Abstract:
In a chromatography system, including within the system an extraction vessel which receives a mixture of mobile phase and co-solvent and provides a mixture of mobile phase and co-solvent with sample to a chromatography column to increase sample concentration within the mixture. In addition, adding a reservoir to the chromatography system to form an extraction-pressurization system, wherein the mixture with sample may be collected in the reservoir and may diffuse and equilibrate to an approximately uniform sample concentration before being provided to the chromatography column. Also in addition, providing a plurality of extraction-pressurization systems to allow near-simultaneous extraction of sample and loading of the column, or concurrent extraction and loading by the plurality of extraction-pressurization systems.
Abstract:
In a chromatography system, including within the system an extraction vessel which receives a mixture of mobile phase and co-solvent and provides a mixture of mobile phase and co- solvent with sample to a chromatography column to increase sample concentration within the mixture. In addition, adding a reservoir to the chromatography system to form an extraction- pressurization system, wherein the mixture with sample may be collected in the reservoir and may diffuse and equilibrate to an approximately uniform sample concentration before being provided to the chromatography column. Also in addition, providing a plurality of extraction-pressurization systems to allow near-simultaneous extraction of sample and loading of the column, or concurrent extraction and loading by the plurality of extraction- pressurization systems.
Abstract:
본 발명은 영실 추출물을 고수율로 수득하기 위한 방법 및 상기 방법으로 추출된 영실 추출물로부터 활성성분을 검출하는 방법에 관한 것이다. 본 발명에 따른 추출방법을 통해 영실로부터 활성성분이 포함된 영실 추출물을 고수율로 추출할 수 있으며, 상기 추출방법은 영실 추출물을 대량으로 수득할 수 있는 공정이므로 영실 추출물 및 이에 함유된 생리활성 물질의 이용 시 유용하게 이용될 것으로 기대된다.
Abstract:
The present invention relates to a method for detecting or quantifying CTP in a cell sample comprising at least two nucleotide triphosphates by cationic ion pairing chromatography coupled to mass spectrometry, to a method for detecting or quantifying CTP synthase activity based on the method for detecting or quantifying CTP, and to their use in methods for screening potential immunosuppressive or anti-cancer compounds and in methods for determining the appropriate dose of an immunosuppressive or anti-cancer compound inhibiting CTP synthase activity for a treated subject.