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公开(公告)号:US11881554B2
公开(公告)日:2024-01-23
申请号:US16954836
申请日:2019-07-24
发明人: Daeil Kim , Moon Jeong Park , Jonghyun Chae , Ha Young Jung , Suhwan Kim , Sung Chul Lim , Jihoon Ahn
IPC分类号: H01M10/0565 , C08G65/333 , C08G65/335 , H01M10/0525
CPC分类号: H01M10/0565 , C08G65/3355 , C08G65/33368 , H01M10/0525 , H01M2300/0028 , H01M2300/0065 , H01M2300/0082
摘要: A polymer electrolyte is provided, which includes a polymer including an ethylene oxide unit; and a lithium salt, wherein the terminal of the polymer is substituted with one to four functional groups selected from the group consisting of a nitrogen compound functional group and phosphorus compound functional group, and the terminal of the polymer and the one to four functional groups are linked by one selected from the group consisting of a C2 to C20 alkylene linker, a C2 to C20 ether linker, and a C2 to C20 amine linker. A method for preparing the same is also provided.
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公开(公告)号:US20230285446A1
公开(公告)日:2023-09-14
申请号:US18156058
申请日:2023-01-18
发明人: John C. Alverdy , Matthew Tirrell , Olga Y. Zaborina , Jun Mao , Wei Chen
IPC分类号: A61K31/77 , A61K47/10 , A61K47/34 , A61K31/765 , A61K9/00 , A61K31/80 , A61P31/04 , A61P1/00 , C08G65/335 , C08G81/00
CPC分类号: A61K31/77 , A61K47/10 , A61K47/34 , A61K31/765 , A61K9/0095 , A61K31/80 , A61P31/04 , A61P1/00 , C08G65/3353 , C08G81/00
摘要: The disclosure provides products and methods of treating diseases and disorders involving microbial pathogens, such as intestinal microbial pathogens, e.g., Pseudomonas aeruginosa, by administering an effective amount of a phosphorylated polyethylene glycol compound of defined structural organization. Those diseases and disorders characterized by an epithelium attacked by a microbial pathogen are contemplated, including gastrointestinal infections and inflammation, e.g., treatment of intestinal or esophageal anastomosis or treatment or suppression of anastomotic leakage.
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公开(公告)号:US10442893B2
公开(公告)日:2019-10-15
申请号:US15743139
申请日:2016-07-07
IPC分类号: C08G65/00 , G11B5/00 , C10M107/00 , C08G65/333 , C08G65/335 , G11B5/725 , C10M107/38
摘要: The present invention relates to novel (per)fluoropolyether polymers and their use as lubricants, in particular for Magnetic Recording Media (MRM).
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公开(公告)号:US20190233617A1
公开(公告)日:2019-08-01
申请号:US16339144
申请日:2017-01-31
发明人: Zhang-Lin ZHOU
IPC分类号: C08K5/5397 , C08G65/335 , C08G65/26 , C08F2/50 , C09D11/101 , C09D11/102 , C09D11/54
CPC分类号: C08K5/5397 , C08F2/50 , C08G65/2621 , C08G65/3355 , C09D11/101 , C09D11/102 , C09D11/38 , C09D11/40 , C09D11/54
摘要: The present disclosure is drawn to a polymeric photo active agent which includes diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide modified with a polyether having from 2 to 200 ether groups.
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公开(公告)号:US20190117798A1
公开(公告)日:2019-04-25
申请号:US16229509
申请日:2018-12-21
申请人: ModernaTX, Inc.
发明人: Gilles Besin , Stephen Hoge , Joseph Senn , Kerry Benenato , Staci Sabnis
IPC分类号: A61K48/00 , C12N15/88 , A61K47/10 , A61K47/54 , A61K31/7115 , A61K9/127 , A61K47/69 , A61K47/60 , A61K39/39 , C08G65/332 , C08G65/333 , C08G65/334 , C08G65/335 , C12N15/117 , A61K31/713
摘要: This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.
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公开(公告)号:US10207010B2
公开(公告)日:2019-02-19
申请号:US15674872
申请日:2017-08-11
申请人: ModernaTX, Inc.
发明人: Gilles Besin , Stephen Hoge , Joseph Senn , Kerry Benenato , Staci Sabnis
IPC分类号: C12N15/88 , A61K9/127 , A61K48/00 , A61K47/54 , A61K47/69 , A61K47/60 , A61K31/713 , A61K39/39 , A61K47/10 , C08G65/332 , C08G65/333 , C08G65/334 , C08G65/335 , C12N15/117 , A61K31/7115 , A61K39/00
摘要: This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.
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公开(公告)号:US09975282B2
公开(公告)日:2018-05-22
申请号:US13990426
申请日:2012-01-31
申请人: Satoru Ozawa , Katsuhiro Kojima , Yusuke Nakai
发明人: Satoru Ozawa , Katsuhiro Kojima , Yusuke Nakai
IPC分类号: B29C43/28 , B29C59/04 , C08G65/335 , C08K5/521 , C08K5/00 , C08K5/5397
CPC分类号: B29C43/28 , B29C59/04 , B29C59/046 , C08G65/3353 , C08K5/0025 , C08K5/521 , C08K5/5397
摘要: Described are: an active-energy-ray-curable composition (38) containing a phosphate ester compound of which an aqueous solution prepared by extracting with 50 mL of water per 1 g of the phosphate ester compound has a pH value of 6.5 to 7.5 at 25° C., wherein the value of (the concentration of phosphoric acid in the aqueous solution, expressed in mass ppm)×(the content of the phosphate ester compound in the active-energy-ray-curable composition, expressed in mass %) is 50 or less; and a process for producing a transparent film (40) which includes the active-energy-ray-curable composition (38) and in which a cured resin layer (44) having a fine uneven structure is formed on the surface of a base film (42).
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公开(公告)号:US09926231B2
公开(公告)日:2018-03-27
申请号:US14371096
申请日:2012-12-07
发明人: Joachim Dengler , Alexander Kraus
IPC分类号: C04B24/26 , C04B24/24 , C04B28/02 , C04B28/04 , C04B28/08 , C04B28/14 , C04B28/16 , C08G65/333 , C08G65/335 , C04B103/30 , C04B103/40 , C04B103/52
CPC分类号: C04B24/2611 , C04B24/243 , C04B28/021 , C04B28/04 , C04B28/08 , C04B28/146 , C04B28/147 , C04B28/16 , C04B2103/302 , C04B2103/308 , C04B2103/408 , C04B2103/52 , C08G65/33317 , C08G65/3353 , C08G65/3356 , Y02W30/92 , Y02W30/94 , C04B18/08 , C04B18/141 , C04B2103/0088
摘要: The invention relates to dispersants for inorganic particles, preferably for hydraulic binders, which comprises the following structural units: i) at least one triazine structural unit, ii) at least one polyalkylene glycol structural unit, and iii) at least two phosphoric ester structural units on at least one carbon atom of one or more aromatic triazine rings of the formulae (IIa) and/or (IIb): —N—(CH2CH2—O—PO3H2)2, (IIa) and —NH—CH2CH2—O—PO3H2. (IIb) The invention also relates to a process for preparing the dispersants, to building material mixtures comprising one or more dispersants and one or more inorganic binders. The invention relates to the use of the dispersants as a water reducing agent, as a means for reducing the viscosity and for enhancing the early strengths of aqueous inorganic binders, and also to the use as a grinding aid in the production of cement.
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公开(公告)号:US09745425B2
公开(公告)日:2017-08-29
申请号:US14309042
申请日:2014-06-19
CPC分类号: C08G79/04 , C08G65/3353 , C08K5/524 , C08L23/06 , C08L23/12 , C08L85/02 , C08L2201/08
摘要: A polymeric polyphosphite and copolymeric polyphosphite is described which contains a cycloaliphatic moiety, preferably cyclohexane dimethanol, in the polyphosphite backbone chain. Incorporation of the polymeric polyphosphite into synthetic polymers reduces the yellowness index of any polymer into which the polymeric polyphosphite additive has been added, as well as increased hydrolytic stability as well as increased resistance to migration in food packaging.
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10.
公开(公告)号:US20170189544A1
公开(公告)日:2017-07-06
申请号:US15388227
申请日:2016-12-22
IPC分类号: A61K47/48 , A61K31/23 , A61K31/685 , A61K38/44 , C12N7/00 , C08G65/333 , C08G65/332 , C08G65/335 , A61K9/127 , A61K35/76
CPC分类号: C12N7/00 , A61K9/1271 , A61K31/23 , A61K31/685 , A61K35/76 , A61K38/00 , A61K38/44 , A61K47/60 , A61K47/646 , C08G65/3322 , C08G65/3332 , C08G65/3356 , C12Y107/03003
摘要: Methods are provided for the preparation of conjugates of a variety of bioactive components, especially proteins, with water-soluble polymers (e.g., poly(ethylene glycol) and derivatives thereof), which conjugates have reduced antigenicity and immunogenicity compared to similar conjugates prepared using poly(ethylene glycol) containing a methoxyl or another alkoxyl group. The invention also provides conjugates prepared by such methods, compositions comprising such conjugates, kits containing such conjugates or compositions and methods of use of the conjugates and compositions in diagnostic and therapeutic protocols.
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