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公开(公告)号：US10194986B2
公开(公告)日：2019-02-05
申请号：US15395966
申请日：2016-12-30
摘要： Disclosed herein are optical assemblies having thin, low profile shapes. These optical assemblies may be used with fiber coupled lasers and other light sources, including high power sources, to irradiate tissue at a wavelength suitable for inducing ablation or coagulation to a target depth, denaturation, thermal modification of a tissue, and/or preferential injury to a target tissue structure. Example optical assemblies can produce substantially uniform illumination patterns that are useful for treating superficial tissue, including the internal or luminal (e.g., esophageal) tissue. Some examples may have capability for cooling superficial tissue or skin, such as a detachable, reusable heat sink for active cooling without consumables, fluid pumps, or other cooling equipment.
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公开(公告)号：US20180325593A1
公开(公告)日：2018-11-15
申请号：US15970742
申请日：2018-05-03
发明人： Kathleen McMillan
CPC分类号： A61B18/20 , A61B5/01 , A61B18/201 , A61B18/203 , A61B18/22 , A61B18/24 , A61B2018/00023 , A61B2018/00452 , A61B2018/00476 , A61B2018/00791 , A61F9/008 , A61N5/0601 , A61N5/0616 , A61N5/062 , A61N2005/0652 , A61N2005/0659 , A61N2005/067
摘要： An apparatus for treatment of soft tissue includes a source of radiation, a handpiece which is adapted to transmit radiation emitted from the source of radiation to a region of soft tissue, resulting in irradiated soft tissue, said handpiece being positioned adjacent to or in contact with said soft tissue region, a grid element adapted to hold at least one temperature sensor in contact with or embedded in said region of soft tissue, and a microprocessor, which converts a signal from the at least one temperature sensor into a measure of damage produced in at least two components of the irradiated soft tissue, said components comprising at least one normal tissue component and at least one malignant, hypertrophic, diseased, or unwanted component.
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公开(公告)号：US20170304003A1
公开(公告)日：2017-10-26
申请号：US15395966
申请日：2016-12-30
IPC分类号： A61B18/22
CPC分类号： A61B18/22
摘要： Disclosed herein are optical assemblies having thin, low profile shapes. These optical assemblies may be used with fiber coupled lasers and other light sources, including high power sources, to irradiate tissue at a wavelength suitable for inducing ablation or coagulation to a target depth, denaturation, thermal modification of a tissue, and/or preferential injury to a target tissue structure. Example optical assemblies can produce substantially uniform illumination patterns that are useful for treating superficial tissue, including the internal or luminal (e.g., esophageal) tissue. Some examples may have capability for cooling superficial tissue or skin, such as a detachable, reusable heat sink for active cooling without consumables, fluid pumps, or other cooling equipment.
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公开(公告)号：US20130345687A1
公开(公告)日：2013-12-26
申请号：US13965715
申请日：2013-08-13
IPC分类号： A61B18/22
CPC分类号： A61B18/22
摘要： Disclosed herein are optical assemblies having thin, low profile shapes. These optical assemblies may be used with fiber coupled lasers and other light sources, including high power sources, to irradiate tissue at a wavelength suitable for inducing ablation or coagulation to a target depth, denaturation, thermal modification of a tissue, and/or preferential injury to a target tissue structure. Example optical assemblies can produce substantially uniform illumination patterns that are useful for treating superficial tissue, including the internal or luminal (e.g., esophageal) tissue. Some examples may have capability for cooling superficial tissue or skin, such as a detachable, reusable heat sink for active cooling without consumables, fluid pumps, or other cooling equipment.
摘要翻译： 本文公开了具有薄的，低轮廓形状的光学组件。 这些光学组件可以与光纤耦合激光器和其他光源（包括高功率源）一起使用，以适合于诱导消融或凝结到目标深度，变性，组织热修饰和/或优惠伤害的波长照射组织 到目标组织结构。 示例性光学组件可以产生用于治疗表面组织（包括内部或内腔（例如食道））组织的基本上均匀的照明图案。 一些示例可能具有冷却表面组织或皮肤的能力，例如可拆卸的可重复使用的散热器，用于主动冷却而不使用消耗品，流体泵或其它冷却设备。
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公开(公告)号：US11147623B2
公开(公告)日：2021-10-19
申请号：US15970742
申请日：2018-05-03
发明人： Kathleen McMillan
摘要： An apparatus for treatment of soft tissue includes a source of radiation, a handpiece which is adapted to transmit radiation emitted from the source of radiation to a region of soft tissue, resulting in irradiated soft tissue, said handpiece being positioned adjacent to or in contact with said soft tissue region, a grid element adapted to hold at least one temperature sensor in contact with or embedded in said region of soft tissue, and a microprocessor, which converts a signal from the at least one temperature sensor into a measure of damage produced in at least two components of the irradiated soft tissue, said components comprising at least one normal tissue component and at least one malignant, hypertrophic, diseased, or unwanted component.
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公开(公告)号：US09554856B2
公开(公告)日：2017-01-31
申请号：US13965715
申请日：2013-08-13
CPC分类号： A61B18/22
摘要： Disclosed herein are optical assemblies having thin, low profile shapes. These optical assemblies may be used with fiber coupled lasers and other light sources, including high power sources, to irradiate tissue at a wavelength suitable for inducing ablation or coagulation to a target depth, denaturation, thermal modification of a tissue, and/or preferential injury to a target tissue structure. Example optical assemblies can produce substantially uniform illumination patterns that are useful for treating superficial tissue, including the internal or luminal (e.g., esophageal) tissue. Some examples may have capability for cooling superficial tissue or skin, such as a detachable, reusable heat sink for active cooling without consumables, fluid pumps, or other cooling equipment.
摘要翻译： 本文公开了具有薄的，低轮廓形状的光学组件。 这些光学组件可以与光纤耦合激光器和其他光源（包括高功率源）一起使用，以适合于诱导消融或凝结到目标深度，变性，组织热修饰和/或优惠伤害的波长照射组织 到目标组织结构。 示例性光学组件可以产生用于治疗表面组织（包括内部或内腔（例如食道））组织的基本上均匀的照明图案。 一些示例可能具有冷却表面组织或皮肤的能力，例如可拆卸的可重复使用的散热器，用于主动冷却而不使用消耗品，流体泵或其它冷却设备。
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公开(公告)号：US20140194770A1
公开(公告)日：2014-07-10
申请号：US14210011
申请日：2014-03-13
发明人： Kathleen McMillan
CPC分类号： A61B18/24 , A61B5/01 , A61B2018/00011 , A61B2018/00583 , A61N5/0603 , A61N2005/007 , A61N2005/0606 , A61N2005/063 , A61N2005/0644 , A61N2005/0659 , A61N2005/067
摘要： An apparatus and a method are provided for the treatment of soft tissue. The apparatus includes a light source and at least two optical assemblies. Each of the optical assemblies includes at least one optical element and a light-transmitting contact surface configured to transmit a substantially uniform distribution of light therethrough. The apparatus further includes at least two optical transmission devices each disposed between the light source and a corresponding one of the at least two optical assemblies. The apparatus also includes a handpiece to which the at least two optical assemblies are attached, and which is adapted to bring the light-transmitting contact surfaces of the at least two optical assemblies in contact with soft tissue disposed therebetween. The method includes compressing and substantially flattening portions of the tonsil tissue between light-transmitting contact surfaces of two opposed light emitting optical assemblies, introducing light into an optical element of each of the optical assemblies; and irradiating the tonsil tissue by directing the light from the optical element through the light-transmitting contact surfaces to the tonsil tissue in a substantially uniform light distribution.
摘要翻译： 提供了一种用于治疗软组织的装置和方法。 该装置包括光源和至少两个光学组件。 每个光学组件包括至少一个光学元件和被配置为透射基本均匀的光分布的透光接触表面。 该装置还包括至少两个光传输装置，每个至少两个光传输装置设置在光源和至少两个光学组件中相应的一个之间。 该装置还包括手持件，至少两个光学组件被附接到该手持件，并且其适于使至少两个光学组件的透光接触表面与设置在其间的软组织接触。 该方法包括在两个相对的发光光学组件的透光接触表面之间压扁并扁平化扁桃体组织的部分，将光引入每个光学组件的光学元件中; 并且以基本均匀的光分布将来自光学元件的光引导通过透光接触表面到扁桃体组织来照射扁桃体组织。
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