公开(公告)号：US06375847B1

公开(公告)日：2002-04-23

申请号：US09254045

申请日：1999-03-01

申请人： Eduard Hartmann

发明人： Eduard Hartmann

IPC分类号： B01D6122

CPC分类号： B01D61/12 ,  B01D61/22

摘要： The method relates to the operation of a cross-flow filtration installation for a product. This installation includes a filtration module (6), a pipeline (3) for the inflow of the product, a pipeline (9) for removing the product, a pump (4) with an electric motor (12) for recirculating the product, and a control valve (5′) for setting the conveying flow (Q1) of the pump (4). In order to make possible the maximally possible filtration output, based on the installation, along with a high proportion of solids of the product, without endangering operational safety by means of overloads, the strength of the operating current (i1) of the electric motor (12) is measured. The operating current (i1) is adjusted to a maximally, permissible value via a regulator (20) by setting the conveying flow (Q1) of the pump (4) by adjusting the flow control valve (5′).

摘要翻译： 该方法涉及用于产品的交叉流过滤装置的操作。 该安装包括过滤模块（6），用于产品流入的管道（3），用于移出产品的管道（9），具有用于使产品再循环的电动机（12）的泵（4），以及 用于设定泵（4）的输送流（Q1）的控制阀（5'）。 为了实现最大可能的过滤输出，基于安装，以及高比例的产品固体，而不会通过过载危及操作安全性，电动机的工作电流（i1）的强度（i1） 12）。 通过调节流量控制阀（5'），通过调节泵（4）的输送流量（Q1），通过调节器（20）将工作电流（i1）调节到最大允许值。

公开(公告)号：US06730227B2

公开(公告)日：2004-05-04

申请号：US10109260

申请日：2002-03-28

申请人： E. H. Kelle Zeiher ,  Bosco P. Ho ,  John E. Hoots

发明人： E. H. Kelle Zeiher ,  Bosco P. Ho ,  John E. Hoots

IPC分类号： B01D6122

CPC分类号： B01D65/102 ,  B01D61/12 ,  B01D61/22 ,  B01D61/54 ,  C02F1/441

摘要： Methods and systems for monitoring and/or controlling membrane separation systems or processes are provided. The present invention utilizes measurable amounts of inert fluorescent tracers and tagged fluorescent agents added to a feed stream to evaluate and/or control one or more parameters specific to membrane separation such that performance thereof can be optimized. The methods and systems of the present invention can be utilized in a variety of different industrial applications including raw water processing and waste water processing.

公开(公告)号：US06602424B1

公开(公告)日：2003-08-05

申请号：US09469605

申请日：1999-12-22

申请人： Matthias Krämer ,  Carsten Müller ,  Christian Johner

发明人： Matthias Krämer ,  Carsten Müller ,  Christian Johner

IPC分类号： B01D6122

CPC分类号： A61M1/16 ,  A61M1/1613 ,  A61M1/1635 ,  A61M1/3403 ,  A61M1/341 ,  A61M1/3413 ,  A61M1/361 ,  A61M1/3613 ,  A61M2205/18 ,  A61M2205/50 ,  Y10S210/929

摘要： To increase the safety of an extracorporeal blood treatment machine which has control of the ultrafiltration rate as a function of the blood volume of the patient, the ultrafiltration rate UFR(t) during the treatment is monitored in a safety device. The safety device has a computer unit for determining an upper limit for the ultrafiltration rate UFRlim from the predetermined total ultrafiltrate volume UFVtot and the predetermined treatment time UFT. The safety device also has a monitoring unit with which the ultrafiltration rate is limited to the upper limit determined by the computer unit so that any risk to the patient is prevented even in the case of faulty blood volume control.

摘要翻译： 为了提高控制作为患者体内血容量的超滤速度的体外血液处理机的安全性，在安全装置中监视处理过程中的超滤率UFR（t）。 安全装置具有用于根据预定的总超滤体积UFVtot和预定处理时间UFT确定超滤率UFRlim的上限的计算机单元。 安全装置还具有监测单元，超滤速率被限制到由计算机单元确定的上限，使得即使在血量控制不正确的情况下也能够防止对患者的任何风险。

公开(公告)号：US06821428B1

公开(公告)日：2004-11-23

申请号：US10109256

申请日：2002-03-28

申请人： E. H. Kelle Zeiher ,  Bosco P. Ho ,  John E. Hoots ,  Binaifer S. Bedford ,  Martin R. Godfrey

发明人： E. H. Kelle Zeiher ,  Bosco P. Ho ,  John E. Hoots ,  Binaifer S. Bedford ,  Martin R. Godfrey

IPC分类号： B01D6122

CPC分类号： B01D65/102 ,  B01D61/12 ,  B01D61/22 ,  B01D61/54 ,  C02F1/441

摘要： Methods and systems for monitoring and/or controlling membrane separation systems or processes are provided. The present invention utilizes measurable amounts of inert fluorescent tracer(s) added to a feed stream to evaluate and/or control the purification of such feed stream during membrane separation. The methods and systems of the present invention can be utilized in a variety of different industrial applications including raw water processing and waste water processing.

公开(公告)号：US06270671B1

公开(公告)日：2001-08-07

申请号：US09478839

申请日：2000-01-07

申请人： Jacob Shorr ,  John Paul Toohil

发明人： Jacob Shorr ,  John Paul Toohil

IPC分类号： B01D6122

CPC分类号： C02F1/444 ,  B01D61/147 ,  B01D61/16 ,  B01D69/14 ,  B01D2311/04 ,  B01D2311/12 ,  B01D2311/14 ,  B01D2311/16 ,  B01D2311/18

摘要： A method and apparatus for microfiltration useful in softening water as well as in removing other dissolved constituents where the method comprises passing water that contains a precipitate through a semipermeable tubular membrane. Filtrate is received from the outside of the tubular membrane and the filtrate contains levels of dissolved compounds at concentrations below those that would be predicted by the solubility limits of the compounds. The method may be practiced at elevated pressures and turbulent flow without incurring significant fouling of the membrane. It is particularly suited to removing cations such as calcium and magnesium that contribute to water hardness. The water may be treated prior to passing through the membrane by adjusting pH, adding complimentary anions, or adding a flocculant. The apparatus comprises a series of semipermeable tubular membranes housed in a module. The membranes are fluidly connected to an inlet and two outlets. A momentary dynamic membrane is disposed on the inner surface of the tubular membrane.

摘要翻译： 用于软化水以及去除其它溶解成分的微滤的方法和装置，其中所述方法包括使含有沉淀物的水通过半透性管状膜。 从管状膜的外部接收滤液，并且滤液含有浓度低于化合物的溶解度极限预测的浓度的溶解化合物。 该方法可以在升高的压力和湍流下实施，而不会引起膜的显着结垢。 特别适用于除去有助于水硬度的阳离子如钙和镁。 可以在通过调节pH值，加入互补阴离子或添加絮凝剂之前，先对水进行处理。 该装置包括容纳在模块中的一系列半透性管状膜。 膜流体连接到入口和两个出口。 瞬时动态膜设置在管状膜的内表面上。

公开(公告)号：US06780322B1

公开(公告)日：2004-08-24

申请号：US10030011

申请日：2002-06-11

申请人： John J. Bissler ,  Marios M. Polycarpou ,  Nat Hemasilpin ,  Efrain O. Morales

发明人： John J. Bissler ,  Marios M. Polycarpou ,  Nat Hemasilpin ,  Efrain O. Morales

IPC分类号： B01D6122

CPC分类号： G05B13/0275 ,  A61M1/16 ,  A61M1/1603 ,  A61M1/1605 ,  A61M1/1611 ,  A61M1/1615 ,  A61M1/1643 ,  A61M1/1647 ,  A61M1/34 ,  A61M1/341 ,  A61M1/3413 ,  A61M1/342 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/3451 ,  A61M1/3496 ,  A61M1/3607 ,  A61M1/3639 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3393 ,  A61M2205/50 ,  Y10S210/929

摘要： A multipurpose hemofiltration system (10) and method are disclosed for the removal of fluid and/or soluble waste from the blood of a patient. The system (10) continuously monitors the flow rates of drained fluid, blood, and infusate. When necessary, the pumping rates of the infusate, drained fluid and blood are adjusted to remove a preselected amount of fluid from the blood in a preselected time period. A supervisory controller (160) can monitor patient parameters, such as heart rate (120) and blood pressure (130), and adjust the pumping rates accordingly. The supervisory controller (160) uses fuzzy logic to make expert decisions, based upon a set of supervisory rules, to control each pumping rate to achieve a desired flow rate and to respond to fault conditions. An adaptive controller (162) corrects temporal variations in the flow rate based upon an adaptive law and a control law.

摘要翻译： 公开了用于从患者的血液中除去流体和/或可溶性废物的多用途血液滤过系统（10）和方法。 系统（10）连续监测排出的流体，血液和灌注液的流量。 必要时，调节输注液，排出的液体和血液的泵送速率，以在预选的时间段内从血液中除去预选量的流体。 监督控制器（160）可以监测诸如心率（120）和血压（130）的患者参数，并相应地调节泵送速率。 监督控制器（160）使用模糊逻辑基于一组监督规则来做出专家决定，以控制每个泵送速率以实现期望的流速并对故障状况做出响应。 自适应控制器（162）基于自适应规律和控制律来校正流量的时间变化。

公开(公告)号：US06733676B2

公开(公告)日：2004-05-11

申请号：US10076488

申请日：2002-02-19

申请人： Ichiro Takai

发明人： Ichiro Takai

IPC分类号： B01D6122

CPC分类号： A61M1/16 ,  A61M1/1605 ,  A61M1/3403 ,  A61M1/3639 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2230/30

摘要： A dialyzing system comprises a dialyzer 10 and an ultrafiltration-regulating unit 24 for regulating inflow and out flow of a dialysate to or from the dialyzer 10 to regulate ultrafiltration. The dialyzing system is adapted to determine a blood pressure from a dialysate pressure detected by a pressure transducer 28 at the time of temporary suspension of the ultrafiltration without use of a special line for measurement of pressure in the blood flow line and free from danger of blood leakage from the blood flow line.

摘要翻译： 透析系统包括透析器10和超滤调节单元24，用于调节透析液到透析器10或从透析器10流出和流出流量以调节超滤。 透析系统适于在暂时停止超滤时确定由压力传感器28检测到的透析液压力的血压，而不使用用于测量血流管线中的压力的​​特殊线路并且没有血液的危险 从血流线泄漏。

公开(公告)号：US06402954B1

公开(公告)日：2002-06-11

申请号：US08980779

申请日：1997-12-01

申请人： Patrick J. O'Keefe, Jr.

发明人： Patrick J. O'Keefe, Jr.

IPC分类号： B01D6122

CPC分类号： B01D61/22 ,  B01D65/02 ,  B01D2321/16

摘要： A method and apparatus for optimizing the filtration of process fluid. The system provides establishing a peak flow rate of permeate through a filter and then engaging a filtering cycle in which process fluid is passed through the filter until such time as the flow rate of permeate through the filter reaches a predetermined level which is set as a function of the initial permeate flow rate. At that point in time, a cleaning cycle is entered, during which cleaning fluid is passed through the filter for such a period of time as is necessary to allow the permeate flow rate with the cleaning solution to stabilize. At that point in time, the processing of process fluid is recommenced and the process continues on a repetitive basis between the processing of process fluid and the cleaning of the filter.

摘要翻译： 一种优化过程流体过滤的方法和装置。 该系统提供了通过过滤器的渗透物的峰值流速，然后接合过滤循环，其中过程流体通过过滤器，直到渗透通过过滤器的流量达到设定为功能的预定水平 的初始渗透流量。 在该时间点，进入清洁循环，在此期间清洁流体通过过滤器达到如此一段时间，以允许清洁溶液的渗透流量稳定。 在该时间点，重新处理过程流体，并且在处理流体的处理和过滤器的清洁之间重复地继续处理过程。