公开(公告)号：US11685702B2

公开(公告)日：2023-06-27

申请号：US17113695

申请日：2020-12-07

申请人： JSI Silicone Co.

发明人： Il Nam Jung ,  A Ra Cho ,  Seung Hwan Kang ,  Young Min Kim

IPC分类号： C07C2/86 ,  C07C17/266 ,  C07C15/50 ,  C07C15/58 ,  C07C25/24 ,  C07C15/60 ,  C07C45/69 ,  C07C49/796 ,  C07C15/62 ,  C07C43/285 ,  C07C41/30 ,  C07C15/24 ,  C07C15/16 ,  C07C15/20 ,  C07F7/18 ,  C07C319/20 ,  C07C321/28 ,  C07F7/12 ,  C07C15/44

CPC分类号： C07C2/861 ,  C07C15/16 ,  C07C15/20 ,  C07C15/24 ,  C07C15/44 ,  C07C15/50 ,  C07C15/58 ,  C07C15/60 ,  C07C15/62 ,  C07C17/266 ,  C07C25/24 ,  C07C41/30 ,  C07C43/285 ,  C07C45/69 ,  C07C49/796 ,  C07C319/20 ,  C07C321/28 ,  C07F7/12 ,  C07F7/127 ,  C07F7/1804 ,  C07F7/1892 ,  C07C2603/24 ,  C07C2603/50 ,  C07C2603/52

摘要： Provided is a method for producing (alkyl)arene compounds represented by Formulae 3-1, 3-2, and 3-3 by the Friedel-Crafts alkylation reaction of alkyl halide compounds and arene compounds using organic phosphine compounds as a catalyst.

公开(公告)号：US20180318456A1

公开(公告)日：2018-11-08

申请号：US15884833

申请日：2018-01-31

申请人： Lantheus Medical Imaging, Inc.

发明人： Richard R. Cesati ,  Heike S. Radeke ,  Suresh K. Pandey ,  Ajay Purohit ,  Simon P. Robinson

IPC分类号： A61K51/04 ,  C07D237/16 ,  C07D237/14 ,  C07D401/12 ,  C07D311/56 ,  C07F7/12 ,  C07B59/00 ,  C07D403/12 ,  C07D237/04 ,  B01J19/24 ,  A61K49/00 ,  C07F7/08

CPC分类号： A61K51/0459 ,  A61K49/0004 ,  B01J19/24 ,  B01J2219/24 ,  C07B59/002 ,  C07B2200/05 ,  C07D237/04 ,  C07D237/14 ,  C07D237/16 ,  C07D311/56 ,  C07D401/12 ,  C07D403/12 ,  C07F7/0812 ,  C07F7/12

摘要： The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.

公开(公告)号：US20180222928A1

公开(公告)日：2018-08-09

申请号：US15587819

申请日：2017-05-05

申请人： Government of The United States as Represented by the Secretary of the Air Force

发明人： Scott Iacono ,  Abby Rose Jennings

IPC分类号： C07F7/21 ,  C07F7/12 ,  C07F7/18 ,  C07C323/17 ,  C07C43/247 ,  C07C43/192

CPC分类号： C07F7/21 ,  C07C43/192 ,  C07C43/247 ,  C07C323/17 ,  C07C2601/10 ,  C07F7/12 ,  C07F7/1804

摘要： Fluorinated cyclopentene moieties and fluorinated cyclopentene functionalized silica materials are provided. The fluorinated cyclopentene functionalized silica materials include a silica material having the fluorinated cyclopentene moiety covalently bonded thereto. Exemplary silica materials include a polysilsesquioxane, a nanosilica, a microsilica, a silica gel, a silica aerogel, or combinations thereof. The fluorinated cyclopentene moieties are based on a modification of perfluorocyclopentene (i.e., 1,2,3,3,4,4,5,5-octafluoro-1-cyclopentene) by nucleophilic substitution with an appropriate nucleophile having a reactive functional group. Methods for preparing fluorinated cyclopentene moieties and the corresponding fluorinated cyclopentene functionalized silica materials are also provided.

公开(公告)号：US20180186818A1

公开(公告)日：2018-07-05

申请号：US15736677

申请日：2016-06-14

申请人： UBE INDUSTRIES, LTD.

发明人： Noriaki IWASE ,  Yasuhiro AGA ,  Shigeru USHIYAMA ,  Shigeyuki KONO ,  Hidetoshi SUNAMOTO ,  Takashi MATSUSHITA ,  Sayaka OGI ,  Satoshi UMEZAKI ,  Masahiro KOJIMA ,  Kazuhiro ONUMA ,  Yusuke SHIRAISHI ,  Makoto OKUDO ,  Tomio KIMURA

IPC分类号： C07F7/08 ,  A61P35/00 ,  A61K31/695 ,  A61K45/06

CPC分类号： C07F7/0812 ,  A61K31/695 ,  A61K45/06 ,  A61P35/00 ,  C07F7/10 ,  C07F7/12

摘要： The present invention provides a compound represented by the general formula (Ia) or a pharmacologically acceptable salt thereof. In the general formula (Ia), two R moieties each independently represent a C1-3 alkyl group or the like; and R1, R2 and R3 each independently represent an optionally substituted linear or branched C1-4 alkyl group.

公开(公告)号：US20180149654A1

公开(公告)日：2018-05-31

申请号：US15572295

申请日：2016-05-13

申请人： ECONOUS SYSTEMS INC.

发明人： Brian De La Franier ,  Michael Thompson

IPC分类号： G01N33/574 ,  G01N33/92 ,  C07F7/12

CPC分类号： G01N33/57449 ,  C07F7/12 ,  G01N33/57442 ,  G01N33/57488 ,  G01N33/6872 ,  G01N33/92 ,  G01N2333/4703 ,  G01N2333/4712 ,  G01N2333/4727 ,  G01N2405/04 ,  G01N2610/00

摘要： The present disclosure relates to biosensors, kits and methods for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample such as a serum sample from a subject. The present disclosure also relates to linker compounds that are useful, for example, in the biosensors, kits and methods of the present disclosure and to methods for preparing a biosensor for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample.

公开(公告)号：US09917328B2

公开(公告)日：2018-03-13

申请号：US14374734

申请日：2013-02-04

申请人： Silatronix, Inc.

发明人： José Adrián Peña Hueso ,  Jian Dong ,  Michael L. Pollina ,  Monica L. Usrey ,  Robert J. Hamers ,  Robert C. West ,  David Osmalov

IPC分类号： H01M10/0567 ,  C07F7/12 ,  H01M10/052 ,  H01M10/0564 ,  C07F7/08 ,  H01M4/131 ,  H01M10/0525 ,  H01M10/0565 ,  H01M4/02

CPC分类号： H01M10/0567 ,  C07F7/0838 ,  C07F7/12 ,  C07F7/123 ,  H01M4/131 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/0564 ,  H01M10/0565 ,  H01M2004/028 ,  H01M2300/0025 ,  H01M2300/0065

摘要： Described are electrolyte compositions having at least one salt and at least one compound selected from the group consisting of: wherein “a” is from 1 to 3; “b” is 1 or 2; 4≧“a”+“b”≧2; X is a halogen; R can be alkoxy or substituted alkoxy, among other moieties, and R1 is alkyl, substituted alkyl, aryl, substituted aryl, alkoxy, or substituted alkoxy. Also described are electrochemical devices that use the electrolyte composition.

公开(公告)号：US09853321B2

公开(公告)日：2017-12-26

申请号：US15219952

申请日：2016-07-26

申请人： Silatronix, Inc.

发明人： Jose Pena Hueso ,  David Osmalov ,  Jian Dong ,  Monica Usrey ,  Michael Pollina ,  Robert C. West

IPC分类号： C07F7/10 ,  C07F7/12 ,  H01M10/0569 ,  H01M10/056 ,  H01M10/0525 ,  H01G11/58 ,  H01G11/60 ,  C07F7/08 ,  C07F7/18 ,  H01G11/62

CPC分类号： H01M10/056 ,  C07F7/081 ,  C07F7/12 ,  C07F7/1804 ,  H01G11/58 ,  H01G11/60 ,  H01G11/62 ,  H01M10/0525 ,  H01M10/0569 ,  H01M2300/0002 ,  H01M2300/0028 ,  H01M2300/0034 ,  Y02E60/122 ,  Y02E60/13

摘要： Described herein are liquid, organosilicon compounds that including a substituent that is a cyano (—CN), cyanate (—OCN), isocyanate (—NCO), thiocyanate (—SCN) or isothiocyanate (—NCS). The organosilicon compounds are useful in electrolyte compositions and can be used in any electrochemical device where electrolytes are conventionally used.

公开(公告)号：US20170305939A1

公开(公告)日：2017-10-26

申请号：US15515612

申请日：2015-11-19

申请人： Wacker Chemie AG

发明人： Javad MOHSSENI ,  Jochen GROSS ,  Konrad MAUTNER ,  Natalia SOFINA ,  Till WUESTENFELD

IPC分类号： C07F7/16 ,  B01J8/26

CPC分类号： C07F7/16 ,  B01J8/26 ,  B01J2208/00752 ,  C07F7/12

摘要： Methylchlorosilanes are synthesized by an at least two stage reaction in which contact composition from a first fluidized bed reactor is fed to a second fluidized bed reactor.

公开(公告)号：US20170301953A1

公开(公告)日：2017-10-19

申请号：US15508279

申请日：2015-10-05

申请人： Silatronix, Inc.

发明人： José Adrián Pena Hueso ,  David Osmalov ,  Jian Dong ,  Monica Usrey ,  Michael Pollina ,  Peng Du ,  Liu Zhou ,  Tobias Johnson ,  Deborah Gilbert ,  Robert West

IPC分类号： H01M10/0569 ,  H01M10/0525 ,  H01M4/587 ,  C07F7/18 ,  C07F7/12 ,  H01G11/62 ,  H01G11/60 ,  H01G11/64 ,  H01M4/525

CPC分类号： H01M10/0569 ,  C07F7/081 ,  C07F7/12 ,  C07F7/123 ,  C07F7/126 ,  C07F7/1804 ,  H01G11/60 ,  H01G11/62 ,  H01G11/64 ,  H01M4/525 ,  H01M4/587 ,  H01M10/052 ,  H01M10/0525 ,  H01M2300/0037 ,  Y02E60/13 ,  Y02T10/7011 ,  Y02T10/7022

摘要： Described are compounds of the structure R4—a—Si—(Sp-Y)a—Zb, wherein “a” is integer from 1 to 4; “b” is an integer from 0 to (3×a); “Z,” which is absent when “b”“R” or formula (II), wherein each “R” is halogen, C1-6 linear or branched alkyl, alkenyl, or alkynyl or C1-6 linear or branched halo-alkyl, halo-alkenyl, or halo-alkynyl; each “Sp” C1-15 linear or branched alkylenyl or CMS linear or branched halo-alkylenyl; and each “Y” an organic polar group. Also described are electrolyte compositions containing one or more of these compounds.

公开(公告)号：US09701695B1

公开(公告)日：2017-07-11

申请号：US14985006

申请日：2015-12-30

申请人： American Air Liquide, Inc.

发明人： Glenn Kuchenbeiser ,  Venkateswara R. Pallem ,  Guillaume Husson

IPC分类号： C07F7/02 ,  C07F7/12

CPC分类号： C07F7/025 ,  C07F7/12 ,  C07F7/123

摘要： Disclosed are methods of synthesizing an amino(halo)silane comprising the step of reacting a halosilane having the formula SiaHbXc with an aminosilane having the formula SidHe(NR1R2)f to produce the amino(halo)silane having the formula SiwHxXy(NR1R2)z, wherein X=Br or I; each R1 and R2 is independently selected from a C1-C10 alkyl, aryl, or hetero group; a, d, and w independently=1 to 4; b+c=2a+2; b=1 to 2a+1; c=1 to 2a+1; e+f=2d+2; e=1 to 2d+1; f=1 to 2d+1; x+y+z=2w+2; and R1 and R2 may be joined to form a nitrogen-containing heterocycle.