公开(公告)号：US06200140B1

公开(公告)日：2001-03-13

申请号：US09367189

申请日：1999-08-03

申请人： Douglas Allan Steane

发明人： Douglas Allan Steane

IPC分类号： G09B100

CPC分类号： G09B19/02 ,  G09B23/02

摘要： The teaching aid apparatus provides two balance beams (27, 28), one above the other, on a support post (23). Weight-attachment stations (36) are provided on the left and right arms of both beams, and the stations are marked on the beams with numerals indicative of distance of the station from the beam fulcrum. The beams are connected by means of pinions (32, 34), which constrain the beams to tip in unison in response to unbalance of one beam. The apparatus aids the demonstration of negative concepts to young children.

摘要翻译： 辅助设备在支撑柱（23）上提供两个平衡梁（27,28），一个在另一个上。 重量附着站（36）设置在两个梁的左臂和右臂上，站在标记在梁上，数字表示车站与梁支点的距离。 梁通过小齿轮（32,34）连接，小齿轮（32,34）响应于一个梁的不平衡而一致地约束梁。 该设备有助于向幼儿展示消极概念。

公开(公告)号：US06168439A

公开(公告)日：2001-01-02

申请号：US09383682

申请日：1999-08-26

申请人： Fay Anderson

发明人： Fay Anderson

IPC分类号： G09B100

CPC分类号： A63F3/0423 ,  A63F2011/0067 ,  A63F2250/1068

摘要： A word game for entertaining players and improving their vocabularies. The method of playing the word game comprises the steps of providing a plurality of tiles each with a front and a back. The front and back of each of the tiles has a unique letter of the alphabet imprinted thereon. A timer is provided. The timer expires after a predetermined amount of time has elapsed. A card is provided for each player, each having a plurality of columns and a series of rows. All players simultaneously participate. One player shakes all the tiles in a tumbler and lets one tile fall out. The front and the back of the tile are viewed and the timer is started. Players write two series of words on the card they are holding. Each of the series is written in a unique row of the card. Words in the first series begin with one of the letters of the tile. Words in the second series begin with the other of the letters of the tile. Each of the words written in the first of the columns is of one syllable. Words in consecutive columns increase by one syllable. A score of three points per word per syllable is assigned. The score of all words is summed to obtain a final score. The player having the highest final score is the winner.

摘要翻译： 用于娱乐玩家和改善他们的词汇的单词游戏。 播放单词游戏的方法包括以下步骤：提供多个瓦片，每个瓦片具有前后。 每个瓷砖的正面和背面都有一个印有字母表的独特字母。 提供一个定时器。 定时器在经过预定时间后到期。 为每个玩家提供一张牌，每张牌都有多列和一系列的牌。 所有玩家同时参与。 一个玩家摇动所有的瓷砖在一个滚筒，让一个瓷砖掉落。 查看瓦片的前部和后部，并启动定时器。 玩家在他们持有的卡片上写下两个系列的单词。 每个系列都是写在一张独一无二的卡片上。 第一个系列中的单词以瓦片的一个字母开始。 第二个系列中的单词从瓦片的其他字母开始。 在第一列中写的每个单词都是一个音节。 连续列中的单词增加一个音节。 分配每个音节每个字3分的分数。 所有单词的得分相加得到最终得分。 得分最高的玩家是最高分。

公开(公告)号：US06786729B2

公开(公告)日：2004-09-07

申请号：US10174216

申请日：2002-06-18

申请人： Melinda L. Lee

发明人： Melinda L. Lee

IPC分类号： G09B100

CPC分类号： G09B1/30

摘要： A cognitive matching skill learning aid may include a base having a plurality of different object images thereon and a respective matching block for each object image on the base. The blocks may be movable relative to the base. Moreover, each matching block may have a plurality of sides, and the sides of a given matching block may have different indicia thereon representative of different cognitive matching skill levels with respect to the corresponding object image on the base.

摘要翻译： 认知匹配技能学习辅助可以包括在其上具有多个不同对象图像的基底和在基底上的每个对象图像的相应匹配块。 块可以相对于底座移动。 此外，每个匹配块可以具有多个边，并且给定匹配块的边可以具有不同的标记，其代表相对于基础上的相应对象图像的不同认知匹配技能等级。

公开(公告)号：US06607388B2

公开(公告)日：2003-08-19

申请号：US10126857

申请日：2002-04-18

申请人： Mary Ann Cogliano

发明人： Mary Ann Cogliano

IPC分类号： G09B100

CPC分类号： G09B19/04 ,  G09B5/06

摘要： An educational toy for teaching a child a sequence of letters, numbers, colors or other sequences. The toy would be provided with a plurality of segmented body portions, each of the body portions associated with a single indicia. A switch is provided on each of the segmented body portions. When this switch is depressed, an audio output associated with the indicia would be produced. After the child has memorized a series of indicia to produce a learned sequence, a switch associated with a segmented body portion having demarcation indicia would be depressed, allowing the entire sequence to be vocalized in order.

公开(公告)号：US06669478B2

公开(公告)日：2003-12-30

申请号：US10003517

申请日：2001-11-26

申请人： Ann Edwards ,  Karen Goldberg

发明人： Ann Edwards ,  Karen Goldberg

IPC分类号： G09B100

CPC分类号： G09B5/06 ,  G09B17/006 ,  G09B21/007

摘要： A method and device for teaching the pronunciation of the letters of the alphabet's phonetically correct sound, and recognition of name and shape, for learning reading and writing, utilizing the technique of multi-sensory tactile impressions. Illustrations of letters and their phonetically correct sounds are linked with commonly associated words. For example, the letter “s” is paired with an illustration of and the word “sun” to teach an unvoiced “s” sound; or paired with an illustration of and the word “rose” to teach a voiced “zzz” sound. The letter's textured surface is distinguishable from the pages' flat surface. While simultaneously tracing the letter's bumpy surface, the user vocalizes the letter's name, phonetically correct sound and associated word. Combinations of letters are used to blend sounds to form words. The same method can be used to teach number recognition and meaning.

摘要翻译： 使用多感觉触觉印象的技术，教授字母表的字母正确的声音的发音，以及用于学习阅读和写作的名称和形状的识别的方法和装置。 字母和他们的声音正确的声音插图与常用的关联词相关联。 例如，字母“s”与“太阳”这个词的一个例证配对，以教导一个无声的“声音”; 或与“玫瑰”一词的说明配对，教导一个有声的“zzz”声。 字母的纹理表面可以与页面的平面区分开。 在同时追踪信件颠簸的表面时，使用者发出信件的名字，用声音来纠正声音和相关字词。 字母组合用于混合声音以形成单词。 同样的方法可以用来教授数字识别和意义。

公开(公告)号：US06390821B1

公开(公告)日：2002-05-21

申请号：US09367065

申请日：1999-11-17

申请人： Kevan M. Shokat

发明人： Kevan M. Shokat

IPC分类号： G09B100

CPC分类号： G01N33/5008 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  C07K2319/00 ,  C07K2319/23 ,  C12N9/1205 ,  G01N33/5011 ,  G01N33/502 ,  G01N33/5026 ,  G01N33/5041 ,  G01N33/5091

摘要： Engineered protein kinases which can utilize modified nucleotide triphosphate substrates that are not as readily utilized by the wild-type forms of those enzymes, and methods of making and using them. Modified nucleotide triphosphate substrates and methods of making and using them. Methods for using such engineered kinases and such modified substrates to identify which protein substrates the kinases act upon, to measure the extent of such action, and to determine if test compounds can modulate such action. Also engineered forms of multi-substrate enzymes which covalently attach part or all of at least one (donor) substrate to at least one other (recipient) substrate, which engineered forms will accept modified substrates that are not as readily utilized by the wild-type forms of those enzymes. Methods for making and using such engineered enzymes. Modified substrates and methods of making and using them. Methods for using such engineered enzymes and such modified substrates to identify the recipient substrates the enzymes act upon, to measure the extent of such action, and to measure whether test compounds modulate such action.

摘要翻译： 可以使用不被野生型形式的那些酶所容易利用的修饰的三磷酸核苷酸底物的工程化蛋白激酶，以及制备和使用它们的方法。 修饰的三磷酸核苷底物及其制备和使用方法。 使用这种工程化的激酶和这种修饰的底物以鉴定激酶作用于哪种蛋白质底物的方法，以测量这种作用的程度，以及确定测试化合物是否可以调节这种作用。 同样工程化的多底物酶的形式，其将至少一种（供体）底物的部分或全部共价连接至至少一种其它（受体）底物，其工程化形式将接受改性底物，其不被野生型 这些酶的形式。 制备和使用这些工程化酶的方法。 改性底物及其制备和使用方法。 使用这种工程化酶和这种修饰的底物以鉴定酶作用于受体底物的方法，以测量这种作用的程度，以及测量测试化合物是否调节这种作用。

公开(公告)号：US06293800B1

公开(公告)日：2001-09-25

申请号：US09311504

申请日：1999-05-13

申请人： John Robertson

发明人： John Robertson

IPC分类号： G09B100

CPC分类号： G09B1/00 ,  G09B19/02

摘要： An educational and entertainment device includes n layers stackable in a predetermined order one on top of the other to define a tower having n layers. The xth layer, where x varies between 1 and n, is divided into x sections, at least one of the x sections of the xth layer having a passage segment formed therethrough such that with the n layers stacked one on top of the other in the predetermined order, the passage segments of the n layers are in communication with each other to define a passage which extends through the tower. The device also includes an indicator element passable through the passage to confirm that the n layers have been assembled in the predetermined order.

摘要翻译： 教育和娱乐设备包括可以以预定顺序堆叠的n层，其中一层叠置在另一层之上以限定具有n层的塔。 第x层，其中x在1和n之间变化，被分成x个部分，第x层的x个部分中的至少一个具有穿过其中形成的通道段，使得其中n个层之间堆叠在另一个之上 预定顺序，n层的通道段彼此连通以限定延伸穿过塔的通道。 该装置还包括可通过通道的指示元件，以确认n层已按预定顺序组装。

公开(公告)号：US06739875B1

公开(公告)日：2004-05-25

申请号：US10455401

申请日：2003-06-06

申请人： Fu-Chi Lin

发明人： Fu-Chi Lin

IPC分类号： G09B100

CPC分类号： G09B23/08 ,  G09B19/02

摘要： A teach-aiding weight set includes a white, a red, a light green, a purple, a yellow, a green, a black, a brown, a blue, and an orange weight. Each of the weights is provided with spaced shallow grooves to show a plurality of equal sections corresponding to a specific weight thereof. The specific color, weight, and shallow-groove-divided sections of each of the weights help small children to learn primary mathematical concepts, particularly the concept of weight.

摘要翻译： 教学辅助重量包括白色，红色，浅绿色，紫色，黄色，绿色，黑色，棕色，蓝色和橙色重量。 每个重物设置有间隔开的浅槽，以显示对应于其特定重量的多个相等的部分。 每个重量的具体颜色，重量和浅槽分割部分有助于小孩们学习主要的数学概念，特别是体重的概念。

公开(公告)号：US06716031B2

公开(公告)日：2004-04-06

申请号：US10020570

申请日：2001-12-07

申请人： Michael C. Wood ,  Jorge Garbriel Soto

发明人： Michael C. Wood ,  Jorge Garbriel Soto

IPC分类号： G09B100

CPC分类号： A63H33/00 ,  A63H2200/00

摘要： An interactive learning apparatus is disclosed. In one embodiments, the interactive learning apparatus comprises: (a) a housing; (b) an impact sensor unit in the housing; (c) a processor and memory unit operatively coupled to the impact sensor unit; (d) a display unit operatively coupled to the processor and memory unit; and (e) an audio output unit operatively coupled to the processor and memory unit, wherein the display unit is adapted to display an image in response to the user striking a portion of the housing.

摘要翻译： 公开了一种交互式学习装置。 在一个实施例中，交互式学习装置包括：（a）壳体; （b）壳体中的冲击传感器单元; （c）可操作地耦合到冲击传感器单元的处理器和存储单元; （d）可操作地耦合到所述处理器和存储器单元的显示单元; 和（e）可操作地耦合到所述处理器和存储器单元的音频输出单元，其中所述显示单元适于响应于所述用户触摸所述外壳的一部分而显示图像。

公开(公告)号：US06491524B2

公开(公告)日：2002-12-10

申请号：US09825062

申请日：2001-04-04

申请人： Patricia Bender

发明人： Patricia Bender

IPC分类号： G09B100

CPC分类号： G09B17/003

摘要： A reading device for teaching or learning reading is composed of: (A) a two-layer structure containing a first layer, an opposite second layer, viewing slots formed in corresponding portions of the first and second layers, and a hollow pocket defined between the first and second layers; wherein: the first layer has printed on a front face thereof a letter/image chart, and the second layer has printed on a back face thereof a numerical listing of the names of the objects represented by the images on the letter/image chart; and (B) a flat card having a front face which is blank and a back face which preferably has printed thereon one or more sample words or sentences. The flat card is disposed for insertion into the hollow pocket defined between the first and second layers. Methods for teaching or learning reading using the reading device involves obtaining the reading device; obtaining reading material; and, for each unfamiliar word in the reading material: locating the first letter or single-sound letter combination of the word on the letter/image chart; pronouncing the name of the image proximate to the letter so as to sound out the letter or letter combination; and repeating these two steps for each successive letter or single-sound letter combination in the word so as to pronounce the entire word.

摘要翻译： 用于教学或学习阅读的读取装置由以下部分组成：（A）包含第一层，相对的第二层，形成在第一和第二层的相应部分中的观察槽的两层结构，以及定义在第二层之间的中空袋 第一和第二层; 其中：第一层在其正面上印有字母/图像图，并且第二层在其背面上印有由字母/图像图表上的图像表示的物体的名称的数字列表; 和（B）具有前面是空白的平板卡和优选在其上印刷有一个或多个样本单词或句子的背面。 平卡设置成插入到限定在第一和第二层之间的中空袋中。 使用读取装置进行教学或学习阅读的方法涉及获取读取装置; 获取阅读材料; 并且，对于阅读材料中的每个不熟悉的单词：在字母/图像图表上找到该单词的第一个字母或单个声母组合; 发出靠近信件的图像的名称，以便发出字母或字母的组合; 并对单词中的每个连续的字母或单个声音字母组合重复这两个步骤，以便发音整个单词。