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公开(公告)号：US07988285B2
公开(公告)日：2011-08-02
申请号：US12628344
申请日：2009-12-01
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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公开(公告)号：US20080033547A1
公开(公告)日：2008-02-07
申请号：US11738062
申请日：2007-04-20
申请人： Shiao Chang , Okihiro Nishi , Kayo Nishi , Jerry Kaeni , Ken Chuang
发明人： Shiao Chang , Okihiro Nishi , Kayo Nishi , Jerry Kaeni , Ken Chuang
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1627 , A61F2/1635
摘要： The invention relates to a intraocular lens system having a flexible anterior lens accommodation material behind the lens. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material. The anterior lens is flexible such that the curvature of the lens changes during accommodation. The anterior lens may be used alone or in combination with a posterior lens.
摘要翻译： 本发明涉及一种在镜片后面具有柔性前透镜容纳材料的眼内透镜系统。 住宿材料可以包括一种或多种大分子单体，当聚合时，调节住宿材料的性质。 前透镜是柔性的，使得在调节期间镜片的曲率改变。 前眼镜可以单独使用或与后视镜组合使用。
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公开(公告)号：US07281795B2
公开(公告)日：2007-10-16
申请号：US11083794
申请日：2005-03-18
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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4.发明申请Composition and method for producing shapable implants in vivo and implants produced thereby 审中-公开用于生产体内可成形植入物的组合物和方法以及由此产生的植入物公开(公告)号：US20070129802A1
公开(公告)日：2007-06-07
申请号：US11598168
申请日：2006-11-10
申请人： Jagdish Jethmalani , Shiao Chang , Robert Grubbs , Julia Kornfield , Daniel Schwartz , Christian Sandstedt , F. Christ
发明人： Jagdish Jethmalani , Shiao Chang , Robert Grubbs , Julia Kornfield , Daniel Schwartz , Christian Sandstedt , F. Christ
CPC分类号： A61F2/16 , A61F2/1613 , A61F2/1616 , A61F2/1627 , A61F2/1635 , A61F2002/1699 , A61L27/14 , A61L27/50 , A61L2430/16 , B29D11/00009 , B29D11/00355 , B29D11/023 , G02C7/02 , G02C2202/14
摘要： The present invention relates to a method for creating shaped implants, such as intraocular lenses in vivo, as well as the novel implants themselves. Utilizing the method of the invention, it is possible to create an implant in vivo and to adjust either the physical properties such as refractive index, viscosity, etc., mechanical properties such as modulus, tensile strength, tear, etc., or the shape of the implant by noninvasive means. For example, using the method of the patent it is possible to create an intraocular lens in vivo and then adjust the shape and power of the lens through no invasion means. The novel implants are also addressed in this application.
摘要翻译： 本发明涉及一种用于产生成形植入物的方法，例如体内的眼内透镜，以及新颖的植入物本身。 利用本发明的方法，可以在体内产生植入物，并且可以调节诸如折射率，粘度等的物理性质，模量，拉伸强度，撕裂等的机械性能或形状 的植入物通过无创手段。 例如，使用该专利的方法，可以在体内产生眼内透镜，然后通过无侵入手段来调整透镜的形状和功率。 本申请中还提到了新颖的植入物。
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公开(公告)号：US20070055369A1
公开(公告)日：2007-03-08
申请号：US11518363
申请日：2006-09-08
申请人： Robert Grubbs , Shiao Chang
发明人： Robert Grubbs , Shiao Chang
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/16 , A61F2002/1696 , A61F2002/16965 , A61K9/0051 , A61L27/34 , G02B5/208
摘要： The invention relates to novel optical elements having improved UV protection. The optical element comprises a light adjustable optical element with a UV absorbent layer applied to at least one surface of the optical element. The invention is particularly useful in light adjustable intraocular lenses.
摘要翻译： 本发明涉及具有改进的UV保护的新型光学元件。 光学元件包括光可调光学元件，其具有施加到光学元件的至少一个表面的UV吸收层。 本发明在光可调眼内透镜中特别有用。
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公开(公告)号：US20070041007A1
公开(公告)日：2007-02-22
申请号：US11517880
申请日：2006-09-08
申请人： Ben Platt , Christian Sandstedt
发明人： Ben Platt , Christian Sandstedt
IPC分类号： G01B9/00
CPC分类号： G02B26/06 , G02B27/0025 , G02B27/0068 , G02B27/58
摘要： A method of correcting aberrations in an optical system by applying a light adjustable aberration conjugator layer to a component of the system, determining the nature of the aberration, applying radiation to the conjugator layer such as to change the refraction and/or shape of the conjugator layer to compensate for the aberration, and locking in the desired optical property.
摘要翻译： 一种校正光学系统中的像差的方法，该方法是通过将光可调像差共轭器层应用于该系统的一个部件，确定像差的性质，向共轭层施加辐射，以改变共轭体的折射和/或形状 层以补偿像差，并锁定所需的光学性质。
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公开(公告)号：US06917416B2
公开(公告)日：2005-07-12
申请号：US10784656
申请日：2004-02-23
CPC分类号： G02B26/06 , G02B27/0025 , G02B27/0068 , G02B27/58
摘要： A method of correcting aberrations in an optical system by applying a light adjustable aberration conjugator layer to a component of the system, determining the nature of the aberration, applying radiation to the conjugator layer such as to change the refraction and/or shape of the conjugator layer to compensate for the aberration, and locking in the desired optical property.
摘要翻译： 一种校正光学系统中的像差的方法，通过将光可调像差共轭器层应用到系统的一个部件上，确定像差的性质，向共轭层施加辐射，以改变共轭器的折射和/或形状 层以补偿像差，并锁定所需的光学性质。
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公开(公告)号：US20160339657A1
公开(公告)日：2016-11-24
申请号：US15159909
申请日：2016-05-20
申请人： Calhoun Vision, Inc.
CPC分类号： B29D11/00461 , A61F2/1627 , A61F2/1635 , A61F2/1659 , A61F2002/16965 , B29D11/023 , B29K2683/00
摘要： A method for adjusting a light adjustable lens in an optical system includes providing a light adjustable lens in an optical system; providing an ultraviolet light source to generate an ultraviolet light; and irradiating the generated ultraviolet light with a light delivery system onto the light adjustable lens with a center wavelength and with a spatial irradiance profile to change a dioptric power of the light adjustable lens by changing a refraction of the light adjustable lens in a refraction-change zone, thereby causing a wavefront sag, defined as half of a product of the change of the dioptric power and the square of a radius of the refraction-change zone, to be within 10% of its maximum over an ultraviolet spectrum.
摘要翻译： 一种用于调整光学系统中的可调光透镜的方法包括在光学系统中提供光可调透镜; 提供紫外光源以产生紫外光; 以及将具有光输送系统的所产生的紫外光照射到具有中心波长和空间辐照度分布的光调节透镜上，以通过在折射变化中改变光可调透镜的折射来改变光可调透镜的屈光度 区域，从而导致定义为屈光度的变化率和折射变化区域的半径的平方的乘积的一半的波前凹陷在紫外光谱的10％以内。
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公开(公告)号：US20160113761A1
公开(公告)日：2016-04-28
申请号：US14988973
申请日：2016-01-06
申请人： CALHOUN VISION, INC.
发明人： Okihiro Nishi , Kayo Nishi , Shiao H. Chang , Jerry Kaeni
CPC分类号： A61F2/1648 , A61F2/1613 , A61F2/1627 , A61F2/1635 , A61F9/0017 , A61F9/007 , A61F2002/1699 , A61F2002/30581 , A61F2002/30583 , A61F2210/0085 , A61L27/18 , A61L27/50 , A61L2430/16 , C08L83/04
摘要： The invention relates to a multi-lens intraocular lens system having an accommodation material between the lenses. The system comprises an posterior lens attached to the posterior surface of the capsular bag and an anterior lens attached to the anterior surface of the capsular bag. The anterior and posterior lenses have different optical properties providing different degrees and types of correction. An accommodation material is place between the anterior and posterior lenses. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material.
摘要翻译： 本发明涉及一种在透镜之间具有调节材料的多透镜眼内透镜系统。 该系统包括附接到囊袋后表面的后透镜和附接到囊袋前表面的前透镜。 前后透镜具有不同的光学特性，提供不同程度和类型的校正。 住宿材料位于前后透镜之间。 住宿材料可以包括一种或多种大分子单体，当聚合时，调节住宿材料的性质。
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10.发明授权Method for making novel compositions capable of post fabrication modification 有权制备能够进行后制造改性的新型组合物的方法公开(公告)号：US08361353B2
公开(公告)日：2013-01-29
申请号：US11486615
申请日：2006-07-14
申请人： Axel Brait , Shiao H. Chang , Patrick Case
发明人： Axel Brait , Shiao H. Chang , Patrick Case
CPC分类号： B05D5/06 , A61F2/1627 , G02B1/041 , C08L83/04 , C08L79/00 , C08L33/08 , C08L33/10 , C08L85/02
摘要： The invention relates to a novel method for preparing materials whose properties can be manipulated after fabrication. In this process, a base material is created in a manner that provides spaces or voids which can then be filled with a modifying composition. The method is particularly useful in the manufacture of light adjustable optical elements such as intraocular lenses.
摘要翻译： 本发明涉及一种制备材料的新方法，其制造后可以操作其性能。 在该方法中，以提供空间或空隙的方式产生基材，然后可以用改性组合物填充基材。 该方法在制造可调光学元件如眼内透镜中特别有用。
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