公开(公告)号：WO2011053845A3

公开(公告)日：2011-09-22

申请号：PCT/US2010054829

申请日：2010-10-29

Applicant: ILLUMINA INC ,  MOON JOHN A ,  BOWEN M SHANE ,  SMITH RYAN C ,  PERBOST MICHEL ,  LEBL MICHAL ,  MODIANO STEVEN H

Inventor： MOON JOHN A ,  BOWEN M SHANE ,  SMITH RYAN C ,  PERBOST MICHEL ,  LEBL MICHAL ,  MODIANO STEVEN H

IPC: G01N33/50 ,  C12Q1/68 ,  G01N21/84 ,  G01N33/52

CPC classification number: G01N33/50 ,  B01J19/0046 ,  B01J2219/00306 ,  B01J2219/00511 ,  B01J2219/0052 ,  B01J2219/00524 ,  B01J2219/00545 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00673 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01L3/502761 ,  B01L3/5082 ,  B01L3/50857 ,  B01L3/5088 ,  B01L3/545 ,  C40B20/04 ,  G01N21/01 ,  G01N21/253 ,  G01N21/6452 ,  G01N35/00732

Abstract: A method of reading a plurality of encoded microvessels used in an assay for biological or chemical analysis The method can include providing a plurality of encoded microvessels The microvessels can include a respective microbody and a reservoir core configured to hold a substance in the reservoir core The microbody can include a material that surrounds the reservoir core and facilitates detection of a characteristic of the substance within the reservoir core Optionally, the material can be transparent so as to facilitate detection of an optical characteristic of a substance within the reservoir core The microbody can include an identifiable code associated with the substance The method can also include determining the corresponding codes of the microvessels.

Abstract translation: 读取用于生物或化学分析的测定中使用的多个编码的微血管的方法该方法可以包括提供多个编码的微血管。微血管可以包括相应的微体和构造成将物质保持在储存器核心中的储存器芯。微体 可以包括围绕贮存器芯体的材料并且便于检测贮存器芯体内的物质的特性。可选地，该材料可以是透明的，以便于检测贮存器芯体内的物质的光学特性。微体可以包括 与物质相关的可识别代码该方法还可以包括确定微血管的相应代码。

公开(公告)号：WO2011053845A2

公开(公告)日：2011-05-05

申请号：PCT/US2010/054829

申请日：2010-10-29

Applicant: ILLUMINA, INC. ,  MOON, John, A. ,  BOWEN, M., Shane ,  SMITH, Ryan, C. ,  PERBOST, Michel ,  LEBL, Michal ,  MODIANO, Steven, H.

Inventor： MOON, John, A. ,  BOWEN, M., Shane ,  SMITH, Ryan, C. ,  PERBOST, Michel ,  LEBL, Michal ,  MODIANO, Steven, H.

IPC: G01N33/50 ,  C12Q1/68 ,  G01N33/52 ,  G01N21/84

CPC classification number: G01N33/50 ,  B01J19/0046 ,  B01J2219/00306 ,  B01J2219/00511 ,  B01J2219/0052 ,  B01J2219/00524 ,  B01J2219/00545 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00673 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01L3/502761 ,  B01L3/5082 ,  B01L3/50857 ,  B01L3/5088 ,  B01L3/545 ,  C40B20/04 ,  G01N21/01 ,  G01N21/253 ,  G01N21/6452 ,  G01N35/00732

Abstract: A method of reading a plurality of encoded microvessels used in an assay for biological or chemical analysis The method can include providing a plurality of encoded microvessels The microvessels can include a respective microbody and a reservoir core configured to hold a substance in the reservoir core The microbody can include a material that surrounds the reservoir core and facilitates detection of a characteristic of the substance within the reservoir core Optionally, the material can be transparent so as to facilitate detection of an optical characteristic of a substance within the reservoir core The microbody can include an identifiable code associated with the substance The method can also include determining the corresponding codes of the microvessels.

Abstract translation: 读取用于生物或化学分析的测定中的多个编码的微血管的方法该方法可以包括提供多个编码的微血管。微血管可以包括相应的微体和被配置为将物质保持在储存器芯中的储存器芯。微体 可以包括围绕储存器芯的材料，并且便于检测储存器芯内的物质的特性。可选地，材料可以是透明的，以便于检测储存器芯内的物质的光学特性微体可以包括 与物质相关的可识别代码该方法还可以包括确定微血管的相应代码。

公开(公告)号：WO2013063382A3

公开(公告)日：2013-10-10

申请号：PCT/US2012062105

申请日：2012-10-26

Applicant: ILLUMINA INC ,  BOWEN M SHANE ,  GUNDERSON KEVIN L ,  LIN SHENGRONG ,  BACIGALUPO MARIA CANDELARIA ROGERT ,  VIJAYAN KANDASWAMY ,  WU YIR-SHYUAN ,  VENKATESAN BALA MURALI ,  TSAY JAMES ,  BEIERLE JOHN M ,  BERTI LORENZO ,  PARK SANG RYUL

Inventor： BOWEN M SHANE ,  GUNDERSON KEVIN L ,  LIN SHENGRONG ,  BACIGALUPO MARIA CANDELARIA ROGERT ,  VIJAYAN KANDASWAMY ,  WU YIR-SHYUAN ,  VENKATESAN BALA MURALI ,  TSAY JAMES ,  BEIERLE JOHN M ,  BERTI LORENZO ,  PARK SANG RYUL

IPC: B01J19/00 ,  C12Q1/68 ,  G01N33/543

CPC classification number: C12Q1/6844 ,  B01J19/0046 ,  B01J2219/00529 ,  B01J2219/00608 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00648 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01J2219/00722 ,  B01J2219/00788 ,  C12Q1/686 ,  C40B50/18 ,  C12Q2527/125 ,  C12Q2535/122 ,  C12Q2565/543

Abstract: A microarray is designed capture one or more molecules of interest at each of a plurality of sites on a substrate. The sites comprise base pads, such as polymer base pads, that promote the attachment of the molecules at the sites. The microarray may be made by one or more patterning techniques to create a layout of base pads in a desired pattern. Further, the microarrays may include features to encourage clonality at the sites.

Abstract translation: 微阵列被设计为在基底上的多个位点中的每一个处捕获一个或多个感兴趣的分子。 这些位点包含基垫，例如聚合物基垫，其促进分子在该位点处的附着。 微阵列可以通过一种或多种图案化技术制成，以便以期望的图案形成基垫的布局。 此外，微阵列可以包括鼓励在该位点克隆的特征。