公开(公告)号：US12035433B2

公开(公告)日：2024-07-09

申请号：US17681738

申请日：2022-02-26

Applicant: Applied BioPhotonics Ltd.

Inventor： Richard K. Williams ,  Keng-Hung Lin ,  Laura E. Williams

IPC: H05B45/325 ,  A61N5/06 ,  H05B45/24 ,  H05B45/36 ,  H05B45/3725 ,  H05B45/375 ,  H05B45/38 ,  H05B45/39 ,  H05B45/397 ,  H05B45/46

CPC classification number: H05B45/325 ,  A61N5/06 ,  H05B45/24 ,  H05B45/3725 ,  H05B45/397 ,  H05B45/46 ,  A61N2005/0626 ,  A61N2005/0651 ,  H05B45/36 ,  H05B45/375 ,  H05B45/38 ,  H05B45/39

Abstract: A phototherapy system includes a channel driver, a first microcontroller and a pad comprising a string of light-emitting diodes (LEDs). The pad also comprises a second microcontroller that autonomously controls the string of LEDs such that the LEDs are controlled even if communication between the first microcontroller and the pad is interrupted.

公开(公告)号：US11109458B2

公开(公告)日：2021-08-31

申请号：US16446862

申请日：2019-06-20

Applicant: Applied BioPhotonics Ltd.

Inventor： Richard K. Williams ,  Keng Hung Lin ,  Daniel Schell ,  Joseph P. Leahy

IPC: A61N5/06 ,  H05B45/36 ,  H05B45/24 ,  H05B45/46 ,  H05B45/20 ,  H05B45/325 ,  H05B45/397

Abstract: The LEDs in a phototherapy LED pad are controlled so that the intensity of the light varies in accordance with a sinusoidal function, thereby eliminating the harmonics that are generated when the LEDs are pulsed digitally. This is accomplished analogically by using a sinusoidal wave to control the gate of a MOSFET connected in series with the LEDs or by using a digital-to-analog converter to control the gate of the MOSFET with a stair step function representative of the values of a sinusoidal function at predetermined intervals. Alternatively, pulse-width modulation is used to control the gate of the MOSFET in such a way that the average current through the LEDs simulates a sinusoidal function. In additional to using a simple sine wave function, the LED current may also be controlled in accordance with “chords” containing multiple sine waves of different frequencies.

公开(公告)号：US20180146520A1

公开(公告)日：2018-05-24

申请号：US15857002

申请日：2017-12-28

Applicant: Applied BioPhotonics Ltd.

Inventor： Richard K. Williams

IPC: H05B33/08 ,  A61N5/06

CPC classification number: H05B33/08 ,  A61N5/06 ,  A61N2005/0626 ,  A61N2005/0651 ,  H05B33/0803 ,  H05B33/0827 ,  H05B33/0866

Abstract: A phototherapy or photobiomodulation process employing the application of electromagnetic radiation (EMR) to a living organism, typically a human being. The EMR is generated by one or more strings of LEDs and is programmed to emit one or more wavelengths, typically in the visible and infrared portions of the spectrum, the EMR in each wavelength being delivered in pulses having specified on-times, off-times, photoexcitation frequencies, duty factors, phase delays, and power amplitudes. A system for providing such EMR includes a microcontroller having a pattern library of algorithms, each of which defines a particular sequence of synthesized pulses, and an application pad, preferably flexible, containing the LED strings.

公开(公告)号：US20220191989A1

公开(公告)日：2022-06-16

申请号：US17681738

申请日：2022-02-26

Applicant: Applied BioPhotonics Ltd.

Inventor： Richard K. Williams ,  Keng-Hung Lin ,  Laura E. Williams

IPC: H05B45/325 ,  A61N5/06 ,  H05B45/24 ,  H05B45/46 ,  H05B45/3725 ,  H05B45/397

Abstract: A phototherapy system includes a channel driver, a first microcontroller and a pad comprising a string of light-emitting diodes (LEDs). The pad also comprises a second microcontroller that autonomously controls the string of LEDs such that the LEDs are controlled even if communication between the first microcontroller and the pad is interrupted.

公开(公告)号：US10328276B2

公开(公告)日：2019-06-25

申请号：US14461147

申请日：2014-08-15

Applicant: Applied BioPhotonics Limited

Inventor： Richard K. Williams ,  Keng Hung Lin ,  Daniel Schell ,  Joseph P. Leahy

IPC: A61N5/06 ,  A61B17/00

Abstract: The LEDs in a phototherapy LED pad are controlled so that the intensity of the light varies in accordance with a sinusoidal function, thereby eliminating the harmonics that are generated when the LEDs are pulsed digitally, in accordance with a square-wave function. This is accomplished analogically by using a sinusoidal wave to control the gate of a MOSFET connected in series with the LEDs or by using a digital-to-analog converter to control the gate of the MOSFET with a stair step function representative of the values of a sinusoidal function at predetermined intervals. Alternatively, pulse-width modulation is used to control the gate of the MOSFET in such a way that the average current through the LEDs simulates a sinusoidal function. In additional to using a simple sine wave function, the LED current may also be controlled in accordance with “chords” containing multiple sine waves of different frequencies.

公开(公告)号：US20180169431A1

公开(公告)日：2018-06-21

申请号：US15893666

申请日：2018-02-11

Applicant: Applied BioPhotonics Ltd

Inventor： Richard K. Williams ,  Keng Hung Lin ,  Yu-Min Lin ,  Daniel Schell ,  Joseph Leahy

IPC: A61N5/06

Abstract: In a flexible LED pad for use in phototherapy treatment of humans or animals, the PCBs in the pad are securely linked together with electrical connectors and ribbon cables to prevent the connections from being broken as the flexible pad is bent or otherwise deformed during the treatment. In one embodiment, low-profile socket connectors are mounted to the PCBs and mate with plug connectors at the ends of the ribbon cables. For similar reasons, the LED pad may be connected to an LED control unit by means of an electrical connector (e.g. a USB socket) mounted to a PCB in the LED pad. The PCBs, on which the LEDs are mounted, are fitted into a downset in the flexible pad to prevent the LEDs from becoming misaligned with openings in the flexible pad.

公开(公告)号：US11388799B2

公开(公告)日：2022-07-12

申请号：US16377181

申请日：2019-04-06

Applicant: Applied BioPhotonics Ltd.

Inventor： Richard K. Williams ,  Keng-Hung Lin ,  Laura E. Williams

IPC: H05B45/00 ,  H05B45/325 ,  A61N5/06 ,  H05B45/24 ,  H05B45/46 ,  H05B45/3725 ,  H05B45/397 ,  H05B45/36 ,  H05B45/375 ,  H05B45/38 ,  H05B45/39

Abstract: A phototherapy system includes a channel driver, a first microcontroller and a pad comprising a string of light-emitting diodes (LEDs). The pad also comprises a second microcontroller that autonomously controls the string of LEDs such that the LEDs are controlled even if communication between the first microcontroller and the pad is interrupted.

公开(公告)号：US11184981B2

公开(公告)日：2021-11-23

申请号：US16055117

申请日：2018-08-05

Applicant: Applied BioPhotonics, Ltd.

Inventor： Richard K Williams ,  Keng Hung Lin

IPC: H05K3/02 ,  H05K3/10 ,  H05K1/14 ,  H05K3/46 ,  H05K3/00 ,  H05K3/06 ,  H05K3/18 ,  H05K3/32 ,  H05K3/36 ,  H05K3/40 ,  H05K3/24

Abstract: A rigid-flex PCB includes an array of rigid PCB “islands” interconnected by a flexible PCB formed into flexible connectors. The conductive and insulating layers of the flexible PCB extend into the rigid PCBs, giving the electrical connections to the rigid PCBs added resistance to breakage as the rigid-flex PCB is repeatedly stressed by bending and twisting forces. In addition, the durability of the rigid-flex PCB is enhanced by making the power and signal lines driving the rigid PCBs redundant so that a breakage of a line will not necessarily affect the operation of the rigid PCB to which it is attached. The rigid-flex PCB is particularly applicable to light pads used in phototherapy, wherein LEDs mounted on the rigid-PCBs are powered and controlled through the redundant lines in the flexible PCB.

公开(公告)号：US11006488B2

公开(公告)日：2021-05-11

申请号：US15857002

申请日：2017-12-28

Applicant: Applied BioPhotonics Ltd.

Inventor： Richard K. Williams

IPC: A61N5/06 ,  H05B33/08 ,  H05B45/00 ,  H05B45/24 ,  H05B45/46

Abstract: A phototherapy or photobiomodulation process employing the application of electromagnetic radiation (EMR) to a living organism, typically a human being. The EMR is generated by one or more strings of LEDs and is programmed to emit one or more wavelengths, typically in the visible and infrared portions of the spectrum, the EMR in each wavelength being delivered in pulses having specified on-times, off-times, photoexcitation frequencies, duty factors, phase delays, and power amplitudes. A system for providing such EMR includes a microcontroller having a pattern library of algorithms, each of which defines a particular sequence of synthesized pulses, and an application pad, preferably flexible, containing the LED strings.

公开(公告)号：US09877361B2

公开(公告)日：2018-01-23

申请号：US14073371

申请日：2013-11-06

Applicant: Richard K. Williams

Inventor： Richard K. Williams

IPC: A61N5/06 ,  A61B18/18 ,  H05B33/08

CPC classification number: H05B33/08 ,  A61N5/06 ,  A61N2005/0626 ,  A61N2005/0651 ,  H05B33/0803 ,  H05B33/0827 ,  H05B33/0866

Abstract: A phototherapy or photobiomodulation process employing the application of electromagnetic radiation (EMR) to a living organism, typically a human being. The EMR is generated by one or more strings of LEDs and is programmed to emit one or more wavelengths, typically in the visible and infrared portions of the spectrum, the EMR in each wavelength being delivered in pulses having specified on-times, off-times, photoexcitation frequencies, duty factors, phase delays, and power amplitudes. A system for providing such EMR includes a microcontroller having a pattern library of algorithms, each of which defines a particular sequence of synthesized pulses, and an application pad, preferably flexible, containing the LED strings.