TERPENE SYNTHASES FROM SANTALUM
    3.
    发明申请
    TERPENE SYNTHASES FROM SANTALUM 审中-公开
    来自SANTALUM的TERPENE SYNTHASES

    公开(公告)号:US20150167021A1

    公开(公告)日:2015-06-18

    申请号:US14628125

    申请日:2015-02-20

    IPC分类号: C12P5/00 C12P15/00 C12N9/88

    摘要: An isolated nucleic acid molecule that encodes a terpene synthase and is selected from among: a) a nucleic acid molecule comprising the sequence of nucleotides set forth in SEQ ID NO: 1, SEQ ID NO: 3 or SEQ ID NO: 5; b) a nucleic acid molecule that is a fragment of (a); c) a nucleic acid molecule comprising a sequence of nucleotides that is complementary to (a) or (b); and d) a nucleic acid molecule that encodes a terpene synthase having at least or at least about 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, 99% identity to any one of (a)-(c); wherein the nucleic acid molecule encodes a terpene synthase.

    摘要翻译: 编码萜烯合酶的分离的核酸分子,其选自:a)包含SEQ ID NO:1,SEQ ID NO:3或SEQ ID NO:5所示核苷酸序列的核酸分子; b)作为(a)的片段的核酸分子; c)包含与(a)或(b)互补的核苷酸序列的核酸分子; 和d)编码具有至少约至少约60%,65%,70%,75%,80%,85%,90%,95%,96%,97%,98的萜烯合酶的核酸分子 (a) - (c)中任何一个的%,99%同一性; 其中所述核酸分子编码萜烯合酶。

    METHOD FOR PRODUCING BETA-SANTALENE
    5.
    发明申请

    公开(公告)号:US20180105837A1

    公开(公告)日:2018-04-19

    申请号:US15688956

    申请日:2017-08-29

    申请人: Firmenich SA

    发明人: Michel SCHALK

    IPC分类号: C12P5/00 C12N9/88

    摘要: The present invention provides a method of producing β-santalene, said method comprising contacting at least one polypeptide with farnesyl pyrophosphate (FPP). In particular, said method may be carried out in vitro or in vivo to produce β-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing said nucleic acid are also part of the present invention. A non-human host organism or a cell transformed to be used in the method of producing β-santalene is also an object of the present invention.

    METHOD FOR PRODUCING BETA-SANTALENE
    6.
    发明申请
    METHOD FOR PRODUCING BETA-SANTALENE 审中-公开
    生产苯乙烯的方法

    公开(公告)号:US20150176029A1

    公开(公告)日:2015-06-25

    申请号:US14530651

    申请日:2014-10-31

    申请人: FIRMENICH SA

    发明人: Michel SCHALK

    IPC分类号: C12P5/00 C12N9/88

    摘要: The present invention provides a method of producing β-santalene, said method comprising contacting at least one polypeptide with farnesyl pyrophosphate (FPP). In particular, said method may be carried out in vitro or in vivo to produce β-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing said nucleic acid are also part of the present invention. A non-human host organism or a cell transformed to be used in the method of producing β-santalene is also an object of the present invention.

    摘要翻译: 本发明提供了一种生产皂苷的方法,所述方法包括使至少一种多肽与焦亚磷酸法呢基(FPP)接触。 特别地,所述方法可以在体外或体内进行以产生在香料和香料领域中非常有用的化合物。 本发明还提供了可用于本发明方法的多肽的氨基酸序列。 编码本发明多肽的核酸和含有该核酸的表达载体也是本发明的一部分。 非人类宿主生物体或转化用于生产ant al烯的方法的细胞也是本发明的目的。

    MODIFIED SANTALENE SYNTHASE POLYPEPTIDES, ENCODING NUCLEIC ACID MOLECULES AND USES THEREOF
    8.
    发明申请
    MODIFIED SANTALENE SYNTHASE POLYPEPTIDES, ENCODING NUCLEIC ACID MOLECULES AND USES THEREOF 有权
    改性的SANTALENE SYNTHASE POLYPEPTIES,编码核酸分子及其用途

    公开(公告)号:US20150275196A1

    公开(公告)日:2015-10-01

    申请号:US14673720

    申请日:2015-03-30

    申请人: ALLYLIX, INC.

    IPC分类号: C12N9/88 C12P5/00

    摘要: Provided are modified santalene synthase polypeptides, nucleic acid molecules encoding the modified santalene synthase polypeptides, and methods of using the modified santalene synthase polypeptides. The modified santalene synthase polypeptides include those that catalyze production of increased levels of terpenes or altered profiles thereof or both.

    摘要翻译: 提供了修饰的樟脑烯合酶多肽,编码修饰的檀香烃合酶多肽的核酸分子,以及使用修饰的檀香烃合酶多肽的方法。 修饰的樟脑烯合酶多肽包括那些催化萜烯增加水平的产生或其改变的分布或两者的那些。

    Method for producing beta-santalene
    9.
    发明授权
    Method for producing beta-santalene 有权
    β-檀香草生产方法

    公开(公告)号:US08877461B2

    公开(公告)日:2014-11-04

    申请号:US13124866

    申请日:2009-12-09

    申请人: Michel Schalk

    发明人: Michel Schalk

    IPC分类号: C12P21/06

    摘要: A method of producing β-santalene by contacting at least one polypeptide with farnesyl pyrophosphate (FPP). This method may be carried out in vitro or in vivo to produce β-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing the nucleic acid are also disclosed, along with a non-human host organism or a cell transformed to be used in the method of producing β-santalene.

    摘要翻译: 通过使至少一种多肽与法呢基焦磷酸酯(FPP)接触来生产β-花生四烯的方法。 该方法可以在体外或体内进行以产生在香料和香料领域中非常有用的化合物。 本发明还提供了可用于本发明方法的多肽的氨基酸序列。 还公开了编码本发明多肽的核酸和含有该核酸的表达载体,以及非人宿主生物体或转化用于生产β-花生四烯的方法的细胞。

    Terpene Synthases From Santalum
    10.
    发明申请
    Terpene Synthases From Santalum 有权
    萜烯合成酶

    公开(公告)号:US20140196166A1

    公开(公告)日:2014-07-10

    申请号:US13998045

    申请日:2013-09-24

    摘要: An isolated nucleic acid molecule that encodes a terpene synthase and is selected from among: a) a nucleic acid molecule comprising the sequence of nucleotides set forth in SEQ ID NO: 1, SEQ ID NO: 3 or SEQ ID NO: 5; b) a nucleic acid molecule that is a fragment of (a); c) a nucleic acid molecule comprising a sequence of nucleotides that is complementary to (a) or (b); and d) a nucleic acid molecule that encodes a terpene synthase having at least or at least about 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, 99% identity to any one of (a)-(c); wherein the nucleic acid molecule encodes a terpene synthase.

    摘要翻译: 编码萜烯合酶的分离的核酸分子,其选自:a)包含SEQ ID NO:1,SEQ ID NO:3或SEQ ID NO:5所示核苷酸序列的核酸分子; b)作为(a)的片段的核酸分子; c)包含与(a)或(b)互补的核苷酸序列的核酸分子; 和d)编码具有至少约至少约60%,65%,70%,75%,80%,85%,90%,95%,96%,97%,98的萜烯合酶的核酸分子 (a) - (c)中任何一个的%,99%同一性; 其中所述核酸分子编码萜烯合酶。