公开(公告)号：WO99033072A1

公开(公告)日：1999-07-01

申请号：PCT/EP1998/008232

申请日：1998-12-17

IPC分类号： H01F1/34 ,  B03C1/32 ,  H01F1/44

CPC分类号： B03C1/32 ,  H01F1/44

摘要： The invention relates to a novel magnetic liquid and to a method and device for the production thereof. The aim of the invention is to produce a magnetic liquid which is based on a polar carrier liquid having a high saturation magnetization, i.e. having a high concentration of nanometer particles and a low viscosity, and to provide a method and device for the production thereof. To this end, a magnetic liquid is provided which comprises a saturation magnetization of at least 30 mT and a viscosity under 100 mPas at 40 DEG C, whereby the carrier liquid contains essentially no dissolved components of the outer adsorption layer. In addition, a method and device are provided for the production thereof.

摘要翻译： 本发明涉及一种新的磁性流体，以及它们的制备方法和装置。 本发明的目的还在于提供一种基于具有高饱和磁化强度的极性载液，即磁流体， 有高浓度的纳米颗粒的，并提供低粘度，并提供它们的生产方法和设备。 该目的是用具有至少30 1mT的饱和磁化强度，并在40℃下100mPa·s以下的粘度，其中所述载液基本上不包含所述外吸附剂层，制造和装置的方法的不溶解成分的磁性流体来实现的。

公开(公告)号：WO2022235949A2

公开(公告)日：2022-11-10

申请号：PCT/US2022/027893

申请日：2022-05-05

申请人： SALUS DISCOVERY, LLC ,  FLAMBEAU DIAGNOSTICS, LLC

发明人： BEEBE, Dave ,  MCMINN, Patrick ,  MULLINS, Brianna ,  WARRICK, Jay

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  G01N33/50 ,  G01N33/53 ,  G01N33/543 ,  G01N33/553 ,  G01N33/558 ,  G01N35/00 ,  B01L1/00 ,  B01L3/00 ,  B03C1/00 ,  B03C1/32 ,  C12Q1/6834 ,  G01N1/40 ,  B01J20/103 ,  B01J20/28042 ,  B01J20/28069 ,  B01L2200/0647 ,  B01L2200/16 ,  B01L2300/0829 ,  B01L3/502761 ,  C12Q1/6851 ,  C12Q1/701 ,  G01N33/54326

摘要： Systems, devices, compositions and methods for positioning and/or processing a target are provided. The invention includes systems, devices, methods and related compositions useful, for example, for the separation, isolation, purification, identification, detection and quantification of materials. Also provided are systems and methods for isolation, and/or detection and/or quantification of a target or analyte in a sample. Some systems, devices, compositions and methods comprise oil and aqueous phases stabilized in close proximity to each other. Some systems, devices and methods use a magnetic force to draw a target or carrier-bound through multiple layers. In some embodiments, systems and devices comprise reagents for detection of a target or analyte.

公开(公告)号：WO2019229674A1

公开(公告)日：2019-12-05

申请号：PCT/IB2019/054453

申请日：2019-05-29

申请人： KHALIFA UNIVERSITY OF SCIENCE AND TECHNOLOGY

发明人： ALHSEINAT, Emad ,  BANAT, Fawzi

IPC分类号： C02F1/48 ,  B03C1/32

摘要： A liquid desalination system is disclosed. The liquid desalination system includes a feed line having an inlet to receive liquid and an outlet to discharge the liquid. The liquid desalination system includes a magnet coupled to the feed line, the magnet to generate an oscillating magnetic field within the feed line and in opposition to the feed water flow. The removal of targeted ions can be achieved by manipulating the frequency and rate of the generated electromagnetic waves. The generated electromagnetic waves can be tuned to weaken the hydration bonds of that specific ion and facilitate its removal. The liquid desalination system generates an electric field across the feed line to enable the liquid to flow through the electric field. The electric field may attract sodium ions to a positive electrode and may attract chloride ions to a negative electrode, to desalinate the liquid in the feed line.

公开(公告)号：WO2017111583A1

公开(公告)日：2017-06-29

申请号：PCT/NL2016/050897

申请日：2016-12-20

申请人： FEELGOOD METALS B.V.

发明人： REM, Peter Carlo ,  BERKHOUT, Simon Petrus Maria

IPC分类号： B03C1/32

CPC分类号： B03C1/32

摘要： A system and method for magnetic density separation of products (1a, 1b). The system (10) comprises a magnet (2) configured to amplify a density gradient (D) in a magnetic liquid (L) for separating the products (1a, 1b) in the magnetic liquid (L) according to their different density (Da, Db). A plate shape (3) is disposed along a product path (P) where respective products (1b') travel through the magnetic liquid (L). A driving mechanism (4) is configured to drive the plate shape (3) with a reciprocating motion (R) for lowering a static friction of the respective products (1b") coming into contact with the plate shape (3). Accordingly, process continuity can be improved while maintaining a high separation efficiency, in particular by alleviating material build-up and clogging of products at the splitter and other surfaces with minimal disturbance to the process flow.

摘要翻译： 用于产品（1a，1b）的磁密分离的系统和方法。 所述系统（10）包括磁体（2），所述磁体被配置为放大磁性液体（L）中的密度梯度（D），用于根据磁性液体（L）的不同密度分离所述产品（1a，1b） ， D b）。 沿着产品路径（P）设置板形（3），各产品（1b'）穿过磁性液体（L）。 驱动机构（4）被构造成以往复运动（R）驱动板形状（3），以降低与板形状（3）接触的各个产品（1b“）的静摩擦。 因此，可以在保持高分离效率的同时提高过程连续性，特别是通过减轻材料在分离器和其他表面处的积聚和堵塞以及对过程流动的干扰最小。

公开(公告)号：WO2017027549A1

公开(公告)日：2017-02-16

申请号：PCT/US2016/046269

申请日：2016-08-10

申请人： DUKE UNIVERSITY

发明人： YELLEN, Benjamin B. ,  MURDOCH, David M. ,  ABEDINI-NASSAB, Roozbeh ,  WOOD, Kris C.

IPC分类号： B01L99/00 ,  B03C1/32 ,  G01N33/487

CPC分类号： B01L3/502761 ,  B01L2200/025 ,  B01L2200/0668 ,  B01L2200/147 ,  B01L2300/0816 ,  B01L2300/0851 ,  B01L2300/0864 ,  B01L2300/0883 ,  B01L2300/0893 ,  B01L2400/043 ,  B01L2400/0605 ,  B01L2400/0638 ,  B01L2400/0655 ,  B01L2400/0666 ,  B01L2400/0677 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26

摘要： The current invention relates to systems for transporting, trapping, and releasing magnetically-labeled bioparticles within microfluidic environments.

摘要翻译： 本发明涉及用于在微流体环境内运输，捕获和释放磁性标记的生物颗粒的系统。

公开(公告)号：WO2017004595A1

公开(公告)日：2017-01-05

申请号：PCT/US2016/040861

申请日：2016-07-01

申请人： ANCERA, INC.

发明人： KOSER, Hur

IPC分类号： B03C1/32 ,  G01N33/543 ,  G01N33/553

CPC分类号： G01N33/54333 ,  B03C1/023 ,  B03C1/0332 ,  B03C1/0335 ,  B03C1/288 ,  B03C1/32 ,  B03C2201/18 ,  B03C2201/26

摘要： Devices, methods, and systems are provided for extracting particles from a ferrofluid and for rapid affinity measurements. Such systems may comprise a fluidic channel or chamber configured to include a ferrofluid having a plurality of target particles and background particles. The systems may include a capture region configured to capture at least a portion of the plurality of target particles. In addition, the systems include a first magnetic field generator and a second magnetic field generator. The first magnetic field generator may be arranged proximate to the fluidic channel, the first magnetic field generator being configured to generate a first magnetic field configured to direct the plurality of target particles towards the capture region. The second magnetic field generator can be arranged to be proximate to the capture region, and is further configured to generate an affinity thresholding magnetic field configured to remove background particles from the capture region.

摘要翻译： 提供装置，方法和系统用于从铁磁流体中提取颗粒并用于快速亲和力测量。 这样的系统可以包括被配置为包括具有多个靶颗粒和背景颗粒的铁磁流体的流体通道或室。 该系统可以包括被配置为捕获多个目标粒子的至少一部分的捕获区域。 另外，该系统包括第一磁场发生器和第二磁场发生器。 第一磁场发生器可以布置成靠近流体通道，第一磁场发生器被配置为产生被配置为将多个目标粒子引向捕获区域的第一磁场。 第二磁场发生器可以布置成靠近捕获区域，并且还被配置为产生被配置为从捕获区域去除背景颗粒的亲和阈值磁场。

公开(公告)号：WO2016200900A1

公开(公告)日：2016-12-15

申请号：PCT/US2016/036393

申请日：2016-06-08

申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

发明人： VERMESH, Ophir ,  GAMBHIR, Sanjiv, Sam ,  PARK, Seung-min ,  GE, Tianjia, Jessie ,  AALIPOUR, Amin

IPC分类号： B03C1/32

CPC分类号： A61B17/52 ,  A61B5/05 ,  A61B5/14546 ,  A61B5/6851 ,  A61B10/04 ,  A61N2/06

摘要： A medical device and method for detection, retrieval or elimination of disease- associated toxins and biomarkers is provided. A plurality of magnets is arranged within a flexible sheath forming a flexible wire. The magnets are magnetically attached to each other, end-to-end, and arranged with their magnetic polarities alternating in direction. The magnetization direction of each of the magnets is orthogonal to the length axis of the flexible wire. The medical device is completely self-contained and does not require a bulky external field source able to maintain strong magnetic field gradients (100- 10,000 T/m) along the wire, and at a radial distance (~1 mm) to attract magnetic particles throughout the entire vein diameter at a range of physiologic velocities (1-10 cm/sec). This technology is a major step forward for the clinical relevance of CTC analysis to personalized medicine and introduces a powerful generalizable strategy for enrichment of other rare blood biomarkers.

摘要翻译： 提供了用于检测，检索或消除疾病相关毒素和生物标志物的医疗装置和方法。 多个磁体布置在形成柔性线的柔性护套内。 磁体彼此以磁性方式相互连接，端对端并以其极性在方向上交替排列。 每个磁体的磁化方向与柔性线的长度轴正交。 医疗器械是完全独立的，不需要庞大的外部场源，能够沿着电线和径向距离（〜1 mm）保持强磁场梯度（100 - 10,000 T / m），以吸引磁性颗粒 在整个静脉直径处的生理速度范围（1-10cm / sec）。 该技术是CTC分析与个性化医学临床相关性的重要一步，为其他稀有血液生物标志物的富集提供了强大的可推广的策略。

公开(公告)号：WO2016133379A4

公开(公告)日：2016-12-08

申请号：PCT/MX2016000013

申请日：2016-02-16

申请人： LÓPEZ VALDIVIESO ALEJANDRO ,  CORONA ARROYO MARIO ALBERTO ,  ENCINAS OROPESA ARMANDO ,  NAHMAD MOLINARI YURI

发明人： LÓPEZ VALDIVIESO ALEJANDRO ,  CORONA ARROYO MARIO ALBERTO ,  ENCINAS OROPESA ARMANDO ,  NAHMAD MOLINARI YURI

IPC分类号： B03C1/32

CPC分类号： B03C1/02

摘要： The invention relates to a novel device and process for enriching magnetic minerals (magnetite) by removing metal sulphides, silicates, phosphates and other unwanted particles, characterised by a device comprising a downflow pipe (mixer) and a separation column surrounded by Helmholtz coils. Pulp is fed into the mixer, in which air bubbles form in the presence of the pulp and bubble-particle collection processes are performed. The mixer discharges the pulp-bubble mixture into the separation column in a region that has a low magnetic field, less than 200 Gauss, which can be adjusted. Non-magnetic particles (gangue) are removed by the bubbles at the upper part of the column to form the tailings from the process, while magnetic particles sediment rapidly on the bottom of the column, from where they are removed to form the iron concentrate. As a result of the increase in the percentage of solids in the concentrate cone, most of the water that enters the device is discharged in the tailings, generating an upward flow of water which drags the gangue particles that were not captured by the bubbles. Using these mechanisms, the gangue is discharged in the tailings by two methods: flotation, and hydrodynamic drag. The magnetite forms aggregates of sufficient weight that they are not conveyed by the bubbles but sediment rapidly on the bottom of the column, allowing selective separation of magnetite and gangue.

摘要翻译： 本发明涉及一种用于通过去除金属硫化物，硅酸盐，磷酸盐和其它不想要的颗粒来富集磁性矿物（磁铁矿）的新型装置和方法，其特征在于包括下流管（混合器）和由亥姆霍兹线圈包围的分离柱的装置。 将纸浆进料到混合器中，其中在纸浆存在下形成气泡并进行气泡 - 颗粒收集过程。 混合器将纸浆 - 气泡混合物排出到具有小于200高斯的低磁场的区域中，该区域可被调节。 非磁性颗粒（脉石）通过柱上部的气泡除去，形成了该过程的尾矿，而磁性颗粒在柱底部迅速沉积，从中去除它们以形成铁精矿。 由于浓缩锥体中固体百分比的增加，进入设备的大部分水在尾矿中排出，产生向上的水流，该水流阻止未被气泡捕获的脉石颗粒。 使用这些机制，g石通过浮选和流体动力学阻力两种方式排放到尾矿中。 磁铁矿形成足够重量的聚集体，使其不被气泡输送，而在塔底部迅速沉淀，允许选择性分离磁铁矿和ang石。

公开(公告)号：WO2014158016A1

公开(公告)日：2014-10-02

申请号：PCT/NL2014/050177

申请日：2014-03-21

申请人： TECHNISCHE UNIVERSITEIT DELFT

发明人： POLINDER, Hendrik ,  REM, Peter Carlo

IPC分类号： B03C1/28 ,  B03C1/033 ,  B03C1/01 ,  B03C1/32 ,  B03B5/30 ,  B03B5/44 ,  H01F7/02

CPC分类号： B03C1/32 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/0335 ,  B03C1/288 ,  B03C2201/20 ,  H01F7/0231 ,  H01F7/0278

摘要： A planar magnet for magnetic density separation, comprising an array of pole pieces succeeding in longitudinal direction of a mounting plane, each pole piece having a body extending transversely along the mounting plane with a substantially constant cross section that includes a top segment that is curved to distribute the magnetic field associated with the top surface of the pole piece such that its strength transverse to the mounting plane is substantially uniformly distributed in planes parallel to the mounting plane, the curved top segments having a width (w) in longitudinal direction of the mounting plane and a maximum height (h) transverse to the mounting plane, wherein the top segments of successive pole pieces are unequal in height and/or width.

摘要翻译： 一种用于磁密度分离的平面磁体，包括在安装平面的纵向方向上的极片阵列，每个极片具有沿着安装平面横向延伸的主体，该主体具有基本恒定的横截面，该横截面包括顶部段， 分布与极靴的顶面相关联的磁场，使得其横穿于安装平面的强度基本均匀地分布在平行于安装平面的平面中，弯曲的顶部段在安装的纵向方向上具有宽度（w） 平面和横向于安装平面的最大高度（h），其中连续极片的顶部段的高度和/或宽度不相等。

公开(公告)号：WO2013148809A1

公开(公告)日：2013-10-03

申请号：PCT/US2013/034056

申请日：2013-03-27

申请人： RSR TECHNOLOGIES, INC.

发明人： ELLIS, Timothy, W. ,  MONTENEGRO, Joshua, A.

IPC分类号： B03C1/28 ,  B03C1/32 ,  H01M6/52 ,  H01M10/54

CPC分类号： B03C1/286 ,  B03C1/032 ,  B03C1/0335 ,  B03C1/034 ,  B03C1/32 ,  B03C2201/18 ,  B07B1/46 ,  B07B1/4609 ,  B07B1/4645 ,  H01M10/54 ,  Y02W30/84

摘要： A process and system for the separation of materials from electrochemical cells is disclosed. Electrode materials are removed from electrochemical cells and separated into constituent active materials using magnetic separation.

摘要翻译： 公开了一种用于从电化学电池分离材料的方法和系统。 从电化学电池中除去电极材料，并使用磁选分离成组分活性材料。