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    A HANDHELD AND PORTABLE MICROFLUIDIC DEVICE TO AUTOMATICALLY PREPARE NUCLEIC ACIDS FOR ANALYSIS
    31.
    发明申请
    A HANDHELD AND PORTABLE MICROFLUIDIC DEVICE TO AUTOMATICALLY PREPARE NUCLEIC ACIDS FOR ANALYSIS 审中-公开
    手持式和便携式微流控装置自动制备核酸进行分析

    公开(公告)号：WO2006029387A1

    公开(公告)日：2006-03-16

    申请号：PCT/US2005/032359

    申请日：2005-09-09

    申请人： MICROFLUIDIC SYSTEMS INC. ,  YUAN, Bob ,  AFLATOONI, Nima

    发明人： YUAN, Bob ,  AFLATOONI, Nima

    IPC分类号： B01L3/02

    CPC分类号： G01N1/40 ,  B01L3/0217 ,  B01L3/0293 ,  B01L3/502 ,  B01L3/5027 ,  B01L9/527 ,  B01L2300/0681 ,  B01L2400/0478 ,  B01L2400/0487 ,  G01N1/14 ,  G01N1/405

    摘要： A handheld and portalbe extraction device (10) is directed to a microfluidic-based system to be used in the field to extract and purify an analyte, preferably a nucleic acid, from a fluid-based sample. Preferably, the fluid-based sample is water-based. The fluid-based sample can also be a biological fluid sample. The handheld and portable extraction device includes a syringe-like device (14) coupled to a purification chip (48). The purification chip is preferably included within a chip block (40), which is removable from the remaining portion of the handheld and portable extraction device. The analyte collected within the purification chip can be later removed and collected for analysis.

    摘要翻译： 手持式和门式提取装置（10）被引导到在本领域中使用的基于微流体的系统，以从基于流体的样品中提取和纯化分析物，优选核酸。 优选地，基于流体的样品是水基的。 基于流体的样品也可以是生物流体样品。 手持和便携式提取装置包括联接到净化芯片（48）的注射器状装置（14）。 净化芯片优选地包括在可从手持式和便携式提取装置的其余部分移除的芯片块（40）内。 收集在净化芯片内的分析物可以随后被去除并收集用于分析。

    A METHOD AND APPARATUS FOR OBTAINING A MICRO-SAMPLER DOWNHOLE
    36.
    发明申请
    A METHOD AND APPARATUS FOR OBTAINING A MICRO-SAMPLER DOWNHOLE 审中-公开
    一种用于获取微型采样器下水道的方法和装置

    公开(公告)号：WO2004099564A2

    公开(公告)日：2004-11-18

    申请号：PCT/US2004/013552

    申请日：2004-05-03

    申请人： BAKER HUGHES INCORPORATED

    发明人： SHAMMAI, Houman, M. ,  GORDON, Robert ,  SANCHEZ, Frank

    IPC分类号： E21B49/00

    CPC分类号： G01V8/02 ,  E21B49/081 ,  G01N1/14 ,  G01N21/31 ,  G01N21/65 ,  G01N33/2823 ,  G01N2021/651

    摘要： The present invention provides a downhole sample tank and a plurality of micro sample chambers. The micro sample chambers can have at least one window for introduction of visible, near-infrared (NIR), mid-infrared (MIR) and other electromagnetic energy into the tank for samples collected in the micro sample chamber downhole from an earth boring or well bore. The window is made of sapphire or another material capable of allowing electromagnetic energy to pass through the window. The entire micro sample chamber can be made of sapphire or another material capable of allowing electromagnetic energy to pass another material enabling visual inspection or analysis of the sample inside the micro sample chamber. The micro sample chamber enables immediate testing of the sample on location at the surface to determine the quality of the sample in the main sample tank or to enable comprehensive testing of the sample.

    摘要翻译： 本发明提供一种井下样品池和多个微量样品室。 微型样品室可以具有至少一个窗口，用于将可见光，近红外（NIR），中红外（MIR）和其他电磁能引入到从钻孔或井的井下收集的样品室中的样品的槽中 孔。 窗户由蓝宝石或能够允许电磁能量通过窗户的其他材料制成。 整个微量样品室可以由蓝宝石或能够允许电磁能通过另一种材料的材料制成，从而能够对微量样品室内的样品进行目视检查或分析。 微量样品室能够立即对样品在表面的位置进行测试，以确定样品在主样品箱中的质量，或者可以对样品进行全面测试。

    DEVICE FOR AUTOMATIC AND PROGRAMMED SAMPLING AND DOSINGOF LIQUID MEDIUMS
    37.
    发明申请
    DEVICE FOR AUTOMATIC AND PROGRAMMED SAMPLING AND DOSINGOF LIQUID MEDIUMS 审中-公开
    用于自动和编程采样和液体液体的设备

    公开(公告)号：WO2004081540A2

    公开(公告)日：2004-09-23

    申请号：PCT/HR2003/000032

    申请日：2003-06-20

    申请人： VUKOMANOVIC, Stevan

    发明人： VUKOMANOVIC, Stevan

    IPC分类号： G01N1/14

    CPC分类号： G01N1/14 ,  G01N2001/1093 ,  G01N2001/205 ,  G01N2001/2071

    摘要： The design of the device allows automatic and programmed liquid medium sampling during a technological process. A sample obtained by periodical withdrawing is highly representative and used in laboratory analysis ofi product quality control. The device consists of a housing accommodating the pistons (3) and (4) the movement of which works on the pin (9) to close the opening of the seat (11) and let the medium from the chamber (14) flow out into the vessel (12). The spring (8) returns the pistons (3) and (4) into the upper position and the chamber (14) is filled with the medium. The spring (10) works on the pin (9) to close the opening of the seat (11). During the sampling, the withdrawn medium is stored in the vessel (12) which is detachable, sealed tight and safiely carried away to the laboratory. Since the devices of this type are mostly used in oil and petrochemical industry, they are explosion-proof. The invention can also be used for dosing liquid mediums into the technological process.

    摘要翻译： 该设备的设计允许在工艺过程中进行自动和程序化的液体介质取样。 通过定期取款获得的样品是高度代表性的，用于产品质量控制的实验室分析。 该装置包括容纳活塞（3）和（4）的壳体，其运动在销（9）上工作以封闭座（11）的开口，并使来自室（14）的介质流出 容器（12）。 弹簧（8）将活塞（3）和（4）返回到上部位置，并且腔室（14）被填充介质。 弹簧（10）在销（9）上工作以封闭座椅（11）的开口。 在取样期间，取出的介质储存在容器（12）中，容器（12）可拆卸，密封并密封地携带到实验室。 由于这种装置主要用于石油和石化行业，因此具有防爆功能。 本发明还可以用于将液体介质给予技术过程。

    APPARATUS AND METHOD FOR COLLECTING SOIL SOLUTION SAMPLES
    38.
    发明申请
    APPARATUS AND METHOD FOR COLLECTING SOIL SOLUTION SAMPLES 审中-公开
    用于收集土壤溶液样品的装置和方法

    公开(公告)号：WO2004071162A2

    公开(公告)日：2004-08-26

    申请号：PCT/IL2004/000130

    申请日：2004-02-10

    申请人： KADMAN, Yoram ,  SHILONI, Amnon

    发明人： KADMAN, Yoram ,  SHILONI, Amnon

    IPC分类号： A01C

    CPC分类号： G01N1/14 ,  E02D1/06 ,  G01N1/16 ,  G01N2001/1093 ,  G01N2033/245

    摘要： A system for collecting soil solution samples including a sampling device arranged to contact soil and coupled to a vacuum source, and a suction unit for automatically controlling pressure and time of operation of the vacuum source to provide suction for withdrawing solution from the soil through the sampling device and abrupt release of the vacuum at the end of a pre-defined sampling period, and a method for collecting soil solution samples including coupling a sampling device to a vacuum source, planting the sampling device in soil to be monitored, automatically controlling pressure and time of operation of the vacuum source to provide suction for withdrawing solution from the soil through said sampling device, and automatically stopping the vacuum source and abruptly releasing the vacuum at the end of a pre-defined sampling period.

    摘要翻译： 一种用于收集土壤溶液样品的系统，包括布置成接触土壤并且耦合到真空源的取样装置，以及用于自动控制真空源的压力和操作时间的抽吸单元，以通过采样提供抽吸以从土壤中抽出溶液 装置和在预定义的采样周期结束时真空的突然释放，以及收集土壤溶液样品的方法，包括将取样装置耦合到真空源，将取样装置种植在待监测的土壤中，自动控制压力和 真空源的操作时间，以提供通过所述采样装置从土壤中抽出溶液的抽吸，并且在预定义的采样周期结束时自动停止真空源并突然释放真空。

    DEVICE AND METHOD FOR EXTRACTING LIQUID SAMPLES
    39.
    发明申请
    DEVICE AND METHOD FOR EXTRACTING LIQUID SAMPLES 审中-公开
    去除液体样品的装置和方法

    公开(公告)号：WO2004033077A3

    公开(公告)日：2004-07-01

    申请号：PCT/EP0310883

    申请日：2003-10-01

    申请人： MAX PLANCK GESELLSCHAFT ,  SANN HEINER ,  BOCK ANDREAS ,  REICHL UDO

    发明人： SANN HEINER ,  BOCK ANDREAS ,  REICHL UDO

    IPC分类号： B67D7/72 ,  C12M1/26 ,  G01N1/14 ,  G01N1/34 ,  G01N1/10 ,  G01N1/20

    CPC分类号： G01N1/14 ,  C12M33/14 ,  G01N1/405 ,  Y10T137/314 ,  Y10T137/4259

    摘要： The invention relates to a device and a method for extracting liquid samples from containers (1) and/or tubes filled with a medium (2), especially from fermenters, via a filter membrane (5) by means of a partial vacuum. Said filter membrane (5) arranged inside a sample probe (3) consists of a material acting as a sterile boundary, a supply line (6) which can be used to guide gas and a discharge line (7) which can be used to guide the sample being arranged on the sterile boundary side (5a) of the filter membrane (5).

    摘要翻译： 本发明涉及一种装置和用于从介质取液体样品的方法（2）填充的容器（1）和/或管，特别是从发酵罐，通过过滤膜（5）通过负压的装置，其中，所述（一个试样探针3内 ）布置的过滤器膜片（5）由一个用作无菌边界材料制成，其中（滤膜的上边界5a的无菌侧）（5）可将其转化供给线的气体（6）和（7）被布置在样品可执行排出管线。

    INJECTION NEEDLE AND METHOD FOR TRANSFERRING A REPRESENTATIVE FLUID SAMPLE INTO A SAMPLE BOTTLE BY MEANS OF A SUCH INJECTION NEEDLE
    40.
    发明申请
    INJECTION NEEDLE AND METHOD FOR TRANSFERRING A REPRESENTATIVE FLUID SAMPLE INTO A SAMPLE BOTTLE BY MEANS OF A SUCH INJECTION NEEDLE 审中-公开
    注射针和通过这种注射针将代表性液体转移到样品瓶中的方法

    公开(公告)号：WO2004025271A1

    公开(公告)日：2004-03-25

    申请号：PCT/NO2003/000317

    申请日：2003-09-16

    申请人： FJERDINGSTAD, Sølve

    发明人： FJERDINGSTAD, Sølve

    IPC分类号： G01N1/00

    CPC分类号： G01N1/14 ,  G01N2001/105 ,  G01N2001/1427 ,  G01N2001/1445 ,  G01N2001/2085

    摘要： An injection needle particularly intended for transferring a representative fluid sample into a sample bottle (1) which is closed by a membrane (2) made from a rubber elastic material. The needle comprises a tubular inner wall (6) having a needle point (8), and a tubular outer wall (10) concentrically surrounding and radially spaced from the inner wall (6) at least along a portion thereof distant from the needle point (8) and, at its end facing the needle point, having a conically tapering portion (12) sealingly engaging the inner wall (6). The outer wall (10) is provided with at least two apertures (14, 16) spaced longitudinally of the needle. When using the injection needle for the above purpose, fluid is injected into the sample bottle (1) from a fluid source of interest, by inserting the injection needle into the sample bottle through the membrane to a level at which the penetrated portion of the membrane (2) sealingly engages the outer wall (10) of the needle between the spaced apertures (14, 16) in the outer wall, such that initially some of the fluid that is injected into the bottle is allowed to flow into the annulus between the inner and outer walls of the needle (4), through the aperture (14) of the outer wall at the inside of the membrane, and hence out through the aperture (16) of the outer wall at the outside of the membrane.

    摘要翻译： 一种特别用于将代表性流体样品转移到由橡胶弹性材料制成的膜（2）封闭的样品瓶（1）中的注射针。 该针包括具有针尖（8）的管状内壁（6）和与内壁（6）同心地围绕并径向间隔开的管状外壁（10），至少沿着远离针尖的部分 8），并且在其面向针尖的端部处具有密封地接合内壁（6）的圆锥形锥形部分（12）。 外壁（10）设置有至少两个彼此纵向间隔开的孔（14,16）。 当为了上述目的而使用注射针时，将流体从感兴趣的流体源注入到样品瓶（1）中，通过将注入针通过膜插入到样品瓶中至达到膜的穿透部分的水平 （2）密封地将针的外壁（10）密封地接合在外壁上的间隔开的孔（14,16）之间，使得最初一些注入到瓶中的流体被允许流入环 针（4）的内壁和外壁穿过膜外侧的外壁的孔（14），从而穿过膜外侧的外壁的孔（16）。