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公开(公告)号：WO2007117564A2
公开(公告)日：2007-10-18
申请号：PCT/US2007/008526
申请日：2007-04-05
Applicant: E. I. DU PONT DE NEMOURS AND COMPANY , ITTEL, Steven, Dale , CUNNINGHAM, Scott, D. , ROUVIERE, Pierre, E. , FAHNESTOCK, Stephen, R. , O'BRIEN, John, P.
Inventor： ITTEL, Steven, Dale , CUNNINGHAM, Scott, D. , ROUVIERE, Pierre, E. , FAHNESTOCK, Stephen, R. , O'BRIEN, John, P.
CPC classification number: C07K7/06 , C07K7/08 , C07K14/001 , C07K17/14
Abstract: Combinatorially generated peptides are provided that have binding affinity for clay. The peptides may be used to deliver benefit agents to various clay surfaces.
Abstract translation: 提供了对粘土具有结合亲和力的组合产生的肽。 肽可以用于将有益剂递送到各种粘土表面。
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公开(公告)号：WO2012087968A2
公开(公告)日：2012-06-28
申请号：PCT/US2011/065908
申请日：2011-12-19
Applicant: E. I. DU PONT DE NEMOURS AND COMPANY , CHISHOLM, Dexter, A. , CUI, Xiumin , CUNNINGHAM, Scott, D. , DICOSIMO, Robert , FAHNESTOCK, Stephen, R. , GRUBER, Tanja, Maria , HUANG, Yongqing , JIANG, Xueping , PARTHASARATHY, Anju , PAYNE, Mark, S. , ROUVIERE, Pierre, E. , WANG, Hong
Inventor： CHISHOLM, Dexter, A. , CUI, Xiumin , CUNNINGHAM, Scott, D. , DICOSIMO, Robert , FAHNESTOCK, Stephen, R. , GRUBER, Tanja, Maria , HUANG, Yongqing , JIANG, Xueping , PARTHASARATHY, Anju , PAYNE, Mark, S. , ROUVIERE, Pierre, E. , WANG, Hong
CPC classification number: A61K8/66 , A61K8/22 , A61K8/38 , A61K8/64 , A61K38/46 , A61K38/465 , A61Q5/08 , A61Q5/10 , A61Q9/04 , A61Q15/00 , A61Q19/00 , A61Q19/02
Abstract: Disclosed herein are compositions and methods to treat hair with a peracid-based benefit agent. The peracid benefit agent can be used for hair bleaching, hair weakening, hair removal, hair waiving, hair straightening or any combination thereof. The peracid may be enzymatically generated from a carboxylic acid ester substrate using an enzyme having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a hair-binding domain, either directly or through an optional linker, may be used to target the perhydrolytic activity to the hair surface.
Abstract translation: 本文公开了用基于过酸的有益试剂治疗毛发的组合物和方法。 过酸有益剂可用于头发漂白，头发削弱，脱毛，脱毛，头发矫直或其任何组合。 在过氧源的存在下，可以使用具有过水解活性的酶（过水解酶），由羧酸酯底物酶促产生过酸。 包含直接或通过任选的接头与毛发结合结构域偶联的过水解酶的融合蛋白可用于将头发表面的水解活性靶向。
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公开(公告)号：WO2012087970A3
公开(公告)日：2012-11-22
申请号：PCT/US2011065912
申请日：2011-12-19
Applicant: DU PONT , BUTTERICK LISA A , CUNNINGHAM SCOTT D , DICOSIMO ROBERT , FOSSER KARI A , GRUBER TANJA MARIA , HAYNIE SHARON L , PAYNE MARK S , ROUVIERE PIERRE E , WANG HONG
Inventor： BUTTERICK LISA A , CUNNINGHAM SCOTT D , DICOSIMO ROBERT , FOSSER KARI A , GRUBER TANJA MARIA , HAYNIE SHARON L , PAYNE MARK S , ROUVIERE PIERRE E , WANG HONG
Abstract: Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.
Abstract translation: 本文公开了用基于过酸的有益试剂治疗口腔表面的组合物和方法。 过酸有益剂可用于口腔表面漂白，美白，消毒，脱色，除臭，减少或去除生物膜及其组合。 在过氧源的存在下，使用具有过水解活性的CE-7碳水化合物酯酶（过水解酶），由羧酸酯底物酶促产生过酸。 包含与直接或通过任选的接头对口腔表面具有亲和力的肽成分偶联的过水解酶的融合蛋白可用于将过水解活性靶向口腔表面。
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公开(公告)号：WO2010117709A2
公开(公告)日：2010-10-14
申请号：PCT/US2010/029016
申请日：2010-03-29
Applicant: JOHNSON & JOHNSON , E.I. DU PONT DE NEMOURS AND COMPANY , ANTON, Douglas, Robert , DALY, Susan , BIANCHINI, Robert, J. , WANG, Hong , ROUVIERE, Pierre, E. , CUNNINGHAM, Scott, D. , FAHNESTOCK, Stephen, R. , GRUBER, Tanja, Maria
Inventor： ANTON, Douglas, Robert , DALY, Susan , BIANCHINI, Robert, J. , WANG, Hong , ROUVIERE, Pierre, E. , CUNNINGHAM, Scott, D. , FAHNESTOCK, Stephen, R. , GRUBER, Tanja, Maria
IPC: A61Q5/06
CPC classification number: A61K8/64 , A61K8/19 , A61K2800/88 , A61K2800/884 , A61K2800/94 , A61Q5/10
Abstract: The present invention relates to compositions and systems comprising peptide-based reagents for delivery of cosmetic benefit agents to human hair, human skin, or human nail.
Abstract translation: 本发明涉及包含用于向人类头发，人类皮肤或人类指甲递送化妆品有益剂的基于肽的试剂的组合物和系统。
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公开(公告)号：WO2010114638A1
公开(公告)日：2010-10-07
申请号：PCT/US2010/022804
申请日：2010-02-02
Applicant: E. I. DU PONT DE NEMOURS AND COMPANY , ANTON, Douglas, Robert , CUNNINGHAM, Scott, D. , FAHNESTOCK, Stephen, R. , FOSSER, Kari, A. , WANG, Hong
Inventor： ANTON, Douglas, Robert , CUNNINGHAM, Scott, D. , FAHNESTOCK, Stephen, R. , FOSSER, Kari, A. , WANG, Hong
CPC classification number: A61K8/25 , A61K8/0241 , A61K8/29 , A61K8/64 , A61K8/731 , A61K2800/412 , A61K2800/43 , A61K2800/614 , A61Q11/00 , C07K7/08 , C07K14/001
Abstract: Peptide-based reagents comprising at least one tooth surface-binding peptide for delivery of at least one polymer coated white colorant to the surface of teeth are provided. The peptide-based reagent may comprise at least one tooth-binding peptide coupled to, either directly or through one or more spacers, a polymer-binding peptide capable of binding to the polymeric coating on a polymer-coated white colorant. Methods of delivering a polymer-coated white colorant to a tooth surface are also provided as well as oral care compositions comprising the present peptide-based reagents. The peptide-based reagents may be used in conjunction with at least one polymer-coated white colorant to improve the cosmetic appearance of teeth.
Abstract translation: 提供了包含用于将至少一种聚合物涂覆的白色着色剂递送到牙齿表面的至少一个牙齿表面结合肽的基于肽的试剂。 基于肽的试剂可以包含至少一种与粘合到聚合物涂覆的白色着色剂上的与聚合物涂层结合的聚合物结合肽直接或通过一个或多个间隔物偶联的牙结合肽。 还提供将聚合物涂覆的白色着色剂递送到牙齿表面的方法以及包含本发明的基于肽的试剂的口腔护理组合物。 基于肽的试剂可以与至少一种聚合物涂覆的白色着色剂结合使用以改善牙齿的美容外观。
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Patent Agency Ranking
公开(公告)号：WO2007117564A3
公开(公告)日：2008-02-07
申请号：PCT/US2007008526
申请日：2007-04-05
Applicant: DU PONT , ITTEL STEVEN DALE , CUNNINGHAM SCOTT D , ROUVIERE PIERRE E , FAHNESTOCK STEPHEN R , O'BRIEN JOHN P
Inventor： ITTEL STEVEN DALE , CUNNINGHAM SCOTT D , ROUVIERE PIERRE E , FAHNESTOCK STEPHEN R , O'BRIEN JOHN P
CPC classification number: C07K7/06 , C07K7/08 , C07K14/001 , C07K17/14
Abstract: Combinatorially generated peptides are provided that have binding affinity for clay. The peptides may be used to deliver benefit agents to various clay surfaces.
Abstract translation: 提供了对粘土具有结合亲和力的组合产生的肽。 肽可以用于将有益剂递送到各种粘土表面。
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公开(公告)号：WO2012087966A3
公开(公告)日：2013-01-17
申请号：PCT/US2011065902
申请日：2011-12-19
Applicant: DU PONT , DICOSIMO ROBERT , CUNNINGHAM SCOTT D , FAHNESTOCK STEPHEN R , GRUBER TANJA MARIA , PAYNE MARK S , ROUVIERE PIERRE E , SOLOMON LINDA JANE , WANG HONG
Inventor： DICOSIMO ROBERT , CUNNINGHAM SCOTT D , FAHNESTOCK STEPHEN R , GRUBER TANJA MARIA , PAYNE MARK S , ROUVIERE PIERRE E , SOLOMON LINDA JANE , WANG HONG
CPC classification number: C12N9/18 , C07K16/16 , C07K19/00 , C07K2319/01 , C11D3/38636 , C11D3/38681 , C12N9/14 , C12N9/2437 , C12P7/40 , C12P7/54
Abstract: Disclosed herein are compositions and methods to target enzymatic peracid production to a target surface. The peracid benefit agent produced by the targeted perhydrolytic enzyme can be use for a variety of applications such as bleaching, whitening, disinfecting, destaining, deodorizing, and combinations thereof. Specifically, a fusion protein comprising a perhydrolytic enzyme and at least one peptidic component having affinity for a target surface (excluding body surfaces and oral care surfaces) is used in combination with a suitable substrate and a source of peroxygen to enzymatically produce a peracid on or near the surface of the target material. In a preferred aspect, the target surface is a cellulosic material.
Abstract translation: 本文公开了将酶过氧酸生产靶向靶表面的组合物和方法。 由靶向的水解酶产生的过酸有益剂可用于各种应用，例如漂白，增白，消毒，脱色，除臭及其组合。 特别地，包含过水解酶和至少一种对靶表面（不包括体表和口腔护理表面）具有亲和力的肽组分的融合蛋白与合适的底物和过氧源组合使用以在 靠近目标材料的表面。 在优选的方面，目标表面是纤维素材料。
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公开(公告)号：WO2012087968A3
公开(公告)日：2012-11-22
申请号：PCT/US2011065908
申请日：2011-12-19
Applicant: DU PONT , CHISHOLM DEXTER A , CUI XIUMIN , CUNNINGHAM SCOTT D , DICOSIMO ROBERT , FAHNESTOCK STEPHEN R , GRUBER TANJA MARIA , HUANG YONGQING , JIANG XUEPING , PARTHASARATHY ANJU , PAYNE MARK S , ROUVIERE PIERRE E , WANG HONG
Inventor： CHISHOLM DEXTER A , CUI XIUMIN , CUNNINGHAM SCOTT D , DICOSIMO ROBERT , FAHNESTOCK STEPHEN R , GRUBER TANJA MARIA , HUANG YONGQING , JIANG XUEPING , PARTHASARATHY ANJU , PAYNE MARK S , ROUVIERE PIERRE E , WANG HONG
CPC classification number: A61K8/66 , A61K8/22 , A61K8/38 , A61K8/64 , A61K38/46 , A61K38/465 , A61Q5/08 , A61Q5/10 , A61Q9/04 , A61Q15/00 , A61Q19/00 , A61Q19/02
Abstract: Disclosed herein are compositions and methods to treat hair with a peracid-based benefit agent. The peracid benefit agent can be used for hair bleaching, hair weakening, hair removal, hair waiving, hair straightening or any combination thereof. The peracid may be enzymatically generated from a carboxylic acid ester substrate using an enzyme having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a hair-binding domain, either directly or through an optional linker, may be used to target the perhydrolytic activity to the hair surface.
Abstract translation: 本文公开了用基于过酸的有益剂处理头发的组合物和方法。 过酸有益剂可以用于头发漂白，头发弱化，脱毛，免除头发，拉直头发或其任何组合。 过酸可以使用具有过水解活性的酶（过水解酶）在过氧源存在下从羧酸酯底物酶促产生。 包含偶联至头发结合结构域的过水解酶的融合蛋白，可以直接或通过任选的接头，用于靶向头发表面的过水解活性。
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9.发明申请ENZYMATIC PERACID GENERATION FOR USE IN ORAL CARE PRODUCTS 审中-公开用于口腔护理产品的ENZYMATIC PERACID GENERATION
公开(公告)号：WO2012087970A2
公开(公告)日：2012-06-28
申请号：PCT/US2011/065912
申请日：2011-12-19
Applicant: E. I. DU PONT DE NEMOURS AND COMPANY , BUTTERICK, Lisa, A. , CUNNINGHAM, Scott, D. , DICOSIMO, Robert , FOSSER, Kari, A. , GRUBER, Tanja, Maria , HAYNIE, Sharon, L. , PAYNE, Mark, S. , ROUVIERE, Pierre, E. , WANG, Hong
Inventor： BUTTERICK, Lisa, A. , CUNNINGHAM, Scott, D. , DICOSIMO, Robert , FOSSER, Kari, A. , GRUBER, Tanja, Maria , HAYNIE, Sharon, L. , PAYNE, Mark, S. , ROUVIERE, Pierre, E. , WANG, Hong
Abstract: Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.
Abstract translation: 本文公开了用基于过酸的有益剂治疗口腔表面的组合物和方法。 过酸有益剂可用于口腔表面漂白，增白，消毒，脱色，除臭，减少或除去生物膜及其组合。 使用具有过水解活性的CE-7碳水化合物酯酶（过水解酶），在过氧化物源的存在下，由羧酸酯底物酶促产生过酸。 包含偶联于对口腔表面具有亲和力的肽组分的过水解酶的融合蛋白可以直接或通过任选的连接体用于靶向口腔表面的过水解活性。
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公开(公告)号：WO2012087966A2
公开(公告)日：2012-06-28
申请号：PCT/US2011/065902
申请日：2011-12-19
Applicant: E. I. DU PONT DE NEMOURS AND COMPANY , DICOSIMO, Robert , CUNNINGHAM, Scott, D. , FAHNESTOCK, Stephen, R. , GRUBER, Tanja, Maria , PAYNE, Mark, S. , ROUVIERE, Pierre, E. , SOLOMON, Linda, Jane , WANG, Hong
Inventor： DICOSIMO, Robert , CUNNINGHAM, Scott, D. , FAHNESTOCK, Stephen, R. , GRUBER, Tanja, Maria , PAYNE, Mark, S. , ROUVIERE, Pierre, E. , SOLOMON, Linda, Jane , WANG, Hong
CPC classification number: C12N9/18 , C07K16/16 , C07K19/00 , C07K2319/01 , C11D3/38636 , C11D3/38681 , C12N9/14 , C12N9/2437 , C12P7/40 , C12P7/54
Abstract: Disclosed herein are compositions and methods to target enzymatic peracid production to a target surface. The peracid benefit agent produced by the targeted perhydrolytic enzyme can be use for a variety of applications such as bleaching, whitening, disinfecting, destaining, deodorizing, and combinations thereof. Specifically, a fusion protein comprising a perhydrolytic enzyme and at least one peptidic component having affinity for a target surface (excluding body surfaces and oral care surfaces) is used in combination with a suitable substrate and a source of peroxygen to enzymatically produce a peracid on or near the surface of the target material. In a preferred aspect, the target surface is a cellulosic material.
Abstract translation: 本文公开了将酶过氧酸生产靶向靶表面的组合物和方法。 由靶向的水解酶产生的过酸有益剂可用于各种应用，例如漂白，增白，消毒，脱色，除臭及其组合。 特别地，包含过水解酶和至少一种对靶表面（不包括身体表面和口腔护理表面）具有亲和性的肽成分的融合蛋白与合适的底物和过氧源组合使用以在其上或 靠近目标材料的表面。 在优选的方面，目标表面是纤维素材料。
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