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    ERGOT DERIVATIVE COMPOUNDS AND THEIR USE IN AFRICAN SLEEPING SICKNESS AND RELATED DISEASE
    6.
    发明申请
    ERGOT DERIVATIVE COMPOUNDS AND THEIR USE IN AFRICAN SLEEPING SICKNESS AND RELATED DISEASE 审中-公开
    ERGOT衍生物化合物及其在非洲睡眠疾病和相关疾病中的应用

    公开(公告)号：WO2018076019A1

    公开(公告)日：2018-04-26

    申请号：PCT/US2017/057917

    申请日：2017-10-23

    Applicant: FAR BIOTECH, INC.

    Inventor： MARTINOV, Martin, N.

    IPC: A61K31/48 ,  C07D457/02 ,  C07D457/06

    CPC classification number: C07D457/02 ,  A61K31/48 ,  A61K45/06 ,  A61K2300/00

    Abstract: A novel quantum-based computational process for drug discovery and design was used to identify potential novel liver-stage anti-malarial therapeutic molecules. The approach combined the latest big-data advances in high-throughput bioassay development with fundamental scientific knowledge to generate new pharmaceutical leads. Several indoloquinolines molecules, including nicergoline and structurally related molecules, with no previous association with anti- parasitical activity were identified. These molecules and there use in prevention and/or treatment of Trypanosoma infections are provided.

    Abstract translation: 用于药物发现和设计的新的基于量子的计算过程用于鉴定潜在的新型肝脏阶段抗疟疾治疗分子。 该方法将高通量生物测定开发的最新大数据进展与基础科学知识相结合，以产生新的制药线索。 鉴定了几种吲哚喹啉分子，包括尼麦角林和结构相关分子，以前没有与抗寄生虫活性相关联。 提供这些分子并用于预防和/或治疗锥虫感染。

    UNMANNED OR OPTIONALLY MANNED VEHICLE, SYSTEM AND METHODS FOR DETERMINING POSITIONAL INFORMATION OF UNMANNED OR OPTIONALLY MANNED VEHICLES
    7.
    发明申请
    UNMANNED OR OPTIONALLY MANNED VEHICLE, SYSTEM AND METHODS FOR DETERMINING POSITIONAL INFORMATION OF UNMANNED OR OPTIONALLY MANNED VEHICLES 审中-公开
    无人驾驶或特定方式驾驶的车辆，系统和方法，用于确定无人驾驶或可选方向驾驶的车辆的位置信息

    公开(公告)号：WO2017189070A3

    公开(公告)日：2017-11-02

    申请号：PCT/US2017/016266

    申请日：2017-02-02

    Applicant: PROXY TECHNOLOGIES, INC.

    Inventor： KLINGER, John ,  CESARANO, Patrick, C.

    IPC: G05D1/00 ,  G05D1/02

    Abstract: Some embodiments are directed to an unmanned vehicle for use with a companion unmanned vehicle. The unmanned vehicle includes a location unit that is configured to determine a current position of the unmanned vehicle. The unmanned vehicle includes a path planning unit that generates a planned path. The unmanned vehicle receives a planned path of the companion unmanned vehicle and a current position of the companion unmanned vehicle. The unmanned vehicle includes a position unit that is configured to determine a relative position between the unmanned vehicle and the companion unmanned vehicle based on at least the planned paths and the current positions of the unmanned vehicle and the companion unmanned vehicle. The unmanned vehicle also includes a control unit that is configured to control a movement of the unmanned vehicle based on at least the relative position between the unmanned vehicle and the companion unmanned vehicle.

    Abstract translation: 一些实施例针对用于伴随无人驾驶车辆的无人驾驶车辆。 无人驾驶车辆包括被配置为确定无人驾驶车辆的当前位置的定位单元。 无人驾驶车辆包括生成规划路径的路径规划单元。 无人驾驶车辆接收伴随无人驾驶车辆的规划路线和伴随无人驾驶车辆的当前位置。 无人驾驶车辆包括位置单元，该位置单元被配置为至少基于无人驾驶车辆和伴随无人驾驶车辆的规划路径和当前位置来确定无人驾驶车辆和伴随无人驾驶车辆之间的相对位置。 无人驾驶车辆还包括控制单元，该控制单元被配置成至少基于无人驾驶车辆和伴随无人驾驶车辆之间的相对位置来控制无人驾驶车辆的移动。

    ELECTRONIC ASSESSMENTS, AND METHODS OF USE AND MANUFACTURE THEREOF
    8.
    发明申请
    ELECTRONIC ASSESSMENTS, AND METHODS OF USE AND MANUFACTURE THEREOF 审中-公开

    公开(公告)号：WO2017172039A3

    公开(公告)日：2017-10-05

    申请号：PCT/US2017/016261

    申请日：2017-02-02

    Applicant: PROXY TECHNOLOGIES, INC.

    Inventor： CESARANO, Patrick, C.

    IPC: G06K9/00 ,  G06K9/62 ,  G05D1/00

    Abstract: The disclosed subject matter relates to methods and apparatus facilitating assessments of structural and electronic features, parameters, characteristics or any combination thereof using one or more unmanned autonomous vehicles. In some embodiments, an unmanned vehicle may be configured to monitor one or both of the structural and electrical characteristics of an object, and can also include cooperative behavior between two or more unmanned vehicles to test electrical communication in a directional fashion.

    VEHICLE, SYSTEM AND METHODS FOR DETERMINING AUTOPILOT PARAMETERS IN A VEHICLE
    9.
    发明申请
    VEHICLE, SYSTEM AND METHODS FOR DETERMINING AUTOPILOT PARAMETERS IN A VEHICLE 审中-公开

    公开(公告)号：WO2017164993A3

    公开(公告)日：2017-09-28

    申请号：PCT/US2017/016287

    申请日：2017-02-02

    Applicant: PROXY TECHNOLOGIES, INC.

    Inventor： KLINGER, John ,  ANDREWS, Bruce ,  CESARANO, Patrick, C.

    IPC: G05D1/00 ,  G05D1/02

    Abstract: Some embodiments are directed to a system for use with a vehicle, the system including control circuits for controlling an operation of the vehicle, each of the control circuits implementing autopilot coefficients. The system further includes a sensor that is configured to detect control circuits operating in an untuned or incorrectly tuned state from the control circuits; an electronic switch that is configured to isolate the control circuits in the untuned or incorrectly tuned state from other control circuits; a tuning circuit that is configured to determine tuned values of the autopilot coefficients corresponding to the control circuits in the untuned or incorrectly tuned state; the tuned values of the autopilot coefficients enabling the control circuits to operate in a tuned state; and a memory to store the tuned values of the autopilot coefficients, wherein the electronic switch is further configured to connect the control circuits in the tuned state to the other control circuits.

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