PHOTOMETRIC APPARATUS AND METHOD FOR MEASURING HEMOGLOBIN
    101.
    发明申请
    PHOTOMETRIC APPARATUS AND METHOD FOR MEASURING HEMOGLOBIN 审中-公开
    光学仪器和测量HEMOGLOBIN的方法

    公开(公告)号:WO1991005254A1

    公开(公告)日:1991-04-18

    申请号:PCT/US1990005370

    申请日:1990-09-20

    申请人: ARTEL

    IPC分类号: G01N33/49

    摘要: An apparatus and method for making a photometric absorbance measurement of hemoglobin in a blood sample utilizing a reusable cuvette (10) and an inexpensive photometer. The cuvette (10) is a unitary plastic body having a flow-through slot (15) of a predetermined height which allows an absorbance measurement to be made with an undiluted blood sample and which permits cleaning by inserting the body in a liquid cleaning solution. Two absorbance measurements are made, the first at a wavelength at which the absorbance of oxyhemoglobin and deoxyhemoglobin are approximately equal, near an isobestic point, and a second measurement at which these components absorb substantially no light. By making the first measurement near an absorbance minimum at about 510 nm, an absorbance measurement can be made with a relatively thick slot.

    DIFFERENTIAL REFRACTOMETER
    104.
    发明申请
    DIFFERENTIAL REFRACTOMETER 审中-公开
    差分压力计

    公开(公告)号:WO1990004165A1

    公开(公告)日:1990-04-19

    申请号:PCT/US1989002255

    申请日:1989-05-25

    IPC分类号: G01N21/41

    摘要: This invention measures the change of a fluid's refractive index with changes in the concentration of a solute dissolved therein. A determination of this quantity is required for many types of chemical analyses especially for the determination of molecular weights. The fluid is restricted to a thin capillary channel (11) within a transparent material (10) such as glass. A fine light beam (18) is incident upon the capillary at an angle close to the critical angle. The axes of the light beam and capillary intersect at a point within the capillary defining thereby a plane within which the refraction occurs. A position sensing (27) device is placed to measure the displacement of the beam twice refracted during its passage through the capillary channel, said measure being used to generate a numerical value of the ratio dn/dc, where dc is the change of solute concentration resulting in a change dn of the solution's refractive index.

    摘要翻译: 本发明通过溶解在其中的溶质浓度的变化来测量流体的折射率的变化。 对于许多类型的化学分析,特别是用于测定分子量,需要确定该量。 流体被限制在诸如玻璃的透明材料(10)内的细毛细通道(11)上。 细光束(18)以接近临界角的角度入射到毛细管上。 光束和毛细管的轴线在毛细管内的点处相交,从而形成出现折射的平面。 放置位置检测(27)装置以测量在其通过毛细管通道期间两次折射的光束的位移,所述测量用于产生比值dn / dc的数值,其中dc是溶质浓度的变化 导致溶液折射率的变化dn。

    METHOD AND DEVICE FOR CHEMILUMINESCENCE-BASED ANALYSIS
    105.
    发明申请
    METHOD AND DEVICE FOR CHEMILUMINESCENCE-BASED ANALYSIS 审中-公开
    用于基于化学发光的分析的方法和装置

    公开(公告)号:WO2017221258A1

    公开(公告)日:2017-12-28

    申请号:PCT/IL2017/050701

    申请日:2017-06-25

    IPC分类号: G01N21/76 B01L3/00

    摘要: A method for detecting an analyte reactive towards luminol, comprising the steps of: feeding into a reaction chamber an alkaline solution of luminol, noble metal nanoparticles and at least one analyte reactive towards luminol, wherein the reaction chamber is in the form of a curved channel; detecting the light emitted due to a chemiluminescence reaction taking place in said channel; and discharging a reaction mass from said channel, characterized in that the average diameter of the metal nanoparticles is greater than 25nm. Also provided is a microfluidic device for carrying out the method.

    摘要翻译: 一种用于检测对鲁米诺具有反应性的分析物的方法,包括以下步骤:将鲁米诺碱性溶液,贵金属纳米颗粒和至少一种对鲁米诺呈反应性的分析物进料到反应室中,其中所述反应室 是弯曲通道的形式; 检测由于在所述通道中发生的化学发光反应而发射的光; 以及从所述通道中排出反应物质,其特征在于,所述金属纳米颗粒的平均直径大于25nm。 还提供了用于执行该方法的微流体装置。

    POROUS MESH SPECTROMETRY METHODS AND APPARATUS
    106.
    发明申请
    POROUS MESH SPECTROMETRY METHODS AND APPARATUS 审中-公开
    多孔网格光谱测定方法和装置

    公开(公告)号:WO2017165403A1

    公开(公告)日:2017-09-28

    申请号:PCT/US2017/023389

    申请日:2017-03-21

    申请人: NUEON INC.

    摘要: Described herein are methods and apparatus for spectroscopic analysis of samples. In many embodiments, an apparatus for providing spectroscopic analysis of a sample comprises a sample holder. For example, the sample holder may comprise a consumable single use sample holder that can be readily coupled to and removed from a measurement apparatus such as a spectrometer. The sample holder may comprise a measurement surface configured to receive the sample during measurement, wherein the measurement surface may comprise a porous mesh. The porous mesh can receive the sample to optimally configure the sample for spectroscopic measurement, as described in further detail herein.

    摘要翻译: 这里描述的是用于样品的光谱分析的方法和设备。 在许多实施例中,用于提供样本的光谱分析的设备包括样本架。 例如,样本保持器可以包括可容易地耦合到测量装置(例如分光计)并从测量装置移除的可消耗单次使用样本保持器。 样本保持器可以包括构造成在测量期间接收样本的测量表面,其中测量表面可以包括多孔网。 如本文进一步详细描述的,多孔网可以接收样本以最佳地配置用于光谱测量的样本。

    WAVEGUIDE-BASED DETECTION SYSTEM WITH SCANNING LIGHT SOURCE
    107.
    发明申请
    WAVEGUIDE-BASED DETECTION SYSTEM WITH SCANNING LIGHT SOURCE 审中-公开
    基于波导的检测系统,具有扫描光源

    公开(公告)号:WO2017059425A1

    公开(公告)日:2017-04-06

    申请号:PCT/US2016/055167

    申请日:2016-10-03

    申请人: LDIP, LLC

    摘要: The invention provides methods and devices for generating optical pulses in one or more waveguides using a spatially scanning light source. A detection system, methods of use thereof and kits for detecting a biologically active analyte molecule are also provided. The system includes a scanning light source, a substrate comprising a plurality of waveguides and a plurality of optical sensing sites in optical communication with one or more waveguide of the substrate, a detector that is coupled to and in optical communication with the substrate, and means for spatially translating a light beam emitted from said scanning light source such that the light beam is coupled to and in optical communication with the waveguides of the substrate at some point along its scanning path. The use of a scanning light source al lows the coupling of light into the waveguides of the substrate in a simple and cost-effective manner.

    摘要翻译: 本发明提供了使用空间扫描光源在一个或多个波导中产生光脉冲的方法和装置。 还提供了检测系统,其使用方法和用于检测生物活性分析物分子的试剂盒。 该系统包括扫描光源,包括多个波导的基板和与基板的一个或多个波导光学通信的多个光学感测位置,耦合到基板并与光学连接的检测器,以及装置 用于空间地平移从所述扫描光源发射的光束,使得所述光束在沿其扫描路径的某点处耦合到所述衬底的波导并与所述衬底的波导光通信。 扫描光源的使用降低了以简单且成本有效的方式将光耦合到衬底的波导中。

    成分測定装置及び測定用チップ
    109.
    发明申请
    成分測定装置及び測定用チップ 审中-公开
    组件测量设备和测量芯片

    公开(公告)号:WO2016051930A1

    公开(公告)日:2016-04-07

    申请号:PCT/JP2015/070538

    申请日:2015-07-17

    发明人: 滝浪雅夫

    摘要:  血糖計(10)(成分測定装置)は、測定用チップ(12)と、挿入孔(58)を有する装置本体(16)とを含む。測定用チップ(12)は、一対の板片(30)と、一対の板片(30)の間に配置されるスペーサ(32)と、血液を保持可能な空洞部(20)とを有する。測定部(14)及び該測定部(14)付近で対向し合う挿入孔(58)の一対の壁部(62)は、測定用チップ(12)の積層方向の厚みよりも小さい幅で離間している。スペーサ(32)は、一対の壁部(62)に一対の板片(30)が押圧されることで弾性変形し、空洞部(20)の幅を規定する。

    摘要翻译: 该血糖仪(10)(部件测量装置)包括测量芯片(12)和具有插入开口(58)的装置底盘(16)。 测量芯片(12)具有一对板片(30),布置在一对板片(30)之间的间隔物(32)和能够保持血液的空腔(20)。 测量单元(14)和在测量单元(14)附近彼此面对的插入开口(58)的一对壁部分(62)间隔开宽度小于测量芯片(12)的厚度 )。 间隔件32通过一对壁部62压入一对板片30而发生弹性变形,从而调节空腔20的宽度。

    反応方法、検出方法および検出装置
    110.
    发明申请
    反応方法、検出方法および検出装置 审中-公开
    反应方法,检测方法和检测装置

    公开(公告)号:WO2016031412A1

    公开(公告)日:2016-03-03

    申请号:PCT/JP2015/070150

    申请日:2015-07-14

    发明人: 村山 貴紀

    摘要:  第1の工程では、液体を収容するための収容部内においてブロッキング剤を含むブロッキング液を移動させて、前記収容部内をブロッキング処理する。第2の工程では、前記収容部内に被反応物質(被検出物質)を含む液体を提供して、前記収容部に露出し、かつ捕捉体が固定されている反応場に前記被反応物質を捕捉させる。前記第2の工程は、前記第1の工程の次に行われるか、または前記第1の工程と同時に行われる。

    摘要翻译: 在第一步骤中,将含有封闭剂的封闭溶液移动通过用于容纳液体的容纳部分,从而使所述容纳部分的内部进行封闭处理。 在第二步骤中,将含有被反应的物质(被检测物质)的液体供给到容纳部的内部,暴露于容纳部,并捕获在捕获体被固定的反应部位。 第二步是在第一步之后或第一步同步进行。