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公开(公告)号：US5977126A
公开(公告)日：1999-11-02
申请号：US79002
申请日：1998-05-14
IPC分类号： A61K31/58 , A61P5/26 , A61P43/00 , C07C235/82 , C07J3/00 , C07J41/00 , C07J73/00 , C07J75/00 , A61K31/435
CPC分类号： C07J3/005 , C07C235/82 , C07J41/0066 , C07J73/005 , C07C2103/14
摘要： The present invention relates to methods for preparing and using compounds of formula (I), wherein carbons 1 and 2 are joined by either a single or a double bond; R.sup.1 is hydrogen or methyl; R.sup.2 is hydrogen or methyl; R.sup.3 is (A) wherein X, W, Z, R.sup.4, and R.sup.5, are various groups, and pharmaceutically acceptable solvates thereof and their use in the treatment of androgen responsive and mediated diseases.
摘要翻译： 本发明涉及制备和使用式（I）化合物的方法，其中碳1和2通过单键或双键连接; R1是氢或甲基; R2是氢或甲基; R3是（A）其中X，W，Z，R4和R5是各种基团，以及其药学上可接受的溶剂合物及其在治疗雄激素应答和介导的疾病中的用途。
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2.发明授权Photoelectric conversion material, film containing the material, photoelectric conversion device, production method thereof, photosensor, imaging device and their use methods 有权光电转换材料，含有该材料的膜，光电转换装置，其制造方法，光电传感器，成像装置及其使用方法公开(公告)号：US09035055B2
公开(公告)日：2015-05-19
申请号：US12877264
申请日：2010-09-08
IPC分类号： C07D221/22 , C07C223/06 , C07C225/22 , C07D209/86 , C07D213/74 , C07D219/02 , C07D221/18 , C07D223/14 , C07D239/62 , C07D239/66 , C07D307/66 , C07D333/36 , C07D495/04 , H01L27/30 , H01L51/00 , H01L51/42 , C09B23/04 , C09B57/00
CPC分类号： C07C223/06 , C07C225/22 , C07C2102/08 , C07C2103/14 , C07C2103/18 , C07C2103/24 , C07C2103/26 , C07C2103/50 , C07C2602/08 , C07C2603/14 , C07C2603/18 , C07C2603/24 , C07C2603/26 , C07C2603/50 , C07D209/86 , C07D213/74 , C07D219/02 , C07D221/18 , C07D223/14 , C07D239/62 , C07D239/66 , C07D307/66 , C07D333/36 , C07D495/04 , C09B23/04 , C09B57/008 , H01L27/307 , H01L51/006 , H01L51/4253 , Y02E10/549
摘要： An organic compound and a photoelectric conversion device containing the organic compound are disclosed. The organic compound and device realize high photoelectric conversion efficiency, low dark current and high-speed responsivity. It has been found that when this organic compound and an n-type semiconductor are used in combination, high-speed responsivity can be realized while maintaining high heat resistance, an aspect of which has not been seen when the connection part between a donor part and an acceptor part is a phenylene group.
摘要翻译： 公开了含有有机化合物的有机化合物和光电转换装置。 有机化合物和器件实现高光电转换效率，低暗电流和高速响应。 已经发现，当组合使用该有机化合物和n型半导体时，可以在保持高耐热性的同时实现高速响应性，当施主部分和供体部分之间的连接部分 受体部分是亚苯基。
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公开(公告)号：US5565467A
公开(公告)日：1996-10-15
申请号：US405120
申请日：1995-03-16
CPC分类号： C07J3/005 , C07C235/82 , C07J41/0066 , C07J73/005 , C07C2103/14
摘要： The present invention relates to the compound of formula (I), ##STR1## also known as 17.beta.-N-(2,5-bis(Trifluoromethyl))phenylcarbamoyl-4-aza-5.alpha.-androst-1-en-3-one, solvates thereof, its preparation, intermediates used in its preparation, pharmaceutical formulations thereof and its use in the treatment of androgen responsive and mediated diseases.
摘要翻译： 本发明涉及式（I）化合物，也称为17β-N-（2,5-双（三氟甲基））苯基氨基甲酰基-4-氮杂-5α-雄甾-1-烯酸的化合物， en-3-酮，其溶剂合物，其制备，其制备中使用的中间体，其药物制剂及其在治疗雄激素反应性和介导性疾病中的用途。
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公开(公告)号：US4808632A
公开(公告)日：1989-02-28
申请号：US79352
申请日：1987-07-30
申请人： Kenneth W. Bair
发明人： Kenneth W. Bair
IPC分类号： C07C215/10
CPC分类号： C07C215/10 , C07C2103/14 , C07C2103/24 , C07C2103/26 , C07C2103/40 , C07C2103/48 , C07C2103/50 , Y10S514/908
摘要： The present invention relates to compounds of formula (I)ArCH.sub.2 R.sup.1 (I)or a monomethyl or a monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters thereof; acid addition salts thereof; wherein Ar is a fluoranthene or substituted fluoranthene ring system; R.sup.1 contains not more than eight carbon atoms and is a group ##STR1## wherein m is 0 or 1; R.sup.5 is hydrogen;R.sup.6 and R.sup.7 are the same or different and each is hydrogen or C.sub.1-3 alkyl optionally substituted by hydroxy;R.sup.8 and R.sup.9 are the same or different and each is hydrogen or C.sub.1-3 alkyl; ##STR2## is a five- or six-membered saturated carbocyclic ring; R.sup.10 is hydrogen, methyl or hydroxymethyl;R.sup.11, R.sup.12 and R.sup.13 are the same or different and each is hydrogen or methyl;R.sup.14 is hydrogen, methyl, hydroxy, or hydroxymethyl.
摘要翻译： 本发明涉及式（I）化合物，其中ArCH 2 R 1（I）或其单甲醚或单乙醚（包括这些醚的式（I）化合物总共可含有不超过30个碳原子）; 醚，酯; 其酸加成盐; 其中Ar是荧蒽或取代的荧蒽环体系; R1含有不多于8个碳原子，并且是一个基团，其中m是0或1; R5是氢; R6和R7相同或不同，各自为氢或任选被羟基取代的C 1-3烷基; R 8和R 9相同或不同，各自为氢或C 1-3烷基; 一个五元或六元饱和碳环; R 10是氢，甲基或羟甲基; R11，R12和R13相同或不同，各自为氢或甲基; R14是氢，甲基，羟基或羟甲基。
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公开(公告)号：US5846976A
公开(公告)日：1998-12-08
申请号：US708167
申请日：1996-08-22
CPC分类号： C07J3/005 , C07C235/82 , C07J41/0066 , C07J73/005 , C07C2103/14
摘要： The present invention relates to the compound of formula (I), ##STR1## also known as 17.beta.-N-(2,5-bis(Trifluoromethyl))phenylcarbamoyl-4-aza-5.alpha.-androst-1-en-3-one, solvates thereof, its preparation, intermediates used in its preparation, pharmaceutical formulations thereof and its use in the treatment of androgen responsive and mediated diseases.
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公开(公告)号：US3956316A
公开(公告)日：1976-05-11
申请号：US427753
申请日：1973-12-26
IPC分类号： C07C59/215 , C07C59/80 , C07C309/65 , C07C309/66 , C07C309/73 , C07D317/44 , C07C49/38 , C07C69/14 , C07D317/72
CPC分类号： C07C59/80 , C07C309/65 , C07C309/66 , C07C309/73 , C07C59/215 , C07C2103/14 , C07C2103/16
摘要： This invention is directed to 11-substituted-desA-pregnanes and derivatives thereof which are useful as intermediates in the production of 9.beta.,10.alpha.-known steroids of the pregnane series. These latter compounds can be utilized as progestational and salt-retaining agents.
摘要翻译： 本发明涉及11-取代-deA-孕烷及其衍生物，其可用作制备孕甾烷酮系列的9β，10α-已知类固醇的中间体。 这些后一种化合物可以用作孕激素和保留盐。
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公开(公告)号：US09593061B2
公开(公告)日：2017-03-14
申请号：US14887298
申请日：2015-10-19
CPC分类号： C07C67/343 , C07C45/64 , C07C45/67 , C07C45/78 , C07C45/81 , C07C67/31 , C07C67/333 , C07C2103/14 , C07C47/565 , C07C47/575 , C07C69/92 , C07C69/84
摘要： The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin derivatives, such as treprostinil.
摘要翻译： 本公开内容提供了用于合成可用于制备前列环素衍生物（例如曲前列素）的中间体的区域选择性方法。
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公开(公告)号：US20160107973A1
公开(公告)日：2016-04-21
申请号：US14887298
申请日：2015-10-19
IPC分类号： C07C51/353 , C07C67/30 , C07C45/71 , C07C67/343 , C07C45/67 , C07C67/34
CPC分类号： C07C67/343 , C07C45/64 , C07C45/67 , C07C45/78 , C07C45/81 , C07C67/31 , C07C67/333 , C07C2103/14 , C07C47/565 , C07C47/575 , C07C69/92 , C07C69/84
摘要： The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin derivatives, such as treprostinil.
摘要翻译： 本公开提供了用于合成可用于制备前列环素衍生物（例如曲前列素）的中间体的区域选择性方法。
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9.发明申请PHOTOELECTRIC CONVERSION MATERIAL, FILM CONTAINING THE MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR USE METHODS 有权光电转换材料，包含材料的薄膜，光电转换装置，其制造方法，光电子发射器，成像装置及其使用方法公开(公告)号：US20110056562A1
公开(公告)日：2011-03-10
申请号：US12877264
申请日：2010-09-08
IPC分类号： H01L31/04 , C07C211/58 , C07C211/61 , C07D213/74 , C07D221/18 , H01L31/18
CPC分类号： C07C223/06 , C07C225/22 , C07C2102/08 , C07C2103/14 , C07C2103/18 , C07C2103/24 , C07C2103/26 , C07C2103/50 , C07C2602/08 , C07C2603/14 , C07C2603/18 , C07C2603/24 , C07C2603/26 , C07C2603/50 , C07D209/86 , C07D213/74 , C07D219/02 , C07D221/18 , C07D223/14 , C07D239/62 , C07D239/66 , C07D307/66 , C07D333/36 , C07D495/04 , C09B23/04 , C09B57/008 , H01L27/307 , H01L51/006 , H01L51/4253 , Y02E10/549
摘要： A compound represented by the following formula (I), and a photoelectric conversion device containing the compound: wherein Z1 is a ring containing two carbon atoms and represents a 5-membered ring, a 6-membered ring or a condensed ring containing at least either a 5-membered ring or a 6-membered ring, each of L1, L2 and L3 independently represents an unsubstituted methine group or a substituted methine group, n represents an integer of 0 or more, each of R1, R2, R3, R4, R5 and R6 independently represents a hydrogen atom or a substituent, R1 and R2, R2 and R3, R4 and R5, or R5 and R6 may be combined with each other to form a ring, and each of R21 and R22 independently represents a substituted aryl group, an unsubstituted aryl group, a substituted heteroaryl group or an unsubstituted heteroaryl group, provided that the case where both R21 and R22 are an unsubstituted phenyl group is excluded.
摘要翻译： 由下式（I）表示的化合物和含有该化合物的光电转换装置：其中Z1是含有两个碳原子并且表示5元环的环，6元环或稠环，其至少包含 5元环或6元环，L1，L2和L3各自独立地表示未取代的次甲基或取代的次甲基，n表示0以上的整数，R 1，R 2，R 3，R 4， R5和R6独立地表示氢原子或取代基，R1和R2，R2和R3，R4和R5或R5和R6可以相互结合形成环，R 21和R 22各自独立地表示取代的芳基 基团，未取代的芳基，取代的杂芳基或未取代的杂芳基，条件是R 21和R 22均为未取代的苯基的情况除外。
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公开(公告)号：US4661522A
公开(公告)日：1987-04-28
申请号：US734049
申请日：1985-05-15
申请人： Tom Beetz
发明人： Tom Beetz
IPC分类号： A61K31/155 , C07C20060101 , C07C123/00
CPC分类号： C07C259/16 , C07C2103/10 , C07C2103/14 , C07C2103/16
摘要： The present invention is dealing with cycloalkane-indene-carboximidamide derivatives having the general formula: ##STR1## wherein Rx together with either Ry.sub.1 or Ry.sub.2 represent the moiety ##STR2## (the other Ry being hydrogen), n represents the number 1, 2 or 3,R represents hydrogen or a (1-4 C)-alkyl group,R.sub.1 represents hydrogen, (1-4 C)-alkyl, hydroxyl, (1-4 C)-alkoxy or an amino group which is unsubstituted or substituted by (1-4 C)-alkyl andR.sub.2 is hydrogen, hydroxyl or (1-4 C)-alkyl, as well as the pharmaceutically acceptable salts thereof, with powerful blood platelet aggregation-inhibiting activity.
摘要翻译： 本发明涉及具有以下通式的环烷 - 茚 - 肟基亚胺酰胺衍生物：其中Rx与Ry1或Ry2一起代表部分（另一个Ry是氢），n代表数字1,2或 3，R表示氢或（1-4C） - 烷基，R1表示氢，（1-4C） - 烷基，羟基，（1-4C） - 烷氧基或未取代或被 （1-4C） - 烷基和R2是氢，羟基或（1-4C） - 烷基，以及其药学上可接受的盐，具有强大的血小板聚集抑制活性。
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