公开(公告)号：WO2008014505A2

公开(公告)日：2008-01-31

申请号：PCT/US2007/074710

申请日：2007-07-30

Applicant: ISP INVESTMENTS INC. ,  BERTZ, Steven H. ,  DRZEWINSKI, Michael D. ,  MAKAROVSKY, Ilya

Inventor： BERTZ, Steven H. ,  DRZEWINSKI, Michael D. ,  MAKAROVSKY, Ilya

IPC: A61K8/37

CPC classification number: A61K8/365 ,  A61K8/34 ,  A61K8/37 ,  A61Q13/00 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/02

Abstract: In accordance with this invention, there is provided a blend which comprises the reaction product of an aryl alcohol and an alkyl or aryl carboxylic acid and the reaction product of a C 1 -C 22 linear or branched, saturated or unsaturated alcohol and a hydroxy acid. The blend provides enhanced solubilization of active and functional organic compounds.

Abstract translation: 根据本发明，提供了一种共混物，其包含芳基醇和烷基或芳基羧酸的反应产物和C 1 -C 12烷基或芳基羧酸的反应产物， 直链或支链的饱和或不饱和醇和羟基酸。 该混合物提供活性和功能性有机化合物的增强的增溶作用。

公开(公告)号：WO2008014379A1

公开(公告)日：2008-01-31

申请号：PCT/US2007/074429

申请日：2007-07-26

Applicant: ISP INVESTMENTS INC. ,  PROSISE, William E. ,  HILSENBECK, Jay

Inventor： PROSISE, William E. ,  HILSENBECK, Jay

IPC: A61K8/00 ,  A61Q11/00

CPC classification number: A61K8/347 ,  A61K8/73 ,  A61K8/8164 ,  A61Q11/00

Abstract: An oral care composition comprising a copolymer of an alkyl vinyl ether and maleic acid or anhydride, a surface active vegetable gum, and a non-cationic antibacterial agent. The composition exhibits increased uptake and retention of the non-cationic antibacterial agent on application to teeth.

Abstract translation: 一种包含烷基乙烯基醚和马来酸或酸酐的共聚物，表面活性植物胶和非阳离子抗菌剂的口腔护理组合物。 该组合物在施用于牙齿时表现出增加的非阳离子抗菌剂的吸收和保留。

公开(公告)号：WO2007087278A3

公开(公告)日：2007-12-21

申请号：PCT/US2007001717

申请日：2007-01-22

Applicant: ISP INVESTMENTS INC ,  BERTZ STEVEN H ,  MAKAROVSKY ILYA ,  LAURA DONNA N

Inventor： BERTZ STEVEN H ,  MAKAROVSKY ILYA ,  LAURA DONNA N

IPC: A61K8/00

CPC classification number: A61K8/37 ,  A61K8/35 ,  A61K8/375 ,  A61K8/4966 ,  A61Q17/04 ,  A61Q19/08 ,  Y02P20/582

Abstract: An active or functional organic compound is solubilized by an ester of an aryl alcohol, e.g., phenethyl, benzyl or substituted benzyl alcohol, and an alkyl or cycloalkyl carboxylic acid, or by a carbonate of said aryl alcohol and an alkyl or cycloalkyl carbonic acid.

Abstract translation: 活性或官能的有机化合物通过芳基醇例如苯乙基，苄基或取代的苯甲醇，和烷基或环烷基羧酸的酯，或者通过所述芳基醇和烷基或环烷基碳酸的碳酸酯来溶解。

公开(公告)号：WO2006041506A3

公开(公告)日：2007-12-21

申请号：PCT/US2005000825

申请日：2005-01-10

Applicant: ISP INVESTMENTS INC ,  BERTZ STEVEN H ,  OROFINO STEVEN A ,  BOTSCHKA ELLEN S ,  GOMEZ BLANCA ,  GORCEA MIHAELA ,  MAKAROVSKY ILYA ,  LAURA DONNA N

Inventor： BERTZ STEVEN H ,  OROFINO STEVEN A ,  BOTSCHKA ELLEN S ,  GOMEZ BLANCA ,  GORCEA MIHAELA ,  MAKAROVSKY ILYA ,  LAURA DONNA N

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/06 ,  A61K8/37 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  C07C67/03 ,  C07C67/08

CPC classification number: A61K8/37 ,  A61K8/0229 ,  A61Q1/06 ,  A61Q5/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/08 ,  C07C67/03 ,  C07C67/08 ,  C09G1/06 ,  C07C69/78 ,  C07C69/80 ,  C07C69/76

Abstract: An active or functional organic compound is solubilized in a diaryl organic compound having a polar or polarizable functional group therein, as a solvent, cosolvent or additive, to form a composition thereof. Representative active or functional organic compounds include those present in personal care products, e.g., sunscreens containing UVA/UVB absorbing compounds, such as avobenzone, benzophenone-3, and 4-methylbenzylidene camphor. Such compositions also show increased SPF, UVA/UVB absorbance ratio, and critical wavelength performance properties.

Abstract translation: 活性或功能性有机化合物溶解在其中具有极性或可极化官能团的二芳基有机化合物中，作为溶剂，共溶剂或添加剂，以形成其组合物。 代表性的活性或功能性有机化合物包括存在于个人护理产品中的那些，例如含有UVA / UVB吸收化合物的防晒剂，例如阿伏苯宗，二苯甲酮-3和4-甲基亚苄基樟脑。 这些组合物还显示增加的SPF，UVA / UVB吸光度比和临界波长性能。

公开(公告)号：WO2007103316A2

公开(公告)日：2007-09-13

申请号：PCT/US2007/005601

申请日：2007-03-06

Applicant: ISP INVESTMENTS INC. ,  RAILKAR, Sudhir ,  CHICK, Adem ,  ZARATE, Walter

Inventor： RAILKAR, Sudhir ,  CHICK, Adem ,  ZARATE, Walter

IPC: F24F7/02

CPC classification number: F24F7/025 ,  E04D13/174

Abstract: There is provided a ridge ventilation system that comprises a ridge slot disposed longitudinally in a ridge of a roof and a fan disposed in the ridge slot for actively exhausting air from an attic substantially enclosed by the roof, sidewalls and ceiling into the ambient atmosphere. There is further provided a method for ventilating that comprises disposing a ridge slot longitudinally in a ridge of the roof and operating a fan disposed in the ridge slot to actively exhaust air from the attic into the ambient atmosphere. Lastly, there is provided a method for installing the ridge ventilation system that comprises constructing a ridge slot longitudinally disposed in a ridge of the roof and disposing a fan in the ridge slot to actively exhaust air from the attic into the ambient atmosphere.

Abstract translation: 提供了一种脊部通风系统，其包括纵向设置在屋顶的脊部中的脊槽和设置在脊槽槽中的风扇，用于主动地将空气从基本上由屋顶，侧壁和天花板封闭的阁楼排出到周围大气中。 还提供了一种通风方法，其包括在屋脊的纵向纵向设置脊缝槽并操作设置在脊槽槽中的风扇以主动地将空气从阁楼排出到环境大气中。 最后，提供了一种用于安装脊通风系统的方法，该方法包括：构造纵向设置在屋脊的脊中的脊槽槽，并将风扇设置在脊槽槽中，以将空气主动地从阁楼排出到周围空气中。

公开(公告)号：WO2007014392A3

公开(公告)日：2007-06-21

申请号：PCT/US2006029821

申请日：2006-07-28

Applicant: ISP INVESTMENTS INC ,  OLSEN STEPHEN ,  DONEY JOHN ALFRED ,  SHORES CHRISTOPHEN STEVEN

Inventor： OLSEN STEPHEN ,  DONEY JOHN ALFRED ,  SHORES CHRISTOPHEN STEVEN

IPC: A61K9/16 ,  A61K9/26 ,  A61K9/36 ,  A61K9/48 ,  A61K31/122 ,  A61P9/00

CPC classification number: A61K31/122 ,  A61K9/1635 ,  A61K9/1647 ,  A61K9/1652 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2866 ,  A61K9/4866 ,  A61K31/12

Abstract: Benzoquinone compositions of enhanced solubility and bioavailability are described that contain at least one benzoquinone with at least one solubility-enhancing polymer. In one embodiment, the benzoquinone is coenzyme Q10. Described methods to produce the bioenhanced products comprise dry blending and solvent spray drying. One aspect of the method includes the steps of providing a mixture comprising benzoquinone, a solubility-enhancing polymer and a solvent and removing the solvent to form amorphous benzoquinone. Products made by the invention's compositions and methods include pharmaceuticals, nutraceuticals, cosmetic, and personal care products for man and animal.

Abstract translation: 描述了具有增强的溶解性和生物利用度的苯醌组合物，其含有至少一种具有至少一种溶解度增强聚合物的苯醌。 在一个实施方案中，苯醌是辅酶Q10。 生产生物增强产品的描述方法包括干混和溶剂喷雾干燥。 该方法的一个方面包括提供包含苯醌，溶解度增强聚合物和溶剂并除去溶剂以形成无定形苯醌的混合物的步骤。 通过本发明的组合物和方法制备的产品包括用于人和动物的药物，营养制品，化妆品和个人护理产品。

公开(公告)号：WO2007064397A2

公开(公告)日：2007-06-07

申请号：PCT/US2006/038194

申请日：2006-09-28

Applicant: ISP INVESTMENTS INC. ,  MINGTAI CHEMICAL CO., LTD. ,  HALDAR, Rama ,  RAY, Dipan, B. ,  BEE, Timothy, G. ,  ETIENNE, Sidney ,  CHENG, Su-Jane

Inventor： HALDAR, Rama ,  RAY, Dipan, B. ,  BEE, Timothy, G. ,  ETIENNE, Sidney ,  CHENG, Su-Jane

IPC: A61K9/20 ,  B27N3/00

CPC classification number: A61K9/2095 ,  A61K9/1641 ,  A61K9/1652 ,  A61K9/2031 ,  A61K9/2054 ,  A61K9/2077

Abstract: Tablets of a pharmaceutical, nutritional or vitamin active compound or composition, e.g. a poorly compressible drug are made by direct compression using a synergistic binder composition of co-processed (a) copolymer of vinylpyrrolidone (VP) and vinyl acetate (VA) and (b) microcrystalline cellulose (MCC), in a wt. ratio of (a):(b) of 1 -30:99-70, which is spray dried to provide a readily compressible excipient binder powder for such active. The tablets obtained herein have advantageous hardness and friability at an acceptable compression force.

Abstract translation: 药物，营养或维生素活性化合物或组合物的片剂，例如片剂。 （a）乙烯基吡咯烷酮（VP）和乙酸乙烯酯（VA）的共聚物和（b）微晶纤维素（MCC）的协同粘合剂组合物通过直接压制制备不良可压缩药物， （a）：（b）的比例为1-30：99-70，其被喷雾干燥以提供用于这种活性物质的易于压缩的赋形剂粘合剂粉末。 本文获得的片剂在可接受的压缩力下具有有利的硬度和脆性。

公开(公告)号：WO2007008484A3

公开(公告)日：2007-04-26

申请号：PCT/US2006025976

申请日：2006-06-30

Applicant: ISP INVESTMENTS INC ,  WINGENFELD ANDREA ,  OCHS CHRISTIANE

Inventor： WINGENFELD ANDREA ,  OCHS CHRISTIANE

IPC: A01N25/00

CPC classification number: A01N43/80 ,  A01N25/02 ,  A01N31/04 ,  A01N33/12 ,  A01N35/02 ,  A01N35/08 ,  A01N37/06 ,  A01N37/40 ,  A01N39/00 ,  A01N43/16 ,  A01N47/12 ,  A01N47/14 ,  A01N47/44 ,  A01N2300/00

Abstract: The invention relates to a microbicidal composition which comprises a mixture of at least two components, the first component being 2-methyl-3-isothiazolone (MIT) and the second component being at least one active compound selected from the following groups of active compounds : a) compound having activated methylol groups b) quats or polyquats c) carbamates d) organic acids e) aromatic alcohols.

Abstract translation: 本发明涉及一种杀微生物组合物，其包含至少两种组分的混合物，第一组分为2-甲基-3-异噻唑酮（MIT），第二组分为至少一种选自下列活性化合物的活性化合物： a）具有活化羟甲基的化合物b）quats或polyquats c）氨基甲酸酯d）有机酸e）芳族醇。

公开(公告)号：WO2007032969A3

公开(公告)日：2007-03-22

申请号：PCT/US2006/034585

申请日：2006-09-06

Applicant: ISP INVESTMENTS INC. ,  HALDAR, Rama ,  RAY, Dipan, B. ,  DREFKO, William ,  ETIENNE, Sidney

Inventor： HALDAR, Rama ,  RAY, Dipan, B. ,  DREFKO, William ,  ETIENNE, Sidney

IPC: B29B9/00 ,  B29C43/06

Abstract: A process and apparatus for forming agglomerates of a powder composition of an active and binder such as a homopolymer or copolymer which includes passing the composition through a hot roller compactor to heat said binder material above its glass transition temperature.

公开(公告)号：WO2007032969A2

公开(公告)日：2007-03-22

申请号：PCT/US2006034585

申请日：2006-09-06

Applicant: ISP INVESTMENTS INC ,  HALDAR RAMA ,  RAY DIPAN B ,  DREFKO WILLIAM ,  ETIENNE SIDNEY

Inventor： HALDAR RAMA ,  RAY DIPAN B ,  DREFKO WILLIAM ,  ETIENNE SIDNEY

IPC: C11D17/00

CPC classification number: A61K9/2095 ,  A61K9/1635 ,  A61K9/1694 ,  A61K9/2027

Abstract: A process and apparatus for forming agglomerates of a powder composition of an active and binder such as a homopolymer or copolymer which includes passing the composition through a hot roller compactor to heat said binder material above its glass transition temperature.

Abstract translation: 一种用于形成活性物质和粘合剂如均聚物或共聚物的粉末组合物的附聚物的方法和装置，其包括使组合物通过热辊压实机将所述粘合剂材料加热到高于其玻璃化转变温度。