公开(公告)号：WO02059257A3

公开(公告)日：2002-12-19

申请号：PCT/IB0102737

申请日：2001-10-31

Applicant: COMMW SCIENT IND RES ORG ,  GRAINS RES & DEV CORP

Inventor： WATERHOUSE PETER ,  WANG MING-BO ,  ABBOTT DAVID

IPC: C07K14/08 ,  C12N15/82 ,  C12N15/11

CPC classification number: C07K14/005 ,  C12N15/8283 ,  C12N2770/00022

Abstract: The invention provides a DNA molecule comprising a plant-operable promoter operably linked to a DNA region that is capable of being transcribed in the cells of a cereal plant to produce RNA comprising inverted repeat sequence least about 19 nucleotides from the sequence of an RNA dependent RNA polymerase gene of Barley Yellow Dwarf Virus (BYDV). The DNA molecule is useful for reducing expression of the viral RNA dependant RNA polymerase and for enhancing the resistance of cereal crops to BYDV, optionally in the presence of a viral promoter that normally inactivates other modes of post transcriptional gene silencing. Methods are provided for producing transgenic cereal plant lines comprising the DNA molecule of the invention integrated into their genome, and selecting those lines having resistance to BYDV infection. Transgenic plants having enhanced resistance to BYDV are also provided.

Abstract translation: 本发明提供了一种DNA分子，其包含可操作地连接到能够在谷物植物的细胞中转录的DNA区的植物可操作的启动子，以产生包含来自RNA依赖性RNA序列的至少约19个核苷酸的反向重复序列 大麦黄矮病毒（BYDV）聚合酶基因。 该DNA分子可用于减少病毒RNA依赖性RNA聚合酶的表达并增强谷类作物对BYDV的抗性，任选地在病毒启动子存在下，其通常使其他模式的转录后基因沉默失活。 提供了用于生产包含整合到其基因组中的本发明的DNA分子的转基因谷物植物系的方法，并选择具有抗BYDV感染的那些系。 还提供了对BYDV具有增强抗性的转基因植物。

公开(公告)号：WO0216974A3

公开(公告)日：2002-07-18

申请号：PCT/EP0109712

申请日：2001-08-22

Applicant: NOVARTIS AG ,  NOVARTIS ERFIND VERWALT GMBH ,  COMMW SCIENT IND RES ORG ,  QIU YONGXING ,  WINTERTON LYNN COOK ,  LALLY JOHN MARTIN ,  CHABRECEK PETER ,  PASIC PAUL ,  GRIESSER HANS JOERG ,  KAMBOURIS PETER

Inventor： QIU YONGXING ,  WINTERTON LYNN COOK ,  LALLY JOHN MARTIN ,  CHABRECEK PETER ,  PASIC PAUL ,  GRIESSER HANS JOERG ,  KAMBOURIS PETER

IPC: G02C7/04 ,  A61L27/34 ,  C08J7/04 ,  C08J7/16 ,  G02B1/04 ,  G02B1/14 ,  G02B1/10

CPC classification number: C08J7/16 ,  A61L27/34 ,  G02B1/043 ,  Y10T428/31511 ,  Y10T428/31663 ,  Y10T428/31667 ,  Y10T428/31909 ,  Y10T428/31928

Abstract: The invention relates to a process for coating a material surface, comprising the steps of: (a) applying to the material surface a tie layer comprising a polyionic material; (b) covalently binding a bifunctional compound comprising an ethylenically unsaturated double bond to the tie layer; and (c) graft polymerizing a hydrophilic monomer onto the compound comprising the ethylenically unsaturated double bond. The coated articles that are obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.

Abstract translation: 本发明涉及一种用于涂覆材料表面的方法，包括以下步骤：（a）向材料表面施加包含聚离子材料的粘结层; （b）将包含烯键式不饱和双键的双官能化合物共价结合到粘结层上; 和（c）将亲水性单体接枝聚合到包含烯属不饱和双键的化合物上。 通过本发明的方法可获得的涂覆制品具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的所需特性，因此可用于制造生物医学制品如眼科装置。

公开(公告)号：WO1982000513A1

公开(公告)日：1982-02-18

申请号：PCT/AU1981000106

申请日：1981-08-07

Applicant: COMMW SCIENT IND RES ORG ,  BEARDSLEY R

Inventor： COMMW SCIENT IND RES ORG

IPC: G01B07/28

CPC classification number: G01B7/284

Abstract: An instrument and method for measuring a peripheral contour of a cylindrical-form, helically threaded workpiece (14) wherein the workpiece is mounted for rotation about its longitudinal axis and a measuring stylus (34) contacts the periphery of the workpiece so as to be able to move both parallel to, and perpendicularly of, the longitudinal axis of the workpiece, and as the workpiece is rotated about its longitudinal axis rotary movement of the workpiece and radial movement of the stylus as it follows a peripheral contour of the workpiece are converted to respective electrical signals representative of the angular rotational position of the workpiece and the radial position of the stylus.

Abstract translation: 一种用于测量圆柱形螺旋螺纹工件（14）的周边轮廓的仪器和方法，其中所述工件被安装成围绕其纵向轴线旋转，并且测量触针（34）接触所述工件的周边，从而能够 以平行于和垂直于工件的纵向轴线移动，并且随着工件围绕其纵向轴线旋转工件的旋转运动并且随着工件的周边轮廓的跟踪，触针的径向运动被转换为 相应的电信号表示工件的角度旋转位置和触针的径向位置。

公开(公告)号：WO1982000094A1

公开(公告)日：1982-01-21

申请号：PCT/AU1981000082

申请日：1981-07-02

Applicant: COMMW SCIENT IND RES ORG ,  LABY R ,  KAUTZNER B ,  BURNS R

Inventor： COMMW SCIENT IND RES ORG

IPC: A61K09/22

CPC classification number: A61K9/0068 ,  A61D7/00 ,  A61M31/002

Abstract: Une composition a liberation controlee pour administrer un agent therapeutique a un ruminant, utilisant un dispositif intraruminal, consiste en une pilule comprimee ou bol comprenant l'agent therapeutique, un materiau de support et facultativement un agent liant et/ou de glissement. Le materiau de support est constitue d'un materiau tensioactif ou d'un agent emulsifiant pouvant former une pilule ou bol coherent dans un moule sous pression lorsqu'il est melange a l'agent therapeutique et pouvant absorber de l'eau a l'interface pilule/eau, lorsqu'il est comprime en pilule ou bol, pour produire le gonflement du materiau et un coloide d'eau resultant; l'effort d'affaissement critique de ce coloide est sensiblement plus faible que celui du materiau sec et il n'est pas diminue de maniere significative par l'eau absorbee ulterieurement, le coloide etant a meme de reduire sensiblement la vitesse de penetration ulterieure de l'eau dans le corps du materiau recouvert de coloide. Le dispositif intraruminal decrit fait partie de l'invention.

公开(公告)号：WO2013185184A3

公开(公告)日：2014-02-13

申请号：PCT/AU2013000639

申请日：2013-06-14

Applicant: COMMW SCIENT IND RES ORG ,  GRAINS RES & DEV CORP ,  NUSEED PTY LTD

Inventor： PETRIE JAMES ROBERTSON ,  SINGH SURINDER PAL ,  DE FEYTER ROBERT CHARLES

IPC: A01H5/00 ,  C07H21/04 ,  C11B1/10 ,  C12N15/52 ,  C12N15/79 ,  C12N15/82

CPC classification number: C11C3/00 ,  A23K20/158 ,  A23L33/12 ,  A23V2002/00 ,  A61K31/231 ,  A61K31/232 ,  A61K36/31 ,  A61K2236/35 ,  C07C67/02 ,  C07K14/415 ,  C11B1/00 ,  C11B1/10 ,  C11C3/003 ,  C11C3/06 ,  C12N9/1025 ,  C12N15/8247

Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially docosahexaenoic acid, in recombinant plant cells.

Abstract translation: 本发明涉及在重组植物细胞中合成长链多不饱和脂肪酸，特别是二十二碳六烯酸的方法。

公开(公告)号：WO2014008263A2

公开(公告)日：2014-01-09

申请号：PCT/US2013049069

申请日：2013-07-02

Applicant: JACKSON H M FOUND MILITARY MED ,  COMMW SCIENT IND RES ORG ,  STATE OF QUEENSLAND DEPT OF AGRICULTURE FISHERIES AND FORESTRY

Inventor： WANG LINFA ,  MARSH GLENN A ,  FIELD HUME ,  BRODER CHRISTOPHER

IPC: A61K39/155

CPC classification number: C12Q1/701 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/543 ,  C07K14/005 ,  C07K16/1027 ,  C07K2317/76 ,  C12N7/00 ,  C12N2760/18221 ,  C12N2760/18222 ,  C12N2760/18231 ,  C12N2760/18234 ,  C12Q2600/136

Abstract: The present invention is directed towards a novel virus, called Cedar Virus, and its methods of use.

Abstract translation: 本发明针对一种称为Cedar Virus的新型病毒及其使用方法。

公开(公告)号：WO2011038459A8

公开(公告)日：2011-05-12

申请号：PCT/AU2010001284

申请日：2010-09-30

Applicant: COMMW SCIENT IND RES ORG ,  ZILTEK PTY LTD ,  MCLAUGHLIN MICHAEL JOHN

Inventor： MCLAUGHLIN MICHAEL JOHN

IPC: C02F11/00 ,  A62D3/00 ,  A62D3/30 ,  A62D3/33 ,  A62D3/36 ,  A62D101/00 ,  C09K17/00 ,  C09K17/08

CPC classification number: B09B3/0041 ,  B09C1/08 ,  C02F1/281 ,  C02F1/5236 ,  C02F11/008

Abstract: The invention relates to the use of a by-product from drinking water treatment, namely alum sludge, in a method and composition for the stabilisation of contaminants (e.g. arsenic and polycyclic aromatic hydrocarbon) in materials such as soils and other solid or semi-solid matrix types. The composition may also comprise a reactive carbon material such as activated carbon. Further, the composition may comprise a solidifier such as calcium silicate-based cement to enable the stabilisation and immobilisation of contaminants.

Abstract translation: 本发明涉及饮用水处理中的副产物，即明矾污泥在用于稳定污垢（例如砷和多环芳烃）的方法和组合物中的用途，所述污染物例如土壤和其他固体或半固体 矩阵类型。 该组合物还可以包含活性碳材料如活性炭。 此外，组合物可以包含固化剂，例如硅酸钙基水泥，以使污染物稳定和固定。

公开(公告)号：WO2005103253A8

公开(公告)日：2006-01-05

申请号：PCT/AU2005000571

申请日：2005-04-22

Applicant: COMMW SCIENT IND RES ORG ,  SINGH SURINDER PAL ,  ROBERT STANLEY SURESH ,  NICHOLS PETER DAVID ,  BLACKBURN SUSAN IRENE ELLIS ,  ZHOU XUE-RONG ,  PETRIE JAMES ROBERTSON ,  GREEN ALLAN GRAHAM

Inventor： SINGH SURINDER PAL ,  ROBERT STANLEY SURESH ,  NICHOLS PETER DAVID ,  BLACKBURN SUSAN IRENE ELLIS ,  ZHOU XUE-RONG ,  PETRIE JAMES ROBERTSON ,  GREEN ALLAN GRAHAM

IPC: A01H5/00 ,  A23K1/00 ,  A23K1/14 ,  A23K1/16 ,  C11B1/00 ,  C11B1/10 ,  C12N9/02 ,  C12N9/10 ,  C12N15/11 ,  C12N15/52 ,  C12N15/82 ,  C12P7/64

CPC classification number: C12P7/6427 ,  A01H5/10 ,  A23K10/12 ,  A23K10/30 ,  A23K20/158 ,  C11B1/10 ,  C11C3/12 ,  C12N9/0071 ,  C12N9/0083 ,  C12N9/1029 ,  C12N15/52 ,  C12N15/8247 ,  C12P7/64 ,  C12P7/6472 ,  C12Y114/19004 ,  Y02P20/52

Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.

Abstract translation: 本发明涉及在重组细胞如酵母或植物细胞中合成长链多不饱和脂肪酸，特别是二十碳五烯酸，二十二碳五烯酸和二十二碳六烯酸的方法。 还提供了产生长链多不饱和脂肪酸的重组细胞或植物。 此外，本发明涉及一组可用于合成长链多不饱和脂肪酸的方法中的脱酰酶或延伸酶活性的新酶。

公开(公告)号：WO2004009227A3

公开(公告)日：2005-11-24

申请号：PCT/AU0300935

申请日：2003-07-23

Applicant: COMMW SCIENT IND RES ORG ,  ADHIKARI RAJU ,  GUNATILLAKE PATHIRAJA A

Inventor： ADHIKARI RAJU ,  GUNATILLAKE PATHIRAJA A

IPC: A61F2/00 ,  A61K31/74 ,  A61L27/18 ,  A61L27/58 ,  A61L31/06 ,  B01J20060101 ,  C08G18/10 ,  C08G18/32 ,  C08G18/77 ,  C08G18/80 ,  C08K3/32 ,  C08K5/00

CPC classification number: A61K47/482 ,  A61F2/30 ,  A61F2/30756 ,  A61K31/74 ,  A61L27/18 ,  A61L27/3817 ,  A61L27/3834 ,  A61L27/50 ,  A61L27/58 ,  C08G18/3206 ,  C08G18/8022 ,  C08L75/04

Abstract: The present invention relates to biocompatible, biodegradable polyurethane/urea polymeric compositions that are capable of in-vivo curing with low heat generation to form materials suitable for use in scaffolds in tissue engineering applications such as bone and cartilage repair. The polymers are desirably flowable and injectable and can support living biological components to aid in the healing process. They may be cured ex-vivo for invasive surgical repair methods, or alternatively utilized for relatively non-invasive surgical repair methods such as by arthroscope. The invention also relates to prepolymers useful in the preparation of the polymeric compositions, and to methods of treatment of damaged tissue using the polymers of the invention.

Abstract translation: 本发明涉及生物相容性可生物降解的聚氨酯/尿素聚合物组合物，其能够在低发热下体内固化以形成适合用于组织工程应用如骨和软骨修复中的支架的材料。 聚合物理想地是可流动和可注射的，并且可以支持活的生物组分以帮助愈合过程。 它们可以用于侵入性手术修复方法离体固化，或者可以用于相对非侵入性的手术修复方法，例如通过关节镜。 本发明还涉及可用于制备聚合物组合物的预聚物，以及使用本发明聚合物处理受损组织的方法。

公开(公告)号：WO2004053472A8

公开(公告)日：2005-08-18

申请号：PCT/AU0301641

申请日：2003-12-10

Applicant: COMMW SCIENT IND RES ORG ,  SOWERBY BRIAN DAVID ,  TICKNER JAMES RICHARD

Inventor： SOWERBY BRIAN DAVID ,  TICKNER JAMES RICHARD

IPC: G01N23/09 ,  G01N23/10 ,  G01T1/16 ,  G01T3/00 ,  G01V5/00

CPC classification number: G01N23/09

Abstract: The invention concerns radiographic equipment. The equipment includes a source of substantially mono-energetic fast neutrons produced via the deuterium-tritium or deuterium-deuterium fusion reactions, comprising a sealed-tube or similar generator for producing the neutrons. The equipment further includes a source of X-rays or gamma-rays of sufficient energy to substantially penetrate an object to be imaged and a collimating block surrounding the neutron and gamma-ray sources, apart from the provision of one or more slots emitting substantially fan-shaped radiation beams. Further included is a detector array comprising a multiplicity of individual scintillator pixels to receive radiation energy from the sources and convert the received energy into light pulses, the detector array aligned with the fan-shaped beams emitted from the source collimator and collimated to substantially prevent radiation other than that directly transmitted from the sources reaching the array. Conversion means are included for converting the light pulses produced in the scintillators into electrical signals. Conveying means are included for conveying an object between the sources and the detector array. Computing means are included for determining from the electrical signals the attenuation of the neutrons and the X-ray or gamma-ray beams and to generate output representing the mass distribution and composition of the object interposed between the source and detector array. The equipment further includes a display means for displaying images based on the mass distribution and the composition of the object being scanned.

Abstract translation: 本发明涉及射线照相设备。 该设备包括通过氘 - 氚或氘 - 氘聚变反应产生的基本上单能的快中子源，包括用于产生中子的密封管或类似的发生器。 设备还包括具有足够能量的X射线或伽马射线源，以基本上穿透要成像的物体和围绕中子和伽马射线源的准直块，除了提供一个或多个发射大致风扇的槽 形辐射束。 进一步包括的检测器阵列包括多个独立的闪烁体像素以接收来自源的辐射能量并将接收到的能量转换成光脉冲，检测器阵列与从源准直仪发出的扇形光束对准并准直以基本上防止辐射 除了从源到达阵列的直接传输。 包括用于将闪烁体中产生的光脉冲转换为电信号的转换装置。 包括传送装置，用于在物体源和检测器阵列之间传送物体。 包括计算装置，用于从电信号确定中子和X射线或γ射线束的衰减，并产生表示介于源和检测器阵列之间的物体的质量分布和组成的输出。 该设备还包括用于基于质量分布和被扫描对象的组成来显示图像的显示装置。