公开(公告)号：WO2015051062A1

公开(公告)日：2015-04-09

申请号：PCT/US2014/058731

申请日：2014-10-02

Applicant: BLOXR CORPORATION

Inventor： KHANDKAR, Ashok C. ,  CHOWDHARY, Prataprai

IPC: C09D7/12 ,  C09D201/00

CPC classification number: C09D5/32 ,  C08K2003/221 ,  C08K2003/3045

Abstract: A coating is provided that attenuates ionizing radiation. The coating may include a binder and a component that attenuates ionizing radiation. The ionizing radiation attenuating component of the coating may comprise a radio-opaque material. The radio-opaque material may be non-toxic and/or non-hazardous.

Abstract translation: 提供衰减电离辐射的涂层。 涂层可以包括粘合剂和减弱电离辐射的组分。 涂层的电离辐射衰减部件可以包括不透射线的材料。 不透射线的材料可能是无毒的和/或非危险的。

公开(公告)号：WO2015031252A1

公开(公告)日：2015-03-05

申请号：PCT/US2014/052520

申请日：2014-08-25

Applicant: MERIT MEDICAL SYSTEMS, INC.

Inventor： MOTTOLA, Jim ,  CARLSTROM, Stephen W. ,  RAMRAKHA, Punit Satyavrat ,  SHIRLEY, Nate

IPC: A61M29/00 ,  A61M25/09 ,  A61B17/34 ,  A61M39/02 ,  A61M39/20

CPC classification number: A61M29/00 ,  A61M2025/0018 ,  A61M2025/0076 ,  A61M2025/0183 ,  A61M2210/12

Abstract: Dilators, such as rapid exchange dilators, configured for percutaneous access are disclosed. The dilator may be configured to be disposable within, or couplable with, a catheter. In some embodiments, the dilator, or the coupled dilator and the catheter, may be configured such that a sheath is not required for percutaneous access. In other embodiments, the dilator may comprise a plug such that a guide wire may be directed from a distal end of the dilator through a port, such as a rapid exchange port, in a sidewall of the dilator. The plug may also be configured to permit passage of fluid through a lumen of the dilator while inhibiting passage of the guide wire through a length of the dilator.

Abstract translation: 公开了配置用于经皮进入的扩张器，例如快速置换扩张器。 扩张器可以构造成在导管内是可弃置的，或者可以与导管联接。 在一些实施例中，扩张器或耦合的扩张器和导管可以被配置为使得护套不需要用于经皮进入。 在其他实施例中，扩张器可以包括插头，使得导丝可以从扩张器的远端通过扩张器的侧壁中的端口（例如快速交换端口）引导。 塞子还可以被配置为允许流体通过扩张器的内腔，同时阻止导丝通过一段长度的扩张器。

公开(公告)号：WO2015013622A1

公开(公告)日：2015-01-29

申请号：PCT/US2014/048204

申请日：2014-07-25

Applicant: MERIT MEDICAL SYSTEMS, INC.

Inventor： HOPKINSON, Aaron J. ,  GOLDSTON, Hugh W.

IPC: A61M25/10 ,  A61M25/01 ,  A61M29/02

CPC classification number: A61M25/10 ,  A61M25/002 ,  A61M25/0032 ,  A61M25/005 ,  A61M25/0052 ,  A61M25/0097 ,  A61M25/09041 ,  A61M25/1006 ,  A61M2025/0059 ,  A61M2025/0063 ,  A61M2025/0177 ,  A61M2025/1056 ,  A61M2025/1061

Abstract: The embodiments disclosed herein relate to balloon catheter assemblies. The balloon catheter assemblies can include a hub, an elongated member, and an inflation balloon. The balloon catheter assemblies can also include a support wire having a proximal end that is longitudinally displaceable within a sleeve that is disposed in the catheter hub. A distal end of the support wire may be coupled to the inflation balloon at one or more positions.

Abstract translation: 本文公开的实施例涉及气囊导管组件。 气囊导管组件可以包括轮毂，细长构件和充气气囊。 气囊导管组件还可以包括支撑线，所述支撑线具有在设置在导管座中的套筒内纵向移位的近端。 支撑线的远端可以在一个或多个位置处联接到充气气球。

公开(公告)号：WO2014194216A1

公开(公告)日：2014-12-04

申请号：PCT/US2014/040269

申请日：2014-05-30

Applicant: MERIT MEDICAL SYSTEMS, INC. ,  INTERMOUNTAIN INVENTION MANAGEMENT, LLC

Inventor： BUNCH, T. Jared ,  ORR, Troy Jesse ,  STEVENS, Brian

IPC: A61M25/14 ,  A61M25/02 ,  A61M5/32

CPC classification number: A61M25/0097 ,  A61B2017/3411 ,  A61M25/01 ,  A61M25/0606 ,  A61M2210/12

Abstract: Various medical procedures benefit from the creation of multiple access sites in a single anatomical vessel. For example, in some cardiac procedures, a plurality of catheters may be introduced into a single blood vessel through a corresponding plurality of access sites. The present application discloses devices for creating multiple access sites in a vessel and methods of using the same.

Abstract translation: 在单个解剖血管中创建多个进入位点，各种医疗手术受益匪浅。 例如，在一些心脏手术中，多个导管可以通过相应的多个接入部位被引入单个血管。 本申请公开了用于在船舶中创建多个接入站点的设备及其使用方法。

公开(公告)号：WO2014159710A1

公开(公告)日：2014-10-02

申请号：PCT/US2014/024868

申请日：2014-03-12

Applicant: MERIT MEDICAL SYSTEMS, INC.

Inventor： MOWER, Wayne L. ,  HALL, John William ,  SIMMONS, Rachel L. ,  DOLMATCH, Bart ,  FERGUSON, F. Mark

IPC: D04H3/005 ,  D01F6/28

CPC classification number: A61L27/50 ,  A61L27/16 ,  A61L29/041 ,  A61L29/146 ,  A61L31/048 ,  A61L31/14 ,  B29C55/04 ,  B29K2027/18 ,  D01D5/0007 ,  D01D5/0076 ,  D01D5/18 ,  D01F6/12 ,  F16L11/11 ,  F16L11/115 ,  Y10T442/60 ,  Y10T442/626 ,  Y10T442/643 ,  C08L27/18

Abstract: Fibrous materials and methods of manufacturing fibrous materials are disclosed. In particular, this application discloses methods of making and processing serially deposited fibrous structures, such as serially deposited fibrous mats. Serially deposited fibrous mats may be used in implantable medical devices with various characteristics and features. Serially deposited fibrous mats of various mat thickness, fiber size, porosity, pore size, and fiber density are disclosed. Additionally, serially deposited fibrous mats having various amounts of fiber structures (such as intersections, branches, and bundles) per unit area are also disclosed.

Abstract translation: 公开了纤维材料和纤维材料的制造方法。 特别地，本申请公开了制备和加工串联沉积的纤维结构体的方法，例如串联沉积的纤维垫。 系列沉积的纤维垫可用于具有各种特征和特征的可植入医疗装置中。 公开了具有各种垫厚度，纤维尺寸，孔隙率，孔径和纤维密度的系列沉积纤维垫。 此外，还公开了每单位面积具有各种数量的纤维结构（例如交叉点，分支和束）的串联沉积的纤维垫。

公开(公告)号：WO2014159399A1

公开(公告)日：2014-10-02

申请号：PCT/US2014/023416

申请日：2014-03-11

Applicant: MERIT MEDICAL SYSTEMS, INC.

Inventor： HALL, John William ,  BOYD, Randal ,  NEYME, Dylan ,  FERGUSON, F. Mark

IPC: A61F2/82 ,  A61F2/86

CPC classification number: B29C47/0014 ,  A61F2/82 ,  A61F2/86 ,  A61F2240/001 ,  B29C47/026 ,  D01D5/0076 ,  D01D5/18 ,  D01D7/00

Abstract: The present disclosure relates to methods and systems for manufacturing rotational spun materials. The rotational spun materials are medical appliances or other prostheses made of, constructed from, covered or coated with rotational spun materials, such as polytetrafluoroethylene (PTFE).

Abstract translation: 本公开涉及用于制造旋转纺丝材料的方法和系统。 旋转纺丝材料是由旋涂纺丝材料如聚四氟乙烯（PTFE）制成，覆盖或涂覆的医疗器具或其他假体。

公开(公告)号：WO2014143676A1

公开(公告)日：2014-09-18

申请号：PCT/US2014/027737

申请日：2014-03-14

Applicant: THE UNIVERSITY OF UTAH RESEARCH FOUNDATION

Inventor： KORENBERG, Julie Ruth ,  WILCOX, Karen Sue ,  WEST, Peter Jeffrey ,  KESNER, Raymond Pierre

IPC: A01N43/58 ,  A01N43/60

CPC classification number: A61K31/505 ,  A61K31/404 ,  A61K31/4045 ,  A61K31/454 ,  A61K31/4745 ,  A61K31/495 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/506 ,  A61K45/06 ,  C07D209/14 ,  C07D239/50 ,  C07D295/096 ,  C07D401/04 ,  C07D401/10 ,  C07D487/04

Abstract: Methods for treating Down syndrome and improving cognitive function of a patient with an intellectual disability are disclosed. 5-hydroxytryptamine sub-receptor six (5-HT 6 ) receptor antagonists are provided for improving the cognition of a Down syndrome patient.

Abstract translation: 公开了治疗唐氏综合症和提高智力障碍患者认知功能的方法。 提供5-羟色胺亚受体六（5-HT6）受体拮抗剂用于改善唐氏综合症患者的认知。

公开(公告)号：WO2014138404A1

公开(公告)日：2014-09-12

申请号：PCT/US2014/021220

申请日：2014-03-06

Applicant: MERIT MEDICAL SYSTEMS, INC.

Inventor： HALL, John, William

IPC: A61F2/01 ,  A61B17/22 ,  A61M25/10

CPC classification number: A61M25/104 ,  A61F2/013 ,  A61F2230/0006 ,  A61F2230/0039 ,  A61F2230/0069 ,  A61F2230/0076 ,  A61F2250/0003 ,  A61F2250/0084 ,  A61M25/1002 ,  A61M2025/1054 ,  A61M2025/1059 ,  A61M2025/1072 ,  A61M2025/1075 ,  A61M2025/1097

Abstract: An embolic filter balloon is disclosed. The embolic filter balloon may comprise an inflatable balloon portion. Further, the inflatable balloon portion may be coupled to a filter member. The embolic filter balloon may be disposed in a body lumen. In some embodiments, the embolic filter balloon may be configured such that when the inflatable balloon portion is at least partially inflated the filter member extends at least partially across the body lumen. Such a configuration may allow the embolic filter balloon, when deployed, to filter particles greater than a predetermined size from a fluid in the body lumen.

Abstract translation: 公开了栓塞过滤器气囊。 栓塞过滤器气囊可以包括可膨胀气囊部分。 此外，可膨胀气囊部分可以联接到过滤构件。 栓塞过滤器球囊可以设置在体腔中。 在一些实施例中，栓塞过滤器球囊可以被配置为使得当可膨胀气囊部分至少部分地膨胀时，过滤构件至少部分延伸穿过体腔。 这种构造可以允许栓塞过滤器气囊在展开时从体腔中的流体过滤大于预定尺寸的颗粒。

公开(公告)号：WO2014113589A1

公开(公告)日：2014-07-24

申请号：PCT/US2014/011891

申请日：2014-01-16

Applicant: MERIT MEDICAL SYSTEMS, INC.

Inventor： LAMPROPOULOS, Fred ,  MCARTHUR, Gregory R.

IPC: A61B19/00 ,  A61B17/12 ,  B02C18/06

CPC classification number: B02C18/182 ,  A61B17/12109 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00526 ,  B02C18/142 ,  B02C18/24 ,  B26D1/18 ,  Y10T83/869 ,  Y10T83/8821

Abstract: Apparatuses for grinding or cutting surgical foam are disclosed herein. Kits for grinding or cutting surgical foam are disclosed herein. Methods of grinding surgical foam with a plurality of teeth are disclosed herein. Methods of cutting surgical foam are disclosed herein. Methods of embolizing with ground or cut surgical foam are disclosed herein.

Abstract translation: 本文公开了用于研磨或切割手术泡沫的装置。 本文公开了用于研磨或切割手术泡沫的组件。 本文公开了具有多个齿的手术泡沫的研磨方法。 本文公开了切割手术泡沫的方法。 本文公开了用研磨或切割的手术泡沫栓塞栓塞的方法。

公开(公告)号：WO2014014769A1

公开(公告)日：2014-01-23

申请号：PCT/US2013/050254

申请日：2013-07-12

Applicant: MERIT MEDICAL SYSTEMS, INC.

Inventor： ASH, Stephen, R.

IPC: A61M5/00 ,  A61M5/14

CPC classification number: A61M25/0043 ,  A61M1/3661 ,  A61M25/003 ,  A61M25/0032 ,  A61M25/04 ,  A61M2025/0031 ,  A61M2025/0034 ,  A61M2025/0037

Abstract: Disclosed herein are various embodiments of catheters configured to reduce, minimize or prevent occlusion of blood flow resulting from thrombus or fibrin sheath formation, related systems, and methods of use.

Abstract translation: 本文公开了导管的各种实施例，其被配置为减少，最小化或防止由血栓或纤维蛋白鞘形成引起的血流阻塞，相关系统和使用方法。