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公开(公告)号：WO2005112644A3
公开(公告)日：2005-12-01
申请号：PCT/US2005/016148
申请日：2005-05-10
Applicant: GLAXO GROUP LIMITED , LAINE, Dramane, I. , McCLELAND, Brent, W. , NEIPP, Christopher, E. , PALOVICH, Michael, R.
Inventor： LAINE, Dramane, I. , McCLELAND, Brent, W. , NEIPP, Christopher, E. , PALOVICH, Michael, R.
IPC: C07D453/02
Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
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公开(公告)号：WO2005104745A2
公开(公告)日：2005-11-10
申请号：PCT/US2005/014386
申请日：2005-04-27
Applicant: GLAXO GROUP LIMITED , LAINE, Dramane, I. , PALOVICH, Michael, R. , MCCLELAND, Brent, W. , NEIPP, Christopher, E. , THOMAS, Sonia, M.
Inventor： LAINE, Dramane, I. , PALOVICH, Michael, R. , MCCLELAND, Brent, W. , NEIPP, Christopher, E. , THOMAS, Sonia, M.
IPC: C07D453/02
CPC classification number: C07D453/02 , A61K31/439
Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
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公开(公告)号：WO2005094251A2
公开(公告)日：2005-10-13
申请号：PCT/US2004/008025
申请日：2004-03-17
Applicant: GLAXO GROUP LIMITED , BUSCH-PETERSEN, Jakob , COOPER, Anthony, W., J. , LAINE, Dramane, I. , PALOVICH, Michael, R. , WAN, Zehong , YAN, Hongxing , ZHU, Chongjie
Inventor： BUSCH-PETERSEN, Jakob , COOPER, Anthony, W., J. , LAINE, Dramane, I. , PALOVICH, Michael, R. , WAN, Zehong , YAN, Hongxing , ZHU, Chongjie
IPC: C07D487/08
CPC classification number: C07D487/08
Abstract: Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.
Abstract translation: 提供毒蕈碱性乙酰胆碱受体拮抗剂及其使用方法。
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公开(公告)号：WO2005009439A1
公开(公告)日：2005-02-03
申请号：PCT/US2004/022947
申请日：2004-07-16
Applicant: GLAXO GROUP LIMITED , BELMONTE, Kristen, E. , BUSCH-PETERSEN, Jakob , LAINE, Dramane , PALOVICH, Michael, R.
IPC: A61K31/46
CPC classification number: C07D451/02
Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
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公开(公告)号：WO2005000231A3
公开(公告)日：2005-01-06
申请号：PCT/US2004/017892
申请日：2004-06-04
Applicant: SMITHKLINE BEECHAM CORPORATION , BUSCH-PETERSEN, Jakob , FU, Wei , KERNS, Jeffrey, K. , PALOVICH, Michael, R. , WIDDOWSON, Katherine, Louise
Inventor： BUSCH-PETERSEN, Jakob , FU, Wei , KERNS, Jeffrey, K. , PALOVICH, Michael, R. , WIDDOWSON, Katherine, Louise
IPC: C07D285/30
Abstract: This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
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Patent Agency Ranking
公开(公告)号：WO2004091482A2
公开(公告)日：2004-10-28
申请号：PCT/US2004/010641
申请日：2004-04-07
Applicant: GLAXO GROUP LIMITED , BUSCH-PETERSEN, Jakob , LAINE, Dramane, I. , PALOVICH, Michael, R. , MCCLELAND, Brent, W.
IPC: A61K
CPC classification number: C07D519/00 , C07D487/08
Abstract: Novel thiazole aniline compounds, pharmaceutical compositions, methods of making them and used therof in treating M 3 muscarinic acetylcholine receptor mediated diseases are disclosed
Abstract translation: 公开了新型噻唑苯胺化合物，药物组合物，制备方法和用于治疗M3毒蕈碱性乙酰胆碱受体介导的疾病的方法
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公开(公告)号：WO2004039775A3
公开(公告)日：2004-08-26
申请号：PCT/US0333964
申请日：2003-10-28
Applicant: SMITHKLINE BEECHAM CORP , BUSCH-PETERSEN JAKOB , PALOVICH MICHAEL R , WIDDOWSON KATHERINE L
Inventor： BUSCH-PETERSEN JAKOB , PALOVICH MICHAEL R , WIDDOWSON KATHERINE L
IPC: C07D295/26 , A61K31/495
CPC classification number: C07D295/26
Abstract: This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
Abstract translation: 本发明涉及式（I）至（VII）的新化合物及其组合物，其可用于治疗由趋化因子介导的疾病状态，白细胞介素-8（IL-8）。
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公开(公告)号：WO2004039775A2
公开(公告)日：2004-05-13
申请号：PCT/US2003/033964
申请日：2003-10-28
Applicant: SMITHKLINE BEECHAM CORPORATION , BUSCH-PETERSEN, Jakob , PALOVICH, Michael, R. , WIDDOWSON, Katherine, L.
IPC: C07D
CPC classification number: C07D295/26
Abstract: This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
Abstract translation: 本发明涉及可用于治疗由趋化因子白细胞介素-8（IL-8）介导的疾病状态的式（I）至（VII）的新型化合物及其组合物。 / p>
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公开(公告)号：WO0168033A3
公开(公告)日：2002-03-07
申请号：PCT/US0107745
申请日：2001-03-09
Applicant: SMITHKLINE BEECHAM CORP , PALOVICH MICHAEL R , WIDDOWSON KATHERINE L , NIE HONG
Inventor： PALOVICH MICHAEL R , WIDDOWSON KATHERINE L , NIE HONG
IPC: A61K31/18 , A61K31/40 , A61K31/42 , A61P1/02 , A61P1/04 , A61P1/18 , A61P7/00 , A61P7/02 , A61P7/04 , A61P7/10 , A61P9/00 , A61P9/04 , A61P9/10 , A61P9/12 , A61P9/14 , A61P11/00 , A61P11/02 , A61P11/06 , A61P11/14 , A61P13/12 , A61P15/06 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/04 , A61P19/06 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/28 , A61P25/32 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/14 , A61P31/20 , A61P31/22 , A61P33/06 , A61P35/00 , A61P37/00 , A61P37/02 , A61P37/08 , A61P39/00 , A61P41/00 , A61P43/00 , C07C335/18 , C07D207/48 , C07D261/02 , C07D261/08 , C07D265/02 , C07D295/135 , A61K31/196 , A61K31/216 , A61K31/222 , A61K31/277 , C07C311/47
CPC classification number: C07D261/02 , C07C335/18 , C07D207/48 , C07D265/02 , C07D295/135
Abstract: This invention relates to novel compounds of Formula (I), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
Abstract translation: 本发明涉及可用于治疗由趋化因子白细胞介素-8（IL-8）介导的疾病状态的式（I）的新化合物及其组合物。
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公开(公告)号：WO2012109415A1
公开(公告)日：2012-08-16
申请号：PCT/US2012/024428
申请日：2012-02-09
Applicant: GLAXOSMITHKLINE LLC , NEIPP, Christopher, E. , PALOVICH, Michael, R.
Inventor： NEIPP, Christopher, E. , PALOVICH, Michael, R.
CPC classification number: C07D405/12 , A61K31/35 , C07D309/08 , C07D309/14
Abstract: Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.
Abstract translation: 公开了具有药理活性的式（I）的4-氨基-2-丁烯酰胺，含有它们的药物组合物，以及用于治疗由组织蛋白酶C酶介导的疾病如慢性阻塞性肺疾病的方法。
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