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    OSTEOSYNTHESIS WITH NANO-SILVER
    5.
    发明申请
    OSTEOSYNTHESIS WITH NANO-SILVER 审中-公开
    具有纳米银的氧化还原作用

    公开(公告)号：WO2010139451A3

    公开(公告)日：2011-05-26

    申请号：PCT/EP2010003308

    申请日：2010-06-01

    Applicant: AAP BIOMATERIALS GMBH ,  DINGELDEIN ELVIRA ,  GASQUERES CYRILLE ,  WITTE FRANK ,  ELIZIER AMIR

    Inventor： DINGELDEIN ELVIRA ,  GASQUERES CYRILLE ,  WITTE FRANK ,  ELIZIER AMIR

    IPC: A61L27/30 ,  A61L27/54 ,  C23C18/00 ,  C25D11/02

    CPC classification number: C25D11/024 ,  A61L27/306 ,  A61L27/54 ,  A61L31/088 ,  A61L31/16 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/606 ,  A61L2300/802 ,  A61L2400/12 ,  A61L2400/18 ,  A61L2420/06 ,  C25D11/005 ,  C25D11/022

    Abstract: The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO2 coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.

    Abstract translation: 本发明一般涉及一种由银组成的抗菌涂层，医用工具以及包含这种涂层的植入物以及制备这种涂层的方法。 医疗工具或牙科或矫形植入物包括具有处理表面的金属或金属合金，其中经处理的表面至少部分地通过使用胶体分散系统的等离子体电解氧化转化为氧化膜，并且其中转换的表面被部分覆盖 由胶体分散体系的胶体分散的银颗粒形成的岛。 根据本发明的Ag-TiO 2涂层在抗菌功效（甚至针对多抗性菌株），粘附和生物相容性方面表现出优异的性质。 植入物在人体内的寿命增加。 抗菌涂层可用于创伤学，骨科，骨接合术和/或内切除术领域，特别是在存在高感染风险的地方。 目前存在的大量医疗工具和植入物可以受益于这种涂层。

    OSTEOSYNTHESIS WITH NANO-SILVER
    7.
    发明申请
    OSTEOSYNTHESIS WITH NANO-SILVER 审中-公开
    具有纳米银的氧化还原作用

    公开(公告)号：WO2010139451A2

    公开(公告)日：2010-12-09

    申请号：PCT/EP2010/003308

    申请日：2010-06-01

    Applicant: AAP BIOMATERIALS GMBH ,  DINGELDEIN, Elvira ,  GASQUERES, Cyrille ,  WITTE, Frank ,  ELIZIER, Amir

    Inventor： DINGELDEIN, Elvira ,  GASQUERES, Cyrille ,  WITTE, Frank ,  ELIZIER, Amir

    CPC classification number: C25D11/024 ,  A61L27/306 ,  A61L27/54 ,  A61L31/088 ,  A61L31/16 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/606 ,  A61L2300/802 ,  A61L2400/12 ,  A61L2400/18 ,  A61L2420/06 ,  C25D11/005 ,  C25D11/022

    Abstract: The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO 2 coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.

    Abstract translation: 本发明一般涉及一种由银组成的抗菌涂层，医用工具以及包含这种涂层的植入物以及制备这种涂层的方法。 医疗工具或牙科或矫形植入物包括具有处理表面的金属或金属合金，其中经处理的表面至少部分地通过使用胶体分散系统的等离子体电解氧化转化为氧化膜，并且其中转换的表面被部分覆盖 由胶体分散体系的胶体分散的银颗粒形成的岛。 根据本发明的Ag-TiO 2涂层在抗菌功效（甚至针对多抗性菌株），粘附和生物相容性方面表现出优异的性质。 植入物在人体内的寿命增加。 抗菌涂层可用于创伤学，骨科，骨接合术和/或内切除术领域，特别是在存在高感染风险的地方。 目前存在的大量医疗工具和植入物可以受益于这种涂层。

    APATITE COATINGS ON MG SREWS
    9.
    发明申请
    APATITE COATINGS ON MG SREWS 审中-公开
    粉末涂料在MG SREWS上

    公开(公告)号：WO2012007181A1

    公开(公告)日：2012-01-19

    申请号：PCT/EP2011/003582

    申请日：2011-07-18

    Applicant: AAP BIOMATERIALS GMBH ,  DINGELDEIN, Elvira ,  GASQUERES, Cyrille ,  ELIEZER, Amir ,  WOLFSTÄDTER, Marco ,  HEIMANN, Lydia

    Inventor： DINGELDEIN, Elvira ,  GASQUERES, Cyrille ,  ELIEZER, Amir ,  WOLFSTÄDTER, Marco ,  HEIMANN, Lydia

    IPC: A61L31/08 ,  C25D11/30 ,  A61L31/02 ,  A61L31/14

    CPC classification number: A61L31/086 ,  A61L31/022 ,  A61L31/148 ,  A61L2400/18 ,  C25D11/026 ,  C25D11/30

    Abstract: The present invention relates generally to a bio-degradable implant based on magnesium having a reduced corrosion rate and to a method for the production of such an implant. It is a a method for treating a surface of a bio-degradable metallic implant comprising the following steps: providing a dispersed system comprising a colloid-dispersed apatite and adding an apatite powder to the dispersed system, subjecting an implant to the dispersed system such that a surface of the implant which is to be treated is immersed in the dispersed system wherein the implant comprises a magnesium based alloy, applying an AC voltage difference between the implant as a first electrode and a second electrode positioned in the dispersed system for generating a plasma electrolytic oxidation on the immersed surface of the implant so that the immersed surface is converted to an oxide film which is at least partially covered by apatites formed by the colloid-dispersed apatite and the apatite powder. The evolution of corrosion induced hydrogen gas evolution is decreased and osseointegration is improved.

    Abstract translation: 本发明一般涉及具有降低的腐蚀速率的基于镁的生物可降解植入物和用于生产这种植入物的方法。 它是用于处理生物可降解金属植入物的表面的方法，包括以下步骤：提供包含胶体分散的磷灰石并将磷灰石粉末加入到分散体系中的分散体系，使植入物经受分散体系，使得 将待处理的植入物的表面浸入分散体系中，其中植入物包括镁基合金，在作为第一电极的植入物和位于分散系统中的第二电极之间施加AC电压差以产生等离子体电解质 在植入物的浸渍表面上氧化，使得浸入的表面转化为至少部分被由胶体分散的磷灰石和磷灰石粉末形成的磷灰石覆盖的氧化膜。 腐蚀诱导氢气演化的演化减少，骨整体提高。

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