公开(公告)号：US20250057787A1

公开(公告)日：2025-02-20

申请号：US18451071

申请日：2023-08-16

Applicant: KIM DUNG THI DAO

Inventor： KIM DUNG THI DAO ,  BINH CONG DAO ,  TAM CONG NGUYEN ,  VAN BICH NGUYEN ,  BICH LIEN THI NGUYEN ,  THOA THI DAO ,  NHAT VY DAO NGUYEN

IPC: A61K31/12 ,  A61K9/127 ,  A61K31/355 ,  A61K31/519 ,  A61K36/82 ,  A61K36/886 ,  A61K47/24 ,  A61K47/36 ,  A61K47/46

Abstract: A phospholipid composition obtained from the process of forming a homogeneous mixture by mixing (A) a lecithin extract ingredients from egg yolk with (B) a lecithin extract ingredients from plants in a predetermined ratio of (1-3): (1-3); and then adjusting moisture of the homogeneous mixture below 10%. In addition, the invention also discloses the phospholipid composition applied to make the nano liquid product containing curcumin have the ability to treating burns and increasing the effect of scar healing; wherein the product is used at a dose of 0.05-0.1 mL/cm2 of skin, with a frequency of twice daily to reduce the area of the burns, and increasing the concentration of hydroxyproline in the skin.

公开(公告)号：US12214072B2

公开(公告)日：2025-02-04

申请号：US17284984

申请日：2019-11-04

Applicant: AMBROSIA SUPHERB LTD.

Inventor： Sharon Raz

IPC: A61K9/68 ,  A61K9/20 ,  A61K9/28 ,  A61K31/07 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/593 ,  A61K31/714 ,  A61K33/10 ,  A61K33/24 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K36/481 ,  A61K36/484 ,  A61K36/9068

Abstract: The present disclosure provides chewable tablets comprising (i) a compressed core including a bioactive molecule; (ii) a protective layer over said compressed core, and (iii) one or more soft-coating layers over said protective layer, each soft coating layer comprises gum base powder; wherein the protective layer comprises water-insoluble cellulose based polymers, preferably ethyl cellulose based polymer.

公开(公告)号：US12201623B1

公开(公告)日：2025-01-21

申请号：US17839147

申请日：2022-06-13

Applicant: Michael Klipper

Inventor： Michael Klipper

IPC: A61K31/455 ,  A61K9/14 ,  A61K9/16 ,  A61K9/48 ,  A61K31/095 ,  A61K31/315 ,  A61K31/355 ,  A61K31/375 ,  A61K31/51 ,  A61K31/593 ,  A61K36/9066 ,  A61P31/14

Abstract: Disclosed is a pharmaceutical composition in one or more of a solid dosage form, a powder form, a liquid-filled capsule, and a softgel capsule for preventing long-term COVID-19 morbidity. The pharmaceutical composition includes a therapeutically effective amount of a mixture of: nicotinic acid, ascorbic acid, vitamin D, zinc picolinate, selenium, luteolin, methylcobalamin (B12), taurine, turmeric extract (>95% Curcumin), R-alpha-lipoic acid, d1-alpha-tocopheryl acetate (Vitamin E), Co-enzyme Q10 (CoQ10), acetyl-L-carnitine, pyrroloquinoline quinone (PQQ), 5-MTHF methyl folate, lutein, zeaxanthin, thiamine (B1), riboflavin (B2), biotin (B7), pyridoxine hydrochloride (B6), calcium ascorbate, magnesium bisglycinate, copper bisglycinate, panthothenate (B5), betain Hydrochloride, vitamin K2, and boron glycinate.

公开(公告)号：US20250017876A1

公开(公告)日：2025-01-16

申请号：US18884250

申请日：2024-09-13

Applicant: Renibus Therapeutics, Inc.

Inventor： Donald Jeffrey Keyser ,  Alvaro F. Guillem ,  Bhupinder Singh ,  Richard A. Zager

IPC: A61K31/12 ,  A61K9/127 ,  A61K31/145 ,  A61K31/16 ,  A61K31/355 ,  A61K31/375 ,  A61K31/385 ,  A61K31/7048 ,  A61K47/10 ,  A61K47/24 ,  A61K47/34

Abstract: The present invention relates to novel tetrahydrocurcumin (THCu) compositions, novel methods of manufacturing, and methods of using these compositions for therapeutic applications. The novel synthetic pathway(s) result in THCu compositions that generally lack hexahydrocurcumin (HHC), and include an improved impurity profile with reduced additional species that are generally present in hydrogenated curcumin compositions.

公开(公告)号：US12194120B2

公开(公告)日：2025-01-14

申请号：US17890947

申请日：2022-08-18

Applicant: HEIDI SKIN, LLC

Inventor： Heidi Callender ,  Holly Nolan

IPC: A61K8/19 ,  A61K8/64 ,  A61K8/67 ,  A61K8/73 ,  A61K8/9794 ,  A61K9/51 ,  A61K31/355 ,  A61K31/375 ,  A61K31/728 ,  A61K33/38 ,  A61K36/886 ,  A61K36/888 ,  A61K38/06 ,  A61P17/02 ,  A61Q19/00 ,  A61Q19/08

Abstract: The present disclosure provides a skin care formulation, which includes silver nanoparticles (AgNPs) and/or silver microparticles (AgMPs), vitamin E, glycerin, hyaluronic acid or a salt thereof, and water. The skin care formulation may be in a form of a serum. The present formulation may be used for treating a skin condition, such as aging, wrinkle, or pigmentation. The present formulation also may be used for moisturizing, rejuvenating, repairing, or improving aesthetic appearance of a skin of a subject in need thereof.

公开(公告)号：US20250009684A1

公开(公告)日：2025-01-09

申请号：US18893128

申请日：2024-09-23

Applicant: Biogen Extract Private Ltd

Inventor： Mohammed Ali Salman Mehkri

IPC: A61K31/047 ,  A61K31/01 ,  A61K31/015 ,  A61K31/355 ,  A61K36/537 ,  A61K47/36 ,  A61K47/44 ,  A61P27/02

Abstract: Invention deals with a macular carotenoid formulation comprising Carotenoids, Lutein, Zeaxanthin, Meso Zeaxanthin, Beta Carotene, Alpha Carotene, Lycopene and Cryptoxanthin in a synergistic combination. The formulation helps in increasing macular pigment optical density (MPOD) related to prevention of age-related macular degeneration (ARMD). The formulation is used as a nutrient, nutraceutical or dietary supplement. The dietary supplement may be formulated as soft gel capsules, two-piece hard-shell capsules, liquid-fill capsules, tablets, effervescent granules, gummies, powder mixes, stick packs, beverages, emulsions, bakery products, dairy products, tinctures, oil suspensions, beadlets, powders, cold water-soluble powders, emulsions and granules or any combination thereof. The present invention can be used for the development of functional food, dietary plan and as a nutritional supplement. In exemplary embodiment, formulation is available in forms like oil suspension, beadlets, powders, cold water-soluble powders, emulsions and granules.

公开(公告)号：US20250000844A1

公开(公告)日：2025-01-02

申请号：US18756828

申请日：2024-06-27

Applicant: Hill's Pet Nutrition, Inc.

Inventor： Dayakar BADRI ,  Sasha Marie Barnett ,  Kimberly Marie Wilson ,  Jose Bucio ,  Claudia Bentosa

IPC: A61K31/385 ,  A23K20/121 ,  A23K20/158 ,  A23K20/174 ,  A23K50/40 ,  A61K8/34 ,  A61K8/44 ,  A61K8/60 ,  A61K8/9789 ,  A61K31/352 ,  A61K31/355 ,  A61P17/08 ,  A61P17/14 ,  A61Q5/02

Abstract: Pet shampoos, pet food compositions, and methods thereof are disclosed herein. In accordance with an aspect, provided is a method for reducing alopecia, skin secretion, ear secretion, and/or erythema scores of a companion animal comprising: feeding a pet food composition to a pet, and applying a pet shampoo to the pet within about 36 hours of providing the pet food composition to the pet, wherein the pet food composition comprises a plurality of fatty acids selected from omega-3 fatty acids, omega-6 fatty acids, omega-9 fatty acids, and a combination thereof, quercetin, and one or more vitamins comprising a vitamin C, a vitamin E, or a combination thereof; and wherein the pet shampoo comprises: from about 1 to about 15 wt. % of an amphoteric surfactant, from about 5 to about 25 wt. % of a nonionic surfactant, and from about 1 to about 20 wt. % of a polyol.

公开(公告)号：US12168070B2

公开(公告)日：2024-12-17

申请号：US17492386

申请日：2021-10-01

Applicant: Medlab Clinical U.S., Inc.

Inventor： David A. Rutolo, Jr. ,  Sean Michael Hall ,  Luis Vitetta ,  Yusi Zhou ,  Samantha Maree Coulson

IPC: A61K9/00 ,  A61K9/08 ,  A61K9/107 ,  A61K9/70 ,  A61K31/05 ,  A61K31/07 ,  A61K31/122 ,  A61K31/135 ,  A61K31/197 ,  A61K31/355 ,  A61K31/375 ,  A61K31/40 ,  A61K31/4045 ,  A61K31/4188 ,  A61K31/43 ,  A61K31/4415 ,  A61K31/505 ,  A61K31/51 ,  A61K31/525 ,  A61K31/565 ,  A61K31/568 ,  A61K31/57 ,  A61K31/573 ,  A61K31/592 ,  A61K31/593 ,  A61K31/675 ,  A61K31/714 ,  A61K33/00 ,  A61K33/06 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K33/42 ,  A61K36/185 ,  A61K38/05 ,  A61K38/28 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/44

Abstract: Provided herein are transmucosal and transdermal delivery systems comprising: at least one non-ionic surfactant; at least one polyol; and at least one active agent; and optionally further comprising at least one oil. In particular embodiments, the delivery system has an average particle size of from about 5 nm to about 200 nm.

公开(公告)号：US12167997B2

公开(公告)日：2024-12-17

申请号：US18185711

申请日：2023-03-17

Applicant: CytoSolve, Inc.

Inventor： V. A. Shiva Ayyadurai ,  Prabhakar Deonikar

IPC: A61K31/375 ,  A61K31/07 ,  A61K31/353 ,  A61K31/355 ,  A61P39/06

Abstract: The present disclosure is related to dietary supplements. For example, this disclosure relates to compositions that include, one or more agents that decrease the production of reactive oxygen species (ROS) responsible for oxidative stress, and/or decrease the concentration of ROS. In some embodiments, a composition as provided herein includes epicatechin present in an amount of about 0.1% to about 3% w/w of the composition; vitamin A acid present in an amount of about 1% to about 15% w/w of the composition; vitamin C present in an amount of about 10% to about 80% w/w of the composition; and, vitamin E present in an amount of about 5% to about 60% w/w of the composition. Such compositions are useful for improving oxidative stress by decreasing ROS concentration.

公开(公告)号：US12150945B2

公开(公告)日：2024-11-26

申请号：US16517533

申请日：2019-07-19

Applicant: Lipocine Inc.

Inventor： Mahesh V. Patel ,  Nachiappan Chidambaram ,  Satish K. Nachaegari ,  Burke Byrne ,  Kilyoung Kim ,  Jonathan A. Baker

IPC: A61K31/568 ,  A61K31/201 ,  A61K31/355 ,  A61K45/06 ,  A61P1/16 ,  G01N33/92

Abstract: Methods of treating a liver disease or condition, or a symptom thereof, in a subject in need of treatment, are disclosed and described. One method comprises orally administering to a subject, a pharmaceutical composition having an amount of a testosterone, or an ester thereof, sufficient to treat the liver disease or condition, or symptom thereof.