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公开(公告)号：US10905571B2
公开(公告)日：2021-02-02
申请号：US16035497
申请日：2018-07-13
申请人： Nellix, Inc.
摘要： Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.
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公开(公告)号：US09814612B2
公开(公告)日：2017-11-14
申请号：US14697433
申请日：2015-10-21
申请人： NELLIX, INC.
发明人： Charles S. Taylor , Christopher Zarins , Robert A. Geshlider , Dwight P. Morejohn , Peter Johansson , Susan W. Vican , James T. McKinley
CPC分类号： A61F2/958 , A61F2/07 , A61F2002/061 , A61F2002/065 , A61F2002/077 , A61F2230/0069 , A61F2240/002 , A61F2250/0003
摘要： A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.
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公开(公告)号：US20090319029A1
公开(公告)日：2009-12-24
申请号：US12478208
申请日：2009-06-04
申请人： Michael A. Evans , Ivan Tzvetanov , Steven L. Herbowy , Raj P. Ganpath , Amy Lee , Anant Kumar , Gwendolyn A. Watanabe , K.T. Venkateswara Rao
发明人： Michael A. Evans , Ivan Tzvetanov , Steven L. Herbowy , Raj P. Ganpath , Amy Lee , Anant Kumar , Gwendolyn A. Watanabe , K.T. Venkateswara Rao
CPC分类号： A61F2/954 , A61F2/07 , A61F2/82 , A61F2/89 , A61F2/90 , A61F2/958 , A61F2002/067 , A61F2002/077 , A61F2220/0058 , A61F2220/0075 , A61F2230/0034
摘要： A system for treating an aneurysm in a blood vessel comprises a docking scaffold having with upstream and downstream ends, and a central passageway therebetween. The upstream end engages the blood vessel upstream of the aneurysm. A portion of a first and second scaffolds are slidably received in the central passageway such that an outside surface of the first and second scaffolds engage an inside surface of the docking scaffold. A double-walled filling structure has outer and inner walls and the filling structure is adapted to be filled with a hardenable fluid filling medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow therethrough. The double-walled filling structure is coupled with at least one of the first and second leg scaffolds in expanded configuration.
摘要翻译： 用于治疗血管中的动脉瘤的系统包括具有上游和下游端的停放构架以及它们之间的中心通路。 上游端接合动脉瘤上游的血管。 第一和第二支架的一部分可滑动地容纳在中央通道中，使得第一和第二支架的外表面接合对接支架的内表面。 双壁填充结构具有外壁和内壁，并且填充结构适于填充可硬化流体填充介质，使得外壁符合动脉瘤的内表面，并且内壁形成基本上管状的腔，以提供 血流通过的路径。 双壁填充结构与第一和第二腿支架中的至少一个以扩展构型联接。
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公开(公告)号：US07530988B2
公开(公告)日：2009-05-12
申请号：US11187471
申请日：2005-07-22
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2002/075 , A61F2002/077 , A61F2230/0034 , A61F2250/0003
摘要： Aneurysms are treated by filling a double-walled filling structure with a curable medium. The structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. The filling structures are preferably used in pairs for providing flow into the iliac arteries when treating abdominal aortic aneurysm.
摘要翻译： 通过用可固化培养基填充双壁填充结构来处理动脉瘤。 结构可以在气囊展开机构上传送，以便通过其形成和打开管状流明。 填充结构优选成对使用，以在治疗腹主动脉瘤时提供流入髂动脉的流体。
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公开(公告)号：US20210212699A1
公开(公告)日：2021-07-15
申请号：US17157379
申请日：2021-01-25
申请人： Nellix, Inc.
发明人： Steven L. Herbowy , Michael A. Evans , Anant Kumar , K.T. Venkateswara Rao , Matthew R. Hellewell , Gil Laroya
摘要： A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other.
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公开(公告)号：US09737425B2
公开(公告)日：2017-08-22
申请号：US14537749
申请日：2014-11-10
申请人： NELLIX, INC.
CPC分类号： A61F2/958 , A61B17/12118 , A61B17/12136 , A61B17/12195 , A61B2017/1205 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/067 , A61F2002/077 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/005 , A61F2250/0003 , A61M2025/0002
摘要： Methods and systems for treating aneurysms using filling structures filled with a curable medium are described herein. Such methods can include positioning a double-walled filling structure across the aneurysm and filling with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device during and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint.
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公开(公告)号：US08906084B2
公开(公告)日：2014-12-09
申请号：US12684074
申请日：2010-01-07
CPC分类号： A61F2/958 , A61B17/12118 , A61B17/12136 , A61B17/12195 , A61B2017/1205 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/067 , A61F2002/077 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/005 , A61F2250/0003 , A61M2025/0002
摘要： Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
摘要翻译： 实施例提供了使用填充有可固化介质的填充结构来治疗动脉瘤的方法和系统。 方法的一个实施例包括将至少一个双壁填充结构定位在动脉瘤上并用填充介质填充结构，使得外壁符合动脉瘤的内部，并且内壁形成大致管状的内腔 提供血流量。 管腔在填充时和/或填充后用气囊或其他可扩张装置支撑。 监测结构内的压力和/或在结构的外壁和动脉瘤壁之间的空间中的压力，并且响应于压力控制介质流入结构的流动。 压力也可用于确定灌装终点。 当腔保持气球支撑时，介质硬化。 培养基硬化后，取出球囊。
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8.发明授权Graft systems having filling structures supported by scaffolds and methods for their use 有权具有由支架支撑的填充结构的移植系统及其使用方法公开(公告)号：US08870941B2
公开(公告)日：2014-10-28
申请号：US13285897
申请日：2011-10-31
CPC分类号： A61F2/844 , A61F2/07 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/077 , A61F2230/0034 , A61F2250/0003 , A61F2250/0069
摘要： Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.
摘要翻译： 通过在动脉瘤内填充至少一个具有可固化培养基的双壁填充结构来治疗动脉瘤。 填充结构可以在气囊展开机构上传送，以形成和打开通过其中的管状流明。 将脚手架放置在管状内腔中，以帮助保持形状，将填充结构锚定在适当位置，并且提供进入和离开管状内腔的改善的血流过渡。
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9.发明申请公开(公告)号：US20110208042A1
公开(公告)日：2011-08-25
申请号：US13100483
申请日：2011-05-04
申请人： Amy Lee , Michael A. Evans
发明人： Amy Lee , Michael A. Evans
IPC分类号： A61B6/00
CPC分类号： A61F2/82 , A61F2240/001 , A61L31/10 , A61L31/129 , A61L31/18 , Y10T428/1352 , Y10T428/2495 , Y10T428/249955 , Y10T428/249958 , Y10T428/3154 , Y10T428/31544 , Y10T428/31551 , Y10T428/31938 , C08L27/18
摘要： The present invention provides multilayered materials, such as films usable in particular in medical devices in the form of vascular grafts, biocompatible coverings, and/or inflatable bladders, prosthesis for the endoluminal treatment of aneurysms, particularly aortic aneurysms including both abdominal aortic aneurysms (AAA's) and thoracic aortic aneurysms (TAA's).
摘要翻译： 本发明提供多层材料，例如可用于血管移植物形式的医疗装置，生物相容性覆盖物和/或可膨胀气囊的膜，用于腔内治疗动脉瘤的假体，特别是包括腹主动脉瘤的主动脉瘤（AAA's ）和胸主动脉瘤（TAA's）。
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10.发明申请公开(公告)号：US20100312267A1
公开(公告)日：2010-12-09
申请号：US12858274
申请日：2010-08-17
申请人： Amy Lee , Michael A. Evans
发明人： Amy Lee , Michael A. Evans
IPC分类号： A61M29/00
CPC分类号： A61F2/82 , A61F2240/001 , A61L31/10 , A61L31/129 , A61L31/18 , Y10T428/1352 , Y10T428/2495 , Y10T428/249955 , Y10T428/249958 , Y10T428/3154 , Y10T428/31544 , Y10T428/31551 , Y10T428/31938 , C08L27/18
摘要： The present invention provides multilayered materials, such as films usable in particular in medical devices in the form of vascular grafts, biocompatible coverings, and/or inflatable bladders, prosthesis for the endoluminal treatment of aneurysms, particularly aortic aneurysms including both abdominal aortic aneurysms (AAA's) and thoracic aortic aneurysms (TAA's).
摘要翻译： 本发明提供多层材料，例如可用于血管移植物形式的医疗装置，生物相容性覆盖物和/或可膨胀气囊的膜，用于腔内治疗动脉瘤的假体，特别是包括腹主动脉瘤的主动脉瘤（AAA's ）和胸主动脉瘤（TAA's）。
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