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公开(公告)号：US07053193B2
公开(公告)日：2006-05-30
申请号：US10054935
申请日：2002-01-25
申请人： Zairen Sun , Wufang Fan , Karl F. Kovacs , Xuan Li , Gilbert Jay
发明人： Zairen Sun , Wufang Fan , Karl F. Kovacs , Xuan Li , Gilbert Jay
IPC分类号： C07H21/04
CPC分类号： G01N33/57415 , A01K2217/05 , A61K38/00 , C07K14/4702 , C12Q1/6886
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides, Urb-ctf, are expressed in breast cancer and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions especially related to breast cancer.
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公开(公告)号：US20050069886A1
公开(公告)日：2005-03-31
申请号：US10494940
申请日：2002-11-07
申请人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Wufang Fan
发明人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Wufang Fan
CPC分类号： C12Q1/6886 , C12Q2600/136 , C12Q2600/158
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are differentially-regulated in prostate cancer and are therefore useful in variety of ways. including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions, to prostate cancer.
摘要翻译： 本发明涉及新型多核苷酸的所有方面，它们编码的多肽，抗体及其特异性结合伴侣，以及它们在研究，诊断，药物发现，治疗，临床医学，法医学和医学等中的应用。多核苷酸是差异化的 在前列腺癌中有调节作用，因此在各种方面都是有用的。 包括但不限于作为药物靶标的分子标记，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定前列腺癌的疾病和病症等等。
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公开(公告)号：US06780595B2
公开(公告)日：2004-08-24
申请号：US10082272
申请日：2002-02-26
申请人： Youmin Shu , Wufang Fan , Karl F. Kovacs , Xuan Li , Gilbert Jay
发明人： Youmin Shu , Wufang Fan , Karl F. Kovacs , Xuan Li , Gilbert Jay
IPC分类号： C12Q168
CPC分类号： C12Q1/6883 , A61K38/00 , C07K14/47 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G06Q30/0601
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are expressed in heart and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions of the heart and eye.
摘要翻译： 本发明涉及新型多核苷酸，它们编码的多肽，抗体及其特异性结合伴侣的所有方面及其在研究，诊断，药物发现，治疗，临床医学，法医学和医学等方面的应用。多核苷酸被表达 因此在各种方式中有用，包括但不限于作为分子标志物，作为药物靶标，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定疾病的易感性等 和心脏和眼睛的条件。
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公开(公告)号：US20060241015A1
公开(公告)日：2006-10-26
申请号：US10502394
申请日：2003-01-24
申请人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Wufang Fan , Youmin Shu
发明人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Wufang Fan , Youmin Shu
CPC分类号： G01N33/574 , A61K38/00 , C07K14/4748 , C12Q1/6886 , C12Q2600/136 , G06Q50/22 , Y02A90/22 , Y02A90/26
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are differentially expressed in prostate and breast cancers and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., cancers.
摘要翻译： 本发明涉及新型多核苷酸的所有方面，它们编码的多肽，抗体及其特异性结合伴侣，以及它们在研究，诊断，药物发现，治疗，临床医学，法医学和医学等中的应用。多核苷酸是差异化的 在前列腺癌和乳腺癌中表达，因此可用于多种方式，包括但不限于作为分子标志物，作为药物靶标，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定易感性， 等等，癌症。
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公开(公告)号：US20050120393A1
公开(公告)日：2005-06-02
申请号：US10485555
申请日：2002-08-02
申请人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Youmin Shu , Wufang Fan
发明人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Youmin Shu , Wufang Fan
IPC分类号： A01K67/00 , C07H21/04 , C07K14/47 , C07K14/705 , C12Q1/68 , G01N33/50 , G01N33/574 , G06F17/60
CPC分类号： C07K14/47 , A01K2267/0331 , C07K14/4702 , C07K14/705 , C12Q1/6886 , C12Q2600/136 , C12Q2600/156 , G01N33/5091 , G01N33/57434 , G01N2500/10 , G01N2800/342
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science, pathology, and medicine, etc. The polynucleotides are expressed in prostate and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions relating to prostate, such as prostate cancers, as well as other disease and conditions.
摘要翻译： 本发明涉及新型多核苷酸，它们编码的多肽，抗体及其特异性结合伴侣的所有方面及其在研究，诊断，药物发现，治疗，临床医学，法医学，病理学和医学等方面的应用。 多核苷酸在前列腺中表达，因此可用于多种方式，包括但不限于作为分子标志物，作为药物靶标，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定等等的倾向 ，与前列腺相关的疾病和病症，如前列腺癌，以及其他疾病和病症。
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公开(公告)号：US20050055733A1
公开(公告)日：2005-03-10
申请号：US10482838
申请日：2002-07-08
申请人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Youmin Shu , Wufang Fan
发明人： Zairen Sun , Xuan Li , Gilbert Jay , Karl Kovacs , Youmin Shu , Wufang Fan
IPC分类号： C07K14/47 , C12Q1/68 , A01K67/00 , C07K14/705
CPC分类号： C07K14/47
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science, pathology, and medicine, etc. The polynucleotides are expressed in small intestine or colon and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions relating to small intestine or colon.
摘要翻译： 本发明涉及新型多核苷酸，它们编码的多肽，抗体及其特异性结合伴侣的所有方面及其在研究，诊断，药物发现，治疗，临床医学，法医学，病理学和医学等方面的应用。 多核苷酸在小肠或结肠中表达，因此可以多种方式使用，包括但不限于作为分子标志物，作为药物靶标，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定易感性 等等，与小肠或结肠相关的疾病和病症。
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公开(公告)号：US20050019818A1
公开(公告)日：2005-01-27
申请号：US10921807
申请日：2004-08-20
申请人： Youmin Shu , Wufang Fan , Karl Kovacs , Xuan Li , Gilbert Jay
发明人： Youmin Shu , Wufang Fan , Karl Kovacs , Xuan Li , Gilbert Jay
CPC分类号： C12Q1/6883 , A61K38/00 , C07K14/47 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G06Q30/0601
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are expressed in heart and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions of the heart and eye.
摘要翻译： 本发明涉及新型多核苷酸，它们编码的多肽，抗体及其特异性结合伴侣的所有方面及其在研究，诊断，药物发现，治疗，临床医学，法医学和医学等方面的应用。多核苷酸被表达 因此在各种方式中有用，包括但不限于作为分子标志物，作为药物靶标，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定疾病的易感性等 和心脏和眼睛的条件。
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公开(公告)号：US06657054B1
公开(公告)日：2003-12-02
申请号：US10164595
申请日：2002-06-10
申请人： Zairen Sun , Xuan Li , Gilbert Jay
发明人： Zairen Sun , Xuan Li , Gilbert Jay
IPC分类号： C07H2104
CPC分类号： C07K14/47 , C07K14/515
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are modulated during angiogeneis and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions, determining predisposition to, etc., diseases and conditions, such as abnormal, insufficient, excessive, etc., angiogenesis, inflammatory diseases, rheumatoid arthritis, osteoarthritis, asthma, pulmonary fibrosis, age-related macular degeneration (ARMD), diabetic retinopathy, macular degeneration, and retinopathy of prematurity (ROP), endometriosis, cancer, Coats' disease, peripheral retinal neovascularization, neovascular glaucoma, psoriasis, retrolental fibroplasias, angiofibroma, inflammation, etc.
摘要翻译： 本发明涉及新型多核苷酸的所有方面，它们编码的多肽，抗体及其特异性结合伴侣，以及它们在研究，诊断，药物发现，治疗，临床医学，法医学和医学等中的应用。多核苷酸被调节 在血管新生期间，因此可以多种方式使用，包括但不限于作为分子标志物，作为药物靶标，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定疾病等等的倾向 血管生成，炎症性疾病，类风湿性关节炎，骨关节炎，哮喘，肺纤维化，年龄相关性黄斑变性（ARMD），糖尿病等疾病和病症的易感性 视网膜病变，黄斑变性和早产儿视网膜病变（ROP），子宫内膜异位症，癌症，大衣病，外周视网膜新生血 鳞状，新生血管性青光眼，牛皮癣，复发性纤维瘤，血管纤维瘤，炎症等
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公开(公告)号：US20050106579A1
公开(公告)日：2005-05-19
申请号：US10717665
申请日：2003-11-21
申请人： Zairen Sun , Xuan Li , Gilbert Jay
发明人： Zairen Sun , Xuan Li , Gilbert Jay
IPC分类号： C07K14/47 , C07K14/515 , C12Q1/68 , C07H21/04 , C07K14/475 , C12N9/64
CPC分类号： C07K14/47 , C07K14/515
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are modulated during angiogeneis and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions, determining predisposition to, etc., diseases and conditions, such as abnormal, insufficient, excessive, etc., angiogenesis, inflammatory diseases, rheumatoid arthritis, osteoarthritis, asthma, pulmonary fibrosis, age-related macular degeneration (ARMD), diabetic retinopathy, macular degeneration, and retinopathy of prematurity (ROP), endometriosis, cancer, Coats' disease, peripheral retinal neovascularization, neovascular glaucoma, psoriasis, retrolental fibroplasias, angiofibroma, inflammation, etc.
摘要翻译： 本发明涉及新型多核苷酸的所有方面，它们编码的多肽，抗体及其特异性结合伴侣，以及它们在研究，诊断，药物发现，治疗，临床医学，法医学和医学等中的应用。多核苷酸被调节 在血管新生期间，因此可以多种方式使用，包括但不限于作为分子标志物，作为药物靶标，以及用于检测，诊断，分期，监测，预后，预防或治疗，确定疾病等等的倾向 血管生成，炎症性疾病，类风湿性关节炎，骨关节炎，哮喘，肺纤维化，年龄相关性黄斑变性（ARMD），糖尿病等疾病和病症的易感性 视网膜病变，黄斑变性和早产儿视网膜病变（ROP），子宫内膜异位症，癌症，大衣病，外周视网膜新生血 鳞状，新生血管性青光眼，牛皮癣，复发性纤维瘤，血管纤维瘤，炎症等
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公开(公告)号：US06833247B2
公开(公告)日：2004-12-21
申请号：US10144198
申请日：2002-05-14
申请人： Zairen Sun , Xuan Li , Gilbert Jay
发明人： Zairen Sun , Xuan Li , Gilbert Jay
IPC分类号： C12Q168
CPC分类号： C07K14/4748 , A61K38/00 , Y02A90/26
摘要： The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are differentially-regulated in prostate cancer and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions, to prostate cancer.
摘要翻译： 本发明涉及新型多核苷酸的所有方面，它们编码的多肽，抗体及其特异性结合伴侣，以及它们在研究，诊断，药物发现，治疗，临床医学，法医学和医学等中的应用。多核苷酸是差异化的 在前列腺癌中有调节作用，因此可以多种方式使用，包括但不限于分子标记物，药物靶标，检测，诊断，分期，监测，预后，预防或治疗，确定易感性等。 ，疾病和病症，前列腺癌。
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