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公开(公告)号：US10914934B2
公开(公告)日：2021-02-09
申请号：US16080287
申请日：2018-01-25
Applicant: ZHEJIANG UNIVERSITY
Inventor： Zhenrong Zheng , Xiao Tao , Wentao Zhang , Chenning Tao , Haifeng Li , Xu Liu
Abstract: The invention discloses a wide-field multi-scale high-resolution microscopic imaging system, which includes a light source, a sample, a microscope imaging objective system, an acquisition system, and a workstation. The microscope imaging objective system is used for forming an image after a light beam emitted by the light source illuminates the sample. To obtain a wide-field curved image plane, the acquisition system includes an acquisition lens array for subfield acquisition of the curved image plane, and a camera array for secondary imaging. The workstation is used for analyzing the acquired image in overlapping fields of view, and performing image splicing based on the fields of view, to finally obtain a wide-field high-resolution image. Because of the desire for an improvement to an imaging method, this invention realizes multi-scale high-resolution observation from cells, tissues, to organs while ensuring a wide field of view.
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2.发明授权公开(公告)号：US10754127B2
公开(公告)日：2020-08-25
申请号：US16091954
申请日：2018-01-25
Applicant: ZHEJIANG UNIVERSITY
Inventor： Zhenrong Zheng , Xiao Tao , Wentao Zhang , Chenning Tao , Haifeng Li , Xu Liu
Abstract: The present invention discloses a micro-objective lens, comprising the first lens group, the second lens group, the third lens group, the fourth lens group, the fifth lens group, the sixth lens group, the seventh lens group, the eighth lens group, the ninth lens group and the tenth lens group with optical axis arranged in a sequence from the left to the right; the focal length of the first lens group is negative; the second lens group belongs to doublet, in which the focal length of the first and second lens is positive and negative respectively; the focal length of the third lens group is positive; the fourth and fifth lens groups belongs to doublets, in which the focal length of the first and second lens in each group is negative and positive respectively; the focal length of the sixth lens group is positive; the focal length of the seventh and eighth lens groups is negative; the focal length of the ninth and tenth lens groups is positive. The present invention also discloses a high-resolution broadband imaging system with aforesaid micro-objective lens.
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Patent Agency Ranking
公开(公告)号：US09625627B2
公开(公告)日：2017-04-18
申请号：US14412361
申请日：2014-01-02
Applicant: ZHEJIANG UNIVERSITY
Inventor： Weidong Shen , Chenying Yang , Yueguang Zhang , Xu Liu
CPC classification number: G02B5/207 , G02B1/02 , G02B5/1819 , G02B5/201
Abstract: The belt ply feeder and a feeding method include: when a belt ply is conveyed to the front end of a conveying forming board, a force is exerted by a perpendicular adjustment device to drive a conveying forming board bracket to swing upward and rotate around a pivot shaft of a rack to positions at which the upper surface of the conveying forming board is tangential to the periphery of a belt ply drum. According to this arrangement, the belt ply is tangential to the belt ply drum all the time and a belt ply is in firm contact with a belt ply drum regardless of the size of the belt ply drum when wrapping the belt ply around the belt ply drum. Accordingly, the quality of tire shaping can be improved.
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公开(公告)号：US20150211986A1
公开(公告)日：2015-07-30
申请号：US14411373
申请日：2012-10-22
Applicant: ZHEJIANG UNIVERSITY
Inventor： Cuifang Kuang , Shuai Li , Xiang Hao , Zhaotai Gu , Xu Liu
CPC classification number: G01N21/27 , G01N21/255 , G01N21/6458 , G01N2201/06113 , G01N2201/064 , G02B21/002 , G02B21/0032 , G02B21/0068 , G02B27/58
Abstract: This invention discloses a super-resolution microscopy method and device, of which the method comprises the following steps: converting laser beam into linearly polarized light after collimation; linearly polarized light is deflected and phase modulated by a spatial light modulator; the deflected beam is focused, collimated and then converted into circularly polarized light for projection on the sample to collect signal light from various scanning points on the sample, and obtaining the first signal light intensity; switching over modulation function to project linearly polarized light modulated by the second phase modulation on the sample to collect signal light from various scanning points on the sample, and obtaining the second signal light intensity; calculating valid signal light intensity to obtain the super-resolution image. This device features in a simple structure and easy operation, which can obtain a super-resolution beyond diffraction limit at a lower luminous power; it is quick in image formation with the frame frequency over 15 frames when the number of scanning points in each image is 512×512 .
Abstract translation: 本发明公开了一种超分辨率显微镜方法和装置，其方法包括以下步骤：准直后将激光束转换成线偏振光; 线性偏振光被空间光调制器偏转和相位调制; 偏转光束被聚焦，准直，然后转换成圆偏振光，用于投射在样品上，以从样品上的各个扫描点收集信号光，并获得第一信号光强度; 切换调制功能，将样品上的第二相位调制调制的线偏振光投射到样品上的各个扫描点，以获得第二信号光强度; 计算有效信号光强度以获得超分辨率图像。 该器件结构简单，操作方便，可以在较低的发光功率下获得超过衍射极限的超分辨率; 当每个图像中的扫描点数量为512×512时，帧频超过15帧的图像形成速度很快。
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公开(公告)号：US09568417B2
公开(公告)日：2017-02-14
申请号：US14411373
申请日：2012-10-22
Applicant: ZHEJIANG UNIVERSITY
Inventor： Cuifang Kuang , Shuai Li , Xiang Hao , Zhaotai Gu , Xu Liu
CPC classification number: G01N21/27 , G01N21/255 , G01N21/6458 , G01N2201/06113 , G01N2201/064 , G02B21/002 , G02B21/0032 , G02B21/0068 , G02B27/58
Abstract: This invention discloses a super-resolution microscopy method and device, of which the method comprises the following steps: converting laser beam into linearly polarized light after collimation; linearly polarized light is deflected and phase modulated by a spatial light modulator; the deflected beam is focused, collimated and then converted into circularly polarized light for projection on the sample to collect signal light from various scanning points on the sample, and obtaining the first signal light intensity; switching over modulation function to project linearly polarized light modulated by the second phase modulation on the sample to collect signal light from various scanning points on the sample, and obtaining the second signal light intensity; calculating valid signal light intensity to obtain the super-resolution image. This device features in a simple structure and easy operation, which can obtain a super-resolution beyond diffraction limit at a lower luminous power; it is quick in image formation with the frame frequency over 15 frames when the number of scanning points in each image is 512×512.
Abstract translation: 本发明公开了一种超分辨率显微镜方法和装置，其方法包括以下步骤：准直后将激光束转换成线偏振光; 线性偏振光被空间光调制器偏转和相位调制; 偏转光束被聚焦，准直，然后转换成圆偏振光，用于投射在样品上，以从样品上的各个扫描点收集信号光，并获得第一信号光强度; 切换调制功能，将样品上的第二相位调制调制的线偏振光投射到样品上的各个扫描点的信号光，并获得第二信号光强度; 计算有效信号光强度以获得超分辨率图像。 该器件结构简单，操作方便，可以在较低的发光功率下获得超过衍射极限的超分辨率; 当每个图像中的扫描点数量为512×512时，帧频超过15帧的图像形成速度很快。
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公开(公告)号：US12130554B2
公开(公告)日：2024-10-29
申请号：US18404934
申请日：2024-01-05
Applicant: ZHEJIANG LAB , ZHEJIANG UNIVERSITY
Inventor： Cuifang Kuang , Hongqing Wang , Ziang Wang , Zhenyao Yang , Mengbo Tang , Lanxin Zhan , Xiaoyi Zhang , Jisen Wen , Xu Liu
CPC classification number: G03F7/2053 , G03F7/70391 , G03F7/704
Abstract: A method and an apparatus for direct writing photoetching by parallel interpenetrating super-resolution high-speed laser. The method of the present application uses a parallel interpenetrating algorithm. Firstly, a multi-beam solid light spot for writing is generated based on a writing light spatial light modulator; a multi-beam hollow light spot for inhibition is generated based on an inhibition optical spatial light modulator; the multi-beam solid light spot is combined with the multi-beam hollow light spot to generate a modulated multi-beam light spot; a writing waveform is output based on a multichannel acousto-optic modulator, a displacement stage moves at a constant speed until writing of a whole column of areas is completed, an optical switch is turned off, and the displacement stage conducts one-time stepping movement; the process is not stopped until all patterns are written.
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公开(公告)号：US10481305B2
公开(公告)日：2019-11-19
申请号：US15329569
申请日：2015-09-21
Applicant: ZHEJIANG UNIVERSITY
Inventor： Weidong Shen , Chenying Yang , Yueguang Zhang , Bo Fang , Xu Liu
Abstract: The present invention discloses a visible near-infrared ultra-broadband absorber and its preparation method, comprising a substrate and a five-layer optical film, wherein the bottom film is a bottom metal absorbing layer; a top germanium layer is provided on the top of the bottom metal absorbing layer; and remaining three layers are provided on the top of the top germanium layer with gradually decreasing refractive indexes from the bottom to the top. The present invention is based on the blocking effect of the metal absorbing layer and broadband anti-reflection film stack of the germanium layer, which has realized visible near-infrared ultra-broadband absorption with high efficiency and good angle insensitivity, and has fully surpassed traditional absorbers in terms of performances. Compared with conventional broadband absorbers and artificial electromagnetic absorbers proposed in recent years, the compact multilayer film structure in the present invention is simpler and avoids complicated nano-fabrication techniques. Therefore, it can significantly reduce production cost and shorten the production cycle, and is thus suitable for large-scale mass production.
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