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公开(公告)号:US5270199A
公开(公告)日:1993-12-14
申请号:US831619
申请日:1992-02-06
IPC分类号: A61K38/00 , A61K47/48 , C07K14/47 , C12N1/21 , C12Q1/68 , C12N5/00 , C12N15/00 , C12N7/00 , C12N1/16 , C12N1/18 , C12P21/02 , C12P19/34 , C02K3/00 , C07H15/12
CPC分类号: A61K47/48238 , C07K14/4726 , C12Q1/6876 , A61K38/00 , C07K2319/02 , C07K2319/24 , C07K2319/33
摘要: Purified human mannose-binding protein and fragments thereof, nucleic acid producing these fragments, and vectors and cells including such nucleic acid are disclosed. The peptides and antibodies to those peptides are useful for diagnosis and treatment of disease.
摘要翻译: 公开了纯化的人甘露糖结合蛋白及其片段,产生这些片段的核酸,以及包含这种核酸的载体和细胞。 这些肽的肽和抗体可用于疾病的诊断和治疗。
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公开(公告)号:US06863837B2
公开(公告)日:2005-03-08
申请号:US10212470
申请日:2002-08-05
CPC分类号: C04B28/14 , B01F17/0057 , C04B24/22 , C04B28/04 , C04B2103/30 , C04B2103/408 , C08G8/10 , C08G16/0293
摘要: The present invention provides a sulfonated coal tar distillate salt polymer that is a condensation product of an aldehyde, preferably formaldehyde, and a sulfonated middle fraction obtained during coal tar distillation. The middle fraction includes from about 40% to about 95% by weight naphthalene and from about 5% to about 60% by weight of a plurality of compounds selected from the group consisting of quinoline, indene, biphenyl, indane, acenaphthene, anthracene, phenanthrene, methyl naphthalene, cresol, phenol, xylenol, and tetralin. The present invention also provides a method of forming a sulfonated coal tar distillate salt polymer. The method includes sulfonating the middle fraction to form a middle fraction sulfonic acid mass, optionally adding a first portion of water to the middle fraction sulfonic acid mass to form a mixture, reacting the mixture and an aldehyde to form a condensate, optionally adding a second portion of water to dilute the condensate, and adding a base to form a sulfonated middle fraction salt polymer. Sulfonated middle fraction salt polymers formed in accordance with the method of the invention are useful as dispersants and plasticizers in aqueous cementitious slurries.
摘要翻译: 本发明提供了一种磺化煤焦油馏出物盐聚合物,其是醛,优选甲醛和在煤焦油蒸馏期间获得的磺化中间馏分的缩合产物。 中间馏分包括约40重量%至约95重量%的萘和约5重量%至约60重量%的多种选自喹啉,茚,联苯,茚满,苊,蒽,菲的化合物 ,甲基萘,甲酚,苯酚,二甲苯酚和四氢化萘。 本发明还提供形成磺化煤焦油馏出物盐聚合物的方法。 该方法包括磺化中间馏分以形成中间部分磺酸物质,任选地将中间馏分磺酸物质的第一部分水加入以形成混合物,使混合物和醛反应形成冷凝物,任选地加入第二部分 部分水稀释冷凝物,并加入碱形成磺化的中间部分盐聚合物。 根据本发明方法形成的磺化中间馏分盐聚合物可用作水性水泥浆中的分散剂和增塑剂。
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公开(公告)号:US5444155A
公开(公告)日:1995-08-22
申请号:US757442
申请日:1991-09-10
IPC分类号: C12N15/02 , C07B53/00 , C07K16/44 , C12N5/10 , C12N9/00 , C12N15/09 , C12P21/08 , C12R1/91 , A61K35/14 , C12N5/00 , C02K3/00
CPC分类号: C12N9/0002 , C07B53/00
摘要: Monoclonal antibodies or paratope-containing portions thereof are disclosed that immunoreact with a meso diester substrate ligand and catalytically hydrolyze a single predetermined ester bond to form one of a pair of enantiomers. Methods of making and using the same are also disclosed.
摘要翻译: 公开了具有内消旋二酯底物配体的免疫反应并催化水解单一预定酯键以形成一对对映异构体之一的单克隆抗体或其包含其相似的部分。 还公开了制备和使用它们的方法。
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