称性使得主体上的共模信号最小化，并且针对每个电极对存储相应的失谐参数。

公开(公告)号：US07288943B2

公开(公告)日：2007-10-30

申请号：US11419318

申请日：2006-05-19

申请人： Hans Matthiessen ,  Dieter Weismann ,  Jianhua Li ,  Yvo Gärber

发明人： Hans Matthiessen ,  Dieter Weismann ,  Jianhua Li ,  Yvo Gärber

IPC分类号： G01R27/04 ,  G01R27/08 ,  A61B5/04 ,  A61B5/05

CPC分类号： A61B5/0536

摘要： An electroimpedance tomograph is provided with a plurality of electrodes (1), which can be placed on the body of a patient and are connected to a control and evaluating unit (20) via a selector switch (60). The control and evaluating unit (20) cooperates with the selector switch (60) such that two electrodes each are supplied with alternating current from an AC power source (22). The detected analog voltage signals of the other electrodes are sent into the control and evaluating unit (20) via a measuring amplifier (62) and AD converter (64) and are processed there in order to reconstruct the impedance distribution of the body in the plane of the electrodes therefrom. A symmetrical AC power source (22) is used to reduce common-mode signals. To make it possible to suppress errors due to common-mode signals, provisions are made for the control and evaluating unit (20) to be set up for making available an additional common-mode signal at an output during an adjusting mode of operation and to send it to the body via common-mode signal electrodes (4, 90) that can be placed on the body. The control and evaluating unit (20) is prepared, furthermore, to adjust the measuring amplifier (62) according to value and phase for each electrode pair connected by the selector switch (60) such that the common-mode signal at the output of the measuring amplifier (62) is minimized, and the adjusted parameters are stored for each electrode pair.

摘要翻译： 电阻断层摄影机设置有多个电极（1），其可以放置在患者的身体上，并且经由选择器开关（60）连接到控制和评估单元（20）。 控制和评估单元（20）与选择器开关（60）配合，使得两个电极各自由AC电源（22）提供交流电。 检测出的其他电极的模拟电压信号通过测量放大器（62）和AD转换器（64）发送到控制和评估单元（20），并在那里进行处理，以便重建在平面内的主体的阻抗分布 的电极。 使用对称的交流电源（22）来减少共模信号。 为了能够抑制由于共模信号引起的误差，为了使控制和评估单元（20）被设置成在调节操作模式期间在输出端提供额外的共模信号，并且 通过可以放置在身体上的共模信号电极（4,90）将其发送到身体。 此外，准备控制和评估单元（20）根据由选择器开关（60）连接的每个电极对的值和相位来调节测量放大器（62），使得在输出端的共模信号 测量放大器（62）被最小化，并且为每个电极对存储调整的参数。

公开(公告)号：US08105242B2

公开(公告)日：2012-01-31

申请号：US11675872

申请日：2007-02-16

申请人： Eckhard Teschner ,  Dieter Weismann

发明人： Eckhard Teschner ,  Dieter Weismann

IPC分类号： A61B5/08

CPC分类号： A61B5/0536 ,  A61M16/022 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2230/65 ,  A61M2230/005

摘要： A process with a corresponding device for lung ventilation involves recording an image of the lung status with an electric impedance tomography (EIT) system (2) and the total area of ventilated lung areas is determined by a computing unit (4) from all image values, subsequently divided into at least two lung areas and the extent of the homogeneity of the ventilated lung areas is determined by comparison of the impedance changes within these areas. In case of a homogeneity rated as being too low, the respiration pressures are increased step by step by means of the respirator (1) and the respiration pressure at which the greatest possible homogeneity is obtained from subsequently determined status images is determined by means of the EIT system (2). The respiration pressure is subsequently lowered again by the respirator (1) until the computing unit (4) detects a reduction in the homogeneity of ventilated lung areas, so that the respiration pressure is subsequently increased again by means of the respirator (1) to the last value at which no reduction in the homogeneity of the ventilated lung areas occurred.

摘要翻译： 具有用于肺通气的相应装置的过程包括用电阻抗断层摄影（EIT）系统（2）记录肺状态的图像，并且通过计算单元（4）从所有图像值确定通气肺区域的总面积 ，随后分为至少两个肺部区域，通过比较这些区域内的阻抗变化来确定通气肺区域的均匀程度。 在均匀性被评定为太低的情况下，呼吸压力通过呼吸器（1）逐步增加，并且从后续确定的状态图像获得最大可能的均匀性的呼吸压力通过 EIT系统（2）。 呼吸压力随后由呼吸器（1）再次降低，直到计算单元（4）检测到通气肺区域的均匀性降低，使得呼吸压力随后通过呼吸器（1）再次增加到 发生通气肺部不均匀的最后一个值。

公开(公告)号：US07896814B2

公开(公告)日：2011-03-01

申请号：US11675800

申请日：2007-02-16

申请人： Eckhard Teschner ,  Dieter Weismann

发明人： Eckhard Teschner ,  Dieter Weismann

IPC分类号： A61B5/085

CPC分类号： A61B5/0536 ,  A61M16/022 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2230/65 ,  A61M2230/005

摘要： An electro-impedance tomography (EIT) system (2), with a computing unit (4) and a respirator (1) is described for gentle mechanical lung ventilation especially in case of atelectases. The presence, the extent and/or the spatial distribution of atelectases is detected by the EIT system (2) and sent to the respirator (1) so that the respiration pressure is increased step by step by the respirator (1) until the current image of the lung status corresponds to a first status image of healthy lungs or comes close to it with minimal deviations. The respiration pressure is subsequently reduced again step by step by the respirator (1) until the computing unit (4) detects a reduction of the ventilated lung areas and the respiration pressure is subsequently increased again by means of the respirator (1) to the last value at which no change occurred in the ventilated lung areas.

摘要翻译： 描述了具有计算单元（4）和呼吸器（1）的电阻抗层析成像（EIT）系统（2），用于轻度机械肺通气，特别是在选择的情况下。 选择酶的存在，程度和/或空间分布由EIT系统（2）检测并发送到呼吸器（1），使得呼吸压力由呼吸器（1）逐步增加，直到当前图像 的肺状态对应于健康肺的第一状态图像或以最小的偏差接近它。 呼吸压力随后由呼吸器（1）逐步减少，直到计算单元（4）检测到通气的肺部区域的减少，并且呼吸压力随后通过呼吸器（1）再次增加到最后 通气肺部无变化的值。

公开(公告)号：US08627820B2

公开(公告)日：2014-01-14

申请号：US11754541

申请日：2007-05-29

申请人： Hans Matthiessen ,  Dieter Weismann ,  Marcus Eger

发明人： Hans Matthiessen ,  Dieter Weismann ,  Marcus Eger

IPC分类号： F16K31/02

CPC分类号： A61M16/203 ,  A61B5/085 ,  A61B5/087 ,  A61M16/0069 ,  A61M16/026 ,  A61M16/06 ,  A61M2016/0027 ,  A61M2016/0033

摘要： A device for supplying a patient with breathing gas, in which an initially high initial pressure Paw(t=0) applied from the outside is automatically lowered by means of a control circuit to a lower inspiratory pressure Paw(t) as soon as a pulmonary internal pressure Plung(t) threatens to exceed a predetermined pulmonary target pressure Plung,soll. Overinflation of the lungs due to the respiration is thus ruled out according to the present invention. The device permits, moreover, rapid filling of the lungs with breathing gas and makes thus possible a comparatively long phase of expiration. A process is also provided for regulating a respirator and for respirating a patient.

摘要翻译： 用于向患者提供呼吸气体的装置，其中从外部施加的初始高初始压力Paw（t = 0）一旦肺部被吸入，通过控制电路自动降低到较低的吸气压力Paw（t） 内部压力Plung（t）威胁超过预定的肺部目标压力Plung，soll。 因此根据本发明排除了由呼吸引起的肺的过度充气。 此外，该装置还允许用呼吸气体快速填充肺，并且因此可能达到相对较长的呼气阶段。 还提供了一种用于调节呼吸器和呼吸患者的过程。

公开(公告)号：US20080000478A1

公开(公告)日：2008-01-03

申请号：US11754541

申请日：2007-05-29

申请人： Hans Matthiessen ,  Dieter Weismann ,  Marcus Eger

发明人： Hans Matthiessen ,  Dieter Weismann ,  Marcus Eger

IPC分类号： A61M16/00

CPC分类号： A61M16/203 ,  A61B5/085 ,  A61B5/087 ,  A61M16/0069 ,  A61M16/026 ,  A61M16/06 ,  A61M2016/0027 ,  A61M2016/0033

摘要： A device for supplying a patient with breathing gas, in which an initially high initial pressure paw(t=0) applied from the outside is automatically lowered by means of a control circuit to a lower inspiratory pressure paw(t) as soon as a pulmonary internal pressure plung(t) threatens to exceed a predetermined pulmonary target pressure plung,soll. Overinflation of the lungs due to the respiration is thus ruled out according to the present invention. The device permits, moreover, rapid filling of the lungs with breathing gas and makes thus possible a comparatively long phase of expiration. A process is also provided for regulating a respirator and for respirating a patient.

摘要翻译： 用于向患者提供呼吸气体的装置，其中从外部施加的初始高初始压力p（aw = 0）通过控制电路自动降低到较低的吸气压力p 一旦肺内压肺（t）威胁超过预定的肺部目标压力肺，就可以使肺（t） 。 因此根据本发明排除了由呼吸引起的肺的过度充气。 此外，该装置还允许用呼吸气体快速填充肺，并且因此可能达到相对较长的呼气阶段。 还提供了一种用于调节呼吸器和呼吸患者的过程。

公开(公告)号：US08397720B2

公开(公告)日：2013-03-19

申请号：US12112485

申请日：2008-04-30

申请人： Marcus Eger ,  Dieter Weismann

发明人： Marcus Eger ,  Dieter Weismann

IPC分类号： F16K31/02 ,  A61M16/00

CPC分类号： A61M16/026 ,  A61M2016/0027

摘要： Operating a respirator with an inspiration pressure-vs.-time curve (1), which has an airway target pressure (paw—target) and a PEEP (3), in which the inspiration pressure-vs.-time curve (1) reaches the airway target pressure (paw—target) on a ramp-like curve (17) starting from a starting airway pressure (paw—Start), which is greater than the PEEP (3).

摘要翻译： 操作具有吸气压力 - 时间曲线（1）的呼吸器，其具有气道目标压力（爪 - 目标）和PEEP（3），其中吸气压力 - 时间曲线（1）达到 从起始气道压力（爪启动）开始的斜坡状曲线（17）上的气道目标压力（爪 - 目标）大于PEEP（3）。

公开(公告)号：US07882835B2

公开(公告)日：2011-02-08

申请号：US11554905

申请日：2006-10-31

申请人： Marcus Eger ,  Dieter Weismann

发明人： Marcus Eger ,  Dieter Weismann

IPC分类号： A62B7/04 ,  F16K31/26

CPC分类号： A61M16/205 ,  A61M16/026 ,  A61M16/204 ,  A61M2016/0027 ,  A61M2016/0036 ,  A61M2205/15

摘要： A method, system and device are provided for the determination of leaks in a respirator. An inspiraton pressure pinsp is recorded during an inspiration time Tinsp with a measuring device. The inspiration pressure pinsp is varied during consecutive breaths I. Leaks are determined as to leak volumes VLi from the product of pinspi and Tinspi in accordance with the equation VLi=A×pinspiB×Tinspi while the parameters A and B are determined in an analyzing unit by a regression model with pinsp as the regressor.

摘要翻译： 提供了一种用于确定呼吸器泄漏的方法，系统和装置。 在吸气时间Tinsp与测量装置记录灵感压力针脚。 吸气压力针脚在连续呼吸时变化I.泄漏确定为根据等式VLi = A×pinspiB×Tinspi从销钉和Tinspi的产品泄漏体积VLi，而参数A和B在分析单元中确定 通过一个回归模型与pinp作为回归。

公开(公告)号：US5303700A

公开(公告)日：1994-04-19

申请号：US908972

申请日：1992-07-06

申请人： Dieter Weismann ,  Marcel Baum

发明人： Dieter Weismann ,  Marcel Baum

IPC分类号： A61M16/00

CPC分类号： A61M16/00 ,  A61M2016/0021 ,  A61M2016/0036

摘要： The invention relates to a method for recognizing the respiratory phases of a patient for controlling a ventilating apparatus. The time-dependent trace of a signal, which represents the respiratory flow curve and is emitted by a signal device, is determined and from this trace, a trigger criterium is obtained for the switchover of the ventilating apparatus from the expiration phase into the inspiration phase and/or from the inspiration phase into the expiration phase. The method is improved in that even for chronically obstructive patients, a reliable and early recognition of the inspiration and expiration attempts is possible. A significant increase of the slope of the respiratory flow curve between each two zero crossovers of this curve is used as a trigger criterium.

摘要翻译： 本发明涉及一种识别患者呼吸相位的方法，用于控制通气装置。 确定表示呼吸流量曲线并由信号装置发出的信号的时间依赖性迹线，并且从该迹线获得用于从通气装置从呼气阶段切换到吸气阶段的触发标准 和/或从启发阶段进入到期阶段。 该方法得到改进，即使对于慢性阻塞性患者来说，可以早日识别灵感和呼气试验。 作为触发标准，使用该曲线的每两个零交叉点之间的呼吸流量曲线的斜率的显着增加。