公开(公告)号：WO2010135447A3

公开(公告)日：2010-11-25

申请号：PCT/US2010/035436

申请日：2010-05-19

Applicant: ZINC MEDICAL, INC. ,  CADY, Timothy, B.

Inventor： CADY, Timothy, B.

IPC: A61L2/16 ,  A61M35/00

Abstract: Single-use devices configured to sanitize accessible surfaces of needleless medical valves at risk of contamination with infectious agents are described, as are methods for making and using such devices. Such devices include a sanitizing element securely attached to an inner surface of at least one of the two or more layers that make up the container inside of which the sanitizing element is stored until it is ready to be used. Examples of containers include laminated foil pouches or packets.

公开(公告)号：WO2010083589A1

公开(公告)日：2010-07-29

申请号：PCT/CA2010/000067

申请日：2010-01-22

Applicant: KANE BIOTECH INC. ,  GAWANDE, Purushottam ,  MADHYASTHA, Srinivasa ,  LOVETRI, Karen ,  YAKANDAWALA, Nandadeva ,  FROEHLICH, Gord

Inventor： GAWANDE, Purushottam ,  MADHYASTHA, Srinivasa ,  LOVETRI, Karen ,  YAKANDAWALA, Nandadeva ,  FROEHLICH, Gord

IPC: A01N63/02 ,  A01N33/12 ,  A01N43/54 ,  A01N47/44 ,  A01N59/12 ,  A01N59/16 ,  A01P1/00 ,  A01P3/00 ,  A61K31/09 ,  A61K31/155 ,  A61K31/513 ,  A61K33/18 ,  A61K33/38 ,  A61K38/10 ,  A61K38/16 ,  A61K38/17 ,  A61L2/16 ,  A61P31/02

CPC classification number: A61K31/14 ,  A01N59/12 ,  A01N59/16 ,  A01N63/02 ,  A61K8/20 ,  A61K8/416 ,  A61K8/43 ,  A61K8/4953 ,  A61K8/64 ,  A61K31/09 ,  A61K31/155 ,  A61K31/513 ,  A61K31/635 ,  A61K33/38 ,  A61K45/06 ,  A61L12/088 ,  A61Q17/005 ,  Y02A50/473 ,  A01N33/12 ,  A01N25/34 ,  A01N43/54 ,  A01N47/44 ,  A01N2300/00 ,  A61K2300/00

Abstract: The present invention provides novel compositions comprising: (a) protamine sulfate and (b) benzalkonium chloride or a silver containing particle; and (a) sodium metaperiodate and (b) 5-fluorouracil or chlorhexidine and uses thereof for the preparation of devices, and in particular medical devices, susceptible to colonization by biofilm forming bacteria.

Abstract translation: 本发明提供新的组合物，其包含：（a）硫酸鱼精蛋白和（b）苯扎氯铵或含银颗粒; 和（a）偏高碘酸钠和（b）5-氟尿嘧啶或氯己定及其用于制备容易被生物膜形成细菌定植的装置，特别是医疗装置的用途。

公开(公告)号：WO2010046142A3

公开(公告)日：2010-04-29

申请号：PCT/EP2009/054848

申请日：2009-04-22

Applicant: GETINGE DISINFECTION AB ,  NOVOZYMES A/S ,  JOHANSSON, Jonas ,  CHRISTENSEN, Bjoern Eggert ,  ALLESEN-HOLM, Marie ,  DANIELSEN, Steffen ,  GJERMANSEN, Morten

Inventor： JOHANSSON, Jonas ,  CHRISTENSEN, Bjoern Eggert ,  ALLESEN-HOLM, Marie ,  DANIELSEN, Steffen ,  GJERMANSEN, Morten

IPC: A01N63/00 ,  A01N63/04 ,  A01N59/00 ,  A01P1/00 ,  C11D3/386 ,  C12N9/08 ,  A61L2/16 ,  A47L15/44 ,  A61L2/00 ,  A61L2/24

Abstract: A washer disinfector (1 ) for disinfecting or sterilizing a device (D), comprises a washing chamber (2) which is adapted for housing said device (D), and an arrangement (34, 36, 38, 40, 42, 44) for supplying a haloperoxidase, hydrogen peroxide, chloride and/or bromide ions, and ammonium ions to said washing chamber (2). A method of disinfecting or sterilizing a device (D) in a washer disinfector (1 ) comprises supplying a haloperoxidase, hydrogen peroxide, chloride and/or bromide ions, and ammonium ions to the washer-disinfector (1 ).

公开(公告)号：WO2010017633A1

公开(公告)日：2010-02-18

申请号：PCT/CA2009/001126

申请日：2009-08-12

Applicant: MILLER, Chris ,  MURRAY, Bruce ,  REGEV-SHOSHANI, Gilly

Inventor： MILLER, Chris ,  MURRAY, Bruce ,  REGEV-SHOSHANI, Gilly

IPC: A61K33/00 ,  A01N25/02 ,  A01N59/00 ,  A01P1/00 ,  A61L2/16 ,  A61L9/00 ,  A61P31/12 ,  A61P31/16 ,  A62B18/02 ,  A62B23/02 ,  A62B23/06 ,  A62B7/10 ,  B01D37/02 ,  B65D83/14 ,  F24F3/16

CPC classification number: A61K33/00 ,  A01N59/00 ,  A62B23/025 ,  A01N25/34

Abstract: The present invention relates to uses, compositions, devices, and methods involving the utilisation of nitric oxide to hinder, impede, inhibit, or prevent transmission of infectious viral particles to host cells.

Abstract translation: 本发明涉及涉及利用一氧化氮阻碍，阻止，抑制或预防感染性病毒颗粒向宿主细胞传播的用途，组合物，装置和方法。

公开(公告)号：WO2008087639A3

公开(公告)日：2010-01-28

申请号：PCT/IL2008000069

申请日：2008-01-16

Applicant: FORSCHNER ITAY

Inventor： FORSCHNER ITAY

IPC: A61L2/16

CPC classification number: A61B50/362

Abstract: A device for retaining sharps includes a sharps retaining block made of a viscid material. The block has an adjacent layer made from material that presents greater resistance than the resistance of the viscid material to penetration by the sharps, and is located substantially opposite a surface of the sharps retaining block designated for sharps insertion. The device also includes at least one elongated handle extending from the sharps retaining block.

Abstract translation: 用于保持尖锐的装置包括由粘性材料制成的锐利物保持块。 该块具有由材料制成的相邻层，其具有比粘性材料对尖锐物穿透的阻力更大的阻力，并且与被指定用于锐利插入的锐利物保持块的表面基本相对。 该装置还包括从锐利物保持块延伸的至少一个细长手柄。

公开(公告)号：WO2009088875A3

公开(公告)日：2009-11-19

申请号：PCT/US2008088562

申请日：2008-12-30

Applicant: MIOX CORPORTION ,  KUHLMANN KURT ,  MATTHEWS DAN ,  SANCHEZ JUSTIN ,  HERRINGTON RODNEY E

Inventor： KUHLMANN KURT ,  MATTHEWS DAN ,  SANCHEZ JUSTIN ,  HERRINGTON RODNEY E

IPC: A61L2/16 ,  A61L2/08

CPC classification number: C02F1/46104 ,  C02F1/002 ,  C02F1/4674 ,  C02F2201/46165 ,  C02F2209/008 ,  C02F2209/05 ,  C02F2303/04

Abstract: An electrolytic device and method for generating a disinfecting solution that utilizes an electrical circuit and storage battery. The electrical circuit preferably conditions the power received from a variety of power sources to charge the storage battery and conditions the power stored in the storage battery to provide the appropriate power to maximize the disinfection efficacy of the disinfecting solution. The device may incorporate one or more other devices such as an LED, an electrical power takeoff, a clock, a compass, a transmitter device, a receiver device, a position locating device, a direction indicating device, and/or a camera.

Abstract translation: 一种用于产生利用电路和蓄电池的消毒溶液的电解装置和方法。 电路优选地调节从各种电源接收的功率以对蓄电池充电并且调节存储在蓄电池中的功率以提供适当的功率以最大化消毒溶液的消毒功效。 该装置可以包括一个或多个其他装置，例如LED，电功率输出，时钟，罗盘，发射器装置，接收器装置，位置定位装置，方向指示装置和/或照相机。

公开(公告)号：WO2009130599A2

公开(公告)日：2009-10-29

申请号：PCT/IB2009/005715

申请日：2009-04-17

Applicant: 1099309 ONTARIO LTD. D/B/A ARMALAC INDUSTRIES ,  BOWER, Raymond, Patrick Charles

Inventor： BOWER, Raymond, Patrick Charles

IPC: C09D193/02 ,  C09B61/00 ,  A61L2/16

CPC classification number: A61L2/16 ,  A61K8/987 ,  A61Q19/00 ,  C09D193/02

Abstract: Bleached shellac and methods for producing the bleached shellac are disclosed. The bleached shellac comprises reduced salts, reduced water soluble and water insoluble contaminants, reduced microbial contamination, enhanced shelf life, enhanced hardness, and enhanced scratchability. Coatings comprising a bleached shellac of the disclosure and coated substrates comprising said coatings are also disclosed.

Abstract translation: 公开了漂白的紫胶和用于生产漂白的紫胶的方法。 漂白的紫胶包括减少的盐，减少的水溶性和水不溶性污染物，减少的微生物污染，增加的保质期，增强的硬度和增强的可擦性。 还公开了包含本公开的漂白紫胶和包含所述涂层的涂覆基材的涂料。

公开(公告)号：WO2009012162A3

公开(公告)日：2009-03-19

申请号：PCT/US2008069827

申请日：2008-07-11

Applicant: ALLVIVO VASCULAR INC ,  OREGON STATE ,  NEFF JENNIFER A ,  JOSHI PRANAV R ,  MCGUIRE JOSEPH

Inventor： NEFF JENNIFER A ,  JOSHI PRANAV R ,  MCGUIRE JOSEPH

IPC: A01N25/10 ,  A61L2/16 ,  C08G65/32 ,  C08K13/08

CPC classification number: A01N25/10 ,  A01N25/34 ,  A01N63/02 ,  A23L3/3463 ,  A61K47/48215 ,  A61K47/48992 ,  A61K47/60 ,  A61K47/6957 ,  A61L2/232 ,  C08G65/3348 ,  C08G2650/58 ,  C08K9/08 ,  C08K2201/013 ,  C08L71/02 ,  C08L2205/05 ,  Y10T428/1352 ,  Y10T428/1376 ,  A01N43/90 ,  A01N2300/00 ,  C08L2666/02 ,  A01N37/46

Abstract: The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC? F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped peptide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.

Abstract translation: 本发明基于这样的认识：已知的抗微生物化合物，如乳链菌肽或其他羊毛硫抗生素，可通过将肽与嵌段聚合物如PLURONIC？连接而形成长效抗菌表面涂层， F108或端基活化的聚合物（EGAP）以形成柔性系链和/或截留肽的方式。 包埋的肽通过早期从包埋中释放而提供抗微生物作用，而连接的肽提供更持久的抗微生物保护。 可以使用含有抗微生物肽的嵌段共聚物制备抗微生物凝胶和泡沫。

公开(公告)号：WO2009030040A1

公开(公告)日：2009-03-12

申请号：PCT/CA2008/001576

申请日：2008-09-04

Applicant: INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  LACROIX, Monique ,  MILLETTE, Mathieu

Inventor： LACROIX, Monique ,  MILLETTE, Mathieu

IPC: C12N1/20 ,  A01N63/00 ,  A23L1/30 ,  A23L3/3463 ,  A23L3/3526 ,  A23L3/3571 ,  A61K35/74 ,  A61K38/16 ,  A61L2/16 ,  A61P31/04 ,  C07K14/195 ,  C12P21/02 ,  C07K14/335 ,  C12N15/31

CPC classification number: A23K10/18 ,  A01N63/00 ,  A01N63/02 ,  A23L3/34635 ,  A23L3/3571 ,  A23L33/135 ,  A61K35/744 ,  C07K14/335 ,  C12P21/02 ,  C12R1/01 ,  C12R1/46

Abstract: The present invention relates to novel bacteriocin-producing lactic acid bacteria strains Lactococcus lactis subsp. lactis MM19 accession number NML-080508-01and Pediococcus acidilactici MM33 accession number NML-080508-02 isolated from the human gut. The strains L. lactis subsp. l actis MM19 and P. acidilactici MM33 and the bacteriocins produced by these strains are useful for inhibiting microbial growth in food products, and for inhibiting microbial infection or colonization of a mammal.

Abstract translation: 本发明涉及新生的产生细菌素的乳酸菌菌株乳酸乳球菌 乳酸菌MM19登录号NML-080508-01和洋葱球菌MM33登录号NML-080508-02从人类肠道中分离。 乳酸乳杆菌亚种 乳酸菌MM19和尿酸乳杆菌MM33以及这些菌株产生的细菌素可用于抑制食品中的微生物生长，以及抑制哺乳动物的微生物感染或定植。

公开(公告)号：WO2008132719A2

公开(公告)日：2008-11-06

申请号：PCT/IL2008000468

申请日：2008-04-03

Applicant: SURE INTERNAT VENTURES B V ,  BUKSHPAN SHMUEL ,  ZILBERSTEIN GLEB

Inventor： BUKSHPAN SHMUEL ,  ZILBERSTEIN GLEB

IPC: A01N61/00 ,  A01N25/10 ,  A01N25/34 ,  A01P1/00 ,  A23L3/00 ,  A61K8/00 ,  A61L2/16 ,  B65B55/00

CPC classification number: A61L2/16 ,  A01N25/34 ,  A01N37/08 ,  A01N37/20 ,  A01N41/04 ,  A01N61/00 ,  A23L3/3463

Abstract: The present invention presents a biocidic packaging for cosmetics and/or foodstuffs, comprises at least one insoluble proton sink or source (PSS). The ackaging is provided useful for killing living target cells (LTCs), or otherwise disrupting vital intracellular processes and/or intercellular interactions of said LTC upon contact. The PSS comprises, inter alia, (i) proton source or sink providing a buffering capacity; and (ii) means providing proton conductivity and/or electrical potential. The PSS is effectively disrupting the pH homeostasis and/or electrical balance within the confined volume of the LTC and/or disrupting vital intercellular interactions of the LTCs while efficiently preserving the pH of said LTCs' environment. The present invention also discloses a method for killing living target cells (LTCs), or otherwise disrupting vital intracellular processes and/or intercellular interactions of said LTC being in a packaging, especially cosmetic or foodstuffs' packaging.

Abstract translation: 本发明提出了一种用于化妆品和/或食品的生物杀伤剂包装，包括至少一种不溶性质子沉或源（PSS）。 提供了用于杀死活的靶细胞（LTC）或另外破坏所述LTC在接触时的重要的细胞内过程和/或细胞间相互作用的有效性。 PSS尤其包括（i）提供缓冲能力的质子源或接收器; 和（ii）提供质子传导性和/或电势的手段。 PSS有效地破坏LTC的限制体积内的pH稳态和/或电气平衡和/或破坏LTC的重要的细胞间相互作用，同时有效地保持所述LTC的环境的pH。 本发明还公开了一种用于杀死活的靶细胞（LTC）或以其它方式破坏所述LTC在包装，特别是化妆品或食品包装中的细胞内过程和/或细胞间相互作用的方法。