公开(公告)号：US06641577B2

公开(公告)日：2003-11-04

申请号：US09997167

申请日：2001-11-28

Applicant: Josef Bille

Inventor： Josef Bille

IPC: A61F9008

CPC classification number: A61F9/008 ,  A61F9/00836 ,  A61F2009/00848 ,  A61F2009/00872

Abstract: A method for creating a corneal flap for use in a corneal reshaping procedure includes the step of creating a periphery for the flap by subsurface photoablation of the cornea using a laser beam. Specifically, tissue located at the interface between layers of stromal lamellae is photoablated to create the periphery. To accomplish this, the size of the bubbles created during photoablation are monitored using a wavefront detector and the photoablation depth is altered when the bubble size indicates that photoablation is not occurring at an interface. With the periphery established, an incision is made into the cornea extending between the anterior surface of the cornea and the periphery. Next, the corneal tissue bounded by the incision is lifted to mechanically separate the flap from the remainder of the cornea along the interface between layers of lamellae.

Abstract translation: 用于创建用于角膜重塑过程的角膜瓣的方法包括通过使用激光束的角膜的次表面光消融来为瓣片创建外周的步骤。 具体地，位于基质片层之间的界面处的组织被光照化以产生周边。 为了实现这一点，使用波前检测器来监测在光致消除期间产生的气泡的大小，并且当气泡大小表示在界面处没有发生光消除时，光消除深度被改变。 在外围建立的情况下，在角膜前表面和周边之间形成角膜切口。 接下来，由切口限定的角膜组织被提升以将薄片与片层的其余部分沿着薄片层之间的界面机械分离。

公开(公告)号：US06673061B2

公开(公告)日：2004-01-06

申请号：US10055920

申请日：2002-01-28

Applicant: Hitoshi Abe

Inventor： Hitoshi Abe

IPC: A61F9008

CPC classification number: A61F9/00821 ,  A61B2017/00017 ,  A61B2017/00181 ,  A61F9/008 ,  A61F2009/00863

Abstract: There is disclosed a laser treatment apparatus used for performing treatment on a treatment part of a patient's eye by irradiating the treatment part with a laser beam for treatment. This apparatus includes a treatment beam irradiation optical system for irradiating the treatment beam, the system including a mirror which reflects the treatment beam toward the treatment part; a mirror moving device for moving the mirror to change a point to be irradiated by the treatment beam; and a detector for detecting motion of the mirror.

Abstract translation: 公开了一种激光治疗装置，其通过用处理用激光束照射治疗部，对患者眼睛的治疗部进行治疗。 该装置包括用于照射处理束的处理束照射光学系统，该系统包括将处理光束反射到处理部分的反射镜; 镜子移动装置，用于移动反射镜以改变被处理光束照射的点; 以及用于检测反射镜的运动的检测器。

公开(公告)号：US06312423B1

公开(公告)日：2001-11-06

申请号：US09317108

申请日：1999-05-24

Applicant: Yasuo Ota ,  Tokio Ueno

Inventor： Yasuo Ota ,  Tokio Ueno

IPC: A61F9008

CPC classification number: A61F9/008 ,  A61B2018/2025 ,  A61F9/00821 ,  A61F9/009 ,  A61F9/023 ,  A61F2009/00863 ,  A61F2009/00874 ,  A61F2009/00887

Abstract: In a laser treatment apparatus, a treatment laser beam emitted from a laser source 10 is coaxially aligned to an aiming beam emitted from an aiming light source 18 by a beam splitter 20. The coaxial beams are delivered to a patient's eye E through a light delivery optical system, when a controller 60 controls an inclination angle of a filter 57 to change its spectral characteristics such that the filter cuts off the treatment laser beam during the treatment laser irradiation, while allows to the aiming beam to pass during the observation of the patient's eye.

Abstract translation: 在激光治疗装置中，从激光源10发射的治疗激光束与由分束器20从瞄准光源18发射的瞄准光束同轴对准。同轴光束通过光传送被传送到患者眼睛E 光学系统，当控制器60控制过滤器57的倾斜角度以改变其光谱特性，使得过滤器在处理激光照射期间切断处理激光束，同时允许瞄准光束在观察患者的过程中通过 眼。

公开(公告)号：US06726679B1

公开(公告)日：2004-04-27

申请号：US10069607

申请日：2002-02-25

Applicant: Manfred Dick ,  Eckhard Schroeder

Inventor： Manfred Dick ,  Eckhard Schroeder

IPC: A61F9008

CPC classification number: A61F9/008 ,  A61B90/20 ,  A61B2017/00154 ,  A61B2017/00172 ,  A61F9/00736 ,  A61F9/00825 ,  A61F9/00838 ,  A61F9/0084 ,  A61F9/009 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00874 ,  A61F2009/00887 ,  A61F2009/00895

Abstract: The present invention relates to a method and a device for treating opacities and/or hardenings of an unopened eye. It is a specific advantage of the solution according to the invention that the treamtment of the inner region of the eye is possible without the need to introduce a surgical instrument into the eye.

Abstract translation: 本发明涉及一种用于治疗未开封眼睛的不透明度和/或硬化的方法和装置。根据本发明的解决方案的特别优点在于可以在眼睛的内部区域进行切割，而不需要 将手术器械引入眼睛。

公开(公告)号：US06322554B1

公开(公告)日：2001-11-27

申请号：US09431101

申请日：1999-11-01

Applicant: Seiki Tomita

Inventor： Seiki Tomita

IPC: A61F9008

CPC classification number: A61F9/008 ,  A61F9/00821 ,  A61F2009/00863 ,  A61F2009/0087 ,  A61F2009/00874 ,  A61F2009/00887 ,  A61F2009/00889

Abstract: A laser treatment apparatus for irradiating an affected area of a patient with a treatment laser beam is disclosed. In the apparatus, the treatment laser beam is emitted by a laser source and delivered to the affected area through a treatment laser beam irradiation optical system to irradiate the affected area. An aiming light delivery optical system forms plural aiming light beams so that an optical axis of the treatment laser beam irradiation optical system is put between the aiming light beams, and delivers the plural aiming light beams to the affected area so that the aiming light beams are focused on a position on which the treatment laser beam is to be focused. During this focusing, the aiming beams are being rotated manually or automatically by a manual rotation mechanism or an automatic rotation mechanism. The rotating mode of the aiming beams is selected with a selection switch from a manual rotation mode and an automatic rotation mode.

Abstract translation: 公开了一种用于用治疗激光束照射病人的受影响区域的激光治疗装置。 在该装置中，处理激光束由激光源发射并通过处理激光束照射光学系统传送到受影响的区域以照射受影响的区域。 瞄准光输送光学系统形成多个瞄准光束，使得处理激光束照射光学系统的光轴位于瞄准光束之间，并将多个瞄准光束传送到受影响的区域，使得瞄准光束 集中在待处理激光束聚焦的位置上。 在该聚焦期间，瞄准光束通过手动旋转机构或自动旋转机构手动或自动旋转。 瞄准光束的旋转模式由手动旋转模式和自动旋转模式的选择开关选择。

公开(公告)号：US06251101B1

公开(公告)日：2001-06-26

申请号：US09105073

申请日：1998-06-26

Applicant: Herrmann J. Glockler

Inventor： Herrmann J. Glockler

IPC: A61F9008

CPC classification number: A61F9/008 ,  A61B90/20 ,  A61F9/00804 ,  A61F2009/00872

Abstract: The invention provides improved structures, systems, and methods for supporting the optical elements of a microscope relative to the optical train of a laser surgery system. As the field of view of the microscope is substantially fully determined by the position of the objective lens, the laser delivery optics and the microscope can be aligned with a target location of the patient's eye by accurately aligning just the objective lens with the delivery optics. By structurally separating the objective lens from the other optical components of the microscope, and by maintaining accurate alignment between the objective lens and the laser delivery optics with a simple, tight-tolerance support structure, the remaining optical components of the microscope can be allowed to “float” relative to the objective lens with a looser-tolerance without degrading the operator's ability to align, observe, and optically direct an ophthalmic laser procedure.

Abstract translation: 本发明提供了用于支持显微镜相对于激光手术系统的光学系列的光学元件的改进的结构，系统和方法。 由于显微镜的视野基本上完全由物镜的位置确定，因此可以通过精确地将物镜与输送光学器件对准，激光输送光学器件和显微镜可以与患者眼睛的目标位置对准。 通过将物镜与显微镜的其他光学部件结构地分离，并且通过简单的，容错的支撑结构保持物镜和激光输送光学元件之间的精确对准，可以允许显微镜的剩余的光学部件 相对于物镜“宽”相对容易，而不会降低操作者对眼睛激光程序进行对准，观察和光学指导的能力。

公开(公告)号：US06679876B2

公开(公告)日：2004-01-20

申请号：US09982780

申请日：2001-10-22

Applicant: Naoyuki Kondo ,  Kazunobu Kojima ,  Satoshi Imaizumi

Inventor： Naoyuki Kondo ,  Kazunobu Kojima ,  Satoshi Imaizumi

IPC: A61F9008

CPC classification number: A61F9/008 ,  A61F9/00804 ,  A61F9/00817 ,  A61F2009/00872

Abstract: The present invention is intended to provide a corneal surgery apparatus which enables a surgical operator to accurately ablate a cornea in part. The corneal surgery apparatus for ablating part of a cornea by irradiating a laser beam onto the cornea of a patient's eye comprises an irradiation optical system for irradiating the laser beam emitted from a laser light source onto the cornea, an aperture, which is disposed in the irradiation optical system, profiling a cross-sectional region of the beam perpendicular to an optical axis of the irradiation into one or more small regions, and correcting device for correcting an intensity distribution of the laser beam, which is changed when the beam passes through the aperture, to a specified intensity distribution.

Abstract translation: 本发明旨在提供一种角膜外科手术装置，其使得外科手术人员能够部分地准确地消融角膜。 用于通过将激光束照射到患者眼睛的角膜上来消融部分角膜的角膜手术装置包括用于将从激光光源发射的激光束照射到角膜上的照射光学系统，其设置在 照射光学系统，将垂直于照射光轴的光束的横截面区域成像为一个或多个小区域，以及校正装置，用于校正激光束的强度分布，该装置在光束通过 孔径，达到指定的强度分布。

公开(公告)号：US06322556B1

公开(公告)日：2001-11-27

申请号：US08103089

申请日：1993-08-06

Applicant: Arlene E. Gwon ,  Michael W. Berns

Inventor： Arlene E. Gwon ,  Michael W. Berns

IPC: A61F9008

CPC classification number: A61F9/008 ,  A61F9/00736 ,  A61F9/00802 ,  A61F2009/00853 ,  A61F2009/0087 ,  A61F2009/00887 ,  A61F2009/00895

Abstract: A method for the laser photoablation of ocular lens tissue comprises the steps of determining a volume of the lens tissue to be photoablated and directing a pulsed, infrared laser beam at the volume with an amount of energy effective for photoablating the determined region without causing substantial damage to surrounding tissue regions. The laser beam is initially directed at a focal point below an anterior surface of the ocular lens and such focal point is moved towards the ocular lens anterior surface in order to ablate the determined volume. The laser is preferably an Nd:YLF laser operating at a frequency of about 1053 nanometers and a pulse repetition rate of about 1000 Hertz with a pulse width of about 60 picoseconds. Each pulse has an energy of about 30 microjoules. The laser operates with a focused beam diameter of about 20 microns and operates with a “zone of effect” of no greater than about 50 microns. The method provides for the correction of myopia, hyperopia or presbyopia and enables the removal of incipient cataract.

Abstract translation: 用于眼透镜组织的激光光切割的方法包括以下步骤：确定要光照的透镜组织的体积，并以一定量的能量对脉冲的红外激光束进行照射，以有效地对确定的区域进行照相，而不会造成实质的损伤 到周围的组织区域。 激光束最初被引导到眼透镜的前表面下方的焦点处，并且这样的焦点朝向眼透镜前表面移动以便消融确定的体积。 该激光器优选为以约1053纳米的频率工作的Nd：YLF激光器，脉冲重复率约为1000赫兹，脉冲宽度约为60皮秒。 每个脉冲具有约30微焦耳的能量。 激光器以约20微米的聚焦光束直径进行操作，并以不大于约50微米的“效应区域”操作。 该方法提供矫正近视，远视或老花眼，并能够去除早期白内障。

公开(公告)号：US06217571B1

公开(公告)日：2001-04-17

申请号：US09397148

申请日：1999-09-16

Applicant: Gholam A. Peyman

Inventor： Gholam A. Peyman

IPC: A61F9008

CPC classification number: A61F9/013 ,  A61F2/147 ,  A61F9/00804 ,  A61F9/00812 ,  A61F9/00817 ,  A61F9/00821 ,  A61F2009/00872

Abstract: Methods for modifying a live cornea to correct a patient's vision. In the case of hyperopia, at least one slit is first made in the cornea for inserting a knife, a fiber optic cable or micro-cutting tool therein to separate an internal area of the cornea into first and second opposed internal surfaces such that a substantially circular area centered about the main optical axis of the cornea remains attached between the first and second internal surfaces. The laser beam or micro-cutting tool can be directed onto one of the first and second internal surfaces, or both, if needed or desired to incrementally and sequentially remove three-dimensional portions of the cornea. If a laser beam is used, then a flexible template can be inserted between the internal surfaces of the cornea for accurately controlling the pattern to be ablated within the cornea. In the case of myopia, instead of removing intrastromal tissue, ocular material can be introduced between the internal surfaces to change the patient's vision. The ocular material can be either a fluid or a solid lens or a combination thereof. In either case, the ocular material is transparent or translucent material with either a refractive index substantially the same as the intrastromal tissue of the cornea, or a different refractive index from the intrastromal tissue of the cornea.

Abstract translation: 修改活角膜以纠正患者视力的方法。 在远视的情况下，首先在角膜中形成至少一个狭缝，用于将刀，光纤电缆或微切割工具插入其中以将角膜的内部区域分离为第一和第二相对的内表面，使得基本上 围绕角膜的主光轴居中的圆形区域保持附接在第一和第二内表面之间。 如果需要或期望激光束或微切割工具可以被引导到第一和第二内表面中的一个或两者上，以逐渐地和顺序地移除角膜的三维部分。 如果使用激光束，则可以在角膜的内表面之间插入柔性模板，以精确控制角膜内要消融的图案。 在近视的情况下，可以在内表面之间引入眼部材料，而不是去除内部组织，以改变患者的视力。 眼部材料可以是流体或实心透镜或其组合。 在任一种情况下，眼部材料都是透明或半透明的材料，其折射率与角膜的体内组织基本相同，或者与角膜的基质内组织不同的折射率。

公开(公告)号：US06770068B2

公开(公告)日：2004-08-03

申请号：US10207947

申请日：2002-07-31

Applicant: Antonio Ruiz ,  Eduardo Matallana

Inventor： Antonio Ruiz ,  Eduardo Matallana

IPC: A61F9008

CPC classification number: G03F7/70291 ,  A61F9/007

Abstract: An electro-optical patternable mask is provided which is controllable by way of a processor for presenting a variety of patterns to electromagnetic radiation. In one embodiment of the mask, the electro-optical mask includes an electrochromic layer that works in conjunction with deposited electrode layers (at least one with an x-y pixel array) to present a pattern of non-transmission (colored) and transmission (bleached clear) pixel cells. The sandwiched electrochromic material is supported in one embodiment with a UV grade support substrate with the electrochromic cells of the mask being individually (e.g., individual cells or small groups of individual cells in an array) controlled by a processor and interface to achieve a sequence of different or the same patterns to achieve desired ablation volume upon transmitting ultraviolet energy through the mask such as in conjunction with an opthalmic laser surgery process. In an alternate embodiment a substrate-dispersed liquid crystal material is used in the mask as the means for controlling the transmission of electromagnetic energy such as ultraviolet light of a pulsed laser. An electro-optical device featuring a stacked, preferably monolithic multiple substrate dispersed liquid crystal layer member is also described to ensure blockage of ultraviolet light that hits a pixel cell. The multi-series or multi-stacked substrate dispersed liquid crystal material cell has its field states controlled with electric field generating device which mainains an intermediate substrate-dispersed layer with an electric field across it while the outer substrate dispersed liquid crystal layers can be switched from a no field-blockage mode to an electric-field on full transmission through cell mode. The multi-stack or series electro-optical device is useful as a mask pixel cell as well as in a variety of other field involving wavelength across the visible and ultraviolet spectrum, for example. The various mask embodiments provide a reusable controllable mask well suited for ablation processes such as corneal resurfacing using an opthamological laser surgery (e.g., LASIK) system. The electro-optical mask of the present invention provides for rapid large beam application with a smooth and high precision ablation.