公开(公告)号：WO2008024948A3

公开(公告)日：2008-07-03

申请号：PCT/US2007076710

申请日：2007-08-24

Applicant: GEN HOSPITAL CORP ,  VAKOC BENJAMIN J ,  DESJARDINS ADRIEN E ,  TEARNEY GUILLERMO J ,  BOUMA EUGENE BRETT

Inventor： VAKOC BENJAMIN J ,  DESJARDINS ADRIEN E ,  TEARNEY GUILLERMO J ,  BOUMA EUGENE BRETT

IPC: G01N21/47 ,  A61B3/12

CPC classification number: A61B3/1225 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/6852

Abstract: Apparatus and method can be provided, whereas a particular radiation which includes at least one first electro-magnetic radiation can be directed to at least one sample and at least one second electro-magnetic radiation can be directed to a reference. The first electro-magnetic radiation having a particular cross-sectional width may be applied to at least one portion of the sample to generate at least one third electro-magnetic radiation. The first electro-magnetic radiation can be provided in the portion along a particular axis for a distance between a multiplier of 0.5 and 100 of the particular cross-sectional width. An interference can be detected between the third electro-magnetic radiation associated with the first electro-magnetic radiation and at least one fourth electro-magnetic radiation associated with the second electro-magnetic radiation. Further, an asymmetrical cross-sectional area of the first electro-magnetic radiation can be provided.

Abstract translation: 可以提供装置和方法，而包括至少一个第一电磁辐射的特定辐射可以被引导到至少一个样品，并且至少一个第二电磁辐射可以被引导到参考。 具有特定横截面宽度的第一电磁辐射可以被施加到样品的至少一部分以产生至少一个第三电磁辐射。 第一电磁辐射可以沿着特定轴线的部分设置在特定横截面宽度的0.5和100之间的距离上。 可以在与第一电磁辐射相关联的第三电磁辐射与与第二电磁辐射相关联的至少一个第四电磁辐射之间检测到干扰。 此外，可以提供第一电磁辐射的不对称横截面积。

公开(公告)号：WO2008024948A2

公开(公告)日：2008-02-28

申请号：PCT/US2007/076710

申请日：2007-08-24

Applicant: THE GENERAL HOSPITAL CORPORATION ,  VAKOC, Benjamin, J. ,  DESJARDINS, Adrien, E. ,  TEARNEY, Guillermo, J. ,  BOUMA, Eugene, Brett

Inventor： VAKOC, Benjamin, J. ,  DESJARDINS, Adrien, E. ,  TEARNEY, Guillermo, J. ,  BOUMA, Eugene, Brett

CPC classification number: A61B3/1225 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/6852

Abstract: Apparatus and method can be provided, whereas a particular radiation which includes at least one first electro-magnetic radiation can be directed to at least one sample and at least one second electro-magnetic radiation can be directed to a reference. The first electro-magnetic radiation having a particular cross-sectional width may be applied to at least one portion of the sample to generate at least one third electro-magnetic radiation. The first electro-magnetic radiation can be provided in the portion along a particular axis for a distance between a multiplier of 0.5 and 100 of the particular cross-sectional width. An interference can be detected between the third electro-magnetic radiation associated with the first electro-magnetic radiation and at least one fourth electro-magnetic radiation associated with the second electro-magnetic radiation. Further, an asymmetrical cross-sectional area of the first electro-magnetic radiation can be provided.

Abstract translation: 可以提供设备和方法，而包括至少一个第一电磁辐射的特定辐射可以被引导到至少一个样本，并且至少一个第二电磁辐射可以被引导到 一个参考。 具有特定横截面宽度的第一电磁辐射可被施加到样本的至少一部分以产生至少一个第三电磁辐射。 第一电磁辐射可以在沿特定轴的部分中提供0.5倍和0.5倍的特定横截面宽度之间的距离。 可以在与第一电磁辐射相关联的第三电磁辐射和与第二电磁辐射相关联的至少一个第四电磁辐射之间检测到干扰。 此外，可以提供第一电磁辐射的不对称的横截面。

公开(公告)号：WO2010086778A2

公开(公告)日：2010-08-05

申请号：PCT/IB2010/050308

申请日：2010-01-25

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HENDRIKS, Bernardus, H., W. ,  DESJARDINS, Adrien, E. ,  MCKINNEY, Martin, F.

Inventor： HENDRIKS, Bernardus, H., W. ,  DESJARDINS, Adrien, E. ,  MCKINNEY, Martin, F.

IPC: A61B19/00

CPC classification number: A61B17/3403 ,  A61B6/12 ,  A61B6/463 ,  A61B6/464 ,  A61B6/467 ,  A61B34/25 ,  A61B90/30 ,  A61B2017/00035 ,  A61B2017/00061 ,  A61B2017/00084 ,  A61B2017/00128 ,  A61B2034/107 ,  A61B2034/254 ,  A61B2090/372 ,  A61B2090/376 ,  G06F19/00 ,  G06F19/321 ,  H05B33/0803

Abstract: The present invention relates to an examination apparatus for providing information about an object and a method for providing information about an object of interest. In order to improve the visual reception of information relating to the object, an examination apparatus is provided that comprises an examination arrangement and a control unit with at least a first interface and a second interface. The examination arrangement is adapted to detect object data from at least one region of interest of an object and to provide the object data to the control unit. Further, the control unit is adapted to compute object data into object information and to transform at least a part of the object information into image data (32, 36). Further, the control unit is arranged to extract pre-determined indicative data from the object information and to transform the indicative data into graphical advisory data (40). The first interface is configured such to provide the image data to a display unit (20) in order to display the image data (32, 36) to the user. The second interface is configured such to provide a signal for an ambient advice display arrangement in order to provide the graphical advisory data (40) to the user.

Abstract translation: 本发明涉及用于提供关于对象的信息的检查装置和用于提供关于感兴趣对象的信息的方法。 为了改善与物体有关的信息的可视接收，提供了一种检查设备，其包括检查装置和具有至少第一接口和第二接口的控制单元。 检查装置适于检测来自物体的至少一个感兴趣区域的物体数据并将物体数据提供给控制单元。 此外，控制单元适于将对象数据计算为对象信息并将对象信息的至少一部分转换为图像数据（32,36）。 此外，控制单元布置成从对象信息中提取预定的指示数据并将指示数据转换为图形咨询数据（40）。 第一界面被配置为将图像数据提供给显示单元（20）以便向用户显示图像数据（32,36）。 第二界面被配置为提供用于环境建议显示布置的信号，以便向用户提供图形咨询数据（40）。

公开(公告)号：WO2010084445A1

公开(公告)日：2010-07-29

申请号：PCT/IB2010/050208

申请日：2010-01-18

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  DESJARDINS, Adrien, E. ,  VAN DER MARK, Martinus, B. ,  HENDRIKS, Bernardus, H., W. ,  'T HOOFT, Gert

Inventor： DESJARDINS, Adrien, E. ,  VAN DER MARK, Martinus, B. ,  HENDRIKS, Bernardus, H., W. ,  'T HOOFT, Gert

IPC: A61B5/00

CPC classification number: A61B5/0075 ,  A61B5/0062 ,  A61B5/0084 ,  A61B5/6848

Abstract: An optical examination device (10) adapted to be at least partially inserted into a turbid medium is provided. The optical examination device comprises a shaft portion (21) adapted to be inserted into the turbid medium, the shaft portion (21) comprising a tip portion (22) adapted to be the foremost portion during insertion into the turbid medium. At least one light source device adapted to emit abeam (11) of broad-band light is provided in the region of the tip portion (21). The beam (11) of broad-band light comprises different wavelength bands (2a, 2b,..., 2n) which are differently modulated. At least one photodetector (27a, 27b, 27c) for detecting broad-band light is provided in a region adapted to be inserted into the turbid medium of the shaft portion (21).

Abstract translation: 提供了适于至少部分地插入混浊介质中的光学检查装置（10）。 光学检查装置包括适于插入混浊介质的轴部分（21），该轴部分（21）包括在插入混浊介质期间适于最前部分的末端部分（22）。 在尖端部分（21）的区域中设置适于发射宽带光的光束（11）的至少一个光源装置。 宽带光束（11）包括不同调制的不同波长带（2a，2b，...，2n）。 用于检测宽带光的至少一个光电检测器（27a，27b，27c）设置在适于插入到轴部（21）的混浊介质中的区域中。

公开(公告)号：WO2010049854A1

公开(公告)日：2010-05-06

申请号：PCT/IB2009/054644

申请日：2009-10-21

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HEZEMANS, Cornelius, A. ,  HENDRIKS, Bernardus, H., W. ,  BIERHOFF, Waltherus, C., J. ,  BRAUN, Augustinus, L. ,  DESJARDINS, Adrien, E.

Inventor： HEZEMANS, Cornelius, A. ,  HENDRIKS, Bernardus, H., W. ,  BIERHOFF, Waltherus, C., J. ,  BRAUN, Augustinus, L. ,  DESJARDINS, Adrien, E.

IPC: A61B1/00 ,  A61B1/07 ,  A61B5/00 ,  A61B19/00

CPC classification number: A61B1/00188 ,  A61B1/00096 ,  A61B1/00163 ,  A61B1/00165 ,  A61B5/0062 ,  A61B5/0084 ,  A61B5/061 ,  A61B5/062 ,  A61B5/065 ,  A61B34/73 ,  A61B90/361 ,  A61B2034/2051

Abstract: This invention relates to an optical probe (200) and an optical imaging system, including an optical guide (201) having a proximal end and a distal end, an actuation means having driving coils (204) and a magnet, with of which being attached to the optical guide. By supplying a driving current through the driving coils a magnetic flux is generated which interacts with the magnet forming a driving force acting at on the optical guide causing a displacement of the distal end of the optical guide. A position measuring including a position measuring coil (205) is used for monitoring the position of the optical guide, where the internal arrangement of the position measuring coil and the driving coils is such that said displacement of the distal end of the optical guide causes a change in the internal arrangement. A power supply supplies an additional high frequency alternating current (AC) through the driving coils which causes an induced voltage in the position measuring coil and thus generates a magnetic coupling between the position measuring coil and the driving coils. A position measuring means measures the displacement of the distal end of the optical guide by means of measuring the induced voltage resulting in when the internal arrangement changes. This induced voltage change being indicative for the position of the distal end.

Abstract translation: 本发明涉及一种光学探针（200）和光学成像系统，其包括具有近端和远端的光导（201），具有驱动线圈（204）和磁铁的致动装置 到光导。 通过提供驱动电流通过驱动线圈产生与磁体相互作用的磁通，形成作用在光导上的驱动力，导致光导的远端位移。 包括位置测量线圈（205）的位置测量用于监测光导的位置，其中位置测量线圈和驱动线圈的内部布置使得光导的远端的所述位移导致 改变内部安排。 电源通过驱动线圈提供额外的高频交流电，这导致位置测量线圈中的感应电压，从而在位置测量线圈和驱动线圈之间产生磁耦合。 位置测量装置通过测量导致当内部布置改变的感应电压来测量光导的远端的位移。 该感应电压变化指示远端的位置。

公开(公告)号：WO2010136922A1

公开(公告)日：2010-12-02

申请号：PCT/IB2010/052030

申请日：2010-05-07

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  BAKKER, Levinus, P. ,  HENDRIKS, Bernardus, H., W. ,  DESJARDINS, Adrien, E.

Inventor： BAKKER, Levinus, P. ,  HENDRIKS, Bernardus, H., W. ,  DESJARDINS, Adrien, E.

IPC: A61B5/00 ,  G06T7/00 ,  A61B19/00 ,  A61B6/12

CPC classification number: A61B8/0841 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0073 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/6848 ,  A61B6/12 ,  A61B6/5247 ,  A61B8/00 ,  A61B8/5238 ,  A61B17/34 ,  A61B17/3403 ,  A61B17/3417 ,  A61B2090/3614 ,  A61B2090/374 ,  A61B2090/376 ,  A61B2090/378 ,  A61B2090/3784

Abstract: Re-calibration of pre-recorded images during interventions is proposed, utilizing an interventional system comprising an imaging device providing images of an object, a needle device, and a processing device. The needle device comprises a sensor for providing data corresponding to tissue properties. The processing device is adapted to perform an overlay registration of pre-recorded images and live images provided by the imaging device, utilizing the data from the sensor. Thus, the accuracy of an overlay of images is increased.

Abstract translation: 提出了在干预期间重新校准预先记录的图像，利用包括提供物体，针装置和处理装置的图像的成像装置的介入系统。 针装置包括用于提供对应于组织性质的数据的传感器。 处理装置适用于利用来自传感器的数据来执行由成像装置提供的预先记录的图像和实况图像的重叠注册。 因此，图像的重叠的精度增加。

公开(公告)号：WO2007101026A2

公开(公告)日：2007-09-07

申请号：PCT/US2007/062465

申请日：2007-02-21

Applicant: THE GENERAL HOSPITAL CORPORATION ,  DESJARDINS, Adrien, E. ,  VAKOC, Benjamin, J. ,  TEANEY, Guillermo, J. ,  BOUMA, Brett, E.

Inventor： DESJARDINS, Adrien, E. ,  VAKOC, Benjamin, J. ,  TEANEY, Guillermo, J. ,  BOUMA, Brett, E.

IPC: G01B9/02 ,  G01N21/47 ,  A61B5/00

CPC classification number: G01N21/4795 ,  A61B5/0066 ,  A61B5/0073 ,  G01B9/02043 ,  G01B9/02087 ,  G01B9/02091 ,  G01B2290/70 ,  G01N2021/4714

Abstract: Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro- magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations.

Abstract translation: 根据本发明的示例性实施例提供了安排，装置和方法。 特别地，可以接收至少一个第一电磁辐射，并且将立体角内的至少一个第二电磁辐射转发到样品。 第二电磁辐射可以与第一电磁辐射相关联。 可以从与第二电磁辐射相关联的样品接收多个第三电磁辐射，并且第三电磁辐射的至少一部分设置在立体角的外围。 可以同时检测与每个第三电磁辐射相关联的信号，其中信号与样品在其多个深度处的信息相关联。 可以使用第三电磁辐射中的至少一个来确定深度，而不需要利用第三电磁辐射中的另一个。

公开(公告)号：WO2010086778A3

公开(公告)日：2010-09-30

申请号：PCT/IB2010050308

申请日：2010-01-25

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  HENDRIKS BERNARDUS H W ,  DESJARDINS ADRIEN E ,  MCKINNEY MARTIN F

Inventor： HENDRIKS BERNARDUS H W ,  DESJARDINS ADRIEN E ,  MCKINNEY MARTIN F

IPC: A61B19/00 ,  H05B37/02

CPC classification number: A61B17/3403 ,  A61B6/12 ,  A61B6/463 ,  A61B6/464 ,  A61B6/467 ,  A61B34/25 ,  A61B90/30 ,  A61B2017/00035 ,  A61B2017/00061 ,  A61B2017/00084 ,  A61B2017/00128 ,  A61B2034/107 ,  A61B2034/254 ,  A61B2090/372 ,  A61B2090/376 ,  G06F19/321 ,  H05B33/0803

Abstract: The present invention relates to an examination apparatus for providing information about an object and a method for providing information about an object of interest. In order to improve the visual reception of information relating to the object, an examination apparatus is provided that comprises an examination arrangement and a control unit with at least a first interface and a second interface. The examination arrangement is adapted to detect object data from at least one region of interest of an object and to provide the object data to the control unit. Further, the control unit is adapted to compute object data into object information and to transform at least a part of the object information into image data (32, 36). Further, the control unit is arranged to extract pre-determined indicative data from the object information and to transform the indicative data into graphical advisory data (40). The first interface is configured such to provide the image data to a display unit (20) in order to display the image data (32, 36) to the user. The second interface is configured such to provide a signal for an ambient advice display arrangement in order to provide the graphical advisory data (40) to the user.

Abstract translation: 本发明涉及一种用于提供关于对象的信息的检查装置和用于提供关于感兴趣对象的信息的方法。 为了改善与对象有关的信息的视觉接收，提供一种包括检查装置和至少具有第一接口和第二接口的控制单元的检查装置。 检查装置适于从对象的至少一个感兴趣区域检测对象数据，并将对象数据提供给控制单元。 此外，控制单元适于将对象数据计算为对象信息并将至少一部分对象信息转换为图像数据（32,36）。 此外，控制单元被布置为从对象信息中提取预定指示数据，并将指示性数据变换成图形咨询数据（40）。 第一接口被配置为将图像数据提供给显示单元（20），以便向用户显示图像数据（32,36）。 第二接口被配置为提供用于环境咨询显示装置的信号，以向用户提供图形咨询数据（40）。

公开(公告)号：WO2010067281A1

公开(公告)日：2010-06-17

申请号：PCT/IB2009/055498

申请日：2009-12-04

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HENDRIKS, Bernardus, H., W. ,  DESJARDINS, Adrien, E. ,  BABIC, Drazenko

Inventor： HENDRIKS, Bernardus, H., W. ,  DESJARDINS, Adrien, E. ,  BABIC, Drazenko

IPC: A61B6/00

CPC classification number: A61B6/5235 ,  A61B6/4423 ,  A61B6/4441 ,  A61B6/5247 ,  A61B90/361 ,  A61B2090/364 ,  A61B2090/366 ,  A61B2090/371 ,  A61B2090/376

Abstract: The invention relates to a system (102) for generating an image comprising information of both an interior and an exterior of a patient (114). The system comprises an X ray device (104) for providing an X ray image of a patient's interior and a camera (124) responsive to a wavelength for providing a camera image of a patient's exterior. Herein, the camera (124) is supported by the X ray device (104) for establishing a determined spatial relationship between the camera (124) and the X ray device (104). The system (102) furthermore comprises a spatial reference for spatially correlating the X ray image and the camera image, which spatial reference is detectable in the X ray image and in the camera image. A data processor (126) is comprised for rendering the camera image and the X ray image into a composite image on the basis of the spatial reference. The system increases a medical professional's ability to efficiently perform an image guided medical intervention.

Abstract translation: 本发明涉及一种用于生成包括患者（114）的内部和外部的信息的图像的系统（102）。 该系统包括用于提供患者内部的X射线图像的X射线装置（104）和响应于用于提供患者外部的照相机图像的波长的照相机（124）。 这里，相机（124）由X射线装置（104）支撑，用于建立照相机（124）和X射线装置（104）之间确定的空间关系。 系统（102）还包括用于空间相关X射线图像和相机图像的空间参考，该空间参考在X射线图像和相机图像中是可检测的。 包括数据处理器（126），用于基于空间参考将相机图像和X射线图像渲染成合成图像。 该系统增加了医疗专业人员有效执行图像导向医疗干预的能力。

公开(公告)号：WO2010058344A1

公开(公告)日：2010-05-27

申请号：PCT/IB2009/055128

申请日：2009-11-18

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  HENDRIKS, Bernardus, H., W. ,  BRAUN, Augustinus, L. ,  HARBERS, Rik ,  VAN DER VOORT, Marjolein ,  DESJARDINS, Adrien, E. ,  NACHABE, Rami

Inventor： HENDRIKS, Bernardus, H., W. ,  BRAUN, Augustinus, L. ,  HARBERS, Rik ,  VAN DER VOORT, Marjolein ,  DESJARDINS, Adrien, E. ,  NACHABE, Rami

IPC: A61B5/00 ,  A61B10/00

CPC classification number: A61B5/0084 ,  A61B5/0075 ,  A61B5/1459 ,  A61B5/6848 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/3401 ,  A61B18/1477 ,  A61B2017/00057 ,  A61B2018/1425

Abstract: Needle interventions are widely used in the field of oncology for taking biopsies of tissue in order to inspect whether tissue is cancerous or not. To make these interventions more reliable feedback of what kind of tissue is in front of the needle is required. A way to achieve this is by making use of optical spectroscopy. This requires integration of fibers into the needle. These fibers are used to deliver light to illuminate the tissue in front of the needle and to collect back the reflected light from the tissue. The present invention proposes to integrate the fiber distal ends in the slanted bevel of the needle in such a way that at least one source-detector fiber pair has a distance that is larger than the outer diameter of the needle.

Abstract translation: 针刺干预广泛用于肿瘤学领域，用于检查组织的活组织检查，以检查组织是否是癌性的。 要使这些干预措施更加可靠，就需要针头前面的什么样的组织的反馈信息。 实现这一目标的一个方法是利用光谱学。 这需要将纤维整合到针中。 这些纤维用于传递光以照射针前面的组织并收集来自组织的反射光。 本发明提出将光纤远端整合到针的倾斜斜面中，使得至少一个源 - 检测器光纤对的距离大于针的外径。